Malagashanine potentiates chloroquine antimalarial activity in drug resistant Plasmodium malaria by modifying both its efflux and influx

Molecular and Biochemical Parasitology

Volumn 146, Issue 1, 2006, Pages 58-67

  Ramanitrahasimbola, David ^a   Rasoanaivo, Philippe ^a   Ratsimamanga, Suzanne ^a   Vial, Henri ^b  

^a INSTITUT MALGACHE DE RECHERCHES APPLIQUÉES   (Madagascar)

^b CNRS   (France)

Author keywords

Chemosensitizer; Chloroquine resistance; Chloroquine transporter; Efflux; Malagashanine; Plasmodium

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; MALAGASHANINE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIMALARIAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG EFFECT; DRUG POTENTIATION; EFFUSION; HUMAN; HUMAN CELL; INCUBATION TIME; NONHUMAN; PLASMODIUM FALCIPARUM; PLASMODIUM MALARIAE; PRIORITY JOURNAL; TROPHOZOITE;

ALKALOIDS; ANIMALS; ANTIMALARIALS; CHLOROQUINE; CULTURE MEDIA; DRUG RESISTANCE; DRUG SYNERGISM; ERYTHROCYTES; GLUCOSE; HYPOXANTHINE; LIFE CYCLE STAGES; MALARIA, FALCIPARUM; PARASITIC SENSITIVITY TESTS; PLASMODIUM FALCIPARUM; TIME FACTORS;

PLASMODIUM FALCIPARUM; PLASMODIUM MALARIAE; STRYCHNOS;

EID: 31144448376     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2005.10.018     Document Type: Article

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