Severe acute respiratory syndrome: Scientific and anecdotal evidence for drug treatment

Current Opinion in Investigational Drugs

Volumn 5, Issue 2, 2004, Pages 179-185

  Tsang, Kenneth ^a   Seto, Wing Hong ^a  

^a QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

Chinese medicine; Ribavirin; SARS CoV; Severe acute respiratory syndrome; Steroid

Indexed keywords

ANTIVIRUS AGENT; IMMUNOLOGICAL ADJUVANT;

ANIMAL; DRUG EFFECT; HUMAN; IMMUNOLOGY; REVIEW; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIVIRAL AGENTS; HUMANS; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME;

EID: 3042767980     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (49)

1. Zhong NS, Zeng GQ: Our strategies for fighting severe acute respiratory syndrome (SARS). Am J Respir Crit Care Med (2003) 168(1):7-9.
2. Seto WH, Tsang D, Yung RW, Ching TY, Ng TK, Ho M, Ho LM, Peiris JS; Advisors of Expert SARS Group of Hospital Authority: Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS). Lancet (2003) 361(9368):1519-1520.
3. Peiris JSM, Lai ST, Poon LLM, Guan Y, Yam LYC, Lim W, Nicholls J, Yee WKS, Yan WW, Cheung MT, Cheng VCC et al: Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet (2003) 361(9366):1319-1325.
4. Poutanen SM, Low DE, Henry B, Finkelstein S, Rose D, Green K, Tellier R, Draker R, Adachi D, Ayers M, Chan AK et al: Identification of severe acute respiratory syndrome in Canada. N Engl J Med (2003) 348(20):1995-2005.
5. Ksiazek TG, Erdman D, Goldsmith CS, Zaki SR, Peret T, Emery S, Tong S, Urbani C, Comer JA, Lim W, Rollin PE et al: A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med (2003) 348(20):1953-1966.
6. Drosten C, Gunther S, Preiser W, van der Werf S, Brodt HR, Becker S, Rabenau H, Panning M, Kolesnikova L, Fouchier RA, Berger A et al: Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med (2003) 348(20):1967-1976.
7. Guan Y, Zheng BJ, He YQ, Liu XL, Zhuang ZX, Cheung CL, Luo SW, Li PH, Zhang LJ, Guan YJ, Butt KM et al: Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China. Science (2003) 302(5643):276-278.
8. Enserink M: Infectious diseases: Singapore lab faulted in SARS case. Science (2003) 301(5641):1824.
9. World Health Organization: Disease outbreak reported: Acute respiratory syndrome in China-update 3. http://www.who.int/csr/don/2003- 2-20/en
10. Fouchier RA, Kuiken T, Schutten M, van Amerongen G, van Doornum GJ, van den Hoogen BG, Peiris M, Lim W, Stohr K, Osterhaus AD: Aetiology: Koch's postulates fulfilled for SARS virus. Nature (2003) 423(6937):240.
11. Nicholls JM, Poon LL, Lee KC, Ng WF, Lai ST, Leung CY, Chu CM, Hui PK, Mak KL, Lim W, Yan KW et al: Lung pathology of fatal severe acute respiratory syndrome. Lancet (2003) 361(9371):1773-1778.
12. Franks TJ, Chong PY, Chui P, Galvin JR, Lourens RM, Reid AH, Selbs E, McEvoy CP, Hayden CD, Fukuoka J, Taubenberger JK et al: Lung pathology of severe acute respiratory syndrome (SARS): A study of 8 autopsy cases from Singapore. Hum Pathol (2003) 34(8):743-748.
13. Ng ML, Tan SH, See EE, Ooi EE, Ling AE: Early events of SARS coronavirus infection in Vero cells. J Med Virol (2003) 71(3):323-331.
14. Tsang KW, Rutman A, Kanthakumar K, Belcher J, Lund V, Roberts DE, Read RC, Cole PJ, Wilson R: Haemophilus influenzae infection of human respiratory mucosa in low concentrations of antibiotics. Am Rev Respir Dis (1993) 148(1):201-207.
15. Tsang KW, Rutman A, Tanaka E, Lund V, Dewar A, Cole PJ, Wilson R: Interaction of Pseudomonas aeruginosa with human respiratory mucosa in vitro. Eur Respir J (1994) 7(10):1746-1753.
16. Tsang KW, Ho PL, Ooi GC, Yee WK, Wang T, Chan-Yeung M, Lam WK, Seto WH, Yam LY, Cheung TM, Wong PC et al: A cluster of cases of severe acute respiratory syndrome in Hong Kong. N Engl J Med (2003) 348(20):1977-1985.
17. Lee N, Hui D, Wu A, Chan P, Cameron P, Joynt GM, Ahuja A, Yung MY, Leung CB, To KF, Lui SF et al: A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med (2003) 348(20):1986-1994.
18. Booth CM, Matukas LM, Tomlinson GA, Rachlis AR, Rose DB, Dwosh HA, Walmsley SL, Mazzulli T, Avendano M, Derkach P, Ephtimios IE et al: Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. J Am Med Assoc (2003) 289(21):2801-2809.
19. Tsang KW, Mok TY, Wong PC, Ooi GC: Severe acute respiratory syndrome (SARS) in Hong Kong. Respirology (2003) 8(3):259-265.
20. Tsang KW, Lam WK: Management of severe acute respiratory syndrome: The Hong Kong University experience. Am J Respir Crit Care Med (2003) 168(4):417-424.
21. Ooi GC, Khong PL, Müller NL, Yiu WC, Zhou LJ, Ho JC, Lam B, Nicolaou S, Tsang KW: Temporal lung changes in SARS: Sequential thin-section CT findings in 30 patients. Radiology (2004): in press.
22. Ooi GC, Khong PL, Lam B, Ho JC, Yiu MW, Wong WM, Wang T, Ho PL, Wong PC, Lam WK, Lai KN et al: Relationship between radiological and clinical parameters in SARS. Radiology (2004): in press.
23. Wong WM, Ho JC, Ooi GC, Mok TY, Chan J, Hung IF, Ng W, Lam YM, Tam WO, Wong BC, Wong PC et al: Liver function abnormality correlates with disease activity and severity of severe acute respiratory syndrome. J Am Med Assoc (2004): in press.
24. Li SS, Cheng CW, Fu CL, Chan YH, Lee MP, Chan JW, Yiu SF: Left ventricular performance in patients with severe acute respiratory syndrome: A 30-day echocardiographic follow-up study. Circulation (2004) 108(15):1798-1803.
25. Chiu WK, Cheung PC, Ng KL, Ip PL, Sugunan VK, Luk DC, Ma LC, Chan BH, Lo KL, Lai WM: Severe acute respiratory syndrome in children: Experience in a regional hospital in Hong Kong. Pediatr Crit Care Med (2003) 4(3):279-283.
26. Hsu LY, Lee CC, Green JA, Ang B, Paton NI, Lee L, Villacian JS, Lim PL, Earnest A, Leo YS: Severe acute respiratory syndrome (SARS) in Singapore: Clinical features of index patient and initial contacts. Emerg Infect Dis (2003) 9(6):713-717.
27. Xiao Z, Li Y, Chen R, Li S, Zhong S, Zhong N: A retrospective study of 78 patients with severe acute respiratory syndrome. Chin Med J (2003) 116(6):805-810.
28. Lam MF, Ooi GC, Lam B, Ho JC, Seto WH, Ho PL, Wong PC, Liang R, Lam WK, Ip MS, Tsang KW: An indolent case of severe acute respiratory syndrome. Am J Respir Crit Care Med (2004) 169(1):125-128.
29. Ho JC, Ooi GC, Mok TY, Chan JW, Hung I, Lam B, Wong PC, Li PC, Ho PL, Lam WK, Ng CK et al: High dose pulse versus non-pulse corticosteroid regimens in severe acute respiratory syndrome. Am J Respir Crit Care Med (2003) 168(12):1449-1456.
30. Peiris JSM, Chu CM, Cheng VCC, Chan KS, Hung IFN, Poon LLM, Law KI, Tang BSF, Hon TYW, Chan CS, Chan KH et al: Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: A prospective study. Lancet (2003) 361(9371):1767-1772.
31. Wenzel RP, Edmond MB: Managing SARS amidst uncertainty. N Engl J Med (2003) 348(20):1947-1948.
32. Cyranoski D: Critics slam treatment for SARS as ineffective and perhaps dangerous. Nature (2003) 423(6935):4.
33. Anand K, Ziebuhr J, Wadhwani P, Mesters JR, Hilgenfeld R: Coronavirus main proteinase (3CLpro) structure: Basis for design of anti-SARS drugs. Science (2003) 300(5626):1763-1767.
34. Zeng FY, Chan CW, Chan MN, Chen JD, Chow KY, Hon CC, Hui KH, Li J, Li VY, Wang CY, Wang PY et al: The complete genome sequence of severe acute respiratory syndrome coronavirus strain HKU-39849 (HK-39). Exp Biol Med (2003) 228(7):866-873.
35. Bermejo-Martin JF, Jimenez JL, Munoz-Fernandez A: Pentoxifylline and severe acute respiratory syndrome (SARS): A drug to be considered. Med Sci Monit (2003) 9(6):SR29-SR34.
36. Cinatl J, Morgenstern B, Bauer G, Chandra P, Rabenau H, Doerr HW: Treatment of SARS with human interferons. Lancet (2003) 362(9380):293-294.
37. Cinatl J, Morgenstern B, Bauer G, Chandra P, Rabenau H, Doerr HW: Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Lancet (2003) 361(9374):2045- 2046.
38. Ota K: Review of ubenimex (Bestatin): Clinical research. Biomed Pharmacother (1991) 45(2-3):55-60.
39. Kontoyiannis DP, Pasqualini R, Arap W: Aminopeptidase N inhibitors and SARS. Lancet (2003) 361(9368):1558.
40. Tsang KW, Zhong NS: SARS: Pharmacotherapy. Respirology (2004) (Suppl): in press.
41. Cohen AJ, King TE Jr, Downey GP: Rapidly progressive bronchiolitis obliterans with organizing pneumonia. Am J Respir Crit Care Med (1994) 149(6):1670-1675.
42. Smego RA, Ahmed N: A systematic review of the adjunctive use of systemic corticosteroids for pulmonary tuberculosis. Int J Tuberc Lung Dis (2003) 7(3):208-213.
43. Pareja JG, Garland R, Koziel H: Use of adjunctive corticosteroids in severe adult non-HIV Pneumocystis carinii pneumonia. Chest (1998) 113(5):1215-1224.
44. Dwyer JM: Manipulating the immune system with immune globulin. N Engl J Med (1992) 326(2):107-116.
45. Samuelsson A, Towers TL, Ravetch JV: Anti-inflammatory activity of IVIg mediated through the inhibitory Fc receptor. Science (2001) 291(5503):484-486.
46. Rieben R, Roos A, Muizert Y, Tinguely C, Gerritsen AF, Daha MR: Immunoglobulin M-enriched human intravenous immunoglobulin prevents complement activation in vitro and in vivo in a rat model of acute inflammation. Blood (1999) 93(3):942-951.
47. Jia W, Gao W: Is traditional Chinese medicine useful in the treatment of SARS? Phytother Res (2003) 17(7):840-841.
48. Wu HJ, Zhao XY, Wang F: Clinical observation on treatment of 40 SARS uncertain patients with integrative traditional Chinese and Western medicine. Zhongguo Zhong Xi Yi Jie He Za Zhi (2003) 23(8):572-574.
49. De Groot AS: How the SARS vaccine effort can learn from HIV-speeding towards the future, learning from the past. Vaccine (2003) 21(27-28):4095-4104.