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Volumn 316, Issue 2, 2006, Pages 636-646

Genetic variants of the human dipeptide transporter PEPT1

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE TRANSPORTER 1;

EID: 31144449787     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.094615     Document Type: Article
Times cited : (47)

References (32)
  • 2
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 3
    • 0942279631 scopus 로고    scopus 로고
    • Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2
    • Bravo SA, Nielsen CU, Amstrup J, Frokjaer S, and Brodin B (2004) Epidermal growth factor decreases PEPT2 transport capacity and expression in the rat kidney proximal tubule cell line SKPT0193 cl.2. Am J Physiol 286:F385-F393.
    • (2004) Am J Physiol , vol.286
    • Bravo, S.A.1    Nielsen, C.U.2    Amstrup, J.3    Frokjaer, S.4    Brodin, B.5
  • 5
    • 0034674271 scopus 로고    scopus 로고
    • Functional roles of histidine and tyrosine residues in the H(+)-peptide transporter PepT1
    • Chen XZ, Steel A, and Hediger MA (2000) Functional roles of histidine and tyrosine residues in the H()-peptide transporter PepT1. Biochem Biophys Res Commun 272:726-730.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 726-730
    • Chen, X.Z.1    Steel, A.2    Hediger, M.A.3
  • 6
    • 0030464177 scopus 로고    scopus 로고
    • Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells
    • Covitz KM, Amidon GL, and SadeeW(1996) Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells. Pharm Res (NY) 13:1631-1634.
    • (1996) Pharm Res (NY) , vol.13 , pp. 1631-1634
    • Covitz, K.M.1    Amidon, G.L.2    Sadee, W.3
  • 7
    • 27744463332 scopus 로고    scopus 로고
    • Pharmacogenetics/genomics and personalized medicine
    • Dai Z and Sadee W (2005) Pharmacogenetics/genomics and personalized medicine. Hum Mol Genet 14 (Spec. No. 2):R207-R14.
    • (2005) Hum Mol Genet , vol.14 , Issue.SPEC. NO. 2
    • Dai, Z.1    Sadee, W.2
  • 8
    • 0032495995 scopus 로고    scopus 로고
    • Identification of a potential substrate binding domain in the mammalian peptide transporters PEPT1 and PEPT2 using PEPT1-PEPT2 and PEPT2-PEPT1 chimeras
    • Fei YJ, Liu JC, Fujita T, Liang R, Ganapathy V, and Leibach FH (1998) Identification of a potential substrate binding domain in the mammalian peptide transporters PEPT1 and PEPT2 using PEPT1-PEPT2 and PEPT2-PEPT1 chimeras. Biochem Biophys Res Commun 246:39-44.
    • (1998) Biochem Biophys Res Commun , vol.246 , pp. 39-44
    • Fei, Y.J.1    Liu, J.C.2    Fujita, T.3    Liang, R.4    Ganapathy, V.5    Leibach, F.H.6
  • 9
    • 0031037730 scopus 로고    scopus 로고
    • Identification of the histidyl residue obligatory for the catalytic activity of the human H/peptide cotransporters PEPT1 and PEPT2
    • Fei YJ, Liu W, Prasad PD, Kekuda R, Oblak TG, Ganapathy V, and Leibach FH (1997) Identification of the histidyl residue obligatory for the catalytic activity of the human H/peptide cotransporters PEPT1 and PEPT2. Biochemistry 36:452-460.
    • (1997) Biochemistry , vol.36 , pp. 452-460
    • Fei, Y.J.1    Liu, W.2    Prasad, P.D.3    Kekuda, R.4    Oblak, T.G.5    Ganapathy, V.6    Leibach, F.H.7
  • 10
    • 0028826927 scopus 로고
    • Differential recognition of beta-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2
    • Ganapathy ME, Brandsch M, Prasad PD, Ganapathy V, and Leibach FH (1995) Differential recognition of beta-lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2. J Biol Chem 270:25672-25677.
    • (1995) J Biol Chem , vol.270 , pp. 25672-25677
    • Ganapathy, M.E.1    Brandsch, M.2    Prasad, P.D.3    Ganapathy, V.4    Leibach, F.H.5
  • 12
    • 0031662109 scopus 로고    scopus 로고
    • 5′-Amino acid esters of antiviral nucleosides, acyclovir and AZT are absorbed by the intestinal PEPT1 peptide transporter
    • Han H, de Vrueh RL, Rhie JK, Covitz KM, Smith PL, Lee CP, Oh DM, Sadee W, and Amidon GL (1998) 5′-Amino acid esters of antiviral nucleosides, acyclovir and AZT are absorbed by the intestinal PEPT1 peptide transporter. Pharm Res (NY) 15:1154-1159.
    • (1998) Pharm Res (NY) , vol.15 , pp. 1154-1159
    • Han, H.1    De Vrueh, R.L.2    Rhie, J.K.3    Covitz, K.M.4    Smith, P.L.5    Lee, C.P.6    Oh, D.M.7    Sadee, W.8    Amidon, G.L.9
  • 14
    • 15344340688 scopus 로고    scopus 로고
    • Polymorphisms affecting gene regulation and mRNA processing: Broad implications for pharmacogenetics
    • Johnson AD, Wang D, and Sadee W (2005) Polymorphisms affecting gene regulation and mRNA processing: broad implications for pharmacogenetics. Pharmacol Ther 106:19-38.
    • (2005) Pharmacol Ther , vol.106 , pp. 19-38
    • Johnson, A.D.1    Wang, D.2    Sadee, W.3
  • 15
    • 0037639273 scopus 로고    scopus 로고
    • Optimal absorptive transport of the dipeptide glycylsarcosine is dependent on functional Na/H exchange activity
    • Kennedy DJ, Leibach FH, Ganapathy V, and Thwaites DT (2002) Optimal absorptive transport of the dipeptide glycylsarcosine is dependent on functional Na/H exchange activity. Pflueg Arch Eur J Physiol 445:139-146.
    • (2002) Pflueg Arch Eur J Physiol , vol.445 , pp. 139-146
    • Kennedy, D.J.1    Leibach, F.H.2    Ganapathy, V.3    Thwaites, D.T.4
  • 16
    • 0347064342 scopus 로고    scopus 로고
    • Analysis of transmembrane segment 7 of the dipeptide transporter hPepT1 by cysteine-scanning mutagenesis
    • Kulkarni AA, Haworth IS, Uchiyama T, and Lee VH (2003) Analysis of transmembrane segment 7 of the dipeptide transporter hPepT1 by cysteine-scanning mutagenesis. J Biol Chem 278:51833-51840.
    • (2003) J Biol Chem , vol.278 , pp. 51833-51840
    • Kulkarni, A.A.1    Haworth, I.S.2    Uchiyama, T.3    Lee, V.H.4
  • 19
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, and Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215.
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 20
    • 0036337915 scopus 로고    scopus 로고
    • A genomic view of alternative splicing
    • Modrek B and Lee C (2002) A genomic view of alternative splicing. Nat Genet 30:13-19.
    • (2002) Nat Genet , vol.30 , pp. 13-19
    • Modrek, B.1    Lee, C.2
  • 21
    • 0034810088 scopus 로고    scopus 로고
    • Epidermal growth factor inhibits glycylsarcosine transport and hPepT1 expression in a human intestinal cell line
    • Nielsen CU, Amstrup J, Steffansen B, Frokjaer S, and Brodin B (2001) Epidermal growth factor inhibits glycylsarcosine transport and hPepT1 expression in a human intestinal cell line. Am J Physiol 281:G191-G199.
    • (2001) Am J Physiol , vol.281
    • Nielsen, C.U.1    Amstrup, J.2    Steffansen, B.3    Frokjaer, S.4    Brodin, B.5
  • 22
    • 0037636412 scopus 로고    scopus 로고
    • Intraand interindividual variabilities of valacyclovir oral bioavailability and effect of coadministration of an hPEPT1 inhibitor
    • Phan DD, Chin-Hong P, Lin ET, Anderle P, Sadee W, and Guglielmo BJ (2003) Intraand interindividual variabilities of valacyclovir oral bioavailability and effect of coadministration of an hPEPT1 inhibitor. Antimicrob Agents Chemother 47:2351-2353.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2351-2353
    • Phan, D.D.1    Chin-Hong, P.2    Lin, E.T.3    Anderle, P.4    Sadee, W.5    Guglielmo, B.J.6
  • 23
    • 10044254337 scopus 로고    scopus 로고
    • Genetic variants of the human H/dipeptide transporter PEPT2: Analysis of haplotype functions
    • Pinsonneault J, Nielsen CU, and Sadee W (2004) Genetic variants of the human H/dipeptide transporter PEPT2: analysis of haplotype functions. J Pharmacol Exp Ther 311:1088-1096.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 1088-1096
    • Pinsonneault, J.1    Nielsen, C.U.2    Sadee, W.3
  • 24
    • 0036855185 scopus 로고    scopus 로고
    • Abundant raw material for cis-regulatory evolution in humans
    • Rockman MV and Wray GA (2002) Abundant raw material for cis-regulatory evolution in humans. Mol Biol Evol 19:1991-2004.
    • (2002) Mol Biol Evol , vol.19 , pp. 1991-2004
    • Rockman, M.V.1    Wray, G.A.2
  • 25
    • 0031589535 scopus 로고    scopus 로고
    • Cloning and characterization of a pH-sensing regulatory factor that modulates transport activity of the human H/peptide cotransporter, PEPT1
    • Saito H, Motohashi H, Mukai M, and Inui K (1997) Cloning and characterization of a pH-sensing regulatory factor that modulates transport activity of the human H/peptide cotransporter, PEPT1. Biochem Biophys Res Commun 237:577-582.
    • (1997) Biochem Biophys Res Commun , vol.237 , pp. 577-582
    • Saito, H.1    Motohashi, H.2    Mukai, M.3    Inui, K.4
  • 27
    • 0024313579 scopus 로고
    • Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
    • Tajima F (1989) Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123:585-595.
    • (1989) Genetics , vol.123 , pp. 585-595
    • Tajima, F.1
  • 28
    • 0035783146 scopus 로고    scopus 로고
    • Genomic structure of proton-coupled oligopeptide transporter hPEPT1 and pH-sensing regulatory splice variant
    • Urtti A, Johns SJ, and SadeeW(2001) Genomic structure of proton-coupled oligopeptide transporter hPEPT1 and pH-sensing regulatory splice variant. AAPS Pharm-Sci 3:E6.
    • (2001) AAPS Pharm-Sci , vol.3
    • Urtti, A.1    Johns, S.J.2    Sadee, W.3
  • 29
    • 25144433260 scopus 로고    scopus 로고
    • Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability
    • Wang D, Johnson AD, Papp A, Kroetz DL, and Sadee W (2005) Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenet Genomics 15:693-704.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 693-704
    • Wang, D.1    Johnson, A.D.2    Papp, A.3    Kroetz, D.L.4    Sadee, W.5
  • 32
    • 3343020872 scopus 로고    scopus 로고
    • Genetic polymorphisms in human proton-dependent dipeptide transporter PEPT1: Implications for the functional role of Pro586
    • Zhang EY, Fu DJ, Pak YA, Stewart T, Mukhopadhyay N, Wrighton SA, and Hillgren KM (2004) Genetic polymorphisms in human proton-dependent dipeptide transporter PEPT1: implications for the functional role of Pro586. J Pharmacol Exp Ther 310:437-445.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 437-445
    • Zhang, E.Y.1    Fu, D.J.2    Pak, Y.A.3    Stewart, T.4    Mukhopadhyay, N.5    Wrighton, S.A.6    Hillgren, K.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.