The immunomodulator ginsan induces resistance to experimental sepsis by inhibiting Toll-like receptor-mediated inflammatory signals

European Journal of Immunology

Volumn 36, Issue 1, 2006, Pages 37-45

  Ahn, Ji Yeon ^a,b   Choi, In Soo ^c   Shim, Ji Young ^a   Yun, Eun Kyung ^a   Yun, Yeon Sook ^a   Jeong, Gajin ^b   Song, Jie Young ^a  

^a Korea Institute of Radiation and Medical Science   (South Korea)

^b Seoul National University   (South Korea)

^c Konkuk University   (South Korea)

Author keywords

Ginsan; Sepsis; Staphyloccus aureus

Indexed keywords

GAMMA INTERFERON; GINSENG EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC PROPHYLAXIS; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIUM CULTURE; CIRCULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG DOSE REGIMEN; DRUG MECHANISM; DRUG RESPONSE; IMMUNOSTIMULATION; IN VITRO STUDY; INFLAMMATION; KIDNEY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; SIGNAL TRANSDUCTION; SPLEEN; STAPHYLOCOCCUS AUREUS; SURVIVAL RATE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTI-INFLAMMATORY AGENTS; CYTOKINES; DISEASE MODELS, ANIMAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PANAX; PHAGOCYTOSIS; PLANT EXTRACTS; POLYSACCHARIDES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEPSIS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTORS;

EID: 30944443792     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200535138     Document Type: Article

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