Activation and induction of cyclic AMP phosphodiesterase (PDE4) in rat pulmonary microvascular endothelial cells

Biochemical Pharmacology

Volumn 68, Issue 3, 2004, Pages 479-491

  Zhu, Bing ^a   Kelly, John ^a,b   Vemavarapu, Lakshmi ^a   Thompson, W Joseph ^a   Strada, Samuel J ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

6 MB cAMP; cyclic AMP dependent protein kinase; N6 monobutyryl cAMP; PDEs; phosphodiesterases; PKA; rat pulmonary microvascular endothelial cells; RFM; rolipram and forskolin medium; RPMVECs; TM PI

Indexed keywords

BUTYRYL CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME ACTIVATOR; FORSKOLIN; PHOSPHODIESTERASE IV; ROLIPRAM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; EXPERIMENTAL RAT; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; IN VITRO STUDY; LUNG ENDOTHELIUM; MICROVASCULARIZATION; NONHUMAN; PRIORITY JOURNAL; RAT; WESTERN BLOTTING;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BUCLADESINE; CYCLIC AMP; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; FORSKOLIN; IMMUNOHISTOCHEMISTRY; LUNG; PHOSPHODIESTERASE INHIBITORS; PHOSPHORYLATION; RATS; RNA, MESSENGER; ROLIPRAM;

EID: 3042819132     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.03.039     Document Type: Article

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