Kinetic and product distribution analysis of human eosinophil cationic protein indicates a subsite arrangement that favors exonuclease-type activity

Journal of Biological Chemistry

Volumn 274, Issue 22, 1999, Pages 15605-15614

  Boix, Ester ^a   Nikolovski, Zoran ^a   Moiseyev, Gennady P ^a   Rosenberg, Helene F ^b   Cuchillo, Claudi M ^a   Nogués, M Victòria ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DINUCLEOSIDE PHOSPHATE; EOSINOPHIL CATIONIC PROTEIN; EXORIBONUCLEASE; POLYADENYLIC ACID; POLYURIDYLIC ACID; RECOMBINANT PROTEIN; RNA; ZINC ION;

ARTICLE; BINDING SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SPECIFICITY; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN RNA BINDING; PROTEIN TERTIARY STRUCTURE; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

BINDING SITES; BLOOD PROTEINS; ENZYME INHIBITORS; EOSINOPHIL GRANULE PROTEINS; EXONUCLEASES; HUMANS; KINETICS; MODELS, MOLECULAR; POLY C; POLY U; POLYNUCLEOTIDES; RECOMBINANT PROTEINS; RIBONUCLEASE, PANCREATIC; RIBONUCLEASES; SUBSTRATE SPECIFICITY;

BOVINAE; PROKARYOTA;

EID: 0033022636     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.22.15605     Document Type: Article

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