메뉴 건너뛰기




Volumn 27, Issue 6, 2004, Pages 377-387

Functional component of portal hypertension;Componente funcional de la hipertensión portal

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ARACHIDONATE 5 LIPOXYGENASE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CANNABINOID; CARBON MONOXIDE; GLUCAGON; NITRIC OXIDE; NITRIC OXIDE DONOR; PROSTACYCLIN; SOMATOSTATIN DERIVATIVE; VASOCONSTRICTOR AGENT; VASODILATOR AGENT; VASOPRESSIN DERIVATIVE;

EID: 3142777237     PISSN: 02105705     EISSN: None     Source Type: Journal    
DOI: 10.1157/13062895     Document Type: Review
Times cited : (3)

References (135)
  • 1
    • 0021845701 scopus 로고
    • Localization of increased hepatic vascular resistance in liver cirrhosis
    • Shibayama Y, Nakata K. Localization of increased hepatic vascular resistance in liver cirrhosis. Hepatology 1985;5:643-7.
    • (1985) Hepatology , vol.5 , pp. 643-647
    • Shibayama, Y.1    Nakata, K.2
  • 2
  • 3
    • 0034053015 scopus 로고    scopus 로고
    • Complications of cirrhosis. 1. Portal hypertension
    • Bosch J, García-Pagán JC. Complications of cirrhosis. 1. Portal hypertension. J Hepatol 2000;32:141-56.
    • (2000) J Hepatol , vol.32 , pp. 141-156
    • Bosch, J.1    García-Pagán, J.C.2
  • 4
    • 0033537342 scopus 로고    scopus 로고
    • Bacterial infection in the pathogenesis of variceal bleeding
    • Goulis J, Patch D, Burroughs AK. Bacterial infection in the pathogenesis of variceal bleeding. Lancet 1999;353:139-42.
    • (1999) Lancet , vol.353 , pp. 139-142
    • Goulis, J.1    Patch, D.2    Burroughs, A.K.3
  • 5
    • 0027973463 scopus 로고
    • Renal impairment after spontaneous bacterial peritonitis in cirrhosis: Incidence, clinical course, predictive factors and prognosis
    • Follo A, Llovet JM, Navasa M, Planas R, Forns X, Francitorra A, et al. Renal impairment after spontaneous bacterial peritonitis in cirrhosis: incidence, clinical course, predictive factors and prognosis. Hepatology 1994;20:1495-501.
    • (1994) Hepatology , vol.20 , pp. 1495-1501
    • Follo, A.1    Llovet, J.M.2    Navasa, M.3    Planas, R.4    Forns, X.5    Francitorra, A.6
  • 6
    • 0342980277 scopus 로고    scopus 로고
    • Influence of pharmacological agents on portal hemodynamics: Basis for its use in the treatment of portal hypertension
    • García-Pagán JC, Escorsell A, Moitinho E, Bosch J. Influence of pharmacological agents on portal hemodynamics: basis for its use in the treatment of portal hypertension. Semin Liver Dis 1999;19:427-38.
    • (1999) Semin Liver Dis , vol.19 , pp. 427-438
    • García-Pagán, J.C.1    Escorsell, A.2    Moitinho, E.3    Bosch, J.4
  • 7
    • 0033749190 scopus 로고    scopus 로고
    • Regression of human cirrhosis. Morphologic features and the genesis of incomplete septal cirrhosis
    • Wanless IR, Nakashima E, Sherman M. Regression of human cirrhosis. Morphologic features and the genesis of incomplete septal cirrhosis. Arch Pathol Lab Med 2000;124:1599-607.
    • (2000) Arch Pathol Lab Med , vol.124 , pp. 1599-1607
    • Wanless, I.R.1    Nakashima, E.2    Sherman, M.3
  • 8
    • 0022468986 scopus 로고
    • Interaction of flow and resistance in maintenance of portal hypertension in a rat model
    • Sikuler E, Groszmann RJ. Interaction of flow and resistance in maintenance of portal hypertension in a rat model. Am J Physiol 1986;250:G205-G12.
    • (1986) Am J Physiol , vol.250
    • Sikuler, E.1    Groszmann, R.J.2
  • 9
    • 3142678910 scopus 로고    scopus 로고
    • Portal hypertension
    • Schiff ER, Sorrell MF, Maddrey WC, editors. Philadelphia: Lippincott Williams & Wilkins
    • th ed. Philadelphia: Lippincott Williams & Wilkins, 2003; p. 429-86.
    • (2003) th Ed. , pp. 429-486
    • Bosch, J.1    D'Amico, G.2    García-Pagán, J.C.3
  • 10
    • 0029048868 scopus 로고
    • Hepatic and portal vein thrombosis in cirrhosis: Possible role in development of parenchymal extinction and portal hypertension
    • Wanless IR, Wong F, Blendis LM, Greig P, Heathcote EJ, Levy G. Hepatic and portal vein thrombosis in cirrhosis: possible role in development of parenchymal extinction and portal hypertension. Hepatology 1995;21:1238-47.
    • (1995) Hepatology , vol.21 , pp. 1238-1247
    • Wanless, I.R.1    Wong, F.2    Blendis, L.M.3    Greig, P.4    Heathcote, E.J.5    Levy, G.6
  • 11
    • 0021816284 scopus 로고
    • Reduction of the increased portal vascular resistance of the isolated perfused cirrhotic rat liver by vasodilators
    • Bathal PS, Grossmann HJ. Reduction of the increased portal vascular resistance of the isolated perfused cirrhotic rat liver by vasodilators. J Hepatol 1985;1:325-9.
    • (1985) J Hepatol , vol.1 , pp. 325-329
    • Bathal, P.S.1    Grossmann, H.J.2
  • 13
    • 0033450924 scopus 로고    scopus 로고
    • Biology of hepatic stellate cells and their possible relevance in the pathogenesis of portal hypertension in cirrhosis
    • Pinzani M, Gentilini P. Biology of hepatic stellate cells and their possible relevance in the pathogenesis of portal hypertension in cirrhosis. Semin Liver Dis 1999;19:397-410.
    • (1999) Semin Liver Dis , vol.19 , pp. 397-410
    • Pinzani, M.1    Gentilini, P.2
  • 14
    • 0026775513 scopus 로고
    • Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients
    • Pinzani M, Failli P, Ruocco C, Casini A, Milani S, Baldi E, et al. Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients. J Clin Invest 1992;90:642-6.
    • (1992) J Clin Invest , vol.90 , pp. 642-646
    • Pinzani, M.1    Failli, P.2    Ruocco, C.3    Casini, A.4    Milani, S.5    Baldi, E.6
  • 16
    • 0030795418 scopus 로고    scopus 로고
    • Arginine vasopressin induces contraction and stimulates growth of cultured human hepatic stellate cells
    • Bataller R, Nicolás JM, Ginés P, Esteve A, Nieves GM, García-Ramallo E, et al. Arginine vasopressin induces contraction and stimulates growth of cultured human hepatic stellate cells. Gastroenterology 1997;113:615-24.
    • (1997) Gastroenterology , vol.113 , pp. 615-624
    • Bataller, R.1    Nicolás, J.M.2    Ginés, P.3    Esteve, A.4    Nieves, G.M.5    García-Ramallo, E.6
  • 17
    • 20644446505 scopus 로고    scopus 로고
    • Atrial natriuretic peptide antagonizes endothelin-induced calcium increase and cell contraction in cultured human hepatic stellate cells
    • Gorbig MN, Ginés P, Bataller R, Nicolás JM, García-Ramallo E, Tobias E, et al. Atrial natriuretic peptide antagonizes endothelin-induced calcium increase and cell contraction in cultured human hepatic stellate cells. Hepatology 1999;30:501-9.
    • (1999) Hepatology , vol.30 , pp. 501-509
    • Gorbig, M.N.1    Ginés, P.2    Bataller, R.3    Nicolás, J.M.4    García-Ramallo, E.5    Tobias, E.6
  • 18
    • 0029891589 scopus 로고    scopus 로고
    • Endothelin induced contractility of stellate cells from normal and cirrhotic rat liver: Implications for regulation of portal pressure and resistance
    • Rockey DC, Weisiger RA. Endothelin induced contractility of stellate cells from normal and cirrhotic rat liver: implications for regulation of portal pressure and resistance. Hepatology 1996;24:233-40.
    • (1996) Hepatology , vol.24 , pp. 233-240
    • Rockey, D.C.1    Weisiger, R.A.2
  • 19
    • 0027190038 scopus 로고
    • The contraction of hepatic stellate (lto) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus
    • Kawada N, Tran-Thi TA, Klein H, Decker K. The contraction of hepatic stellate (lto) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur J Biochem 1993;213:815-23.
    • (1993) Eur J Biochem , vol.213 , pp. 815-823
    • Kawada, N.1    Tran-Thi, T.A.2    Klein, H.3    Decker, K.4
  • 20
    • 0031961808 scopus 로고    scopus 로고
    • Nitric oxide suppression reversibly attenuates mitochondrial dysfunction and cholestasis in endotoxemic rat liver
    • Shiomi M, Wakabayashi Y, Sano T, Shinoda Y, Nimura Y, Ishimura Y, et al. Nitric oxide suppression reversibly attenuates mitochondrial dysfunction and cholestasis in endotoxemic rat liver. Hepatology 1998;27:108-15.
    • (1998) Hepatology , vol.27 , pp. 108-115
    • Shiomi, M.1    Wakabayashi, Y.2    Sano, T.3    Shinoda, Y.4    Nimura, Y.5    Ishimura, Y.6
  • 21
    • 0031952913 scopus 로고    scopus 로고
    • Endothelin-1 induced vasoconstriction causes a significant increase in portal pressure of rat liver: Localized constrictive effect on the the distal segment of preterminal portal venules as revealed by light and electron microscopy and serial reconstruction
    • Kaneda K, Sogawa M, Matsumara A, Cho A, Kawada N. Endothelin-1 induced vasoconstriction causes a significant increase in portal pressure of rat liver: localized constrictive effect on the the distal segment of preterminal portal venules as revealed by light and electron microscopy and serial reconstruction. Hepatology 1998;27:735-47.
    • (1998) Hepatology , vol.27 , pp. 735-747
    • Kaneda, K.1    Sogawa, M.2    Matsumara, A.3    Cho, A.4    Kawada, N.5
  • 22
    • 0345118191 scopus 로고    scopus 로고
    • Deficit in nitric oxide production in cirrhotic rat livers is located in the sinusoidal and postsinusoidal areas
    • Loureiro-Silva MR, Cadelina GW, Groszmann RJ. Deficit in nitric oxide production in cirrhotic rat livers is located in the sinusoidal and postsinusoidal areas. Am J Physiol Gastrointest Liver Physiol 2003;284:G567-G74.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284
    • Loureiro-Silva, M.R.1    Cadelina, G.W.2    Groszmann, R.J.3
  • 23
    • 0031442394 scopus 로고    scopus 로고
    • Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids
    • Shah V, Haddad FG, García-Cardena G, Frangos JA, Mennone A, Groszmann RJ, et al. Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids. J Clin Invest 1997;100:2923-30.
    • (1997) J Clin Invest , vol.100 , pp. 2923-2930
    • Shah, V.1    Haddad, F.G.2    García-Cardena, G.3    Frangos, J.A.4    Mennone, A.5    Groszmann, R.J.6
  • 25
    • 0031682956 scopus 로고    scopus 로고
    • Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats
    • Gupta TK, Toruner M, Chung MK, Groszmann RJ. Endothelial dysfunction and decreased production of nitric oxide in the intrahepatic microcirculation of cirrhotic rats. Hepatology 1998;28:926-31.
    • (1998) Hepatology , vol.28 , pp. 926-931
    • Gupta, T.K.1    Toruner, M.2    Chung, M.K.3    Groszmann, R.J.4
  • 26
    • 0031941122 scopus 로고    scopus 로고
    • Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: Endothelial dysfunction in portal hypertension
    • Rockey DC, Chung JJ. Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension. Gastroenterology 1998;114:344-51.
    • (1998) Gastroenterology , vol.114 , pp. 344-351
    • Rockey, D.C.1    Chung, J.J.2
  • 27
    • 0032738990 scopus 로고    scopus 로고
    • Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat
    • Shah V, Toruner M, Haddad F, Cadelina G, Papapetropoulos A, Choo K, et al. Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat. Gastroenterology 1999;117:1222-8.
    • (1999) Gastroenterology , vol.117 , pp. 1222-1228
    • Shah, V.1    Toruner, M.2    Haddad, F.3    Cadelina, G.4    Papapetropoulos, A.5    Choo, K.6
  • 29
    • 0036154951 scopus 로고    scopus 로고
    • The paradox of nitric oxide in cirrhosis and portal hypertension: Too much, not enough
    • Wiest R, Groszmann RJ. The paradox of nitric oxide in cirrhosis and portal hypertension: too much, not enough. Hepatology 2002;35:478-91.
    • (2002) Hepatology , vol.35 , pp. 478-491
    • Wiest, R.1    Groszmann, R.J.2
  • 30
    • 0037308223 scopus 로고    scopus 로고
    • Low doses of isosorbide mononitrate attenuate the postprandial increase in portal pressure in patients with cirrhosis
    • Bellis L, Berzigotti A, Abraldes JG, Moitinho E, García- Pagán JC, Bosch J, et al. Low doses of isosorbide mononitrate attenuate the postprandial increase in portal pressure in patients with cirrhosis. Hepatology 2003;37:378-84.
    • (2003) Hepatology , vol.37 , pp. 378-384
    • Bellis, L.1    Berzigotti, A.2    Abraldes, J.G.3    Moitinho, E.4    García- Pagán, J.C.5    Bosch, J.6
  • 31
    • 0036719232 scopus 로고    scopus 로고
    • In vivo gene transfer of endothelial nitric oxide synthase decreases portal pressure in anaesthetised carbon tetrachloride cirrhotic rats
    • Van de CM, Omasta A, Janssens S, Roskams T, Desmet V, Nevens F, et al. In vivo gene transfer of endothelial nitric oxide synthase decreases portal pressure in anaesthetised carbon tetrachloride cirrhotic rats. Gut 2002;51:440-5.
    • (2002) Gut , vol.51 , pp. 440-445
    • Van De, C.M.1    Omasta, A.2    Janssens, S.3    Roskams, T.4    Desmet, V.5    Nevens, F.6
  • 32
    • 0035192750 scopus 로고    scopus 로고
    • Post-translational control of endothelial nitric oxide synthase: Why isn't calcium/calmodulin enough?
    • Fulton D, Gratton JP, Sessa WC. Post-translational control of endothelial nitric oxide synthase: why isn't calcium/calmodulin enough? J Pharmacol Exp Ther 2001;299:818-24.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 818-824
    • Fulton, D.1    Gratton, J.P.2    Sessa, W.C.3
  • 33
    • 0036274032 scopus 로고    scopus 로고
    • Enhanced expression of endothelial nitric oxide synthase and caveolin-1 in human cirrhosis
    • Yokomori H, Oda M, Ogi M, Sakai K, Ishii H. Enhanced expression of endothelial nitric oxide synthase and caveolin-1 in human cirrhosis. Liver 2002;22:150-8.
    • (2002) Liver , vol.22 , pp. 150-158
    • Yokomori, H.1    Oda, M.2    Ogi, M.3    Sakai, K.4    Ishii, H.5
  • 35
    • 0036321638 scopus 로고    scopus 로고
    • Bioactivation of nitroglycerin and vasomotor response to nitric oxide are impaired in cirrhotic rat livers
    • Dudenhoefer AA, Loureiro-Silva MR, Cadelina GW, Gupta T, Groszmann RJ. Bioactivation of nitroglycerin and vasomotor response to nitric oxide are impaired in cirrhotic rat livers. Hepatology 2002;36:381-5.
    • (2002) Hepatology , vol.36 , pp. 381-385
    • Dudenhoefer, A.A.1    Loureiro-Silva, M.R.2    Cadelina, G.W.3    Gupta, T.4    Groszmann, R.J.5
  • 36
    • 2942519830 scopus 로고    scopus 로고
    • Low NO bioavailability in CCl4 cirrhotic rat livers might result from low NO synthesis combined with decreased superoxide dismutase activity allowing superoxide-mediated NO breakdown: A comparison of two portal hypertensive rat models with healthy controls
    • Van De CM, Van Pelt JF, Nevens F, Fevery J, Reichen J. Low NO bioavailability in CCl4 cirrhotic rat livers might result from low NO synthesis combined with decreased superoxide dismutase activity allowing superoxide-mediated NO breakdown: a comparison of two portal hypertensive rat models with healthy controls. Comp Hepatol 2003;2:2.
    • (2003) Comp Hepatol , vol.2 , pp. 2
    • Van De, C.M.1    Van Pelt, J.F.2    Nevens, F.3    Fevery, J.4    Reichen, J.5
  • 37
    • 0035902558 scopus 로고    scopus 로고
    • NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension
    • Fiorucci S, Antonelli E, Morelli O, Mencarelli A, Casini A, Mello T, et al. NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension. Proc Natl Acad Sci U S A 2001;98:8897-902.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 8897-8902
    • Fiorucci, S.1    Antonelli, E.2    Morelli, O.3    Mencarelli, A.4    Casini, A.5    Mello, T.6
  • 38
    • 0034121518 scopus 로고    scopus 로고
    • Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension
    • Yu Q, Shao R, Qian HS, George SE, Rockey DC. Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension. J Clin Invest 2000;105:741-8.
    • (2000) J Clin Invest , vol.105 , pp. 741-748
    • Yu, Q.1    Shao, R.2    Qian, H.S.3    George, S.E.4    Rockey, D.C.5
  • 39
    • 0025243721 scopus 로고
    • Long-term haemodynamic effects of isosorbide 5-mono-nitrate in patients with cirrhosis and portal hypertension
    • García-Pagán JC, Feu F, Navasa M, Bru C, Ruiz A, Bosch J, et al. Long-term haemodynamic effects of isosorbide 5-mono-nitrate in patients with cirrhosis and portal hypertension. J Hepatol 1990;11:189-95.
    • (1990) J Hepatol , vol.11 , pp. 189-195
    • García-Pagán, J.C.1    Feu, F.2    Navasa, M.3    Bru, C.4    Ruiz, A.5    Bosch, J.6
  • 42
    • 0347906012 scopus 로고    scopus 로고
    • A liver-specific nitric oxide donor improves the intra-hepatic vascular response to both portal blood flow increase and methoxamine in cirrhotic rats
    • Loureiro-Silva MR, Cadelina G, Iwakiri Y, Groszmann RJ. A liver-specific nitric oxide donor improves the intra-hepatic vascular response to both portal blood flow increase and methoxamine in cirrhotic rats. J Hepatol 2003;39:940-6.
    • (2003) J Hepatol , vol.39 , pp. 940-946
    • Loureiro-Silva, M.R.1    Cadelina, G.2    Iwakiri, Y.3    Groszmann, R.J.4
  • 44
    • 0028856163 scopus 로고
    • Carbon monoxide: An endogenous modulator of sinusoidal tone in the perfused rat liver
    • Suematsu M, Goda N, Sano T, Kashiwagi S, Egawa T, Shinoda Y, et al. Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver. J Clin Invest 1995;96:2431-7.
    • (1995) J Clin Invest , vol.96 , pp. 2431-2437
    • Suematsu, M.1    Goda, N.2    Sano, T.3    Kashiwagi, S.4    Egawa, T.5    Shinoda, Y.6
  • 45
    • 18244420268 scopus 로고    scopus 로고
    • Carbon monoxide overproduced by heme oxygenase-1 causes a reduction of vascular resistance in perfused rat liver
    • Wakabayashi Y, Takamiya R, Mizuki A, Kyokane T, Goda N, Yamaguchi T, et al. Carbon monoxide overproduced by heme oxygenase-1 causes a reduction of vascular resistance in perfused rat liver. Am J Physiol 1999;277:G1088-G96.
    • (1999) Am J Physiol , vol.277
    • Wakabayashi, Y.1    Takamiya, R.2    Mizuki, A.3    Kyokane, T.4    Goda, N.5    Yamaguchi, T.6
  • 46
    • 0035196917 scopus 로고    scopus 로고
    • Altered expression of heme oxygenase-1 in the livers of patients with portal hypertensive diseases
    • Makino N, Suematsu M, Sugiura Y, Morikawa H, Shiomi S, Goda N, et al. Altered expression of heme oxygenase-1 in the livers of patients with portal hypertensive diseases. Hepatology 2001;33:32-42.
    • (2001) Hepatology , vol.33 , pp. 32-42
    • Makino, N.1    Suematsu, M.2    Sugiura, Y.3    Morikawa, H.4    Shiomi, S.5    Goda, N.6
  • 47
    • 0023874715 scopus 로고
    • Differential response of normal and cirrhotic liver to vasoactive agents. A study in the isolated perfused rat liver
    • Ballet F, Chretien Y, Rey C, Poupon R. Differential response of normal and cirrhotic liver to vasoactive agents. A study in the isolated perfused rat liver. J Pharmaco Exp Ther 1988;244:233-5.
    • (1988) J Pharmaco Exp Ther , vol.244 , pp. 233-235
    • Ballet, F.1    Chretien, Y.2    Rey, C.3    Poupon, R.4
  • 50
    • 0033852479 scopus 로고    scopus 로고
    • Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis
    • Titos E, Claria J, Bataller R, Bosch-Marce M, Ginés P, Jiménez W, et al. Hepatocyte-derived cysteinyl leukotrienes modulate vascular tone in experimental cirrhosis. Gastroenterology 2000;119:794-805.
    • (2000) Gastroenterology , vol.119 , pp. 794-805
    • Titos, E.1    Claria, J.2    Bataller, R.3    Bosch-Marce, M.4    Ginés, P.5    Jiménez, W.6
  • 51
    • 0030059990 scopus 로고    scopus 로고
    • Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells
    • Pinzani M, Milani S, De Franco R, Grappone C, Caligiuri A, Gentilini A, et al. Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells. Gastroenterology 1996;110:534-48.
    • (1996) Gastroenterology , vol.110 , pp. 534-548
    • Pinzani, M.1    Milani, S.2    De Franco, R.3    Grappone, C.4    Caligiuri, A.5    Gentilini, A.6
  • 52
    • 0029051762 scopus 로고
    • Endothelin-1 and endothelin-3 in cirrhosis: Relations to systemic and splanchnic haemodynamics
    • Moller S, Gulberg V, Henriksen JH, Gerbes AL. Endothelin-1 and endothelin-3 in cirrhosis: relations to systemic and splanchnic haemodynamics. J Hepatol 1995;23:135-44.
    • (1995) J Hepatol , vol.23 , pp. 135-144
    • Moller, S.1    Gulberg, V.2    Henriksen, J.H.3    Gerbes, A.L.4
  • 53
    • 0018915843 scopus 로고
    • Hepatic hemodynamics and the renin-angiotensin-aldosterone system in cirrhosis
    • Bosch J, Arroyo V, Betriu A, Mas A, Carrilho F, Rivera F, et al. Hepatic hemodynamics and the renin-angiotensin-aldosterone system in cirrhosis. Gastroenterology 1980;78:92-9.
    • (1980) Gastroenterology , vol.78 , pp. 92-99
    • Bosch, J.1    Arroyo, V.2    Betriu, A.3    Mas, A.4    Carrilho, F.5    Rivera, F.6
  • 54
    • 0020567626 scopus 로고
    • Sympathetic nervous activity, renin-angiotensin system and renal excretion of prostaglandin E2 in cirrhosis. Relationship to functional renal failure and sodium and water excretion
    • Arroyo V, Planas R, Gaya J, Deulofeu R, Rimola A, Pérez-Ayuso RM, et al. Sympathetic nervous activity, renin-angiotensin system and renal excretion of prostaglandin E2 in cirrhosis. Relationship to functional renal failure and sodium and water excretion. Eur J Clin Invest 1983;13:271-8.
    • (1983) Eur J Clin Invest , vol.13 , pp. 271-278
    • Arroyo, V.1    Planas, R.2    Gaya, J.3    Deulofeu, R.4    Rimola, A.5    Pérez-Ayuso, R.M.6
  • 55
    • 0026642143 scopus 로고
    • Enhanced vaso-constrictor response of the isolated perfused cirrhotic rat liver to humoral vasoconstrictor substances found in portal venous blood
    • Grossman HJ, Grossman VL, Bhathal PS. Enhanced vaso-constrictor response of the isolated perfused cirrhotic rat liver to humoral vasoconstrictor substances found in portal venous blood. J Gastroenterol Hepatol 1992;7:283-7.
    • (1992) J Gastroenterol Hepatol , vol.7 , pp. 283-287
    • Grossman, H.J.1    Grossman, V.L.2    Bhathal, P.S.3
  • 56
    • 0036163806 scopus 로고    scopus 로고
    • 5-Lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: A possible role of cysteinyl-leukotrienes
    • Graupera M, García-Pagán JC, Titos E, Claria J, Massaguer A, Bosch J, et al. 5-lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: a possible role of cysteinyl-leukotrienes. Gastroenterology 2002;122:387-93.
    • (2002) Gastroenterology , vol.122 , pp. 387-393
    • Graupera, M.1    García-Pagán, J.C.2    Titos, E.3    Claria, J.4    Massaguer, A.5    Bosch, J.6
  • 59
    • 0031007570 scopus 로고    scopus 로고
    • Endothelin-induced vasoconstriction in isolated perfused liver preparations from normal and cirrhotic rats
    • Elliot AJ, Vo LT, Grossman VL, Bhathal PS, Grossman HJ. Endothelin-induced vasoconstriction in isolated perfused liver preparations from normal and cirrhotic rats. J Gastroenterol Hepatol 1997;12:314-8.
    • (1997) J Gastroenterol Hepatol , vol.12 , pp. 314-318
    • Elliot, A.J.1    Vo, L.T.2    Grossman, V.L.3    Bhathal, P.S.4    Grossman, H.J.5
  • 61
    • 0012236876 scopus 로고    scopus 로고
    • The effect of endothelin and its antagonist bosentan on hemodynamics and microvascular exchange in cirrhotic rat liver
    • Reichen J, Gerbes AL, Steiner MJ, Sagesser H, Clozel M. The effect of endothelin and its antagonist bosentan on hemodynamics and microvascular exchange in cirrhotic rat liver. J Hepatol 1998;28:1020-30.
    • (1998) J Hepatol , vol.28 , pp. 1020-1030
    • Reichen, J.1    Gerbes, A.L.2    Steiner, M.J.3    Sagesser, H.4    Clozel, M.5
  • 62
    • 0031752719 scopus 로고    scopus 로고
    • Beneficial hemodynamic effects of bosentan, a mixed ET(A) and ET(B) receptor antagonist, in portal hypertensive rats
    • Sogni P, Moreau R, Gomola A, Gadano A, Cailmail S, Calmus Y, et al. Beneficial hemodynamic effects of bosentan, a mixed ET(A) and ET(B) receptor antagonist, in portal hypertensive rats. Hepatology 1998;28:655-9.
    • (1998) Hepatology , vol.28 , pp. 655-659
    • Sogni, P.1    Moreau, R.2    Gomola, A.3    Gadano, A.4    Cailmail, S.5    Calmus, Y.6
  • 64
    • 0034120477 scopus 로고    scopus 로고
    • An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis
    • Cho JJ, Hocher B, Herbst H, Jia JD, Ruehl M, Hahn EG, et al. An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. Gastroenterology 2000;118:1169-78.
    • (2000) Gastroenterology , vol.118 , pp. 1169-1178
    • Cho, J.J.1    Hocher, B.2    Herbst, H.3    Jia, J.D.4    Ruehl, M.5    Hahn, E.G.6
  • 65
    • 0034958165 scopus 로고    scopus 로고
    • Endothelin-1 plays a major role in portal hypertension of biliary cirrhotic rats through endothelin receptor subtype B together with subtype A in vivo
    • Kojima H, Sakurai S, Kuriyama S, Yoshiji H, Imazu H, Uemura M, et al. Endothelin-1 plays a major role in portal hypertension of biliary cirrhotic rats through endothelin receptor subtype B together with subtype A in vivo. J Hepatol 2001;34:805-11.
    • (2001) J Hepatol , vol.34 , pp. 805-811
    • Kojima, H.1    Sakurai, S.2    Kuriyama, S.3    Yoshiji, H.4    Imazu, H.5    Uemura, M.6
  • 66
    • 0004452575 scopus 로고
    • The effects of synthetic vasopressin and angiotensin on the circulation in cirrhosis of the liver
    • Segel N, Bayley TJ, Paton A, et al. The effects of synthetic vasopressin and angiotensin on the circulation in cirrhosis of the liver. Clin Sci 1963;25:43-55.
    • (1963) Clin Sci , vol.25 , pp. 43-55
    • Segel, N.1    Bayley, T.J.2    Paton, A.3
  • 67
    • 0037772442 scopus 로고    scopus 로고
    • Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II
    • Bataller R, Sancho-Bru P, Ginés P, Lora JM, Al Garawi A, Solé M, et al. Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II. Gastroenterology 2003;125:117-25.
    • (2003) Gastroenterology , vol.125 , pp. 117-125
    • Bataller, R.1    Sancho-Bru, P.2    Ginés, P.3    Lora, J.M.4    Al Garawi, A.5    Solé, M.6
  • 68
    • 0023749667 scopus 로고
    • Peripheral arterial vasodilation hypothesis: A proposal for the initiation of renal sodium and water retention in cirrhosis
    • Schrier RW, Arroyo V, Bernardi M, Epstein M, Henriksen JH, Rodes J. Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis. Hepatology 1988;8:1151-7.
    • (1988) Hepatology , vol.8 , pp. 1151-1157
    • Schrier, R.W.1    Arroyo, V.2    Bernardi, M.3    Epstein, M.4    Henriksen, J.H.5    Rodes, J.6
  • 70
    • 0034898990 scopus 로고    scopus 로고
    • Hemodynamic effects of the angiotensin II receptor antagonist irbesartan in patients with cirrhosis and portal hypertension
    • Schepke M, Werner E, Biecker E, Schiedermaier P, Heller J, Neef M, et al. Hemodynamic effects of the angiotensin II receptor antagonist irbesartan in patients with cirrhosis and portal hypertension. Gastroenterology 2001;121:389-95.
    • (2001) Gastroenterology , vol.121 , pp. 389-395
    • Schepke, M.1    Werner, E.2    Biecker, E.3    Schiedermaier, P.4    Heller, J.5    Neef, M.6
  • 71
    • 0141595006 scopus 로고    scopus 로고
    • Inhibition of 5-lipoxygenase induces cell growth arrest and apoptosis in rat Kupffer cells: Implications for liver fibrosis
    • Titos E, Claria J, Planaguma A, López-Parra M, Villamor N, Parrizas M, et al. Inhibition of 5-lipoxygenase induces cell growth arrest and apoptosis in rat Kupffer cells: implications for liver fibrosis. FASEB J 2003;17:1745-7.
    • (2003) FASEB J , vol.17 , pp. 1745-1747
    • Titos, E.1    Claria, J.2    Planaguma, A.3    López-Parra, M.4    Villamor, N.5    Parrizas, M.6
  • 72
    • 0027978527 scopus 로고
    • Hemodynamic effects of alpha-adrenergic blockade with prazosin in cirrhotic patients with portal hypertension
    • Albillos A, Lledó JL, Banares R, Rossi I, Iborra J, Calleja JL, et al. Hemodynamic effects of alpha-adrenergic blockade with prazosin in cirrhotic patients with portal hypertension. Hepatology 1994;20:611-7.
    • (1994) Hepatology , vol.20 , pp. 611-617
    • Albillos, A.1    Lledó, J.L.2    Banares, R.3    Rossi, I.4    Iborra, J.5    Calleja, J.L.6
  • 73
    • 0029088488 scopus 로고
    • Continuous prazosin administration in cirrhotic patients: Effects on portal hemodynamics and on liver and renal function
    • Albillos A, Lledó JL, Rossi I, Pérez-Paramo M, Tabuenca MJ, Banares R, et al. Continuous prazosin administration in cirrhotic patients: effects on portal hemodynamics and on liver and renal function. Gastroenterology 1995;109:1257-65.
    • (1995) Gastroenterology , vol.109 , pp. 1257-1265
    • Albillos, A.1    Lledó, J.L.2    Rossi, I.3    Pérez-Paramo, M.4    Tabuenca, M.J.5    Banares, R.6
  • 75
    • 0034998782 scopus 로고    scopus 로고
    • In vivo angiogenesis in normal and portal hypertensive rats: Role of basic fibroblast growth factor and nitric oxide
    • Sieber CC, Sumanovski LT, Stumm M, Van der KM, Battegay E. In vivo angiogenesis in normal and portal hypertensive rats: role of basic fibroblast growth factor and nitric oxide. J Hepatol 2001;34:644-50.
    • (2001) J Hepatol , vol.34 , pp. 644-650
    • Sieber, C.C.1    Sumanovski, L.T.2    Stumm, M.3    Van Der, K.M.4    Battegay, E.5
  • 76
    • 0019522762 scopus 로고
    • Measurement of portal-systemic shunting in the rat by using gamma-labeled microspheres
    • Chojkier M, Groszmann RJ. Measurement of portal-systemic shunting in the rat by using gamma-labeled microspheres. Am J Physiol 1981;240:G371-G5.
    • (1981) Am J Physiol , vol.240
    • Chojkier, M.1    Groszmann, R.J.2
  • 77
    • 0026806784 scopus 로고
    • Pharmacology of portal-systemic collaterals in portal hypertensive rats: Role of endothelium
    • Mosca P, Lee FY, Kaumann AJ, Groszmann RJ. Pharmacology of portal-systemic collaterals in portal hypertensive rats: role of endothelium. Am J Physiol 1992;263:G544-G50.
    • (1992) Am J Physiol , vol.263
    • Mosca, P.1    Lee, F.Y.2    Kaumann, A.J.3    Groszmann, R.J.4
  • 78
    • 0032858372 scopus 로고    scopus 로고
    • Effects of vasopressin on portal-systemic collaterals in portal hypertensive rats: Role of nitric oxide and prostaglandin
    • Chan CC, Lee FY, Wang SS, Chang FY, Lin HC, Chu CJ, et al. Effects of vasopressin on portal-systemic collaterals in portal hypertensive rats: role of nitric oxide and prostaglandin. Hepatology 1999;30:630-5.
    • (1999) Hepatology , vol.30 , pp. 630-635
    • Chan, C.C.1    Lee, F.Y.2    Wang, S.S.3    Chang, F.Y.4    Lin, H.C.5    Chu, C.J.6
  • 79
    • 0035082815 scopus 로고    scopus 로고
    • Endothelin-1 induces vasoconstriction on portal-systemic collaterals of portal hypertensive rats
    • Chan CC, Wang SS, Lee FY, Chang FY, Lin HC, Chu CJ, et al. Endothelin-1 induces vasoconstriction on portal-systemic collaterals of portal hypertensive rats. Hepatology 2001;33:816-20.
    • (2001) Hepatology , vol.33 , pp. 816-820
    • Chan, C.C.1    Wang, S.S.2    Lee, F.Y.3    Chang, F.Y.4    Lin, H.C.5    Chu, C.J.6
  • 80
    • 0036169937 scopus 로고    scopus 로고
    • Effects of somatostatin and octreotide on portal-systemic collaterals in portal hypertensive rats
    • Huang HC, Lee FY, Chan CC, Chang FY, Wang SS, Lin HC, et al. Effects of somatostatin and octreotide on portal-systemic collaterals in portal hypertensive rats. J Hepatol 2002;36:163-8.
    • (2002) J Hepatol , vol.36 , pp. 163-168
    • Huang, H.C.1    Lee, F.Y.2    Chan, C.C.3    Chang, F.Y.4    Wang, S.S.5    Lin, H.C.6
  • 81
    • 0021927396 scopus 로고
    • Increased portal venous resistance hinders portal pressure reduction during the administration of beta-adrenergic blocking agents in a portal hypertensive model
    • Kroeger RJ, Groszmann RJ. Increased portal venous resistance hinders portal pressure reduction during the administration of beta-adrenergic blocking agents in a portal hypertensive model. Hepatology 1985;5:97-101.
    • (1985) Hepatology , vol.5 , pp. 97-101
    • Kroeger, R.J.1    Groszmann, R.J.2
  • 82
    • 0000601905 scopus 로고
    • The cardiac output at rest in Laennec cirrhosis
    • Kowalski HJ, Abelman WH. The cardiac output at rest in Laennec cirrhosis. J Clin Invest 1953;32:1025-33.
    • (1953) J Clin Invest , vol.32 , pp. 1025-1033
    • Kowalski, H.J.1    Abelman, W.H.2
  • 83
    • 0037904072 scopus 로고    scopus 로고
    • The way to a man's heart is through his liver
    • Reuben A. The way to a man's heart is through his liver. Hepatology 2003;37:1500-2.
    • (2003) Hepatology , vol.37 , pp. 1500-1502
    • Reuben, A.1
  • 84
    • 0020640009 scopus 로고
    • Hemodynamic changes in patients with portal venous obstruction
    • Lebrec D, Bataille C, Bercoff E, Valla D. Hemodynamic changes in patients with portal venous obstruction. Hepatology 1983;3:550-3.
    • (1983) Hepatology , vol.3 , pp. 550-553
    • Lebrec, D.1    Bataille, C.2    Bercoff, E.3    Valla, D.4
  • 85
    • 0029958327 scopus 로고    scopus 로고
    • Systemic and splanchnic hemodynamic changes in patients with hepatic schistosomiasis
    • Denie C, Vachiery F, Elman A, Soupison T, Gadano A, Moreau R, et al. Systemic and splanchnic hemodynamic changes in patients with hepatic schistosomiasis. Liver 1996;16:309-12.
    • (1996) Liver , vol.16 , pp. 309-312
    • Denie, C.1    Vachiery, F.2    Elman, A.3    Soupison, T.4    Gadano, A.5    Moreau, R.6
  • 86
    • 0020677377 scopus 로고
    • Hyperdynamic circulation in a portal hypertensive rat model: A primary factor for maintenance of chronic portal hypertension
    • Vorobioff J, Bredfeldt J, Groszmann RJ. Hyperdynamic circulation in a portal hypertensive rat model: a primary factor for maintenance of chronic portal hypertension. Am J Physiol 1983;244:G52-G6.
    • (1983) Am J Physiol , vol.244
    • Vorobioff, J.1    Bredfeldt, J.2    Groszmann, R.J.3
  • 87
    • 0021194801 scopus 로고
    • Increased blood flow through the portal system in cirrhotic rats
    • Vorobioff J, Bredfeldt JE, Grossmann RJ. Increased blood flow through the portal system in cirrhotic rats. Gastroenterology 1984;87:1120-3.
    • (1984) Gastroenterology , vol.87 , pp. 1120-1123
    • Vorobioff, J.1    Bredfeldt, J.E.2    Grossmann, R.J.3
  • 88
    • 0027938229 scopus 로고
    • Hyperdynamic circulation of liver disease 40 years later: Pathophysiology and clinical consequences
    • Grossmann RJ. Hyperdynamic circulation of liver disease 40 years later: pathophysiology and clinical consequences [editorial]. Hepatology 1994;20:1359-63.
    • (1994) Hepatology , vol.20 , pp. 1359-1363
    • Grossmann, R.J.1
  • 89
    • 0021522551 scopus 로고
    • Role of humoral factors in the intestinal hyperemia associated with chronic portal hypertension
    • Benoit JN, Barrowman JA, Harper SL, Kvietys PR, Granger DN. Role of humoral factors in the intestinal hyperemia associated with chronic portal hypertension. Am J Physiol 1984;247:G486-G93.
    • (1984) Am J Physiol , vol.247
    • Benoit, J.N.1    Barrowman, J.A.2    Harper, S.L.3    Kvietys, P.R.4    Granger, D.N.5
  • 90
    • 0023019353 scopus 로고
    • Splanchnic hemodynamics in chronic portal hypertension
    • Benoit JN, Granger DN. Splanchnic hemodynamics in chronic portal hypertension. Semin Liver Dis 1986;6:287-98.
    • (1986) Semin Liver Dis , vol.6 , pp. 287-298
    • Benoit, J.N.1    Granger, D.N.2
  • 91
    • 0028326756 scopus 로고
    • Impaired function of pancreatic islets from rats with portal hypertension resulting from cirrhosis and partial portal vein ligation
    • Gomis R, Fernández-Álvarez J, Pizcueta P, Fernández M, Casamitjana R, Bosch J, et al. Impaired function of pancreatic islets from rats with portal hypertension resulting from cirrhosis and partial portal vein ligation. Hepatology 1994;19:1257-61.
    • (1994) Hepatology , vol.19 , pp. 1257-1261
    • Gomis, R.1    Fernández-Álvarez, J.2    Pizcueta, P.3    Fernández, M.4    Casamitjana, R.5    Bosch, J.6
  • 93
    • 0023926293 scopus 로고
    • Effects of somatostatin on splanchnic hemodynamics and plasma glucagon in portal hypertensive rats
    • Kravetz D, Bosch J, Arderiu MT, Pizcueta MP, Casamitjana R, Rivera F, et al. Effects of somatostatin on splanchnic hemodynamics and plasma glucagon in portal hypertensive rats. Am J Physiol 1988;254:G322-G8.
    • (1988) Am J Physiol , vol.254
    • Kravetz, D.1    Bosch, J.2    Arderiu, M.T.3    Pizcueta, M.P.4    Casamitjana, R.5    Rivera, F.6
  • 94
    • 0025932420 scopus 로고
    • Glucagon hinders the effects of somatostatin on portal hypertension. A study in rats with partial portal vein ligation
    • Pizcueta MP, García-Pagán JC, Fernández M, Casamitjana R, Bosch J, Rodés J. Glucagon hinders the effects of somatostatin on portal hypertension. A study in rats with partial portal vein ligation. Gastroenterology 1991;101:1710-5.
    • (1991) Gastroenterology , vol.101 , pp. 1710-1715
    • Pizcueta, M.P.1    García-Pagán, J.C.2    Fernández, M.3    Casamitjana, R.4    Bosch, J.5    Rodés, J.6
  • 95
    • 0027932941 scopus 로고
    • Octreotide prevents postprandial splanchnic hyperemia in patients with portal hypertension
    • Albillos A, Rossi I, Iborra J, Lledó JL, Calleja JL, Barrios C, et al. Octreotide prevents postprandial splanchnic hyperemia in patients with portal hypertension. J Hepatol 1994;21:88-94.
    • (1994) J Hepatol , vol.21 , pp. 88-94
    • Albillos, A.1    Rossi, I.2    Iborra, J.3    Lledó, J.L.4    Calleja, J.L.5    Barrios, C.6
  • 96
    • 0036614743 scopus 로고    scopus 로고
    • Somatostatin and analogues in portal hypertension
    • Abraldes JG, Bosch J. Somatostatin and analogues in portal hypertension. Hepatology 2002;35:1305-12.
    • (2002) Hepatology , vol.35 , pp. 1305-1312
    • Abraldes, J.G.1    Bosch, J.2
  • 97
    • 0035127182 scopus 로고    scopus 로고
    • Octreotide potentiates PKC-dependent vasoconstrictors in portal-hypertensive and control rats
    • Wiest R, Tsai MH, Groszmann RJ. Octreotide potentiates PKC-dependent vasoconstrictors in portal-hypertensive and control rats. Gastroenterology 2001;120:975-83.
    • (2001) Gastroenterology , vol.120 , pp. 975-983
    • Wiest, R.1    Tsai, M.H.2    Groszmann, R.J.3
  • 98
    • 0025972590 scopus 로고
    • Hyperdynamic circulation in cirrhosis: A role for nitric oxide?
    • Vallance P, Moncada S. Hyperdynamic circulation in cirrhosis: a role for nitric oxide? Lancet 1991;337:776.
    • (1991) Lancet , vol.337 , pp. 776
    • Vallance, P.1    Moncada, S.2
  • 99
    • 0027438813 scopus 로고
    • Increased serum nitrite and nitrate levels in patients with cirrhosis: Relationship to endotoxemia
    • Guarner C, Soriano G, Tomás A, Bulbena O, Novella MT, Balanzo J, et al. Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to endotoxemia. Hepatology 1993;18:1139-43.
    • (1993) Hepatology , vol.18 , pp. 1139-1143
    • Guarner, C.1    Soriano, G.2    Tomás, A.3    Bulbena, O.4    Novella, M.T.5    Balanzo, J.6
  • 100
    • 0031036533 scopus 로고    scopus 로고
    • Hyperdynamic circulation in patients with cirrhosis: Direct measurement of nitric oxide levels in hepatic and portal veins
    • Battista S, Bar F, Mengozzi G, Zanon E, Grosso M, Molino G. Hyperdynamic circulation in patients with cirrhosis: direct measurement of nitric oxide levels in hepatic and portal veins. J Hepatol 1997;26:75-80.
    • (1997) J Hepatol , vol.26 , pp. 75-80
    • Battista, S.1    Bar, F.2    Mengozzi, G.3    Zanon, E.4    Grosso, M.5    Molino, G.6
  • 101
    • 0031737665 scopus 로고    scopus 로고
    • Enhanced relaease of nitric oxide in response to changes in flow and shear stress in the superior mesenteric arteries of portal hypertensive rats
    • Hori N, Wiest R. Enhanced relaease of nitric oxide in response to changes in flow and shear stress in the superior mesenteric arteries of portal hypertensive rats. Hepatology 1998;28:1467-73.
    • (1998) Hepatology , vol.28 , pp. 1467-1473
    • Hori, N.1    Wiest, R.2
  • 102
    • 0026749847 scopus 로고
    • Nitric oxide mediates hyporeactivity to vasopressors in mesenteric vessels of portal hypertensive rats
    • Sieber CC, Groszmann RJ. Nitric oxide mediates hyporeactivity to vasopressors in mesenteric vessels of portal hypertensive rats. Gastroenterology 1992;103:235-9.
    • (1992) Gastroenterology , vol.103 , pp. 235-239
    • Sieber, C.C.1    Groszmann, R.J.2
  • 104
    • 0026504731 scopus 로고
    • Effects of inhibiting nitric oxide biosynthesis on the systemic and splanchnic circulation of rats with portal hypertension
    • Pizcueta MP, Piqué JM, Bosch J, Whittle BJR, Moncada S. Effects of inhibiting nitric oxide biosynthesis on the systemic and splanchnic circulation of rats with portal hypertension. Br J Pharmacol 1992;105:105-84.
    • (1992) Br J Pharmacol , vol.105 , pp. 105-184
    • Pizcueta, M.P.1    Piqué, J.M.2    Bosch, J.3    Whittle, B.J.R.4    Moncada, S.5
  • 105
    • 0027431064 scopus 로고
    • Administration of N omega-nitro-L-arginine ameliorates portal-systemic shunting in portal-hypertensive rats
    • Lee FY, Colombato LA, Albillos A, Groszmann RJ. Administration of N omega-nitro-L-arginine ameliorates portal-systemic shunting in portal-hypertensive rats. Gastroenterology 1993;105:1464-70.
    • (1993) Gastroenterology , vol.105 , pp. 1464-1470
    • Lee, F.Y.1    Colombato, L.A.2    Albillos, A.3    Groszmann, R.J.4
  • 106
    • 0028601320 scopus 로고
    • Effects of continued nitric oxide inhibition on the development of the portal hypertensive syndrome following portal vein stenosis in the rat
    • García-Pagán JC, Fernández M, Bernadich C, Pizcueta P, Piqué JM, Bosch J, et al. Effects of continued nitric oxide inhibition on the development of the portal hypertensive syndrome following portal vein stenosis in the rat. Am J Physiol 1994;30:984-90.
    • (1994) Am J Physiol , vol.30 , pp. 984-990
    • García-Pagán, J.C.1    Fernández, M.2    Bernadich, C.3    Pizcueta, P.4    Piqué, J.M.5    Bosch, J.6
  • 109
    • 0028925856 scopus 로고
    • Evidence against a role for inducible nitric oxide synthase in the hyperdynamic circulation of portal-hypertensive rats
    • Fernández M, García-Pagán JC, Casadevall M, Bernadich C, Piera C, Whittle BJ, et al. Evidence against a role for inducible nitric oxide synthase in the hyperdynamic circulation of portal-hypertensive rats. Gastroenterology 1995;108:1487-95.
    • (1995) Gastroenterology , vol.108 , pp. 1487-1495
    • Fernández, M.1    García-Pagán, J.C.2    Casadevall, M.3    Bernadich, C.4    Piera, C.5    Whittle, B.J.6
  • 110
    • 0029965368 scopus 로고    scopus 로고
    • Upregulation of endothelial constitutive NOS: A major role in the increased NO production in cirrhotic rats
    • Martin PY, Xu DL, Niederberger M, Weigert A, Tsai P, St. John J, et al. Upregulation of endothelial constitutive NOS: a major role in the increased NO production in cirrhotic rats. Am J Physiol 1996;270:F494-F9.
    • (1996) Am J Physiol , vol.270
    • Martin, P.Y.1    Xu, D.L.2    Niederberger, M.3    Weigert, A.4    Tsai, P.5    St. John, J.6
  • 111
    • 0032696338 scopus 로고    scopus 로고
    • Bacterial translocation in cirrhotic rats stimulates eNOS-derived NO production and impairs mesenteric vascular contractility
    • Wiest R, Das S, Cadelina G, García-Tsao G, Milstien S, Groszmann RJ. Bacterial translocation in cirrhotic rats stimulates eNOS-derived NO production and impairs mesenteric vascular contractility. J Clin Invest 1999;104:1223-33.
    • (1999) J Clin Invest , vol.104 , pp. 1223-1233
    • Wiest, R.1    Das, S.2    Cadelina, G.3    García-Tsao, G.4    Milstien, S.5    Groszmann, R.J.6
  • 112
    • 0032883956 scopus 로고    scopus 로고
    • Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension
    • Shah V, Wiest R, García-Cardena G, Cadelina G, Groszmann RJ, Sessa WC. Hsp90 regulation of endothelial nitric oxide synthase contributes to vascular control in portal hypertension. Am J Physiol 1999;277:G463-G8.
    • (1999) Am J Physiol , vol.277
    • Shah, V.1    Wiest, R.2    García-Cardena, G.3    Cadelina, G.4    Groszmann, R.J.5    Sessa, W.C.6
  • 113
    • 0032938259 scopus 로고    scopus 로고
    • NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats
    • Wiest R, Shah V, Sessa WC, Groszmann RJ. NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats. Am J Physiol 1999;276:G1043-G51.
    • (1999) Am J Physiol , vol.276
    • Wiest, R.1    Shah, V.2    Sessa, W.C.3    Groszmann, R.J.4
  • 114
    • 0242490247 scopus 로고    scopus 로고
    • Mesenteric vasoconstriction triggers nitric oxide overproduction in the superior mesenteric artery of portal hypertensive rats
    • Tsai MH, Iwakiri Y, Cadelina G, Sessa WC, Groszmann RJ. Mesenteric vasoconstriction triggers nitric oxide overproduction in the superior mesenteric artery of portal hypertensive rats. Gastroenterology 2003;125:1452-61.
    • (2003) Gastroenterology , vol.125 , pp. 1452-1461
    • Tsai, M.H.1    Iwakiri, Y.2    Cadelina, G.3    Sessa, W.C.4    Groszmann, R.J.5
  • 115
    • 0037219393 scopus 로고    scopus 로고
    • Increased lipopolysaccharide binding protein in cirrhotic patients with marked immune and hemodynamic derangement
    • Albillos A, De la Hera A, González M, Moya JL, Calleja JL, Monserrat J, et al. Increased lipopolysaccharide binding protein in cirrhotic patients with marked immune and hemodynamic derangement. Hepatology 2003;37:208-17.
    • (2003) Hepatology , vol.37 , pp. 208-217
    • Albillos, A.1    De La Hera, A.2    González, M.3    Moya, J.L.4    Calleja, J.L.5    Monserrat, J.6
  • 116
    • 0030739764 scopus 로고    scopus 로고
    • Circulatory effects of graded diversion of portal blood flow to the systemic circulation in rats: Role of nitric oxide
    • Bernadich C, Bandi JC, Piera C, Bosch J, Rodés J. Circulatory effects of graded diversion of portal blood flow to the systemic circulation in rats: role of nitric oxide. Hepatology 1997;26:262-7.
    • (1997) Hepatology , vol.26 , pp. 262-267
    • Bernadich, C.1    Bandi, J.C.2    Piera, C.3    Bosch, J.4    Rodés, J.5
  • 117
    • 0344117716 scopus 로고    scopus 로고
    • Hyperkinetic circulation and decreased sensitivity to vasoconstrictors following portacaval shunt in the rat. Effects of chronic nitric oxide inhibition
    • Bandi JC, Fernández M, Bernadich C, De Lacy AM, García-Pagán JC, Bosch J, et al. Hyperkinetic circulation and decreased sensitivity to vasoconstrictors following portacaval shunt in the rat. Effects of chronic nitric oxide inhibition. J Hepatol 1999;31:719-24.
    • (1999) J Hepatol , vol.31 , pp. 719-724
    • Bandi, J.C.1    Fernández, M.2    Bernadich, C.3    De Lacy, A.M.4    García-Pagán, J.C.5    Bosch, J.6
  • 118
    • 0034957736 scopus 로고    scopus 로고
    • Hemodynamic, renal, and endocrine effects of acute inhibition of nitric oxide synthase in compensated cirrhosis
    • La Villa G, Barletta G, Pantaleo P, Del Bene R, Vizzutti F, Vecchiarino S, et al. Hemodynamic, renal, and endocrine effects of acute inhibition of nitric oxide synthase in compensated cirrhosis. Hepatology 2001;34:19-27.
    • (2001) Hepatology , vol.34 , pp. 19-27
    • La Villa, G.1    Barletta, G.2    Pantaleo, P.3    Del Bene, R.4    Vizzutti, F.5    Vecchiarino, S.6
  • 119
    • 0029080383 scopus 로고
    • The effect of nitric oxide synthase inhibition on portal pressure and azygos blood flow in patients with cirrhosis
    • Forrest EH, Jones AL, Dillon JF, Walker J, Hayes PC. The effect of nitric oxide synthase inhibition on portal pressure and azygos blood flow in patients with cirrhosis. J Hepatol 1995;23:254-8.
    • (1995) J Hepatol , vol.23 , pp. 254-258
    • Forrest, E.H.1    Jones, A.L.2    Dillon, J.F.3    Walker, J.4    Hayes, P.C.5
  • 120
    • 0024523451 scopus 로고
    • Role of prostacyclin in the splanchnic hyperemia contributing to portal hypertension
    • Sitzmann JV, Bulkley GB. Role of prostacyclin in the splanchnic hyperemia contributing to portal hypertension. Ann Surg 1989;209:322-7.
    • (1989) Ann Surg , vol.209 , pp. 322-327
    • Sitzmann, J.V.1    Bulkley, G.B.2
  • 121
    • 0026502391 scopus 로고
    • Systemic prostacyclin in cirrhotic patients. Relationship with portal hypertension and changes after intestinal decontamination
    • Guarner C, Soriano G, Such J, Teixidó M, Ramis I, Bulbena O, et al. Systemic prostacyclin in cirrhotic patients. Relationship with portal hypertension and changes after intestinal decontamination [véanse comentarios]. Gastroenterology 1992;102:303-9.
    • (1992) Gastroenterology , vol.102 , pp. 303-309
    • Guarner, C.1    Soriano, G.2    Such, J.3    Teixidó, M.4    Ramis, I.5    Bulbena, O.6
  • 123
    • 0029920878 scopus 로고    scopus 로고
    • Acute and chronic cyclooxygenase blockade in portal hypertensive rats. Influence on nitric oxide biosynthesis
    • Fernández M, García-Pagán JC, Casadevall M, Mourelle M, Pique JM, Bosch J, et al. Acute and chronic cyclooxygenase blockade in portal hypertensive rats. Influence on nitric oxide biosynthesis. Gastroenterology 1996;110:1529-35.
    • (1996) Gastroenterology , vol.110 , pp. 1529-1535
    • Fernández, M.1    García-Pagán, J.C.2    Casadevall, M.3    Mourelle, M.4    Pique, J.M.5    Bosch, J.6
  • 124
    • 0031961750 scopus 로고    scopus 로고
    • Enhanced cyclooxygenase-1 expression within the superior mesenteric artery of portal hypertensive rats: Role in the hyperdynamic circulation
    • Hou MC, Cahill PA, Zhang S, Wang YN, Hendrickson RJ, Redmond EM, et al. Enhanced cyclooxygenase-1 expression within the superior mesenteric artery of portal hypertensive rats: role in the hyperdynamic circulation. Hepatology 1998;27:20-7.
    • (1998) Hepatology , vol.27 , pp. 20-27
    • Hou, M.C.1    Cahill, P.A.2    Zhang, S.3    Wang, Y.N.4    Hendrickson, R.J.5    Redmond, E.M.6
  • 125
    • 0021994982 scopus 로고
    • Effects of prostaglandin inhibition on systemic and hepatic hemodynamics in patients with cirrhosis of the liver
    • Bruix J, Bosch J, Kravetz D, Mastai R, Rodés J. Effects of prostaglandin inhibition on systemic and hepatic hemodynamics in patients with cirrhosis of the liver. Gastroenterology 1985;88:430-5.
    • (1985) Gastroenterology , vol.88 , pp. 430-435
    • Bruix, J.1    Bosch, J.2    Kravetz, D.3    Mastai, R.4    Rodés, J.5
  • 126
    • 0032991092 scopus 로고    scopus 로고
    • Increased heme oxygenase-1 gene expression in liver cells and splanchnic organs from portal hypertensive rats
    • Fernández M, Bonkovsky HL. Increased heme oxygenase-1 gene expression in liver cells and splanchnic organs from portal hypertensive rats. Hepatology 1999;29:1672-9.
    • (1999) Hepatology , vol.29 , pp. 1672-1679
    • Fernández, M.1    Bonkovsky, H.L.2
  • 127
    • 0034948624 scopus 로고    scopus 로고
    • Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: Role in modulating mesenteric vascular reactivity
    • Fernández M, Lambrecht RW, Bonkovsky HL. Increased heme oxygenase activity in splanchnic organs from portal hypertensive rats: role in modulating mesenteric vascular reactivity. J Hepatol 2001;34:812-7.
    • (2001) J Hepatol , vol.34 , pp. 812-817
    • Fernández, M.1    Lambrecht, R.W.2    Bonkovsky, H.L.3
  • 128
    • 0034928628 scopus 로고    scopus 로고
    • Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis
    • Bàtkai S, Jarai Z, Wagner JA, Goparaju SK, Varga K, Liu J, et al. Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nat Med 2001;7:827-32.
    • (2001) Nat Med , vol.7 , pp. 827-832
    • Bàtkai, S.1    Jarai, Z.2    Wagner, J.A.3    Goparaju, S.K.4    Varga, K.5    Liu, J.6
  • 129
    • 0036142225 scopus 로고    scopus 로고
    • Endogenous cannabinoids: A new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat
    • Ros J, Claria J, To-Figueras J, Planaguma A, Cejudo-Martón P, Fernández-Varo G, et al. Endogenous cannabinoids: a new system involved in the homeostasis of arterial pressure in experimental cirrhosis in the rat. Gastroenterology 2002;122:85-93.
    • (2002) Gastroenterology , vol.122 , pp. 85-93
    • Ros, J.1    Claria, J.2    To-Figueras, J.3    Planaguma, A.4    Cejudo-Martón, P.5    Fernández-Varo, G.6
  • 130
    • 0031823187 scopus 로고    scopus 로고
    • Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension
    • Varga K, Wagner JA, Bridgen DT, Kunos G. Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. FASEB J 1998;12:1035-44.
    • (1998) FASEB J , vol.12 , pp. 1035-1044
    • Varga, K.1    Wagner, J.A.2    Bridgen, D.T.3    Kunos, G.4
  • 132
    • 0025159776 scopus 로고
    • Na restriction blunts expansion of plasma volume and ameliorates hyperdynamic circulation in portal hypertension
    • Genecin P, Polio J, Groszmann RJ. Na restriction blunts expansion of plasma volume and ameliorates hyperdynamic circulation in portal hypertension. Am J Physiol 1990;259:G498-G503.
    • (1990) Am J Physiol , vol.259
    • Genecin, P.1    Polio, J.2    Groszmann, R.J.3
  • 133
    • 0028212762 scopus 로고
    • Effects of low-sodium diet and spironolactone on portal pressure in patients with compensated cirrhosis
    • García-Pagán JC, Salmerón JM, Feu F, Luca A, Ginés P, Pizcueta P, et al. Effects of low-sodium diet and spironolactone on portal pressure in patients with compensated cirrhosis. Hepatology 1994;19:1095-9.
    • (1994) Hepatology , vol.19 , pp. 1095-1099
    • García-Pagán, J.C.1    Salmerón, J.M.2    Feu, F.3    Luca, A.4    Ginés, P.5    Pizcueta, P.6
  • 134
    • 0026583936 scopus 로고
    • Vasodilatation and sodium retention in prehepatic portal hypertension
    • Albillos A, Colombato LA, Groszmann RJ. Vasodilatation and sodium retention in prehepatic portal hypertension [véanse comentarios]. Gastroenterology 1992;102:931-5.
    • (1992) Gastroenterology , vol.102 , pp. 931-935
    • Albillos, A.1    Colombato, L.A.2    Groszmann, R.J.3
  • 135
    • 0030044539 scopus 로고    scopus 로고
    • The role of central blood volume in the development of sodium retention in portal hypertensive rats
    • Colombato LA, Albillos A, Groszmann RJ. The role of central blood volume in the development of sodium retention in portal hypertensive rats. Gastroenterology 1996;110:193-8.
    • (1996) Gastroenterology , vol.110 , pp. 193-198
    • Colombato, L.A.1    Albillos, A.2    Groszmann, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.