Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5′-ATP, Ap3A, Ap4A, and Ap 5A

Biochemistry

Volumn 45, Issue 2, 2006, Pages 416-426

  Baker, Matthew D ^a   Holloway, Daniel E ^a   Swaminathan, G Jawahar ^a,b   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

^b EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; CATALYSIS; ENZYMES; MEDICAL PROBLEMS; RNA; TOXIC MATERIALS; X RAY CRYSTALLOGRAPHY;

DIADENOSINE TRIPHOSPHATE (AP3A); EOSINOPHIL-DERIVED NEUROTOXIN (EDN); NEUROTOXIC ACTIVITIES; PANCREATIC RIBONUCLEASE SUPERFAMILY;

CRYSTAL STRUCTURE;

ADENOSINE TRIPHOSPHATE INHIBITOR; DIADENOSINE PENTAPHOSPHATE INHIBITOR; DIADENOSINE TETRAPHOSPHATE INHIBITOR; DIADENOSINE TRIPHOSPHATE INHIBITOR; EOSINOPHIL GRANULE PROTEIN; EOSINOPHIL PROTEIN X; NEUROTOXIN; NUCLEOTIDE; PANCREATIC RIBONUCLEASE; POLYPHOSPHATE; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ALLERGIC DISEASE; ANTIVIRAL ACTIVITY; ARTICLE; DRUG POTENCY; INFLAMMATORY DISEASE; INHIBITION KINETICS; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DINUCLEOSIDE PHOSPHATES; EOSINOPHIL-DERIVED NEUROTOXIN; HUMANS; PROTEIN STRUCTURE, TERTIARY;

EID: 30744432107     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0518592     Document Type: Article

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