Repair of potentially lethal damage does not depend on functional TP53 in human glioblastoma cells

Radiation Research

Volumn 161, Issue 5, 2004, Pages 511-516

  Van Bree, C ^a   Franken, N A P ^a   Rodermond, H M ^a   Stalpers, L J A ^a   Haveman, J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PROTEIN P21; PROTEIN P53; DNA;

AGED; ARTICLE; CANCER CELL CULTURE; CASE REPORT; CDKN1A GENE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL DAMAGE; CELL PROLIFERATION; CELL SURVIVAL; CLONOGENESIS; CONTROLLED STUDY; FLOW CYTOMETRY; GAMMA IRRADIATION; GENE; GENE EXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN CELL; MALE; POTENTIALLY LETHAL DAMAGE; PRIORITY JOURNAL; RADIOSENSITIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; APOPTOSIS; CELL DIVISION; DNA DAMAGE; DNA REPAIR; METABOLISM; PATHOLOGY; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; TUMOR CELL LINE;

APOPTOSIS; CELL DIVISION; CELL LINE, TUMOR; DNA; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; GLIOBLASTOMA; HUMANS; RADIATION DOSAGE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 3042845763     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/3154     Document Type: Article

References (26)

1. R. A. Phillips and L. J. Tolmach, Repair of potentially lethal damage in x-irradiated HeLa cells. Radiat. Res. 29, 413-432 (1966).
2. R. R. Weichselbaum, J. B. Little and J. Nove, Response of human osteosarcoma in vitro to irradiation: Evidence for unusual cellular repair activity. Int. J. Radiat. Biol. 31, 295-299 (1977).
3. M. Guichard, R. R. Weichselbaum, J. B. Little and E. P. Malaise, Potential lethal damage as a possible determinant of human tumor radiosensitivity. Radiother. Oncol. 1, 263-267 (1984).
4. G. W. Barendsen, C. van Bree and N. A. P. Franken, Importance of cell proliferative state and potentially lethal damage repair on radiation effectiveness: implications for combined tumor treatments. Int. J. Oncol. 19, 247-256 (2001).
5. A. F. Hermens and G. W. Barendsen, The proliferative status and clonogenic capacity of tumour cells in a transplantable rhabdomyosarcoma of the rat before and after irradiation with 800 rad of X-rays. Cell Tissue Kinet. 11, 83-100 (1978).
6. S. Masunaga, K. Ono, H. Hori, M. Suzuki, Y. Kinashi, M. Takagaki, S. Kasai, H. Nagasawa and Y. Uto, Potentially lethal damage repair by total and quiescent tumor cells following various DNA-damaging treatments. Radiat. Med. 17, 259-264 (1999).
7. R. R. Weichselbaum, J. Nove and J. B. Little, Deficient recovery from potentially lethal radiation damage in ataxia telangiectasia and xeroderma pigmentosum. Nature 271, 261-262 (1978).
8. J. L. Schwartz, J. Rasey, L. Wiens, R. Jordan and K. J. Russell, Functional inactivation of p53 by HPV-E6 transformation is associated with a reduced expression of radiation-induced potentially lethal damage. Int. J. Radiat. Biol. 75, 285-291 (1999).
9. J. L. Schwartz, R. Jordan, W. K. Kaufmann, J. Rasey, K. J. Russell and R. R. Weichselbaum, Evidence for the expression of radiation-induced potentially lethal damage being a p53-dependent process. Int. J. Radiat. Biol. 76, 1037-1043 (2000).
10. N. A. P. Franken, C. van Bree, R. ten Cate, C. H. van Oven and J. Haveman, Importance of TP53 and RB in the repair of potentially lethal damage and induction of color junctions after exposure to ionizing radiation. Radiat. Res. 158, 707-714 (2002).
11. J. B. Little, H. Nagasawa, W. K. Dahlberg, M. Z. Zdzienicka, S. Burma and D. J. Chen, Differing responses of Nijmegen breakage syndrome and ataxia telangiectasia cells to ionizing radiation. Radiat. Res. 158, 319-326 (2002).
12. T. D. Kessis, R. J. Slebos, W. G. Nelson, M. B. Kastan, B. S. Plunkett, S. M. Han, A. T. Lorincz, L. Hedrick and K. R. Cho, Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. Proc. Natl. Acad. Sci. USA 90, 3988-3992 (1993).
13. R. J. Slebos, M. H. Lee, B. S. Plunkett, T. D. Kessis, B. O. Williams, T. Jacks, L. Hedrick, M. B. Kastan and K. R. Cho, p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc. Natl. Acad. Sci. USA 91, 5320-5324 (1994).
14. D. A. Haas-Kogan, S. S. Kogan, G. Yount, J. Hsu, M. Haas, D. F. Deen and M. A. Israel, p53 function influences the effect of fractionated radiotherapy on glioblastoma tumors. Int. J. Radiat. Oncol. Biol. Phys. 43, 399-403 (1999).
15. M. C. Hulshof, R. W. Koot, E. C. Schimmel, F. Dekker, D. A. Bosch and D. Gonzalez Gonzalez, Prognostic factors in glioblastoma multiforme. 10 years experience of a single institution. Strahlenther. Onkol. 177, 283-290 (2001).
16. A. Taghian, H. Suit, F. Pardo, D. Gioioso, K. Tomkinson, W. DuBois and L. Gerweck, In vitro intrinsic radiation sensitivity of glioblastoma multiforme. Int. J. Radiat. Oncol. Biol. Phys. 23, 55-62 (1992).
17. A. Taghian, J. Ramsay, J. Allalunis-Turner, W. Budach, D. Gioioso, F. Pardo, P. Okunieff, N. Bleehen, R. Urtasun and H. Suit, Intrinsic radiation sensitivity may not be the major determinant of the poor clinical outcome of glioblastoma multiforme. Int. J. Radiat. Oncol. Biol. Phys. 25, 243-249 (1993).
18. F. Fehlauer, A. D. Barten-Van Rijbroek, L. J. Stalpers, S. Leenstra, J. Lindeman, I. Tjahja, D. Troost, J. G. Wolbers, P. van der Valk and P. Sminia, Additive cytotoxic effect of cisplatin and X-irradiation on human glioma cell cultures derived from biopsy-tissue. J. Cancer Res. Clin. Oncol. 126, 711-716 (2000).
19. B. Gerlach, A. H. Harder, T. J. Hulsebos, S. Leenstra, B. J. Slotman, W. P. Vandertop, K. A. Hartmann and P. Sminia, Radiosensitivity and TP53, EGFR amplification and LOH10 analysis of primary glioma cell cultures. Strahlenther. Onkol. 178, 491-496 (2002).
20. H. J. Bernsen, P. F. Rijken, H. Peters, J. A. Raleigh, J. W. Jeuken, P. Wesseling and A. J. van der Kogel, Hypoxia in a human intracerebral glioma model. J. Neurosurg. 93, 449-454 (2000).
21. R. R. Weichselbaum, A. Schmit and J. B. Little, Cellular repair factors influencing radiocurability of human malignant tumors. Br. J. Cancer 45, 10-14 (1982).
22. P. Heller and G. P. Raaphorst, Inhibition of potentially lethal damage recovery by altered pH, glucose utilization and proliferation in plateau growth phase human glioma cells. Int. J. Radiat. Biol. 66, 41-47 (1994).
23. K. Webley, J. A. Bond, C. J. Jones, J. P. Blaydes, A. Craig, T. Hupp and D. Wynford-Thomas, Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage. Mol. Cell. Biol. 20, 2803-2808 (2000).
24. S. Leenstra, E. K. Bijlsma, D. Troost, J. Oosting, A. Westerveld, D. A. Bosch and T. J. Hulsebos, Allele loss on chromosomes 10 and 17p and epidermal growth factor receptor gene amplification in human malignant astrocytoma related to prognosis. Br. J. Cancer 70, 684-689 (1994).
25. V. Gudkov and E. A. Komarova, The role of p53 in determining sensitivity to radiotherapy. Nat. Rev. Cancer 3, 117-129 (2003).
26. J. Dahm-Daphi, P53: Biology and role for cellular radiosensitivity. Strahlenther. Onkol. 176, 278-285 (2000).