메뉴 건너뛰기




Volumn 71, Issue 4, 2006, Pages 479-485

ZD6474 inhibits proliferation and invasion of human hepatocellular carcinoma cells

Author keywords

Biological therapies; Extracellular matrix proteins; Hepatocellular carcinoma; Invasion; Laminin 5; Proliferation; Vascular endothelial growth factor receptor; ZD6474

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; KALININ; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SCLEROPROTEIN; VANDETANIB;

EID: 30444451162     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.11.005     Document Type: Article
Times cited : (44)

References (38)
  • 1
    • 0033799722 scopus 로고    scopus 로고
    • Estimating future hepatitis C morbidity, mortality, and costs in the United States
    • J.B. Wong, G.M. McQuillan, J.G. McHutchison, and T. Poynard Estimating future hepatitis C morbidity, mortality, and costs in the United States Am J Public Health 90 2000 1562 1569
    • (2000) Am J Public Health , vol.90 , pp. 1562-1569
    • Wong, J.B.1    McQuillan, G.M.2    McHutchison, J.G.3    Poynard, T.4
  • 2
    • 0024450697 scopus 로고
    • Prevalence of antibodies to hepatitis C virus in Italian patients with hepatocellular carcinoma [see comments]
    • M. Colombo, G. Kuo, Q.L. Choo, M.F. Donato, E. Del Ninno, and M.A. Tommasini Prevalence of antibodies to hepatitis C virus in Italian patients with hepatocellular carcinoma [see comments] Lancet 2 1989 1006 1008
    • (1989) Lancet , vol.2 , pp. 1006-1008
    • Colombo, M.1    Kuo, G.2    Choo, Q.L.3    Donato, M.F.4    Del Ninno, E.5    Tommasini, M.A.6
  • 6
    • 0034693799 scopus 로고    scopus 로고
    • The protein tyrosine kinase family of the human genome
    • D.R. Robinson, Y.M. Wu, and S.F. Lin The protein tyrosine kinase family of the human genome Oncogene 19 2000 5548 5557
    • (2000) Oncogene , vol.19 , pp. 5548-5557
    • Robinson, D.R.1    Wu, Y.M.2    Lin, S.F.3
  • 7
    • 0034219429 scopus 로고    scopus 로고
    • Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues
    • R. Yamaguchi, H. Yano, Y. Nakashima, S. Ogasawara, K. Higaki, and J. Akiba Expression and localization of vascular endothelial growth factor receptors in human hepatocellular carcinoma and non-HCC tissues Oncol Rep 7 2000 725 729
    • (2000) Oncol Rep , vol.7 , pp. 725-729
    • Yamaguchi, R.1    Yano, H.2    Nakashima, Y.3    Ogasawara, S.4    Higaki, K.5    Akiba, J.6
  • 8
    • 0033918376 scopus 로고    scopus 로고
    • Detection of vascular endothelial growth factor and its receptor expression in human hepatocellular carcinoma biopsy specimens
    • T. Shimamura, S. Saito, K. Morita, T. Kitamura, M. Morimoto, and T. Kiba Detection of vascular endothelial growth factor and its receptor expression in human hepatocellular carcinoma biopsy specimens J Gastroenterol Hepatol 15 2000 640 646
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. 640-646
    • Shimamura, T.1    Saito, S.2    Morita, K.3    Kitamura, T.4    Morimoto, M.5    Kiba, T.6
  • 9
    • 0038176090 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor tyrosine kinase inhibitors: PTK787/ZK 222584
    • A.L. Thomas, B. Morgan, J. Drevs, C. Unger, B. Wiedenmann, and U. Vanhoefer Vascular endothelial growth factor receptor tyrosine kinase inhibitors: PTK787/ZK 222584 Semin Oncol 30 2003 32 38
    • (2003) Semin Oncol , vol.30 , pp. 32-38
    • Thomas, A.L.1    Morgan, B.2    Drevs, J.3    Unger, C.4    Wiedenmann, B.5    Vanhoefer, U.6
  • 10
    • 0037102369 scopus 로고    scopus 로고
    • ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration
    • S.R. Wedge, D.J. Ogilvie, M. Dukes, J. Kendrew, R. Chester, and J.A. Jackson ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration Cancer Res 62 2002 4645 4655
    • (2002) Cancer Res , vol.62 , pp. 4645-4655
    • Wedge, S.R.1    Ogilvie, D.J.2    Dukes, M.3    Kendrew, J.4    Chester, R.5    Jackson, J.A.6
  • 11
    • 0037386774 scopus 로고    scopus 로고
    • Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase
    • F. Ciardiello, R. Caputo, V. Damiano, R. Caputo, T. Troiani, and D. Vitagliano Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase Clin Cancer Res 9 2003 1546 1556
    • (2003) Clin Cancer Res , vol.9 , pp. 1546-1556
    • Ciardiello, F.1    Caputo, R.2    Damiano, V.3    Caputo, R.4    Troiani, T.5    Vitagliano, D.6
  • 12
    • 21244488907 scopus 로고    scopus 로고
    • ZD6474 - Clinical experience to date
    • J.V. Heymach ZD6474 - clinical experience to date Br J Cancer 92 Suppl. 1 2005 S14 S20
    • (2005) Br J Cancer , vol.92 , Issue.1 SUPPL.
    • Heymach, J.V.1
  • 13
    • 2542556259 scopus 로고    scopus 로고
    • Involvement of the vascular endothelial growth factor receptor-1 in murine hepatocellular carcinoma development
    • H. Yoshiji, S. Kuriyama, J. Yoshii, Y. Ikenaka, R. Noguchi, and K. Yanase Involvement of the vascular endothelial growth factor receptor-1 in murine hepatocellular carcinoma development J Hepatol 41 2004 97 103
    • (2004) J Hepatol , vol.41 , pp. 97-103
    • Yoshiji, H.1    Kuriyama, S.2    Yoshii, J.3    Ikenaka, Y.4    Noguchi, R.5    Yanase, K.6
  • 14
    • 0034858098 scopus 로고    scopus 로고
    • Biological and clinical relevance of Laminin-5 in cancer
    • G. Giannelli, and S. Antonaci Biological and clinical relevance of Laminin-5 in cancer Clin Exp Metastasis 18 2001 439 443
    • (2001) Clin Exp Metastasis , vol.18 , pp. 439-443
    • Giannelli, G.1    Antonaci, S.2
  • 15
    • 0141679409 scopus 로고    scopus 로고
    • Laminin-5 chains are expressed differentially in metastatic and nonmetastatic hepatocellular carcinoma
    • G. Giannelli, E. Fransvea, C. Bergamini, F. Marinosci, and S. Antonaci Laminin-5 chains are expressed differentially in metastatic and nonmetastatic hepatocellular carcinoma Clin Cancer Res 9 2003 3684 3691
    • (2003) Clin Cancer Res , vol.9 , pp. 3684-3691
    • Giannelli, G.1    Fransvea, E.2    Bergamini, C.3    Marinosci, F.4    Antonaci, S.5
  • 16
    • 0034614939 scopus 로고    scopus 로고
    • Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5
    • N. Koshikawa, G. Giannelli, V. Cirulli, K. Miyazaki, and V. Quaranta Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5 J Cell Biol 148 2000 615 624
    • (2000) J Cell Biol , vol.148 , pp. 615-624
    • Koshikawa, N.1    Giannelli, G.2    Cirulli, V.3    Miyazaki, K.4    Quaranta, V.5
  • 18
    • 0035044816 scopus 로고    scopus 로고
    • Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion
    • G. Giannelli, C. Bergamini, E. Fransvea, F. Marinosci, V. Quaranta, and S. Antonaci Human hepatocellular carcinoma (HCC) cells require both alpha3beta1 integrin and matrix metalloproteinases activity for migration and invasion Lab Invest 81 2001 613 627
    • (2001) Lab Invest , vol.81 , pp. 613-627
    • Giannelli, G.1    Bergamini, C.2    Fransvea, E.3    Marinosci, F.4    Quaranta, V.5    Antonaci, S.6
  • 21
    • 0345375552 scopus 로고    scopus 로고
    • The effect of gefitinib (Iressa ZD1839) in combination with oxaliplatin is schedule-dependent in colon cancer cell lines
    • J.M. Xu, A. Azzariti, G. Colucci, and A. Paradiso The effect of gefitinib (Iressa ZD1839) in combination with oxaliplatin is schedule-dependent in colon cancer cell lines Cancer Chemother Pharmacol 52 2003 442 448
    • (2003) Cancer Chemother Pharmacol , vol.52 , pp. 442-448
    • Xu, J.M.1    Azzariti, A.2    Colucci, G.3    Paradiso, A.4
  • 22
    • 0041976904 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the interaction between ZD1839 ('Iressa') and cisplatin/5-fluorouracil
    • N. Magne, J.L. Fischel, C. Tiffon, P. Formento, A. Dubreuil, and N. Renee Molecular mechanisms underlying the interaction between ZD1839 ('Iressa') and cisplatin/5-fluorouracil Br J Cancer 89 2003 585 592
    • (2003) Br J Cancer , vol.89 , pp. 585-592
    • Magne, N.1    Fischel, J.L.2    Tiffon, C.3    Formento, P.4    Dubreuil, A.5    Renee, N.6
  • 23
    • 0037386939 scopus 로고    scopus 로고
    • Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase a antisense causes cooperative antitumor and antiangiogenic effect
    • G. Tortora, R. Caputo, V. Damiano, D. Melisi, R. Bianco, and G. Fontanini Combination of a selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase A antisense causes cooperative antitumor and antiangiogenic effect Clin Cancer Res 9 2003 1566 1572
    • (2003) Clin Cancer Res , vol.9 , pp. 1566-1572
    • Tortora, G.1    Caputo, R.2    Damiano, V.3    Melisi, D.4    Bianco, R.5    Fontanini, G.6
  • 24
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • P. Carmeliet Angiogenesis in health and disease Nat Med 9 2003 653 660
    • (2003) Nat Med , vol.9 , pp. 653-660
    • Carmeliet, P.1
  • 25
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • N. Ferrara, H.P. Gerber, and J. LeCouter The biology of VEGF and its receptors Nat Med 9 2003 669 676
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    Lecouter, J.3
  • 26
    • 0035003384 scopus 로고    scopus 로고
    • Structure and function of VEGF/VEGF-receptor system involved in angiogenesis
    • M. Shibuya Structure and function of VEGF/VEGF-receptor system involved in angiogenesis Cell Struct Funct 26 2001 25 35
    • (2001) Cell Struct Funct , vol.26 , pp. 25-35
    • Shibuya, M.1
  • 27
    • 0034693879 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis
    • M.J. Karkkainen, and T.V. Petrova Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis Oncogene 19 2000 5598 5605
    • (2000) Oncogene , vol.19 , pp. 5598-5605
    • Karkkainen, M.J.1    Petrova, T.V.2
  • 28
  • 29
    • 15044351008 scopus 로고    scopus 로고
    • Regulation of tumor cell motility by ERK mitogen-activated protein kinases
    • E. Viala, and J. Pouyssegur Regulation of tumor cell motility by ERK mitogen-activated protein kinases Ann N Y Acad Sci 1030 2004 208 218
    • (2004) Ann N Y Acad Sci , vol.1030 , pp. 208-218
    • Viala, E.1    Pouyssegur, J.2
  • 30
    • 11244275453 scopus 로고    scopus 로고
    • Laminin-5 offsets the efficacy of gefitinib ('Iressa') in hepatocellular carcinoma cells
    • G. Giannelli, A. Azzariti, E. Fransvea, L. Porcelli, S. Antonaci, and A. Paradiso Laminin-5 offsets the efficacy of gefitinib ('Iressa') in hepatocellular carcinoma cells Br J Cancer 91 2004 1964 1969
    • (2004) Br J Cancer , vol.91 , pp. 1964-1969
    • Giannelli, G.1    Azzariti, A.2    Fransvea, E.3    Porcelli, L.4    Antonaci, S.5    Paradiso, A.6
  • 31
    • 0037437146 scopus 로고    scopus 로고
    • Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution
    • S. Schenk, E. Hintermann, M. Bilban, N. Koshikawa, C. Hojilla, and R. Khokha Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution J Cell Biol 161 2003 197 209
    • (2003) J Cell Biol , vol.161 , pp. 197-209
    • Schenk, S.1    Hintermann, E.2    Bilban, M.3    Koshikawa, N.4    Hojilla, C.5    Khokha, R.6
  • 32
    • 30444445564 scopus 로고    scopus 로고
    • Sequence-dependent antiproliferative effects of cytotoxic drugs and epidermal growth factor receptor inhibitors
    • M.P. Morelli, T. Cascone, T. Troiani, F. De Vita, M. Orditura, and G. Laus Sequence-dependent antiproliferative effects of cytotoxic drugs and epidermal growth factor receptor inhibitors Ann Oncol 16 Suppl. 4 2005 iv61 iv68
    • (2005) Ann Oncol , vol.16 , Issue.4 SUPPL.
    • Morelli, M.P.1    Cascone, T.2    Troiani, T.3    De Vita, F.4    Orditura, M.5    Laus, G.6
  • 33
    • 11144231663 scopus 로고    scopus 로고
    • Combination antiangiogenic and androgen deprivation therapy for prostate cancer: A promising therapeutic approach
    • B. Nicholson, K. Gulding, M. Conaway, S.R. Wedge, and D. Theodorescu Combination antiangiogenic and androgen deprivation therapy for prostate cancer: a promising therapeutic approach Clin Cancer Res 10 2004 8728 8734
    • (2004) Clin Cancer Res , vol.10 , pp. 8728-8734
    • Nicholson, B.1    Gulding, K.2    Conaway, M.3    Wedge, S.R.4    Theodorescu, D.5
  • 34
    • 11244327801 scopus 로고    scopus 로고
    • Identification of RET kinase inhibitors as potential new treatment for sporadic and inherited thyroid cancer
    • F. Carlomagno, and M. Santoro Identification of RET kinase inhibitors as potential new treatment for sporadic and inherited thyroid cancer J Chemother 16 Suppl. 4 2004 49 51
    • (2004) J Chemother , vol.16 , Issue.4 SUPPL. , pp. 49-51
    • Carlomagno, F.1    Santoro, M.2
  • 35
    • 21244475061 scopus 로고    scopus 로고
    • ZD6474 - Novel inhibitor of VEGFR and EGFR tyrosine kinase activity
    • A.J. Ryan, and S.R. Wedge ZD6474 - novel inhibitor of VEGFR and EGFR tyrosine kinase activity Br J Cancer 92 Suppl. 1 2005 S6 S13
    • (2005) Br J Cancer , vol.92 , Issue.1 SUPPL.
    • Ryan, A.J.1    Wedge, S.R.2
  • 36
    • 11144223542 scopus 로고    scopus 로고
    • ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: Schedule-dependent enhancement of antitumor activity
    • K.J. Williams, B.A. Telfer, S. Brave, J. Kendrew, L. Whittaker, and I.J. Stratford ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: schedule-dependent enhancement of antitumor activity Clin Cancer Res 10 2004 8587 8593
    • (2004) Clin Cancer Res , vol.10 , pp. 8587-8593
    • Williams, K.J.1    Telfer, B.A.2    Brave, S.3    Kendrew, J.4    Whittaker, L.5    Stratford, I.J.6
  • 37
    • 19944430364 scopus 로고    scopus 로고
    • Antitumor activity of ZD6474, a vascular endothelial growth factor-2 and epidermal growth factor receptor small molecule tyrosine kinase inhibitor, in combination with SC-236, a cyclooxygenase-2 inhibitor
    • C. Tuccillo, M. Romano, T. Troiani, E. Martinelli, F. Morgillo, and F. De Vita Antitumor activity of ZD6474, a vascular endothelial growth factor-2 and epidermal growth factor receptor small molecule tyrosine kinase inhibitor, in combination with SC-236, a cyclooxygenase-2 inhibitor Clin Cancer Res 11 2005 1268 1276
    • (2005) Clin Cancer Res , vol.11 , pp. 1268-1276
    • Tuccillo, C.1    Romano, M.2    Troiani, T.3    Martinelli, E.4    Morgillo, F.5    De Vita, F.6
  • 38
    • 4444347110 scopus 로고    scopus 로고
    • Disruption of hepatocellular tight junctions by vascular endothelial growth factor (VEGF): A novel mechanism for tumor invasion
    • M. Schmitt, A. Horbach, R. Kubitz, A. Frilling, and D. Haussinger Disruption of hepatocellular tight junctions by vascular endothelial growth factor (VEGF): a novel mechanism for tumor invasion J Hepatol 41 2004 274 283
    • (2004) J Hepatol , vol.41 , pp. 274-283
    • Schmitt, M.1    Horbach, A.2    Kubitz, R.3    Frilling, A.4    Haussinger, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.