Loss or downregulation of HLA class I expression at the allelic level in acute leukemia is infrequent but functionally relevant, and can be restored by interferon

Human Immunology

Volumn 63, Issue 3, 2002, Pages 200-210

  Brouwer, Rolf E ^a   Van Der Heiden, Pim ^a   Schreuder, Geziena M T ^b   Mulder, Arend ^b,c   Datema, Gert ^b   Anholts, Jacqy D H ^b   Willemze, Roel ^a   Claas, Frans H J ^b   Falkenburg, J H Frederik ^a,b  

^a Lab of Experimental Hematology   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c SVM Foundation for the Advancement of Public Health and Environmental Protection   (Netherlands)

Author keywords

Acute leukemia; Flow cytometry; Loss of HLA class I expression; Monoclonal antibodies; T cell recognition

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; INTERFERON; MONOCLONAL ANTIBODY;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; BLAST CELL; CELL MEDIATED LYMPHOLYSIS; CELL SURFACE; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DOWN REGULATION; FLOW CYTOMETRY; HLA TYPING; HUMAN; HUMAN CELL; IMMUNOSURVEILLANCE; LEUKEMIA REMISSION; PRIORITY JOURNAL;

EID: 0036129764     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(01)00381-0     Document Type: Article

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