The evaluation of some pharmaceutically acceptable excipients as permeation enhancers for amoxicillin

International Journal of Pharmaceutics

Volumn 308, Issue 1-2, 2006, Pages 84-89

  Legen, Igor ^a   Kračun, Matjaž ^a   Salobir, Mateja ^a   Kerč, Janez ^a  

^a Lek dd   (Slovenia)

Author keywords

Amoxicillin; Multidrug resistance associated protein (MRP); Permeation enhancement; Side by side diffusion cells; Sodium lauryl sulfate

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMOXICILLIN; BENZBROMARONE; CARBOMER; CARBOPOL 934; CREMOPHOR; DODECYL SULFATE SODIUM; EXCIPIENT; GLUCOSE; LUTROL F127; MANNITOL; MULTIDRUG RESISTANCE PROTEIN; POLOXAMER; RANITIDINE; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG ELIMINATION; DRUG PENETRATION; DRUG TRANSPORT; INTESTINE; JEJUNUM; MALE; MUCOSA; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT; SEROSA;

AMOXICILLIN; ANIMALS; ANTI-BACTERIAL AGENTS; BENZBROMARONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; EXCIPIENTS; GLUCOSE; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; JEJUNUM; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; RATS; RATS, WISTAR; SODIUM DODECYL SULFATE;

EID: 30744474191     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2005.10.036     Document Type: Article

References (26)

1. B.J. Aungst Intestinal permeation enhancers J. Pharm. Sci. 89 2000 429 442
2. É. Bakos, R. Evers, E. Sinkó, A. Váradi, P. Borst, and B. Sarkadi Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions Mol. Pharmacol. 57 2000 760 768
3. N. Bandi, and U.B. Kompella Budesonide reduces multidrug resistance-associated protein 1 expression in an airway epithelial cell line (Calu-1) Eur. J. Pharmacol. 437 2002 9 17
4. K. Bogman, F. Erne-Brand, J. Alsenz, and J. Drewe The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins J. Pharm. Sci. 92 2003 1250 1261
5. A.V. Kabanov, E.V. Batrakova, and V.Y. Alakhov Pluronic block copolymers for overcoming drug resistance in cancer Adv. Drug. Deliv. Rev. 54 2002 759 779
6. I. Legen, and A. Kristl Ketoprofen-induced intestinal permeability changes studied in side-by-side diffusion cells J. Pharm. Pharmacol. 54 2002 1419 1422
7. I. Legen, and A. Kristl Factors affecting the microclimate pH of the rat jejunum in Ringer bicarbonate buffer Biol. Pharm. Bull. 26 2003 886 889
8. I. Legen, and A. Kristl d-glucose triggers multidrug resistance- associated protein (MRP)-mediated secretion of fluorescein across rat jejunum in vitro Pharm. Res. 21 2004 635 640
9. I. Legen, M. Salobir, and J. Kerc Comparison of different intestinal epithelia as models for absorption enhancement studies Int. J. Pharm. 291 2005 183 188
10. H. Lennernäs, L. Knutson, T. Knutson, A. Hussain, L. Lesko, T. Salmonson, and G.L. Amidon The effect of amiloride on the in vivo effective permeability of amoxicillin in human jejunum: experience from a regional perfusion technique Eur. J. Pharm. Sci. 15 2002 271 277
11. Y.L. Lo Relationships between the hydrophilic-lipophilic balance values of pharmaceutical excipients and their multidrug resistance modulating effect in Caco-2 cells and rat intestines J. Control. Release. 90 2003 37 48
12. R. Löbenberg, and G.L. Amidon Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards Eur. J. Pharm. Biopharm. 50 2000 3 12
13. F. Margarit, J. Moreno-Dalmau, R. Obach, C. Peraire, and J.M. Pla-Delfina Intestinal absorption kinetics of a series of aminopenicillins and azidocillin. A comparative study in the rat Eur. J. Drug. Metab. Pharmacokinet. 3 1991 102 107
14. M.M. Nerurkar, P.S. Burton, and R.T. Borchardt The use of surfactants to enhance the permeability of peptides through Caco-2 cells by inhibition of an apically polarized efflux system Pharm. Res. 13 1996 528 534
15. G. Paintaud, G. Alván, M.L. Dahl, A. Grahnén, J. Sjövall, and J.O. Svensson Nonlinearity of amoxicillin absorption kinetics in human Eur. J. Clin. Pharmacol. 43 1992 283 288
16. P.A. Redondo, A.I. Alvarez, J.L. Garcia, C. Villaverde, and J.G. Prieto Influence of surfactants on oral bioavailability of albendazole based on the formation of the sulphoxide metabolites in rats Biopharm. Drug. Dispos. 19 1998 65 70
17. B.D. Rege, J.P. Kao, and J.E. Polli Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers Eur. J. Pharm. Sci. 16 2002 237 246
18. H. Saitoh, H. Fujisaki, B.J. Aungst, and K. Miyazaki Restricted intestinal absorption of some beta-lactam antibiotics by an energy-dependent efflux system in rat intestine Pharm. Res. 14 1997 645 649
19. R.G. Schoenmakers, M.C. Stehouwer, and J.J. Tukker Structure-transport relationship for the intestinal small-peptide carrier: is the carbonyl group of the peptide bond relevant for transport? Pharm. Res. 16 1999 62 68
20. J. Sjövall, G. Alván, J.E. Åkerlund, J.O. Svensson, G. Paintaud, C.E. Nord, and B. Angelin Dose-dependent absorption of amoxicillin in patients with an ileostomy Eur. J. Clin. Pharmacol. 43 1992 277 281
21. J.D. Söderholm, L. Hedman, P. Artursson, L. Franzen, J. Larsson, N. Pantzar, J. Permert, and G. Olaison Integrity and metabolism of human ileal mucosa in vitro in the Ussing chamber Acta. Physiol. Scand. 162 1998 47 56
22. P.G. Welling, H. Huang, P.A. Koch, W.A. Craig, and P.O. Madsen Bioavailability of ampicillin and amoxicillin in fasted and nonfasted subjects J. Pharm. Sci. 66 1977 549 552
23. J.S. Woo, C.H. Lee, C.K. Shim, and S.J. Hwang Enhanced oral bioavailability of paclitaxel by coadministration of the P-glycoprotein inhibitor KR30031 Pharm. Res. 20 2003 24 30
24. N. Zelcer, M.T. Huisman, G. Reid, P. Wielinga, P. Breedveld, A. Kuil, P. Knipscheer, J.H. Schellens, A.H. Schinkel, and P. Borst Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2) J. Biol. Chem. 278 2003 23538 23544
25. Y.H. Zhao, J. Le, M.H. Abraham, A. Hersey, P.J. Eddershaw, C.N. Luscombe, D. Butina, G. Beck, B. Sherborne, I. Cooper, and J.A. Platts Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure-activity relationship (QSAR) with the Abraham descriptors J. Pharm. Sci. 90 2001 749 784
26. http://www.accessdata.fda.gov/scripts/cder/iig/index.cfm.