Mimotopes for tumor-specific T lymphocytes in human cancer determined with combinatorial peptide libraries

European Journal of Immunology

Volumn 31, Issue 1, 2001, Pages 156-165

  Linnemann, Thomas ^a   Tumenjargal, Sherev ^a   Gellrich, Sylke ^a   Wiesmüller, Karl Heinz ^b   Kaltoft, Keld ^c   Sterry, Wolfram ^a   Walden, Peter ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b EMC MICROCOLLECTIONS GMBH   (Germany)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

Combinatorial peptide chemistry; Cutaneous lymphoma; T cell epitope; Tumor immunology; Tumor associated antigen

Indexed keywords

EPITOPE; HLA ANTIGEN; HLA B8 ANTIGEN; PEPTIDE LIBRARY; TUMOR ANTIGEN;

ANTIGEN RECOGNITION; ARTICLE; CELL ISOLATION; CELL SPECIFICITY; COMBINATORIAL LIBRARY; CONTROLLED STUDY; CYTOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE CLONE; PRIORITY JOURNAL; SKIN LYMPHOMA; TUMOR ASSOCIATED LEUKOCYTE; TUMOR IMMUNOLOGY; VACCINATION;

AMINO ACID SEQUENCE; ANTIGENS, NEOPLASM; CD8-POSITIVE T-LYMPHOCYTES; COMBINATORIAL CHEMISTRY TECHNIQUES; EPITOPES, T-LYMPHOCYTE; HLA-A1 ANTIGEN; HLA-B8 ANTIGEN; HUMANS; LYMPHOMA, T-CELL, CUTANEOUS; MOLECULAR SEQUENCE DATA;

EID: 0035138437     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200101)31:1<156::AID-IMMU156>3.0.CO;2-P     Document Type: Article

References (32)

1. Tumor antigens recognized by T lymphocytes
2. Heterogeneous expression of the tumor-associated antigens RAGE-1, PRAME, and glycoprotein 75 in human renal cell carcinoma: Candidates for T-cell-based immunotherapies?
3. Tumor-specific peptides in cutaneous T-cell lymphoma: Association with class I major histocompatibility complex and possible derivation from the clonotypic T-cell receptor
4. Direct identification of major histocompatibility complex class I-bound tumor-associated peptide antigens of a renal carcinoma cell line by a novel mass spectrometric method
5. Cloning and in vitro expression of a melanoma-associated antigen immunogenic in patients with melanoma
6. Toward a genetic analysis of tumor rejection antigens
7. Identification of genes coding for tumor antigens recognized by cytolytic T lymphocytes
8. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides
9. T-cell epitope mapping by flow cytometry
10. Random peptide libraries as tools in basic and applied immunology
11. Elucidation of T-cell epitopes: A synthetic approach with random peptide libraries
12. T-cell epitope determination
13. Determination of T cell epitopes with random peptide libraries
14. Cutaneous T cell lymphoma: Mycosis fungoides, Sezary syndrome, and other variants
15. Report of the symposium on Cutaneous Lymphomas: Sixth International Conference on Malignant Lymphoma
16. The Revised European-American Classification of Lymphoid Neoplasms (REAL): A new perspective for the classification of cutaneous lymphomas
17. Mycosis fungoides: Epidemilogic observations
18. Chemistry of peptides associated with MHC class I and class II molecules
19. Establishment of two continuous T-cell strains from a single plaque of a patient with mycosis fungoides
20. MHC ligands and peptide motifs
21. The Bw4/Bw6 difference between HLA-B*0802 and HLA-B*0801 changes the peptides endogenously bound and the stimulation of alloreactive T cells
22. Use of combinatorial peptide libraries to construct functional mimics of tumor epitopes recognized by MHC class Irestricted cytolytic T lymphocytes
23. + T cell epitopes with dedicated synthetic peptide libraries
24. Specificity and degeneracy of minor histocompatibility antigen-specific MHC-restricted CTL
25. Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone
26. The use of dedicated peptide libraries permits the discovery of high affinity binding peptides
27. Molecular basis for the recognition of two structurally different major histocompatibility complex/peptide complexes by a single T-cell receptor
28. Decrypting the structure of major histocompatibility complex class I-restricted cytotoxic T lymphocyte epitopes with complex peptide libraries
29. A molecular basis for how a single TCR interfaces multiple ligands
30. Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells
31. Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients