Human CD34+ hematopoietic progenitor cell-directed lentiviral-mediated gene therapy in a xenotransplantation model of lysosomal storage disease

Molecular Therapy

Volumn 9, Issue 6, 2004, Pages 856-865

  Hofling, A Alex ^a   Devine, Steven ^a   Vogler, Carole ^b   Sands, Mark S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

glucuronidase; Gene therapy; Lysosomal storage disease; Mucopolysaccharidosis VII; Xenotransplantation

Indexed keywords

BETA GLUCURONIDASE; CD34 ANTIGEN; COMPLEMENTARY DNA; LENTIVIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; BIOCHEMISTRY; BONE MARROW CELL; CELLULAR DISTRIBUTION; CELLULAR PARAMETERS; CLINICAL PROTOCOL; CONTROLLED STUDY; DRUG EFFICACY; ENZYME DEFICIENCY; GENETIC CODE; GENETIC TRANSDUCTION; HEMATOPOIETIC STEM CELL; HOST; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOID CELL; LYSOSOME STORAGE DISEASE; MOUSE; MUCOPOLYSACCHARIDOSIS TYPE 7; NONHUMAN; PROTEIN EXPRESSION; RECIPIENT; STEM CELL GENE THERAPY; STEM CELL MOBILIZATION; VIRUS GENOME; XENOTRANSPLANTATION;

ANIMALS; ANTIGENS, CD34; BONE MARROW; GENE THERAPY; GENETIC VECTORS; GLUCURONIDASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; LENTIVIRUS; MALE; MICE; MICE, KNOCKOUT; MUCOPOLYSACCHARIDOSIS VII; TISSUE DISTRIBUTION; TRANSDUCTION, GENETIC; TRANSPLANTATION, HETEROLOGOUS;

MURINAE;

EID: 3042731837     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.03.013     Document Type: Article

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