A single amino acid change in gp41 is linked to the macrophage-only replication phenotype of a molecular clone of simian immunodeficiency virus derived from the brain of a macaque with neuropathogenic infection

Virology

Volumn 325, Issue 2, 2004, Pages 297-307

  Glenn, Amanda A ^a   Novembre, Francis J ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Macrophage; Molecular clone; Neuropathogenesis; Replication; SIV; Tropism

Indexed keywords

GLYCOPROTEIN GP 41; MUTANT PROTEIN; PROLINE; SERINE; VIRUS ENVELOPE PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL DIVISION; CONTROLLED STUDY; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE DEFICIENCY; MACACA; MACROPHAGE; MOLECULAR CLONING; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL GENETICS; VIRUS CELL INTERACTION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; BRAIN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DNA, VIRAL; HUMANS; MACACA NEMESTRINA; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; RETROVIRIDAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIRULENCE; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; MACACA; MACACA NEMESTRINA; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; SUS SCROFA;

EID: 3142645024     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2004.04.048     Document Type: Article

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