A single amino acid substitution in a proteasome subunit triggers aggregation of ubiquitinated proteins in stressed neuronal cells

Journal of Neurochemistry

Volumn 90, Issue 1, 2004, Pages 19-28

  Li, Zongmin ^a   Arnaud, Lisette ^a   Rockwell, Patricia ^a   Figueiredo Pereira, Maria E ^a,b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Neurodegeneration; Oxidative stress; Proteasome; Synuclein; Ubiquitin

Indexed keywords

ALANINE; AMINO ACID; CELL PROTEIN; CHYMOTRYPSIN; PROTEASOME; PROTEASOME BETA5; SYNUCLEIN; THREONINE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENETIC MANIPULATION; HOMEOSTASIS; MOUSE; MUTATION; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; UBIQUITINATION;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CADMIUM; CELL LINE; CELL SURVIVAL; CYSTEINE ENDOPEPTIDASES; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION; MACROMOLECULAR SUBSTANCES; MICE; MULTIENZYME COMPLEXES; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; NEURONS; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS; PROTEINS; SYNUCLEINS; TRANSFECTION; UBIQUITIN;

ANIMALIA;

EID: 3042811126     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02456.x     Document Type: Article

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