Magnetic resonance angiography and vascular corrosion casting as tools in biomedical research: Application to transgenic mice modeling Alzheimer's disease

Neurological Research

Volumn 26, Issue 5, 2004, Pages 507-516

  Krucker, Thomas ^a   Schuler, Alexandra ^b   Meyer, Eric P ^b   Staufenbiel, Matthias ^c   Beckmann, Nicolau ^c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Alzheimer's disease; Angiopathy; Cerebral amyloid angiopathy (CAA); Circle of Willis; Magnetic resonance angiography (MRA); Magnetic resonance imaging (MRI); Vascular corrosion cast

Indexed keywords

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; BRAIN CIRCULUS ARTERIOSUS; CONTROLLED STUDY; HISTOLOGY; MAGNETIC RESONANCE ANGIOGRAPHY; MEDICAL RESEARCH; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; TECHNIQUE; TRANSGENIC MOUSE; VASCULAR AMYLOIDOSIS; VASCULAR DISEASE; WILD TYPE;

AGING; ALZHEIMER DISEASE; ANIMALS; CEREBRAL AMYLOID ANGIOPATHY; CEREBRAL ARTERIAL DISEASES; CEREBRAL ARTERIES; CORROSION CASTING; DISEASE MODELS, ANIMAL; MAGNETIC RESONANCE ANGIOGRAPHY; MICE; MICE, TRANSGENIC;

EID: 3042856760     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164104225016281     Document Type: Article

References (64)

1. de la Torre JC, Mussivand T. Can disturbed brain microcirculation cause Alzheimer's disease? Neurol Res 1993; 15: 146-153
2. Taylor SF, Tandon R, Koeppe RA. Global cerebral blood flow increase reveals focal hypoperfusion in schizophrenia. Neuropsychopharmacology 1999; 21: 368-371
3. Vaiva G, Cottencin O, Llorca PM, et al. Regional cerebral blood flow in deficit/nondeficit types of schizophrenia according to SDS criteria. Prog Neuropsychopharmacol Biol Psychiatry 2002; 26: 481-485
4. Wehrli FW, Shimakawa A, Gullberg GT, et al. Time-of-flight MR flow imaging: Selective saturation recovery with gradient refocusing. Radiology 1986; 160: 781-785
5. Gullberg GT, Wehrli FW, Shimakawa A, et al. MR vascular imaging with a fast gradient refocusing pulse sequence and reformatted images from transaxial sections. Radiology 1987; 165: 241-246
6. Frahm J, Haase A, Matthaei D. Rapid NMR imaging of dynamic processes using the FLASH technique. Magn Reson Med 1986; 3: 321-327
7. Laub GA, Kaiser WA. MR angiography with gradient motion refocusing. J Comput Assist Tomogr 1988; 12: 377-382
8. Haacke EM, Masaryk TJ, Wielopolski PA, et al. Optimizing blood vessel contrast in fast three-dimensional MRI. Magn Reson Med 1990; 14: 202-221
9. Kobayashi H, Kawamoto S, Saga T, et al. Micro-MR angiography of normal and intratumoral vessels in mice using dedicated intravascular MR contrast agents with high generation of polyamidoamine dendrimer core: Reference to pharmacokinetic properties of dendrimer-based MR contrast agents. J Magn Reson Imaging 2001; 14: 705-713
10. Fink C, Kiessling F, Bock M, et al. High-resolution three-dimensional MR angiography of rodent tumors: Morphologic characterization of intratumoral vasculature. J Magn Reson Imaging 2003; 18: 59-65
11. Wehr S, Rudin M, Joergensen J, et al. Allo- and autotransplantation of carotid artery - a new model of chronic graft vessel disease. Transplantation 1997; 64: 20-27
12. Reese T, Bochelen D, Sauter A, et al. Magnetic resonance angiography of the rat cerebrovascular system without the use of contrast agents. NMR Biomed 1999; 12: 189-196
13. Beckmann N, Stirnimann R, Bochelen D. High resolution magnetic resonance angiography of the mouse brain: Application to murine focal cerebral ischemia models. J Magn Reson 1999; 140: 442-450
14. Beckmann N. High resolution magnetic resonance angiography non-nvasively reveals mouse strain differences in the cerebrovascular anatomy, in vivo. Magn Reson Med 2000; 44: 252-258
15. Besselmann M, Liu M, Diedenhofen M, et al. MR angiographic investigation of transient focal cerebral ischemia in rat. NMR Biomed 2001; 14: 289-296
16. Beckmann N, Schuler A, Müggler T, et al. Age-dependent cerebrovascular abnormalities and blood flow disturbances in APP23 mice modelling Alzheimer's disease. J Neurosci 2003; 23: 8453-8459
17. Mellin AF, Cofer GP, Smith BR, et al. Three dimensional magnetic resonance microangiography of rat neurovasculature. Magn Reson Med 1994; 32: 199-205
18. Nowell JA, Pangborn J, Tyler WS. Scanning electron microscopy of the avain lung. Scanning Electron Microsc 1970; Pt 1: 249-256
19. Murakami T. Application of the scanning electron microscope to the study of the fine distribution of the blood vessels. Arch Histol Jpn 1971; 32: 445-454
20. Lametschwandtner A, Lametschwandtner U, Weiger T. Scanning electron microscopy of vascular corrosion casts - technique and applications: updated review. Scanning Microsc 1990; 4: 889-940
21. Konerding MA. Scanning electron microscopy of corrosion casting in medicine. Scanning Microsc 1991; 5: 851-865
22. Hossler FE, Douglas JE. Vascular corrosion casting: Review of advantages and limitations in the application of some simple quantitative methods. Microsc Microanal 2001; 7: 253-264
23. Krucker T, Siggins GR, Halpain S. Dynamic actin filaments are required for stable long-term potentiation (LTP) in area CA1 of the hippocampus. Proc Natl Acad Sci USA 2000; 97: 6856-6861
24. Krucker T, Siggins GR, McNamara RK, et al. Targeted disruption of RC3 reveals a calmodulin-based mechanism for regulating metaplasticity in the hippocampus. J Neurosci 2002; 22: 5525-5535
25. Lametschwandtner A, Lametschwandtner U, Weiger T. Scanning electron microscopy of vascular corrosion casts - technique and applications. Scan Electron Microsc 1984; Pt 2: 663-695
26. Miodonski A, Kus J, Tyrankiewicz R. In: Dido JA, Motta PM, Allen DJ, eds. Three Dimensional Microanatomy of Cells and Tissue Surfaces, London: Elsevier, 1981: pp. 71-78
27. Minnich B, Lametschwandtner A. Lengths measurements in microvascular corrosion castings: Two-dimensional versus three-dimensional morphometry. Scanning 2000; 22: 173-177
28. Minnich B, Leeb H, Bernroider EWN, Lametschwandtner A. Three-dimensional morphometry in scanning electron microscopy: a technique for accurate dimensional and angular measurements of microstructures using stereopaired digitized images and digital image analysis. J Microsc 1999; 195: 23-33
29. Müller R, Matter S, Neuenschwander P, et al. 3D micro tomographic imaging and quantitative morphometry for the nondestructive evaluation of porous biomaterials. In: Briber R, Pfeiffer DG, Han CC, eds. Morphological Control in Multiphase Polymer Mixtures, Vol. 461, Mat Res Soc Proc 1996; 461: 217-222
30. Stampanoni M, Borchert G, Wyss P, et al. High resolution X-ray detector for synchrotron-based microtomography. Nucl Inst Meth A 2002; 491: 291-301
31. Snowdon DA, Greiner LH, Mortimer JA, et al. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA 1997; 277: 813-817
32. Sparks DL. Coronary artery disease, hypertension, ApoE, and cholesterol: a link to Alzheimer's disease? Ann NY Acad Sci 1997; 826: 128-146
33. Grammas P. A damaged microcirculation contributes to neuronal cell death in Alzheimer's disease. Neurobiol Aging 2000; 21: 199-205
34. Gilbert JJ, Vinters HV. Cerebral amyloid angiopathy: incidence and complications in the aging brain. I. Cerebral hemorrhage. Stroke 1983; 14: 915-923
35. Staufenbiel M, Sommer B. Transgenic animal models in the development of therapeutic strategies for Alzheimer's disease. In: Haass C, ed. Molecular Biology of Alzheimer's Disease: Genes and Mechanisms Involved in Amyloid Generation, New York: Harwood Academic Publishers, 1998: pp. 309-326
36. Sturchler-Pierrat C, Abramowski D, Duke M, et al. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc Natl Acad Sci USA 1997; 94: 13287-13292
37. Calhoun ME, Burgermeister P, Phinney AL, et al. Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid. Proc Natl Acad Sci USA 1999; 96: 14088-14093
38. Sturchler-Pierrat C, Staufenbiel M. Pathogenic mechanisms of Alzheimer's disease analyzed in the APP23 transgenic mouse model. Ann NY Acad Sci 2000; 920: 134-139
39. Winkler DT, Bondolfi L, Herzig MC, et al. Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy. J Neurosci 2001; 21: 1619-1627
40. Probst A, Langui D, Ulrich J. Alzheimer's disease: A description of the structural lesions. Brain Pathol 1991; 1: 229-239
41. Franceschi M, Alberoni M, Bressi S, et al. Correlations between cognitive impairment, middle cerebral artery flow velocity and cortical glucose metabolism in the early phase of Alzheimer's disease. Dementia 1995; 6: 32-38
42. Ishibashi K, Tanaka K, Nakabayashi T, Nakamura M, Uchiyama M, Okawa M. Latent cerebral artery stenoses on magnetic resonance angiography in a patient diagnosed as probable Alzheimer disease. Psychiatry Clin Neurosci 1998; 52: 93-96
43. Hsia AY, Masliah E, McConlogue L, et al. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc Natl Acad Sci USA 1999; 96: 3228-3233
44. Moechars D, Dewachter I, Lorent K, et al. Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain. J Biol Chem 1999; 274: 6483-6492
45. Kumar-Singh S, Dewachter I, Moechars D, et al. Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation. Neurobiol Dis 2000; 7: 9-22
46. Hassler O. Arterial deformities in senile brains. The occurrence of the deformities in a large autopsy series and some aspects of their functional significance. Acta Neuropathol (Berl) 1967; 8: 219-29
47. Scheibel AB, Duong T, Tmiyasu U. The Biological Substrates of Alzheimer's Disease, New York: Academic Press, 1986: pp. 77-192
48. Ravens JR. In: Cervos-Navarro J, ed. Pathology of Cerebrospinal Microcirculation, New York: Raven Press, 1978: pp. 487-501
49. Burgermeister P, Calhoun ME, Winkler DT, et al. Mechanisms of cerebrovascular amyloid deposition. Lesson from mouse models. Ann NY Acad Sci 2000; 903: 307-316
50. Hardy JA, Higgins GA. Alzheimer's disease: The amyloid cascade hypothesis. Science 1992; 256: 184-185
51. Klein WL, Krafft GA, Finch CE. Targeting small Aβ oligomers: The solution to an Alzheimer's disease conundrum? Trends Neurosci 2001; 24: 219-224
52. Kirkitadze MD, Bitan G, Teplow DB. Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies. J Neurosci Res 2002; 69: 567-577
53. Selkoe DJ. Alzheimer's disease is a synaptic failure. Science 2002; 298: 789-791
54. Thomas T, Thomas G, McLendon C, et al. Beta-amyloid-mediated vasoactivity and vascular endothelial damage. Nature 1996; 380: 168-171
55. Townsend KP, Obregon D, Quadros A, et al. Proinflammatory and vasoactive effects of Abeta in the cerebrovasculature. Ann NY Acad Sci 2002; 977: 65-76
56. Paris D, Humphrey J, Quadros A, et al. Vasoactive effects of Aβ in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: Role of inflammation. Neurol Res 2003; 25: 642-651
57. Arendash GW, Su GC, Crawford FC, et al. Intravascular beta-amyloid infusion increases blood pressure: Implications for a vasoactive role of beta-amyloid in the pathogenesis of Alzheimer's disease. Neurosci Lett 1999; 268: 17-20
58. Niwa K, Porter VA, Kazama K, et al. Abeta-peptides enhance vasoconstriction in cerebral circulation. Am J Physiol Heart Circ Physiol 2001; 281: H2417-H2424
59. Price JM, Sutton ET, Hellermann A, et al. Beta-amyloid induces cerebrovascular endothelial dysfunction in the rat brain. Neurol Res 1997; 19: 534-538
60. Price JM, Chi X, Hellermann G, et al. Physiological levels of beta-amyloid induce cerebral vessel dysfunction and reduce endothelial nitric oxide production. Neurol Res 2001; 23: 506-512
61. Aliev G, Seyidova D, Neal ML, et al. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice. Ann N Y Acad Sci 2002; 977: 45-64
62. Ferreiro JA, Ansbacher LE, Vinters HV. Stroke related to cerebral amyloid angiopathy: The significance of systemic vascular disease. J Neurol 1989; 236: 267-272
63. Roher AE, Esh C, Kokjohn TA, et al. Circle of willis atherosclerosis is a risk factor for sporadic Alzheimer's disease. Arterioscler Thromb Vasc Biol 2003; 23: 2055-2062
64. Thal DR, Ghebremedhin E, Orantes M, et al. Vascular pathology in Alzheimer disease: correlation of cerebral amyloid angiopathy and arteriosclerosis/lipohyalinosis with cognitive decline. J Neuropathol Exp Neurol 2003; 62: 1287-1301