Oxidative DNA damage by a metabolite of carcinogenic 1-nitropyrene

Biochemical and Biophysical Research Communications

Volumn 280, Issue 1, 2001, Pages 48-52

  Ohnishi, Shiho ^a   Murata, Mariko ^a   Fukuhara, Kiyoshi ^b   Miyata, Naoki ^b   Kawanishi, Shosuke ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Copper; DNA damage; Hydrogen peroxide; Nitropyrene; Nitrosopyrene

Indexed keywords

1 NITROPYRENE; 1 NITROSOPYRENE; 8 HYDROXYDEOXYGUANOSINE; CATALASE; CHELATING AGENT; COPPER; DNA; HYDROGEN PEROXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE;

ARTICLE; CARCINOGENESIS; DNA DAMAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

EID: 0034805347     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.4095     Document Type: Article

References (29)

1. Diesel and gasoline engine exhausts and some nitroarenes
2. Determination of nitrated polynuclear aromatic hydrocarbons chromatography with nitrogen selective detection
3. Metabolism of nitroaromatic compounds
4. Metabolism and DNA binding of 1-nitropyrene and 1-nitrosopyrene in newborn mice
5. DNA adduct formation and mutation induction by nitropyrenes in Salmonella and Chinese hamster ovary cells: Relationships with nitroreduction and acetylation
6. An examination of the weak mutagenic response of 1-nitropyrene in Chinese hamster ovary cells
7. Formation of DNA adducts in vitro and in Salmonella typhimurium upon metabolic reduction of the environmental mutagen 1-nitropyrene
8. The induction of DNA adducts in mammalian cells exposed to 1-nitropyrene and its nitro-reduced derivatives
9. Cytotoxicity, cellular transformation and DNA adducts in normal human diploid fibroblasts exposed to 1-nitrosopyrene, a reduced derivative of the environmental contaminant, 1-nitropyrene
10. Formation of DNA adducts and oxidative DNA damage in rats treated with 1,6-dinitropyrene
11. Comparative tumorigenicity of 1-nitropyrene, 1-nitrosopyrene, and 1-aminopyrene administered by gavage to Sprague-Dawley rats
12. Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue
13. Superoxide formation and DNA damage induced by a fragrant furanone in the presence of copper(II)
14. Mechansim of DNA cleavage induced by sodium chromate(VI) in the presence of hydrogen peroxide
15. Oxidative DNA damage induced by an N-hydroxy metabolite of carcinogenic 4-dimethylaminoazobenzene
16. Sequencing end-labeled DNA with base-specific chemical cleavages
17. 8-Hydroxydeoxyguanosine formation at the 5′ site of 5′-GG-3′ sequences in double-stranded DNA by UV radiation with reboflavin
18. Oxygen species in paraquat toxicity: The crypto-OH radical
19. DNA degradation by the mixture of copper and catechol is caused by DNA-copper-hydroperoxo complexes, probably DNA-Cu(I)OOH
20. Hydroxyl free radical is not the main active species in site-specific DNA damage induced by copper(II) ion and hydrogen peroxide
21. Mapping of copper/hydrogen peroxide-induced DNA damage at nucleotide resolution in human genomic DNA by lgiation-mediated polymerase chain reaction
22. The stimulus-secretion coupling of glucose-induced insulin release
23. Ferritin stimulation of hydroxyl radical production by rat liver nuclei
24. Nonenzymatic reduction of nitro derivative of a heterocyclic amine IQ by NADH and Cu(II) leads to oxidative DNA damage
25. Metal-mediated DNA damage induced by diabetogenic alloxan in the presence of NADH
26. Kinds and spectrum of mutations induced by 1-nitrosopyrene adducts during plasmid replication in human cells
27. Aerobic and anaerobic reduction of nitrated pyrenes in vitro