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Volumn 4, Issue 12, 2005, Pages 1395-1400

Ionizing radiation inhibits tumor neovascularization by inducing ineffective angiogenesis

Author keywords

Angiogenesis inhibition; Radiation therapy

Indexed keywords

FS 069; KI 67 ANTIGEN; VASCULOTROPIN;

EID: 31144449264     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.4.12.2331     Document Type: Article
Times cited : (48)

References (46)
  • 2
    • 4544384318 scopus 로고    scopus 로고
    • Radiation oncology: A century of achievements
    • Bernier J, Hall EJ, Giaccia A. Radiation oncology: A century of achievements. Nat Rev Cancer 2004; 4:737-47.
    • (2004) Nat Rev Cancer , vol.4 , pp. 737-747
    • Bernier, J.1    Hall, E.J.2    Giaccia, A.3
  • 4
    • 0035527317 scopus 로고    scopus 로고
    • New concepts in radiation-induced apoptosis: 'Premitotic apoptosis' and 'postmitotic apoptosis
    • Shinomiya N. New concepts in radiation-induced apoptosis: 'Premitotic apoptosis' and 'postmitotic apoptosis. J Cell Mol Med 2001; 5:240-53.
    • (2001) J Cell Mol Med , vol.5 , pp. 240-253
    • Shinomiya, N.1
  • 5
    • 0017142392 scopus 로고
    • Effects of X-rays on vascular function in transplanted tumours and normal tissues in the mouse
    • Zanelli GD, Lucas PB. Effects of X-rays on vascular function in transplanted tumours and normal tissues in the mouse. Br J Cancer 1976; 34:408-17.
    • (1976) Br J Cancer , vol.34 , pp. 408-417
    • Zanelli, G.D.1    Lucas, P.B.2
  • 6
    • 0024437527 scopus 로고
    • The response of the microvascular system to radiation: A review
    • Baker DG, Krochak RJ. The response of the microvascular system to radiation: A review. Cancer Invest 1989; 7:287-94.
    • (1989) Cancer Invest , vol.7 , pp. 287-294
    • Baker, D.G.1    Krochak, R.J.2
  • 7
    • 0035854479 scopus 로고    scopus 로고
    • Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
    • Paris F, et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 2001; 293:293-7.
    • (2001) Science , vol.293 , pp. 293-297
    • Paris, F.1
  • 8
    • 0041589527 scopus 로고    scopus 로고
    • Microvascular function regulates intestinal crypt response to radiation
    • Maj JG, et al. Microvascular function regulates intestinal crypt response to radiation. Cancer Res 2003; 63:4338-41.
    • (2003) Cancer Res , vol.63 , pp. 4338-4341
    • Maj, J.G.1
  • 9
    • 0038626211 scopus 로고    scopus 로고
    • Tumor response to radiotherapy regulated by endothelial cell apoptosis
    • Garcia-Barros M, et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003; 300:1155-9.
    • (2003) Science , vol.300 , pp. 1155-1159
    • Garcia-Barros, M.1
  • 10
    • 0035854505 scopus 로고    scopus 로고
    • Cancer. What does radiotherapy do to endothelial cells?
    • Folkman J, Camphausen K. Cancer. What does radiotherapy do to endothelial cells? Science 2001; 293:227-8.
    • (2001) Science , vol.293 , pp. 227-228
    • Folkman, J.1    Camphausen, K.2
  • 11
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407:249-57.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 12
    • 0035866771 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy
    • Geng L, et al. Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy. Cancer Res 2001; 61:2413-9.
    • (2001) Cancer Res , vol.61 , pp. 2413-2419
    • Geng, L.1
  • 13
    • 0041672482 scopus 로고    scopus 로고
    • SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models
    • Schueneman AJ, et al. SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models. Cancer Res 2003; 63:4009-16.
    • (2003) Cancer Res , vol.63 , pp. 4009-4016
    • Schueneman, A.J.1
  • 14
    • 19944422751 scopus 로고    scopus 로고
    • Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases
    • Winkler F, et al. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell 2004; 6:553-63.
    • (2004) Cancer Cell , vol.6 , pp. 553-563
    • Winkler, F.1
  • 15
    • 23644453277 scopus 로고    scopus 로고
    • Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity
    • Moeller BJ, et al. Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity. Cancer Cell 2005; 8:99-110.
    • (2005) Cancer Cell , vol.8 , pp. 99-110
    • Moeller, B.J.1
  • 16
    • 0033214696 scopus 로고    scopus 로고
    • Hypoxia-mediated apoptosis from angiogenesis inhibition underlies tumor control by recombinant interleukin 12
    • Gee MS, et al. Hypoxia-mediated apoptosis from angiogenesis inhibition underlies tumor control by recombinant interleukin 12. Cancer Res 1999; 59:4882-9.
    • (1999) Cancer Res , vol.59 , pp. 4882-4889
    • Gee, M.S.1
  • 17
    • 0035300539 scopus 로고    scopus 로고
    • Doppler ultrasound imaging detects changes in tumor perfusion during antivascular therapy associated with vascular anatomic alterations
    • Gee MS, et al. Doppler ultrasound imaging detects changes in tumor perfusion during antivascular therapy associated with vascular anatomic alterations. Cancer Res 2001; 61:2974-82.
    • (2001) Cancer Res , vol.61 , pp. 2974-2982
    • Gee, M.S.1
  • 18
    • 15444366529 scopus 로고    scopus 로고
    • Oxygen distribution in murine tumors: Characterization using oxygen-dependent quenching of phosphorescence
    • Ziemer LS, Lee WM, Vinogradov SA, Sehgal C, Wilson DF. Oxygen distribution in murine tumors: Characterization using oxygen-dependent quenching of phosphorescence. J Appl Physiol 2005; 98:1503-10.
    • (2005) J Appl Physiol , vol.98 , pp. 1503-1510
    • Ziemer, L.S.1    Lee, W.M.2    Vinogradov, S.A.3    Sehgal, C.4    Wilson, D.F.5
  • 19
    • 0029328266 scopus 로고
    • Intratumor microvessel density as a prognostic factor in cancer
    • Weidner N. Intratumor microvessel density as a prognostic factor in cancer. Am J Pathol 1995; 147:9-19.
    • (1995) Am J Pathol , vol.147 , pp. 9-19
    • Weidner, N.1
  • 20
    • 0027376264 scopus 로고
    • Detection of hypoxic cells by monoclonal antibody recognizing 2-nitroimidazole adducts
    • Lord EM, Harwell L, Koch CJ. Detection of hypoxic cells by monoclonal antibody recognizing 2-nitroimidazole adducts. Cancer Res 1993; 53:5721-6.
    • (1993) Cancer Res , vol.53 , pp. 5721-5726
    • Lord, E.M.1    Harwell, L.2    Koch, C.J.3
  • 21
    • 0037225847 scopus 로고    scopus 로고
    • The role of tumor oxygenation in vascular and clinical response to angiogenesis inhibition
    • Gee MS, Lee WM. The role of tumor oxygenation in vascular and clinical response to angiogenesis inhibition. Adv Exp Med Biol 2003; 510:1-5.
    • (2003) Adv Exp Med Biol , vol.510 , pp. 1-5
    • Gee, M.S.1    Lee, W.M.2
  • 22
    • 2342611976 scopus 로고    scopus 로고
    • Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: Role of reoxygenation, free radicals, and stress granules
    • Moeller BJ, Cao Y, Li CY, Dewhirst MW. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: Role of reoxygenation, free radicals, and stress granules. Cancer Cell 2004; 5:429-41.
    • (2004) Cancer Cell , vol.5 , pp. 429-441
    • Moeller, B.J.1    Cao, Y.2    Li, C.Y.3    Dewhirst, M.W.4
  • 23
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia - A key regulatory factor in tumour growth
    • Harris AL. Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2002; 2:38-47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 24
    • 0037223555 scopus 로고    scopus 로고
    • Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy
    • Gee MS, et al. Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy. Am J Pathol 2003; 162:183-93.
    • (2003) Am J Pathol , vol.162 , pp. 183-193
    • Gee, M.S.1
  • 25
    • 3543114272 scopus 로고    scopus 로고
    • Biologically active sphingolipids in cancer pathogenesis and treatment
    • Ogretmen B, Hannun YA. Biologically active sphingolipids in cancer pathogenesis and treatment. Nat Rev Cancer 2004; 4:604-16.
    • (2004) Nat Rev Cancer , vol.4 , pp. 604-616
    • Ogretmen, B.1    Hannun, Y.A.2
  • 26
    • 3843124144 scopus 로고    scopus 로고
    • A sense of danger from radiation
    • McBride WH, et al. A sense of danger from radiation. Radiat Res 2004; 162:1-19.
    • (2004) Radiat Res , vol.162 , pp. 1-19
    • McBride, W.H.1
  • 27
    • 0034877938 scopus 로고    scopus 로고
    • Induction of a senescence-like phenotype in bovine aortic endothelial cells by ionizing radiation
    • Oh CW, Bump EA, Kim JS, Janigro D, Mayberg MR. Induction of a senescence-like phenotype in bovine aortic endothelial cells by ionizing radiation. Radiat Res 2001; 156:232-40.
    • (2001) Radiat Res , vol.156 , pp. 232-240
    • Oh, C.W.1    Bump, E.A.2    Kim, J.S.3    Janigro, D.4    Mayberg, M.R.5
  • 28
    • 0036468547 scopus 로고    scopus 로고
    • Interleukin-12 inhibits angiogenesis and growth of transplanted but not in situ mouse mammary tumor virus-induced mammary carcinomas
    • Lee JC, et al. Interleukin-12 inhibits angiogenesis and growth of transplanted but not in situ mouse mammary tumor virus-induced mammary carcinomas. Cancer Res 2002; 62:747-55.
    • (2002) Cancer Res , vol.62 , pp. 747-755
    • Lee, J.C.1
  • 29
    • 0038476608 scopus 로고    scopus 로고
    • Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
    • Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 2003; 111:1287-95.
    • (2003) J Clin Invest , vol.111 , pp. 1287-1295
    • Bergers, G.1    Song, S.2    Meyer-Morse, N.3    Bergsland, E.4    Hanahan, D.5
  • 30
    • 0031834239 scopus 로고    scopus 로고
    • A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin LE, Hemo I, Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 1998; 125:1591-8.
    • (1998) Development , vol.125 , pp. 1591-1598
    • Benjamin, L.E.1    Hemo, I.2    Keshet, E.3
  • 31
    • 3042548695 scopus 로고    scopus 로고
    • Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts
    • Inai T, et al. Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts. Am J Pathol 2004; 165:35-52.
    • (2004) Am J Pathol , vol.165 , pp. 35-52
    • Inai, T.1
  • 32
    • 0345734280 scopus 로고    scopus 로고
    • Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition
    • Gee MS, et al. Selective cytokine inhibitory drugs with enhanced antiangiogenic activity control tumor growth through vascular inhibition. Cancer Res 2003; 63:8073-8.
    • (2003) Cancer Res , vol.63 , pp. 8073-8078
    • Gee, M.S.1
  • 33
    • 0031469819 scopus 로고    scopus 로고
    • Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
    • Boehm T, Folkman J, Browder T, O'Reilly MS. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 1997; 390:404-7.
    • (1997) Nature , vol.390 , pp. 404-407
    • Boehm, T.1    Folkman, J.2    Browder, T.3    O'Reilly, M.S.4
  • 34
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly MS, et al. Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994; 79:315-28.
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1
  • 35
    • 12244296444 scopus 로고    scopus 로고
    • Effect of the tumor vascular-damaging agent, ZD6126, on the radioresponse of U87 glioblastoma
    • Wachsberger PR, et al. Effect of the tumor vascular-damaging agent, ZD6126, on the radioresponse of U87 glioblastoma. Clin Cancer Res 2005; 11:835-42.
    • (2005) Clin Cancer Res , vol.11 , pp. 835-842
    • Wachsberger, P.R.1
  • 36
    • 12244252749 scopus 로고    scopus 로고
    • Gene therapy delivery of endostatin enhances the treatment efficacy of radiation
    • Shi W, Teschendorf C, Muzyczka N, Siemann DW. Gene therapy delivery of endostatin enhances the treatment efficacy of radiation. Radiother Oncol 2003; 66:1-9.
    • (2003) Radiother Oncol , vol.66 , pp. 1-9
    • Shi, W.1    Teschendorf, C.2    Muzyczka, N.3    Siemann, D.W.4
  • 37
    • 0036681995 scopus 로고    scopus 로고
    • Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa)
    • Huang SM, Li J, Armstrong EA, Harari PM. Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa). Cancer Res 2002; 62:4300-6.
    • (2002) Cancer Res , vol.62 , pp. 4300-4306
    • Huang, S.M.1    Li, J.2    Armstrong, E.A.3    Harari, P.M.4
  • 38
    • 0036569804 scopus 로고    scopus 로고
    • Enhancement of radiation therapy by the novel vascular targeting agent ZD6126
    • Siemann DW, Rojiani AM. Enhancement of radiation therapy by the novel vascular targeting agent ZD6126. Int J Radiat Oncol Biol Phys 2002; 53:164-71.
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 164-171
    • Siemann, D.W.1    Rojiani, A.M.2
  • 39
    • 0035555907 scopus 로고    scopus 로고
    • Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth
    • Hess C, et al. Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth. Br J Cancer 2001; 85:2010-6.
    • (2001) Br J Cancer , vol.85 , pp. 2010-2016
    • Hess, C.1
  • 40
    • 0035132923 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts
    • Kozin SV, et al. Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts. Cancer Res 2001; 61:39-44.
    • (2001) Cancer Res , vol.61 , pp. 39-44
    • Kozin, S.V.1
  • 41
    • 0034306974 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions
    • Lee CG, et al. Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. Cancer Res 2000; 60:5565-70.
    • (2000) Cancer Res , vol.60 , pp. 5565-5570
    • Lee, C.G.1
  • 42
    • 12944331952 scopus 로고    scopus 로고
    • Combined effects of radiotherapy and angiostatin gene therapy in glioma tumor model
    • USA
    • Griscelli F, et al. Combined effects of radiotherapy and angiostatin gene therapy in glioma tumor model. Proc Natl Acad Sci USA 2000; 97:6698-703.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 6698-6703
    • Griscelli, F.1
  • 43
    • 0034099423 scopus 로고    scopus 로고
    • Therapeutic synergy of TNP-470 and ionizing radiation: Effects on tumor growth, vessel morphology, and angiogenesis in human glioblastoma multiforme xenografts
    • Lund EL, Bastholm L, Kristjansen PE. Therapeutic synergy of TNP-470 and ionizing radiation: Effects on tumor growth, vessel morphology, and angiogenesis in human glioblastoma multiforme xenografts. Clin Cancer Res 2000; 6:971-8.
    • (2000) Clin Cancer Res , vol.6 , pp. 971-978
    • Lund, E.L.1    Bastholm, L.2    Kristjansen, P.E.3
  • 44
    • 0033564974 scopus 로고    scopus 로고
    • Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation
    • Gorski DH, et al. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res 1999; 59:3374-8.
    • (1999) Cancer Res , vol.59 , pp. 3374-3378
    • Gorski, D.H.1
  • 45
    • 18244419396 scopus 로고    scopus 로고
    • Combined effects of angiostatin and ionizing radiation in antitumour therapy
    • Mauceri HJ, et al. Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature 1998; 394:287-91.
    • (1998) Nature , vol.394 , pp. 287-291
    • Mauceri, H.J.1
  • 46
    • 0030971274 scopus 로고    scopus 로고
    • An antiangiogenie agent (TNP-470) inhibited reoxygenation during fractionated radiotherapy of murine mammary carcinoma
    • Murata R, Nishimura Y, Hiraoka M. An antiangiogenie agent (TNP-470) inhibited reoxygenation during fractionated radiotherapy of murine mammary carcinoma. Int J Radiat Oncol Biol Phys 1997; 37:1107-13.
    • (1997) Int J Radiat Oncol Biol Phys , vol.37 , pp. 1107-1113
    • Murata, R.1    Nishimura, Y.2    Hiraoka, M.3


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