The nucleophilic addition of α-metallated 1,3-dioxanes to planar chiral cationic η3-allylmolybdenum complexes. Synthesis of (2E,5S,6R,7E)-6-methyl-8-phenylocta-2,7-dienoic acid methyl ester, a key component of the Cryptophycins

Organic and Biomolecular Chemistry

Volumn 2, Issue 12, 2004, Pages 1719-1731

  Cooksey, John ^a   Gunn, Andrew ^a   Kocienski, Philip J ^a   Kuhl, Alexander ^b   Uppal, Sukhjinder ^a   Christopher, John A ^b,c   Bell, Richard ^c  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLUMN CHROMATOGRAPHY; COMPLEXATION; ESTERS; ISOMERIZATION; ISOMERS; MOLYBDENUM; ORGANIC ACIDS; OXIDATION; POSITIVE IONS; PRECIPITATION (CHEMICAL); PROTONS; SPECTROSCOPIC ANALYSIS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

CRYPTOPHYCINS; NUCLEOPHILIC ADDITION; SHARPLESS KINETIC RESOLUTION; STEREOSELECTIVE APPENDAGE;

ORGANOMETALLICS;

ALLYL COMPOUND; ANTINEOPLASTIC AGENT; CATION; COPPER; CRYPTOPHYCIN; CYCLOPEPTIDE; DEPSIPEPTIDE; DIOXANE DERIVATIVE; ESTER; MOLYBDENUM; ORGANOMETALLIC COMPOUND;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; OXIDATION REDUCTION REACTION; STEREOISOMERISM; SYNTHESIS;

ALLYL COMPOUNDS; ANTINEOPLASTIC AGENTS; CATIONS; COPPER; DEPSIPEPTIDES; DIOXANES; ESTERS; MOLECULAR STRUCTURE; MOLYBDENUM; ORGANOMETALLIC COMPOUNDS; OXIDATION-REDUCTION; PEPTIDES, CYCLIC; STEREOISOMERISM;

EID: 3042841597     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b400242c     Document Type: Article

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