Acute neurosteroid modulation and subunit isolation of the γ-aminobutyric acidA receptor in the bullfrog, Rana catesbeiana

Journal of Molecular Endocrinology

Volumn 32, Issue 3, 2004, Pages 921-934

  Hollis, D M ^a,b   Goetz, F W ^a,d   Roberts, S B ^a,c   Boyd, S K ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b OREGON STATE UNIVERSITY   (United States)

^c MARINE BIOLOGICAL LABORATORY   (United States)

^d UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; COMPLEMENTARY DNA; DNA FRAGMENT; ISOPROTEIN; MUSCIMOL; NEUROSTEROID; NEUROTRANSMITTER; PREGNENOLONE SULFATE; RECEPTOR SUBUNIT;

ANIMAL BEHAVIOR; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOSE TIME EFFECT RELATION; FROG; ISOTOPE LABELING; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN ISOLATION; RECEPTOR BINDING; REGULATORY MECHANISM; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANESTHETICS; ANIMALS; BRAIN; CELL MEMBRANE; CLONING, MOLECULAR; GABA AGONISTS; MALE; MOLECULAR SEQUENCE DATA; MUSCIMOL; PREGNANOLONE; PREGNENOLONE; PROTEIN ISOFORMS; PROTEIN SUBUNITS; RADIOLIGAND ASSAY; RANA CATESBEIANA; RECEPTORS, GABA-A; SEQUENCE ALIGNMENT; TRITIUM;

EID: 3042815953     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0320921     Document Type: Article

References (96)

1. Adjeroud S, Tonon MC, Lamacz M, Leneveu E, Stoeckel ME, Tappaz ML, Cazin L, Danger JM, Bernard C & Vaudry H 1986 GABA-ergic control of alpha-melanocyte-stimulating hormone (α-MSH) release by frog neurointermediate lobe in vitro. Brain Research Bulletin 17 717-723.
2. Akk G, Bracamontes J & Steinbach JH 2001 Pregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunit. Journal of Physiology 532 673-684.
3. Akwa Y, Young J, Kabbadj K, Sancho MJ, Zucman D, Vourc'h C, Jung-Testas I, Hu ZY, Le Goascogne C & Jo DH 1991 Neurosteroids: biosynthesis, metabolism and function of pregnenolone and dehydroepiandrosterone in the brain. Journal of Steroid Biochemistry and Molecular Biology 40 71-81.
4. A receptor complex β 2/3 subunits in the brain of the frog Rana pipiens. Neuroscience Letters 225 65-68.
5. Aller MI, Paniagua MA, Pollard S, Stephenson FA & Fernandez-Lopez A 2003 The GABA(A) receptor complex in the chicken brain: immunocytochemical distribution of alpha 1- and gamma 2-subunits and autoradiographic distribution of BZ1 and BZ2 binding sites. Journal of Chemical Neuroanatomy 25 1-18.
6. A receptor needs two homologous domains of the β-subunit for activation by GABA but not by pentobarbital. Nature 366 565-569.
7. Antal M 1991 Distribution of GABA immunoreactivity in the optic tectum of the frog: a light and electron microscopic study. Neuroscience 42 879-891.
8. Anzelius M, Ekstrom P, Mohler H & Richards JG 1995 Immunocytochemical localization of Gaba(a) receptor beta(2)/beta(3)-subunits in the brain of Atlantic salmon (Salmo salar L). Journal of Chemical Neuroanatomy 8 207-221.
9. Barale E, Fasolo A, Girardi E, Artero C, & Franzoni MF 1996 Immunohistochemical investigation of gamma-aminobutyric acid ontogeny and transient expression in the central nervous system of Xenopus laevis tadpoles. Journal of Comparative Neurology 368, 285-294.
10. A receptor: the receptor/channel superfamily. Trends in Neuroscience 10 502-509.
11. Baulieu EE 1997 Neurosteroids: of the nervous system, by the nervous system, for the nervous system. Recent Progress in Hormone Research 52 1-32.
12. Baulieu EE 1998 Neurosteroids: a novel function of the brain. Pychoneuroendocrinology 23 963-987.
13. Beaujean D, Mensah-Nyagan AG, Do-Rego J-L, Luu-The V, Pelletier G & Vaudry H 1999 Immunocytochemical localization and biological activity of hydroxysteroid sulfotransferase in the frog brain. Journal of Neurochemistry 72 848-857.
14. A receptor: evidence for a b-strand. Journal of Neuroscience 19 4847-4854.
15. Boyd SK & Moore FL 1990 Evidence for GABA involvement in stress-induced inhibition of male amphibian sexual behavior. Hormones and Behavior 24 128-138.
16. A receptor subtypes: from pharmacology to molecular biology. FASEB Journal 5 2916-2923.
17. Chang Y & Weiss DS 2000 Functional domains of GABA receptors. In GABA in the Nervous System: The View at Fifty Years, pp 127-139. Eds DL Martin & RW Olsen. Philadelphia, PA: Lippencott Williams & Wilkins.
18. Chomczynski P 1993 A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques 15 532-534, 536-537.
19. Chomczynski P & Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Analytical Biochemistry 162 156-159.
20. Compagnone NA & Mellon SH 2000 Neurosteroids: biosynthesis and function of these novel neuromodulators. Frontiers in Neuroendocrinology 21 1-56.
21. Do-Rego JL, Mensah-Nyagans AG, Feuilloley M, Ferrara P, Pelletier G & Vaudry H 1998 The endozepine triakontatetraneuropeptide diazepam-binding inhibitor [17-50] stimulates neurosteroid biosynthesis in the frog hypothalamus. Neuroscience 83 555-570.
22. Duchamp-Viret P, Duchamp A & Chaput M 1993 GABAergic control of odor-induced activity in the frog olfactory bulb: electrophysiological study with picrotoxin and bicuculline. Neuroscience 53 111-120.
23. Endepols H, Walkowiak W & Luksch H 2000 Chemoarchitecture of the anuran auditory midbrain. Brain Research Reviews 33 179-198.
24. Enna SJ & Snyder SH 1977 GABA receptor binding in frog spinal cord and brain. Journal of Neurochemistry 28 857-860.
25. Findlay GS, Ueno S, Harrison NL & Harris RA 2000 Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors (corrected). Neuroscience Letters 293 155-158.
26. Franzoni MF & Morino P 1989 The distribution of GABA-like-immunoreactive neurons in the brain of the newt, Triturus cristatus carnifex, and the green frog, Rana esculenta. Cell and Tissue Research 255 155-166.
27. A receptor complex in rat cortex. European Journal of Pharmacology 288 157-162.
28. A receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement. Neuropharmacology 42 502-521.
29. Hamilton KA 1992 Distribution of immunoreactivity for gamma-aminobutyric acid in the salamander olfactory bulb. Journal of Comparative Neurology 319 606-614.
30. A receptors by neuroactive steroids. European Journal of Pharmacology 289 249-257.
31. Hauser CA, Wetzel CH, Berning B, Gerner FM & Rupprecht R 1997 Flunitrazepam has an inverse agonistic effect on recombinant alpha6 beta2 gamma2-GABAA receptors via a flunitrazepam-binding site. Journal of Biological Chemistry 272 11723-11727.
32. Hollis DM & Boyd SK 2003 Characterization of the GABA(A) receptor in the brain of the adult male bullfrog, Rana catesbeiana. Brain Research 992 69-75.
33. Jimenez AJ, Aller MI, Martin R, Perez-Martin M, Perez-Figares JM, Fernandez-Lopez A & Fernandez-Llebrez P 2000 The subcommissural organ of the frog Rana perezi is innervated by nerve fibres containing GABA. Cell and Tissue Research 299 253-262.
34. A receptors. Neuron 3 745-753.
35. Knapp RJ, Malatynska E & Yamamura HI 1990 From binding studies to the molecular biology of GABA receptors. Neurochemical Research 15 105-112.
36. Kratskin I, Kenigfest N, Reperant J, Rio JP & Vesselkin N 1992 Presumptive GABAergic feedback input to the frog olfactory bulb: a double labeling study with retrograde axonal tracing and GABA immunohistochemistry. Brain Research 581 171-174.
37. A receptor function. Trends in Pharmacological Sciences 16 295-303.
38. A receptor. In Neurosteroids: A New Regulatory Function in the Nervous System, pp 125-142. Eds E-E Baulicu, P Robel & M Schumacher. Totowa, NJ: Humana Press, Inc.
39. Lan NC, Chen JS, Belelli D, Pritchett DB, Seeburg PH & Gee KW 1990 A steroid recognition site is functionally coupled to an expressed GABA(A)-benzodiazepine receptor. European Journal of Pharmacology 188 403-406.
40. Le Foll F, Louiset E, Castel H, Vaudry H & Cazin L 1997 Electrophysiological effects of various neuroactive steroids on the GABA(A) receptor in pituitary melanotrope cells. European Journal of Pharmacology 331 303-311.
41. A receptor phosphorylation: multiple sites, actions and artifacts. Trends in Pharmacological Sciences 12 84-87.
42. Li Z & Fite KV 1998 Distribution of GABA-like immunoreactive neurons and fibers in the central visual nuclei and retina of the frog, Rana pipiens. Visual Neuroscience 15 995-1006.
43. Li Z & Fite KV 2001 GABAergic visual pathways in the frog Rana pipiens. Visual Neuroscience 18 457-464.
44. Lin WY & Feng AS 2003 GABA is involved in spatial unmasking in the frog auditory midbrain. Journal of Neuroscience 23 8143-8151.
45. A receptor. FEBS Letters 246 145-148.
46. 3H]muscimol binding to brain synaptic membranes by progesterone and related pregnanes. European Journal of Pharmacology 176 297-303.
47. Louiset E, McKernan R, Sieghart W & Vauchy H 2000 Subunit composition and pharmacological characterization of γ-aminobutyric acid type A receptors in frog pituitary melanotrophs. Endocrinology 141 1083-1092.
48. Majewska MD & Schwartz RD 1987 Pregnenolone-sulfate: an endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain? Brain Research 404 355-360.
49. A receptors in brain. Brain Research 339 178-182.
50. A receptor. European Journal of Pharmacology 189 307-315.
51. A receptor. Journal of Neuroscience 10 2330-2337.
52. A receptor in rat brain. FEBS Letters 260 261-265.
53. Mazda GY, Nistri A & Sivilotti L 1990 The effect of GABA on the frog optic tectum is sensitive to ammonium and to penicillin. European Journal of Pharmacology 179 111-118.
54. A receptors by 5α-pregnan-3α -ol-20-one in the rat brain regions. Brain Research 832 164-167.
55. Mensah-Nyagan AG, Feuilloley M, Dupont E, Do-Rego JL, Leboulenger F, Pelletier G & Vaudry H 1994 Immunocytochemical localization and biological activity of 3-β-hydroxysteroid dehydrogenase in the central nervous system of the frog. Journal of Neuroscience 14 7306-7318.
56. Mensah-Nyagan AG, Beaujean D, Do-Rego JL, Mathieu M, Vallarino M, Luu-The V, Pelletier G & Vaudry H 2000 In vivo evidence for the production of sulfated steroids in the frog brain. Comparative Biochemistry and Physiology B-Biochemistry and Molecular Biology 126 213-219.
57. Mensah-Nyagan AG, Do-Rego JL, Beaujean D, Luu-The V, Pelletier G & Vaudry H 2001a Regulation of neurosteroid biosynthesis in the frog diencephalon by GABA and endozepines. Hormones and Behavior 40 218-225.
58. Mensah-Nyagan AG, Beaujean D, Luu-The V, Pelletier G & Vaudry H 2001b Anatomical and biochemical evidence for the synthesis of unconjugated and sulfated neurosteroids in amphibians. Brain Research Reviews 37 13-24.
59. Miller S, Janin J, Lesk AM & Chothia C 1987 Interior and surface of monomeric proteins. Journal of Molecular Biology 196 641-656.
60. Mok WM & Krieger NR 1990 Evidence that 5α-pregnan-3α-ol-20-one is the metabolite responsible for progesterone anesthesia. Brain Research 533 42-45.
61. Mok WM & Krieger NR 1992 Steroid levels in tadpole (Rana catesbeiana) brain at the loss and return of the righting response. Pharmacology Biochemistry and Behavior 43 523-528.
62. Naujoks-Manteuffel C, Himstedt W & Glasener-Cipollone G 1994 Distribution of GABA-immunoreactive neurons, in the brain of adult and developing salamanders (Pleurodeles waltli,Triturus alpestris). Cell and Tissue Research 276 485-501.
63. A receptor determined by electron microscopic image analysis. Journal of Neuochemistry 62 815-818.
64. Newell JG, Davies M, Bateson AN & Dunn SM 2000 Tyrosine 62 of the γ-aminobutyric acid type A receptor β2 subunit is an important determinant of high affinity agonist binding. Journal of Biological Chemistry 275 14198-14204.
65. Nistri A & Sivilotti L 1985 An unusual effect of gamma-aminobutyric acid on synaptic transmission of frog tectal neurons in vitro. British Journal of Pharmacology 85 917-921.
66. A receptors. FASEB Journal 4 1469-1480.
67. A receptor family in the mammalian brain. Neurochemical Research 16 317-325.
68. A receptors in an amphibian brain. Brain Research 646 258-266.
69. Paul SM & Purdy RH 1992 Neuroactive steroids. FASEB Journal 6 2311-2322.
70. A receptor by depressant barbiturates and pregnane steroids. British Journal of Pharmacology 94 1257-1269.
71. A and glycine receptors expressed in Xenopus laevis oocytes: a comparative study. British Journal of Pharmacology 122 1707-1719.
72. Pollák E, Lazar G, Gabriel R & Wang SR 1999 Localization and source of gamma aminobutyric acid immunoreactivity in the isthmic nucleus of the frog Rana esculenta. Brain Research Bulletin 48 343-350.
73. A-benzodiazepine receptors produced in transfected cells. Science 245 1389-1392.
74. A receptor subunit for benzodiazepine pharmacology. Nature 338 582-585.
75. A receptors. Neuron 4 759-765.
76. Reichenberger I, Streit P, Otterson OP & Dierenger N 1993 GABA- and glycine-like immunoreactivities in the cerebellum of the frog. Neuroscience Letters 154 89-92.
77. Roberts SB, Langenau DM & Goetz FW 2000 Cloning and characterization of prostaglandin endoperoxide synthase-1 and -2 from the brook trout ovary. Molecular and Cellular Endocrinology 160 89-97.
78. Rybicka KK & Udin SB 1994 Ultrastructure and GABA immunoreactivity in layers 8 and 9 of the optic tectum of Xenopus laevis. European Journal of Neuroscience 6 1567-1582.
79. Salpeter MM & Loring RH 1985 Nicotinic acetylcholine receptors in vertebrate muscle: properties, distribution, and neural control. Progress in Neurobiology 25 297-325.
80. A/benzodiazepine receptors using radioligands and monoclonal antibodies. Brain Research 473 314-320.
81. Shen W, Mennerick S, Zorumski EC, Covey DF & Zorumski CF 1999 Pregnenolone sulfate and dehydroepiandrosterone sulfate inhibit GABA-gated chloride currents in Xenopus oocytes expressing picrotoxin-insensitive GABA(A) receptors. Neuropharmacology 38 267-271.
82. A receptor on the response to a neurosteroid. Eurepean Journal of Pharmacology 206 77-80.
83. A receptor channels. EMBO Journal 11 2017-2023.
84. Sivilotti L & Nistri A 1989 Pharmacology of a novel effect of γ-aminobutyric acid on the frog optic tectum in vitro. European Journal of Pharmacology 164 205-212.
85. Sivilotti L & Nistri A 1992 An intracellular study of the effects of GABA on frog tectoral neurons in vitro. Neuroscience Letters 145 28-32.
86. 3H] muscimol photoaffinity substrate in the bovine γ-aminobutyric acid A receptor α subunit. Journal of Biological Chemistry 269 20380-20387.
87. A receptors. Trends in Pharmacological Sciences 16 162-168.
88. Srinivasan S, Nichols CJ, Lawless GM, Olsen RW & Tobin AJ 1999 Two invariant tryptophans on the alphal subunit define domains necessary for GABA(A) receptor assembly. Journal of Biological Chemistry 274 26633-26638.
89. Takase M, Ukena K, Yamazaki T, Kominami S & Tsutsui K 1999 Pregnenolone, pregnenolone sulfate, and cytochrome P450 side-chain cleavage enzyme in the amphibian brain and their seasonal changes. Endocrinology 140 1936-1944.
90. A and benzodiazepine receptors in the brain of the frog, Rana esculenta. Brain Behavior and Evolution 42 171-177.
91. A receptors. In Ligand- and Voltage-Gated Ion Channels, pp 265-290, Ed. RA North. Boca Raton, FL: CRC Press Inc.
92. Watanabe M, Maemura K, Kanbara K, Tamayama T & Hayasaki H 2002 GABA and GABA receptors in the central nervous system and other organs. In International Review of Cytology: A Survey of Cell Biology, vol. 213, pp 1-47. Ed. KW Jeon. San Diego, CA: Academic Press.
93. A receptors is essential for benzodiazepine agonist binding. Journal of Biological Chemistry 267 1426-1429.
94. A receptor subtypes in the tiger salamander retina. Visual Neuroscience 8 57-64.
95. Zhang H, Xu J & Feng AS 1999 Effects of GABA-mediated inhibition on direction-dependent frequency tuning in the frog inferior colliculus. Journal of Comparative Physiology A-Sensory Neural and Behavioral Physiology 184 85-98.
96. Zheng W & Hall JC 2000 GABAergic inhibition shapes frequency tuning and modifies response properties in the superior olivary nucleus of the leopard frog. Journal of Comparative Physiology A-Sensory Neural and Behavioral Physiology 186 661-671.