메뉴 건너뛰기




Volumn 46, Issue 4, 2005, Pages 236-245

Use of genetic toxicology information for risk assessment

Author keywords

Genetic toxicology; Mutagenic mode of action; Risk assessment

Indexed keywords

CARCINOGEN; DRUG; PESTICIDE;

EID: 30844437463     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20176     Document Type: Review
Times cited : (50)

References (46)
  • 1
    • 0030864329 scopus 로고    scopus 로고
    • Development and utilization of the rat lymphocyte hprt mutation assay
    • Aidoo A, Morris SM, Casciano DA. 1997. Development and utilization of the rat lymphocyte hprt mutation assay. Mutat Res 387:69-88.
    • (1997) Mutat Res , vol.387 , pp. 69-88
    • Aidoo, A.1    Morris, S.M.2    Casciano, D.A.3
  • 2
    • 0027752786 scopus 로고
    • Somatic cell gene mutations in humans: Biomarkers for genotoxicity
    • Albertini RJ, Nicklas JA, O'Neill JP. 1993. Somatic cell gene mutations in humans: biomarkers for genotoxicity. Environ Health Perspect 101(Suppl 3):193-201.
    • (1993) Environ Health Perspect , vol.101 , Issue.SUPPL. 3 , pp. 193-201
    • Albertini, R.J.1    Nicklas, J.A.2    O'Neill, J.P.3
  • 3
    • 0016685233 scopus 로고
    • Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test
    • Ames BN, McCann J, Yamasaki E. 1975. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mutat Res 31:347-364.
    • (1975) Mutat Res , vol.31 , pp. 347-364
    • Ames, B.N.1    McCann, J.2    Yamasaki, E.3
  • 4
    • 0025060317 scopus 로고
    • Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells
    • Applegate ML, Moore MM, Broder CB, Burrell A, Hozier JC. 1990. Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells. Proc Natl Acad Sci USA 87:51-55.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 51-55
    • Applegate, M.L.1    Moore, M.M.2    Broder, C.B.3    Burrell, A.4    Hozier, J.C.5
  • 5
    • 0023010822 scopus 로고
    • Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations
    • Brusick D. 1986. Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations. Environ Mutagen 8:879-886.
    • (1986) Environ Mutagen , vol.8 , pp. 879-886
    • Brusick, D.1
  • 6
    • 0027170192 scopus 로고
    • ENU-induced mutagenesis at a single A:T base pair in transgenic mice containing φ X174
    • Burkhart JG, Burkhart BA, Sampson KS, Malling HV. 1993. ENU-induced mutagenesis at a single A:T base pair in transgenic mice containing φ X174. Mutat Res 292:69-81.
    • (1993) Mutat Res , vol.292 , pp. 69-81
    • Burkhart, J.G.1    Burkhart, B.A.2    Sampson, K.S.3    Malling, H.V.4
  • 8
    • 0011440874 scopus 로고    scopus 로고
    • New OECD genetic toxicology guidelines and interpretation of results
    • Choy WN, editor. New York: Marcel Dekker
    • Cimino MC. 2001. New OECD genetic toxicology guidelines and interpretation of results. In: Choy WN, editor. Genetic Toxicology and Cancer Risk Assessment. New York: Marcel Dekker, pp 223-248.
    • (2001) Genetic Toxicology and Cancer Risk Assessment , pp. 223-248
    • Cimino, M.C.1
  • 10
    • 0036151312 scopus 로고    scopus 로고
    • A consistent approach for the application of pharmacokinetic modeling in cancer and noncancer risk assessment
    • Clewell HJ, III, Andersen ME, Barton HA. 2002. A consistent approach for the application of pharmacokinetic modeling in cancer and noncancer risk assessment. Environ Health Perspect 110:85-93.
    • (2002) Environ Health Perspect , vol.110 , pp. 85-93
    • Clewell III, H.J.1    Andersen, M.E.2    Barton, H.A.3
  • 11
    • 0016423549 scopus 로고
    • Laboratory procedure for assessing specific locus mutations at the TK locus in cultured L5178Y mouse lymphoma cells
    • Clive D, Spector JF. 1975. Laboratory procedure for assessing specific locus mutations at the TK locus in cultured L5178Y mouse lymphoma cells. Mutat Res 31:17-29.
    • (1975) Mutat Res , vol.31 , pp. 17-29
    • Clive, D.1    Spector, J.F.2
  • 12
    • 0003500730 scopus 로고    scopus 로고
    • London: Department of Health
    • Committee on Mutagenicity of Chemicals in Food, Consumer Products and the Environment (COM). 2000. Guidance on a Strategy for Testing of Chemicals for Mutagenicity. London: Department of Health. Available at http://www. advisorybodies.doh.gov.uk/Com/guidance.pdf.
    • (2000) Guidance on a Strategy for Testing of Chemicals for Mutagenicity
  • 13
    • 0343072811 scopus 로고
    • Considerations in the U.S. Environmental Protection Agency's testing approach for mutagenicity
    • Dearfield KL, Auletta AE, Cimino MC, Moore MM. 1991. Considerations in the U.S. Environmental Protection Agency's testing approach for mutagenicity. Mutat Res 258:259-283.
    • (1991) Mutat Res , vol.258 , pp. 259-283
    • Dearfield, K.L.1    Auletta, A.E.2    Cimino, M.C.3    Moore, M.M.4
  • 14
    • 0033565724 scopus 로고    scopus 로고
    • A survey of EPA/OPP and open literature on selected pesticide chemicals. II. Mutagenicity and carcinogenicity of selected chloroacetanilides and related compounds
    • Dearfield KL, McCarroll NE, Protzel A, Stack HF, Jackson MA, Waters MD. 1999. A survey of EPA/OPP and open literature on selected pesticide chemicals. II. Mutagenicity and carcinogenicity of selected chloroacetanilides and related compounds. Mutat Res 443: 183-221.
    • (1999) Mutat Res , vol.443 , pp. 183-221
    • Dearfield, K.L.1    McCarroll, N.E.2    Protzel, A.3    Stack, H.F.4    Jackson, M.A.5    Waters, M.D.6
  • 18
    • 0024523360 scopus 로고
    • Kinetochore detection in micronuclei: An alternative method for measuring chromosome loss
    • Fenech M, Morley AA. 1989. Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss. Mutagen 4: 98-104.
    • (1989) Mutagen , vol.4 , pp. 98-104
    • Fenech, M.1    Morley, A.A.2
  • 19
    • 0034032414 scopus 로고    scopus 로고
    • Cytotoxicity and chromosome aberrations in vitro: Experience in industry and the case of an upper limit on toxicity in the aberration assay
    • Galloway SM. 2000. Cytotoxicity and chromosome aberrations in vitro: experience in industry and the case of an upper limit on toxicity in the aberration assay. Environ Mol Mutagen 35:191-201.
    • (2000) Environ Mol Mutagen , vol.35 , pp. 191-201
    • Galloway, S.M.1
  • 21
    • 16644380629 scopus 로고    scopus 로고
    • The GPA in vivo somatic mutation assay
    • Grant SG. 2005. The GPA in vivo somatic mutation assay. Methods Mol Biol 291:179-195.
    • (2005) Methods Mol Biol , vol.291 , pp. 179-195
    • Grant, S.G.1
  • 23
    • 0020511885 scopus 로고
    • The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program
    • Heddle JA, Hite M, Kirkhart B, Mavournin K, MacGregor JT, Newell GW, Salamone MF. 1983. The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res 123:61-118.
    • (1983) Mutat Res , vol.123 , pp. 61-118
    • Heddle, J.A.1    Hite, M.2    Kirkhart, B.3    Mavournin, K.4    MacGregor, J.T.5    Newell, G.W.6    Salamone, M.F.7
  • 25
    • 30844446397 scopus 로고    scopus 로고
    • Lyon, France, February 16-18, 1999. IPCS/99.6. Geneva: World Health Organization
    • International Programme on Chemical Safety (IPCS). 1999. IPCS Workshop on Developing a Conceptual Framework for Cancer Risk Assessment, Lyon, France, February 16-18, 1999. IPCS/99.6. Geneva: World Health Organization.
    • (1999) IPCS Workshop on Developing a Conceptual Framework for Cancer Risk Assessment
  • 26
    • 22244450327 scopus 로고    scopus 로고
    • Use of genotoxicity data to support clinical trials or positive genetox findings on a candidate pharmaceutical or impurity ... Now what?
    • Jacobson-Kram D, Jacobs A. 2005. Use of genotoxicity data to support clinical trials or positive genetox findings on a candidate pharmaceutical or impurity ... now what? Int J Toxicol 24:129-134.
    • (2005) Int J Toxicol , vol.24 , pp. 129-134
    • Jacobson-Kram, D.1    Jacobs, A.2
  • 27
    • 0029810641 scopus 로고    scopus 로고
    • Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage λ transgene target
    • Jakubczak JL, Merlino G, French JE, Muller WJ, Paul B, Adhya S, Garges S. 1996. Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage λ transgene target. Proc Natl Acad Sci USA 93:9073-9078.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9073-9078
    • Jakubczak, J.L.1    Merlino, G.2    French, J.E.3    Muller, W.J.4    Paul, B.5    Adhya, S.6    Garges, S.7
  • 30
    • 0000820622 scopus 로고
    • A new Salmonella tester strain (TA102) with AXT base pairs at the site of mutation detects oxidative mutagens
    • Levin DE, Hollstein M, Christman MF, Schwiers EA, Ames BN. 1982a. A new Salmonella tester strain (TA102) with AXT base pairs at the site of mutation detects oxidative mutagens. Proc Natl Acad Sci USA 79:7445-7449.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 7445-7449
    • Levin, D.E.1    Hollstein, M.2    Christman, M.F.3    Schwiers, E.A.4    Ames, B.N.5
  • 31
    • 0019965761 scopus 로고
    • A new Salmonella tester strain, TA97, for the detection of frameshift mutagens. A run of cytosines as a mutational hot-spot
    • Levin DE, Yamasaki E, Ames BN. 1982b. A new Salmonella tester strain, TA97, for the detection of frameshift mutagens. A run of cytosines as a mutational hot-spot. Mutat Res 94:315-330.
    • (1982) Mutat Res , vol.94 , pp. 315-330
    • Levin, D.E.1    Yamasaki, E.2    Ames, B.N.3
  • 32
    • 0036709215 scopus 로고    scopus 로고
    • A survey of EPA/OPP and open literature on selected pesticide chemicals. III. Mutagenicity and carcinogenicity of benomyl and carbendazim
    • McCarroll NE, Protzel A. Ioannou Y, Stack HF, Jackson MA, Waters MD, Dearfield KL. 2002. A survey of EPA/OPP and open literature on selected pesticide chemicals. III. Mutagenicity and carcinogenicity of benomyl and carbendazim. Mutat Res 512:1-35.
    • (2002) Mutat Res , vol.512 , pp. 1-35
    • McCarroll, N.E.1    Protzel, A.2    Ioannou, Y.3    Stack, H.F.4    Jackson, M.A.5    Waters, M.D.6    Dearfield, K.L.7
  • 33
    • 0033932461 scopus 로고    scopus 로고
    • Mutagenicity of trichloroethylene and its metabolites: Implications for the risk assessment of trichloroethylene
    • Moore MM, Harrington-Brock K. 2000. Mutagenicity of trichloroethylene and its metabolites: implications for the risk assessment of trichloroethylene. Environ Health Perspect 108(Suppl 2):215-223.
    • (2000) Environ Health Perspect , vol.108 , Issue.SUPPL. 2 , pp. 215-223
    • Moore, M.M.1    Harrington-Brock, K.2
  • 34
    • 0024421263 scopus 로고
    • Differential mutant quantitation at the mouse lymphoma tk and CHO hgprt loci
    • Moore MM, Harrington-Brock K, Doerr CL, Dearfield KL. 1989. Differential mutant quantitation at the mouse lymphoma tk and CHO hgprt loci. Mutagen 4:394-403.
    • (1989) Mutagen , vol.4 , pp. 394-403
    • Moore, M.M.1    Harrington-Brock, K.2    Doerr, C.L.3    Dearfield, K.L.4
  • 37
    • 0003479926 scopus 로고    scopus 로고
    • Paris: OECD
    • Organization for Economic Cooperation and Development (OECD). 1998. OECD Guidelines for the Testing of Chemicals. Paris: OECD. Available at www.oecd.org.
    • (1998) OECD Guidelines for the Testing of Chemicals
  • 38
    • 0035983146 scopus 로고    scopus 로고
    • Occurrence of H-ras codon 61 CAA to AAA mutation during mouse liver tumor progression
    • Parsons BL, Culp S, Manjanatha M, Heflich RH. 2002. Occurrence of H-ras codon 61 CAA to AAA mutation during mouse liver tumor progression. Carcinogenesis 23:943-948.
    • (2002) Carcinogenesis , vol.23 , pp. 943-948
    • Parsons, B.L.1    Culp, S.2    Manjanatha, M.3    Heflich, R.H.4
  • 41
    • 0001372175 scopus 로고
    • Guidelines for mutagenicity risk assessment
    • US Environmental Protection Agency (USEPA). 1986. Guidelines for Mutagenicity Risk Assessment. Federal Register 51:34006-34012.
    • (1986) Federal Register , vol.51 , pp. 34006-34012
  • 43
    • 84884056304 scopus 로고    scopus 로고
    • Washington, DC: Office of Prevention, Pesticides and Toxic Substances. EPA Publication No. EPA/712/C-98/212
    • US Environmental Protection Agency (USEPA). 1998. OPPTS Harmonized Test Guidelines, Series 870, Health Effects Test Guidelines - Final Guidelines. Washington, DC: Office of Prevention, Pesticides and Toxic Substances. EPA Publication No. EPA/712/C-98/212. Available at http://www.epa.gov/opptsfrs/ OPPTS_Harmonized/870_Health_Effects_ Test_Guidelines/Series/.
    • (1998) OPPTS Harmonized Test Guidelines, Series 870, Health Effects Test Guidelines - Final Guidelines
  • 45
    • 30344443429 scopus 로고    scopus 로고
    • Washington, DC: Risk Assessment Forum, USEPA. EPA Publication No. EPA/630/P-03/001F
    • US Environmental Protection Agency (USEPA). 2005. Guidelines for Carcinogen Risk Assessment. Washington, DC: Risk Assessment Forum, USEPA. EPA Publication No. EPA/630/P-03/001F.
    • (2005) Guidelines for Carcinogen Risk Assessment
  • 46
    • 56449123963 scopus 로고    scopus 로고
    • Washington, DC: Office of Food Additive Safety, Center for Food Safety and Applied Nutrition, USFDA. (Last updated April 2004)
    • US Food and Drug Administration (USFDA). 2000. Redbook 2000. Toxicological Principles for the Safety Assessment of Food Ingredients. Washington, DC: Office of Food Additive Safety, Center for Food Safety and Applied Nutrition, USFDA. Available at http://www. cfsan.fda.gov/~redbook/red- toca.html (Last updated April 2004).
    • (2000) Redbook 2000. Toxicological Principles for the Safety Assessment of Food Ingredients


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.