Regulation of cyclic AMP in rat pulmonary microvascular endothelial cells by rolipram-sensitive cyclic AMP phosphodiesterase (PDE4)

Biochemical Pharmacology

Volumn 63, Issue 4, 2002, Pages 797-807

  Thompson, W Joseph ^a,b   Ashikaga, Takashi ^a   Kelly, John J ^a   Liu, Li ^a   Zhu, Bing ^a   Vemavarapu, Lakshimi ^a   Strada, Samuel J ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b Cell Pathways Inc   (United States)

Author keywords

Cyclic AMP metabolism; Cyclic nucleotide phosphodiesterase; Endothelial cell permeability; Phosphodiesterease inhibitors; Rolipram; Signal transduction

Indexed keywords

ADENINE; ADENOSINE DERIVATIVE; ADENYLATE CYCLASE; CYCLIC AMP; FORSKOLIN; ISOPRENALINE; ISOPROTEIN; MESSENGER RNA; PHOSPHODIESTERASE IV; ROLIPRAM;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG SENSITIVITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; HYDROLYSIS; LUNG BLOOD VESSEL; LUNG INJURY; NONHUMAN; NUCLEIC ACID METABOLISM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, ION EXCHANGE; CYCLIC AMP; DRUG INTERACTIONS; ENDOTHELIUM, VASCULAR; FORSKOLIN; ISOPROTERENOL; LUNG; PHOSPHODIESTERASE INHIBITORS; RATS; ROLIPRAM; TIME FACTORS;

EID: 0037085012     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00914-5     Document Type: Article

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