Advances in the search for Psoriasis susceptibility genes

Molecular Genetics and Metabolism

Volumn 71, Issue 1-2, 2000, Pages 250-255

  Capon, Francesca ^a   Dallapiccola, Bruno ^b   Novelli, Giuseppe ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Complex diseases; HLA; Psoriasis; Susceptibility loci

Indexed keywords

CHROMOSOME 17Q; CHROMOSOME 6P; DISEASE ASSOCIATION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE MAPPING; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HLA SYSTEM; HUMAN; PRIORITY JOURNAL; PSORIASIS; SHORT SURVEY;

EID: 0033814264     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1006/mgme.2000.3031     Document Type: Article

References (34)

1. The pathophysiology of psoriasis
2. Epidemiology of psoriasis: Clinical issues
3. Epidemiology: Natural history and genetic
4. Trigger factors in psoriasis
5. Psoriasis in monozygotic twins: Variations in expression in individuals with identical genetic constitution
6. Psoriasis in Autralian twins
7. Of genes and antigens: The inheritance of psoriasis
8. Localization of psoriasis susceptibility locus PSORS1 to a 60 kilobase interval telomeric to HLA-C
9. Gene for familial psoriasis susceptibility mapped to the distal end of chromosome 17q
10. Confirmation of genetic heterogeneity in familial psoriasis
11. Evidence that a locus for familial psoriasis maps to chromosome 4q
12. Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis
13. Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan
14. Searching for psoriasis susceptibility genes in Italy: Genome scan and evidence for a new locus to chromosome 1q
15. The genetics of psoriasis: A complex disorder of the skin and immune system
16. Analysis of three suggested psoriasis susceptibility loci in a large swedish set of families: Confirmation of linkage to chromosome 6p (HLA region), and to 17q, but not to 4q
17. Psoriasis susceptibility locus in chromosome region 3q21 identified in patients from southwest Sweden
18. Evidence for interaction between psoriasis susceptibility loci om chromosomes 6p21 and 1q21
19. Characterization of the major suscpetibility region for psoriasis at chromosome 6p21.3
20. Association analysis using refined microsatellite markers localizes a susceptibility locus for psoriasis vulgaris within a 111kb segment telomeric to the HLA-C gene
21. Complete sequence and gene map of a human major histocompatibility complex: The MHC sequencing consortium
22. New major histocompatibility complex genes
23. Fine mapping of the PSORS4 psoriasis susceptibility region on chromosome 1q21
24. Molecules in focus: Psoriasin (S100A7)
25. Genomic structure, promoter characterisation and mutational analysis of the S100A7 gene: Exclusion of a candidate for familial psoriasis susceptibility
26. Identification in the HLA class I region of a gene expressed late in keratinocyte differentiation
27. Genetic polymorphisms in the keratin-like S gene within the human major histocompatibility complex and association analysis on the susceptibility to psoriasis vulgaris
28. A non-HLA gene within the MHC in psoriasis
29. Corneodesmosin gene polymorphism demonstrates strong linkage disequilibrium with HLA and association with posriasis vulgaris
30. Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis
31. S gene (corneodesmosin) diversity and its relationship to psoriasis: High content of cSNP in the HLA-linked S gene
32. A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele