Pathogenesis of simian immunodeficiency virus encephalitis: Viral determinants of neurovirulence

Journal of Virology

Volumn 71, Issue 8, 1997, Pages 6055-6060

  Mankowski, J L ^a   Flaherty, M T ^a   Spelman, J P ^a   Hauer, D A ^a   Didier, P J ^b   Martin Amedee, A ^b   Murphey Corb, M ^b   Kirstein, L M ^c   Munoz A ^c   Clements, J E ^a   Zink, M C ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TULANE NATIONAL PRIMATE RESEARCH CENTER   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENVELOPE GENE; MACACA; MACROPHAGE; MONKEY DISEASE; NEUROTROPISM; NONHUMAN; PRIORITY JOURNAL; VIRUS ENCEPHALITIS; VIRUS INFECTIVITY;

EID: 0030785798     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.8.6055-6060.1997     Document Type: Article

References (25)

1. Anderson, M. G., D. Hauer, D. P. Sharma, S. V. Joag, O. Narayan, M. C. Zink, and J. E. Clements. 1993. Analysis of envelope changes acquired by SIVmac239 during neuroadaption in rhesus macaques. Virology 195:616-626.
2. Brinkmann, R., A. Schwinn, O. Narayan, M. C. Zink, H. W. Kreth, W. Roggendorf, R. Dorries, S. Schwender, H. Imrich, and V. Ter Meulen. 1992. Human immunodeficiency virus infection in microglia: correlation between cells infected in the brain and cells cultured from infectious brain tissue. Ann. Neurol. 31:361-365.
3. Cserr, H. F. 1988. Role of secretion and bulk flow of brain interstitial fluid in brain volume regulation. Ann. N. Y. Acad. Sci. 529:9-20.
4. Desrosiers, R. C., A. Hansen-Moosa, K. Mori, D. P. Bouvier, N. W. King, and D. J. Ringler. 1991. Macrophage-tropic variants of SIV are associated with specific AIDS-related lesions but are not essential for the development of AIDS. Am. J. Pathol. 139:29-35.
5. Flaherty, M., D. A. Hauer, J. L. Mankowski, M. C. Zink, and J. E. Clements. 1997. Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virus. J. Virol. 71:5790-5798.
6. Goodenow, M., T. Huet, W. Saurin, S. Kwok, J. Sninsky, and S. Wain-Hobson. 1989. HIV-1 isolates are rapidly evolving quasispecies: evidence for viral mixtures and preferred nucleotide substitutions. J. Acquired Immune Defic. Syndr. 2:344-352.
7. Irani, D. N., and D. E. Griffin. 1996. Regulation of lymphocyte homing into the brain during viral encephalitis at various stages of infection. J. Immunol. 156:3850-3857.
8. Kodama, T., K. Mori, T. Kawahara, D. J. Ringler, and R. C. Desrosiers. 1993. Analysis of simian immunodeficiency virus sequence variation in tissues of rhesus macaques with simian AIDS. J. Virol. 67:6522-6534.
9. Koyanagi, Y., S. Miles, R. T. Mitsuyasu, J. E. Merrill, H. V. Vinters, and I. S. Chen. 1987. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 236:819-822.
10. Lackner, A. A., M. O. Smith, R. J. Munn, D. J. Martfeld, M. B. Gardner, P. A. Marx, and S. Dandekar. 1991. Localization of simian immunodeficiency virus in the central nervous system of rhesus monkeys. Am. J. Pathol. 139:609-621.
11. Mankowski, J. L., J. P. Spelman, H. G. Ressetar, J. D. Strandberg, J. Laterra, D. L. Carter, J. E. Clements, and M. C. Zink. 1994. Neurovirulent simian immunodeficiency virus replicates productively in endothelial cells of the central nervous system in vivo and in vitro. J. Virol. 68:8202-8208.
12. Martin, L. N., M. Murphey-Corb, M. Soike, B. Davidson-Fairburn, and G. B. Baskin. 1993. Effects of initiation of 3′-azido,3′-deoxythimidine (zidovudine) treatment at different times after infection of rhesus monkeys with simian immunodeficiency virus. J. Infect. Dis. 168:825-835.
13. McArthur, J. C., D. R. Hoover, H. Bacellar, E. N. Miller, B. A. Cohen, J. T. Becker, N. M. H. Graham, J. H. McArthur, O. A. Selnes, L. P. Jacobson, B. R. Visscher, M. Concha, and A. Saah. 1993. Dementia in AIDS patients: incidence and risk factors. Neurology 43:2245-2252.
14. McArthur, J. C., O. A. Selnes, J. D. Glass, D. R. Hoover, and H. Bacellar. 1994. HIV dementia. Incidence and risk factors, p. 251-272. In R. W. Price and S. W. Perry (ed.), HIV, AIDS and the brain. Raven Press, New York, N.Y.
15. Mori, K., D. J. Ringler, T. Kodama, and R. C. Desrosiers. 1992. Complex determinants of macrophage tropism in env of simian immunodeficiency virus. J. Virol. 66:2067-2075.
16. Murray, E. A., D. M. Rausch, J. Lendvay, L. R. Sharer, and L. E. Eiden. 1992. Cognitive and motor impairments associated with SIV infection in rhesus monkeys. Science 255:1246-1249.
17. Price, R. W. 1996. Neurological complications of HIV infection. Lancet 348:445-452.
18. Price, R. W., B. Brew, J. Sidtis, M. Rosenblum, A. C. Scheck, and P. Cleary. 1988. The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex. Science 239:586-592.
19. Ringler, D. J., R. D. Hunt, R. C. Desrosiers, M. D. Daniel, L. V. Chalifoux, and N. W. King. 1988. Simian immunodeficiency virus-induced meningoencephalitis: natural history and retrospective study. Ann. Neurol. 23(Suppl.): S101-S107.
20. Sharer, L. R., G. B. Baskin, E. S. Cho, M. Murphey Corb, B. M. Blumberg, and L. G. Epstein. 1988. Comparison of simian immunodeficiency virus and human immunodeficiency virus encephalitides in the immature host. Ann. Neurol. 23(Suppl.):S108-S112.
21. Sharer, L. R., J. Michaels, M. Murphey-Corb, F.-S. Hu, D. J. Kuebler, L. N. Martin, and G. B. Baskin. 1991. Serial pathogenesis study of SIV brain infection. J. Med. Primatol. 20:211-217.
22. Sharma, D. P., M. C. Zink, M. Anderson, R. Adams, J. E. Clements, S. V. Joag, and O. Narayan. 1992. Derivation of neurotropic simian immunodeficiency virus from exclusively lymphocytetropic parental virus: pathogenesis of infection in macaques. J. Virol. 66:3550-3556.
23. Wiley, C. A., R. D. Schrier, J. A. Nelson, P. W. Lampert, and M. B. A. Oldstone. 1986. Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc. Natl. Acad. Sci. USA 83:7089-7093.
24. Zink, M. C., A. Amedee Martin, J. L. Mankowski, L. Craig, A. Munoz, J. P. Spelman, P. Didier, M. Murphey-Corb, D. L. Carter, and J. E. Clements. SIV encephalitis: selection of neurovirulent strains of virus by the CNS. Am. J. Pathol., in press.
25. Zink, M. C., J. A. Yager, and J. D. Myers. 1990. Pathogenesis of caprine arthritis encephalitis virus. Cellular localization of viral transcripts in tissues of infected goats. Am. J. Pathol. 136:843-854.