메뉴 건너뛰기




Volumn 47, Issue 2, 2006, Pages 307-312

Flt3-ITD mutations can generate leukaemia specific neoepitopes: Potential role for immunotherapeutic approaches

Author keywords

AML; Flt3 ITD; Immunotherapy; Mimotope; Neoepitope

Indexed keywords

EPITOPE; FLT3 LIGAND; HLA A1 ANTIGEN; HLA A2 ANTIGEN; HLA ANTIGEN CLASS 1; HLA B27 ANTIGEN;

EID: 30644477496     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/10428190500301306     Document Type: Article
Times cited : (16)

References (17)
  • 1
    • 0030451722 scopus 로고    scopus 로고
    • Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
    • Nakao, M and Yokota, S and Iwai, T and Kaneko, H and Horiike, S and Kashima, K and (1996) Internal tandem duplication of the flt3 gene found in acute myeloid leukemia Leukemia, 10, pp. 1911 - 1918.
    • (1996) Leukemia , vol.10 , pp. 1911-1918
    • Nakao, M.1    Yokota, S.2    Iwai, T.3    Kaneko, H.4    Horiike, S.5    Kashima, K.6
  • 2
    • 16944362760 scopus 로고    scopus 로고
    • Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia
    • Leukemia Study Group of the Ministry of Health and Welfare (Kohseisho)
    • Kiyoi, H and Naoe, T and Yokota, S and Nakao, M and Minami, S and Kuriyama, K and (1997) Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia. Leukemia Study Group of the Ministry of Health and Welfare (Kohseisho) Leukemia, 11, pp. 1447 - 1452.
    • (1997) Leukemia , vol.11 , pp. 1447-1452
    • Kiyoi, H.1    Naoe, T.2    Yokota, S.3    Nakao, M.4    Minami, S.5    Kuriyama, K.6
  • 3
    • 0035885955 scopus 로고    scopus 로고
    • The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
    • Kottaridis, P and Gale, R and Frew, M and Harrison, G and Langabeer, S and Belton, A and (2001) The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials Blood, 98, pp. 1752 - 1759.
    • (2001) Blood , vol.98 , pp. 1752-1759
    • Kottaridis, P.1    Gale, R.2    Frew, M.3    Harrison, G.4    Langabeer, S.5    Belton, A.6
  • 4
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of Flt3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
    • Thiede, C and Steudel, C and Mohr, B and Schaich, M and Schakel, U and Platzbecker, U and (2002) Analysis of Flt3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis Blood, 99, pp. 4326 - 4335.
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3    Schaich, M.4    Schakel, U.5    Platzbecker, U.6
  • 5
    • 0033758958 scopus 로고    scopus 로고
    • FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group
    • Abu-Duhier, F and Goodeve, A and Wilson, G and Gari, M and Peake, I and Rees, D and (2000) FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group Br J Haematol, 111, pp. 190 - 195.
    • (2000) Br J Haematol , vol.111 , pp. 190-195
    • Abu-Duhier, F.1    Goodeve, A.2    Wilson, G.3    Gari, M.4    Peake, I.5    Rees, D.6
  • 6
    • 0037061747 scopus 로고    scopus 로고
    • Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain
    • Kiyoi, H and Ohno, R and Ueda, R and Saito, H and Naoe, T. (2002) Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain Oncogene, 21, pp. 2555 - 2563.
    • (2002) Oncogene , vol.21 , pp. 2555-2563
    • Kiyoi, H.1    Ohno, R.2    Ueda, R.3    Saito, H.4    Naoe, T.5
  • 7
    • 0035892131 scopus 로고    scopus 로고
    • Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the Bcr-Abl b3a2 fusion protein
    • Clark, R and Dodi, I and Hill, S and Lill, J and Aubert, G and Macintyre, G and (2001) Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the Bcr-Abl b3a2 fusion protein Blood, 98, pp. 2887 - 2893.
    • (2001) Blood , vol.98 , pp. 2887-2893
    • Clark, R.1    Dodi, I.2    Hill, S.3    Lill, J.4    Aubert, G.5    Macintyre, G.6
  • 8
    • 0032005138 scopus 로고    scopus 로고
    • Dendritic cells stimulate the expansion of bcr-abl specific CD8+ T cells with cytotoxic activity against leukemic cells from patients with chronic myeloid leukemia
    • Nieda, M and Nicol, A and Kikuchi, A and Kashiwase, K and Taylor, K and Suzuki, K and (1998) Dendritic cells stimulate the expansion of bcr-abl specific CD8+ T cells with cytotoxic activity against leukemic cells from patients with chronic myeloid leukemia Blood, 91, pp. 977 - 983.
    • (1998) Blood , vol.91 , pp. 977-983
    • Nieda, M.1    Nicol, A.2    Kikuchi, A.3    Kashiwase, K.4    Taylor, K.5    Suzuki, K.6
  • 9
    • 0030946078 scopus 로고    scopus 로고
    • HLA-DR1-restricted bcr-abl (b3a2)-specific CD4+ T lymphocytes respond to dendritic cells pulsed with b3a2 peptide and antigen-presenting cells exposed to b3a2 containing cell lysates
    • Mannering, S and McKenzie, J and Fearnley, D and Hart, D. (1997) HLA-DR1-restricted bcr-abl (b3a2)-specific CD4+ T lymphocytes respond to dendritic cells pulsed with b3a2 peptide and antigen-presenting cells exposed to b3a2 containing cell lysates Blood, 90, pp. 290 - 297.
    • (1997) Blood , vol.90 , pp. 290-297
    • Mannering, S.1    McKenzie, J.2    Fearnley, D.3    Hart, D.4
  • 10
    • 0034161533 scopus 로고    scopus 로고
    • Vaccination of patients with chronic myelogenous leukemia with bcr-abl oncogen breakpoint fusion protein generates specific immune responses
    • Pinilla-Ibarz, J and Cathcart, K and Korontsvit, T and Soignet, S and Bocchia, M and Caggiano, J and (2000) Vaccination of patients with chronic myelogenous leukemia with bcr-abl oncogen breakpoint fusion protein generates specific immune responses Blood, 95, pp. 1781 - 1787.
    • (2000) Blood , vol.95 , pp. 1781-1787
    • Pinilla-Ibarz, J.1    Cathcart, K.2    Korontsvit, T.3    Soignet, S.4    Bocchia, M.5    Caggiano, J.6
  • 11
    • 0035094066 scopus 로고    scopus 로고
    • Dendritic-cell-peptide immunization provides immunoprotection against bcr-abl-positive leukemia in mice
    • He, L and Feng, H and Raymond, A and Kreeger, M and Zeng, Y and Graner, M and (2001) Dendritic-cell-peptide immunization provides immunoprotection against bcr-abl-positive leukemia in mice Cancer Immunol Immunother, 50, pp. 31 - 40.
    • (2001) Cancer Immunol Immunother , vol.50 , pp. 31-40
    • He, L.1    Feng, H.2    Raymond, A.3    Kreeger, M.4    Zeng, Y.5    Graner, M.6
  • 12
    • 0035138437 scopus 로고    scopus 로고
    • Mimotopes for tumor-specific T lymphocytes in human cancer determined with combinatorial peptide libraries
    • Linnemann, T and Tumenjargal, S and Gellrich, S and Wiesmuller, K and Kaltoft, K and Sterry, W and (2001) Mimotopes for tumor-specific T lymphocytes in human cancer determined with combinatorial peptide libraries Eur J Immunol, 31, pp. 156 - 165.
    • (2001) Eur J Immunol , vol.31 , pp. 156-165
    • Linnemann, T.1    Tumenjargal, S.2    Gellrich, S.3    Wiesmuller, K.4    Kaltoft, K.5    Sterry, W.6
  • 13
    • 0029043976 scopus 로고
    • Peptide binding to MHC class I molecules: Implications for antigenic peptide prediction
    • Parker, K and Shields, M and DiBrino, M and Brooks, A and Coligan, J. (1995) Peptide binding to MHC class I molecules: Implications for antigenic peptide prediction Immunol Res, 14, pp. 34 - 57.
    • (1995) Immunol Res , vol.14 , pp. 34-57
    • Parker, K.1    Shields, M.2    DiBrino, M.3    Brooks, A.4    Coligan, J.5
  • 14
    • 0028052724 scopus 로고
    • Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains
    • Parker, K and Bednarek, M and Coligan, J. (1994) Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains J Immunol, 152, pp. 163 - 175.
    • (1994) J Immunol , vol.152 , pp. 163-175
    • Parker, K.1    Bednarek, M.2    Coligan, J.3
  • 15
    • 0037356948 scopus 로고    scopus 로고
    • Expression of human leucocyte antigens and co-stimulatory molecules on blasts of patients with acute myeloid leukaemia
    • Vollmer, M and Li, L and Schmitt, A and Greiner, J and Reinhardt, P and Ringhoffer, M and (2003) Expression of human leucocyte antigens and co-stimulatory molecules on blasts of patients with acute myeloid leukaemia Br J Haematol, 120, pp. 1000 - 1008.
    • (2003) Br J Haematol , vol.120 , pp. 1000-1008
    • Vollmer, M.1    Li, L.2    Schmitt, A.3    Greiner, J.4    Reinhardt, P.5    Ringhoffer, M.6
  • 16
    • 0036129764 scopus 로고    scopus 로고
    • Loss or downregulation of HLA class I expression at the allelic level in acute leukemia is infrequent but functionally relevant, and can be restored by interferon
    • Brouwer, R and van der Heiden, P and Schreuder, G and Mulder, A and Datema, G and Anholts, J and (2002) Loss or downregulation of HLA class I expression at the allelic level in acute leukemia is infrequent but functionally relevant, and can be restored by interferon Hum Immunol, 63, pp. 200 - 210.
    • (2002) Hum Immunol , vol.63 , pp. 200-210
    • Brouwer, R.1    van der Heiden, P.2    Schreuder, G.3    Mulder, A.4    Datema, G.5    Anholts, J.6
  • 17
    • 23944452058 scopus 로고    scopus 로고
    • Targeted immunotherapy in acute myeloblastic leukemia: From animals to humans
    • Robin, M and Schlageter, M and Chomienne, C and Padua, R. (2005) Targeted immunotherapy in acute myeloblastic leukemia: From animals to humans Cancer Immunol Immunother, 54, pp. 933 - 943.
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 933-943
    • Robin, M.1    Schlageter, M.2    Chomienne, C.3    Padua, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.