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Volumn 331, Issue 1, 2004, Pages 153-160

A one-step approach to obtain cell clones expressing tetracycline- responsive transactivators

Author keywords

Inducible expression; rtTA transactivator; Tetracycline; tTA transactivator

Indexed keywords

ANTIBIOTICS; DNA; GENE EXPRESSION; PROTEINS;

EID: 3042715235     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2004.05.004     Document Type: Article
Times cited : (2)

References (38)
  • 1
    • 0026720075 scopus 로고
    • Tight control of gene-expression in mammalian-cells by tetracycline-responsive promoters
    • Gossen M., Bujard H. Tight control of gene-expression in mammalian-cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA. 89:1992;5547-5551
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 3
    • 0032530174 scopus 로고    scopus 로고
    • Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators
    • Pikaart M.J., Recillas-Targa F., Felsenfeld G. Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators. Genes Dev. 12:1998;2852-2862
    • (1998) Genes Dev. , vol.12 , pp. 2852-2862
    • Pikaart, M.J.1    Recillas-Targa, F.2    Felsenfeld, G.3
  • 4
    • 0023805741 scopus 로고
    • Negative effect of the transcriptional activator GAL4
    • Gill G., Ptashne M. Negative effect of the transcriptional activator GAL4. Nature. 334:1988;721-724
    • (1988) Nature , vol.334 , pp. 721-724
    • Gill, G.1    Ptashne, M.2
  • 5
    • 0032499265 scopus 로고    scopus 로고
    • Evaluation of an autoregulatory tetracycline regulated system
    • Gallia G.L., Khalili K. Evaluation of an autoregulatory tetracycline regulated system. Oncogene. 16:1998;1879-1884
    • (1998) Oncogene , vol.16 , pp. 1879-1884
    • Gallia, G.L.1    Khalili, K.2
  • 6
    • 0029866655 scopus 로고    scopus 로고
    • Tetracycline-controlled gene expression system achieves high-level and quantitative control of gene expression
    • Yin D.X., Zhu L., Schimke R.T. Tetracycline-controlled gene expression system achieves high-level and quantitative control of gene expression. Anal. Biochem. 235:1996;195-201
    • (1996) Anal. Biochem. , vol.235 , pp. 195-201
    • Yin, D.X.1    Zhu, L.2    Schimke, R.T.3
  • 7
    • 0034581163 scopus 로고    scopus 로고
    • Tet repressor-based system for regulated gene expression in eukaryotic cells: Principles and advances
    • Baron U., Bujard H. Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances. Methods Enzymol. 327:2000;401-421
    • (2000) Methods Enzymol. , vol.327 , pp. 401-421
    • Baron, U.1    Bujard, H.2
  • 8
    • 0035498826 scopus 로고    scopus 로고
    • A model system for studying postnatal myogenesis with tetracycline-responsive, genetically engineered clonal myoblasts in vitro and in vivo
    • Link D., Irintchev A., Knauf U., Wernig A., Starzinski-Powitz A. A model system for studying postnatal myogenesis with tetracycline-responsive, genetically engineered clonal myoblasts in vitro and in vivo. Exp. Cell Res. 270:2001;138-150
    • (2001) Exp. Cell Res. , vol.270 , pp. 138-150
    • Link, D.1    Irintchev, A.2    Knauf, U.3    Wernig, A.4    Starzinski-Powitz, A.5
  • 9
    • 0035783471 scopus 로고    scopus 로고
    • Evaluation of the tetracycline- and ecdysone-inducible systems for expression of neurotransmitter receptors in mammalian cells
    • Van Craenenbroeck K., Vanhoenacker P., Leysen J.E., Haegeman G. Evaluation of the tetracycline- and ecdysone-inducible systems for expression of neurotransmitter receptors in mammalian cells. Eur. J. Neurosci. 14:2001;968-976
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 968-976
    • Van Craenenbroeck, K.1    Vanhoenacker, P.2    Leysen, J.E.3    Haegeman, G.4
  • 10
    • 0034608802 scopus 로고    scopus 로고
    • Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity
    • Urlinger S., Baron U., Thellmann M., Hasan M.T., Bujard H., Hillen W. Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity. Proc. Natl. Acad. Sci. USA. 97:2000;7963-7968
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7963-7968
    • Urlinger, S.1    Baron, U.2    Thellmann, M.3    Hasan, M.T.4    Bujard, H.5    Hillen, W.6
  • 11
    • 0028795108 scopus 로고
    • Efficacy of tetracycline-controlled gene expression is influenced by cell type
    • Ackland-Berglund C.E., Leib D.A. Efficacy of tetracycline-controlled gene expression is influenced by cell type. Biotechniques. 18:1995;196-200
    • (1995) Biotechniques , vol.18 , pp. 196-200
    • Ackland-Berglund, C.E.1    Leib, D.A.2
  • 12
    • 0029081428 scopus 로고
    • Efficacy of tetracycline-controlled gene-expression is influenced by cell-type - Commentary
    • Gossen M., Bujard H. Efficacy of tetracycline-controlled gene-expression is influenced by cell-type - commentary. Biotechniques. 19:1995;213-216
    • (1995) Biotechniques , vol.19 , pp. 213-216
    • Gossen, M.1    Bujard, H.2
  • 13
    • 0029009922 scopus 로고
    • The responsiveness of a tetracycline-sensitive expression system differs in different cell lines
    • Howe J.R., Skryabin B.V., Belcher S.M., Zerillo C.A., Schmauss C. The responsiveness of a tetracycline-sensitive expression system differs in different cell lines. J. Biol. Chem. 270:1995;14168-14174
    • (1995) J. Biol. Chem. , vol.270 , pp. 14168-14174
    • Howe, J.R.1    Skryabin, B.V.2    Belcher, S.M.3    Zerillo, C.A.4    Schmauss, C.5
  • 14
    • 0035866302 scopus 로고    scopus 로고
    • A novel tetracycline-dependent transactivator with E2F4 transcriptional activation domain
    • Akagi K., Kanai M., Saya H., Kozu T., Berns A. A novel tetracycline-dependent transactivator with E2F4 transcriptional activation domain. Nucleic Acids Res. 29:2001;E23
    • (2001) Nucleic Acids Res. , vol.29 , pp. 23
    • Akagi, K.1    Kanai, M.2    Saya, H.3    Kozu, T.4    Berns, A.5
  • 15
    • 0030835644 scopus 로고    scopus 로고
    • A novel tetracycline-dependent expression vector with low basal expression and potent regulatory properties in various mammalian cell lines
    • Hoffmann A., Villalba M., Journot L., Spengler D. A novel tetracycline-dependent expression vector with low basal expression and potent regulatory properties in various mammalian cell lines. Nucleic Acids Res. 25:1997;1078-1079
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1078-1079
    • Hoffmann, A.1    Villalba, M.2    Journot, L.3    Spengler, D.4
  • 16
    • 0034098934 scopus 로고    scopus 로고
    • Ubiquitous postnatal LoxP recombination using a doxycycline auto-inducible Cre transgene (DAI-Cre)
    • Holzenberger M., Zaoui R., Leneuve P., Hamard G., Le Bouc Y. Ubiquitous postnatal LoxP recombination using a doxycycline auto-inducible Cre transgene (DAI-Cre). Genesis. 26:2000;157-159
    • (2000) Genesis , vol.26 , pp. 157-159
    • Holzenberger, M.1    Zaoui, R.2    Leneuve, P.3    Hamard, G.4    Le Bouc, Y.5
  • 17
    • 0242325359 scopus 로고    scopus 로고
    • Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line
    • Kenny P.A., Enver T., Ashworth A. Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line. BMC. Mol. Biol. 3:2002;13
    • (2002) BMC. Mol. Biol. , vol.3 , pp. 13
    • Kenny, P.A.1    Enver, T.2    Ashworth, A.3
  • 18
    • 0031962433 scopus 로고    scopus 로고
    • Efficient transgene regulation from a single tetracycline-controlled positive feedback regulatory system
    • Mohammadi S., Hawkins R.E. Efficient transgene regulation from a single tetracycline-controlled positive feedback regulatory system. Gene Ther. 5:1998;76-84
    • (1998) Gene Ther. , vol.5 , pp. 76-84
    • Mohammadi, S.1    Hawkins, R.E.2
  • 19
    • 0033580422 scopus 로고    scopus 로고
    • Efficient control of tetracycline-responsive gene expression from an autoregulated bi-directional expression vector
    • Strathdee C.A., McLeod M.R., Hall J.R. Efficient control of tetracycline-responsive gene expression from an autoregulated bi-directional expression vector. Gene. 229:1999;21-29
    • (1999) Gene , vol.229 , pp. 21-29
    • Strathdee, C.A.1    McLeod, M.R.2    Hall, J.R.3
  • 20
    • 0030797223 scopus 로고    scopus 로고
    • Tetracycline-controlled transcription in eukaryotes: Novel transactivators with graded transactivation potential
    • Baron U., Gossen M., Bujard H. Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential. Nucleic Acids Res. 25:1997;2723-2729
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2723-2729
    • Baron, U.1    Gossen, M.2    Bujard, H.3
  • 21
    • 0034682039 scopus 로고    scopus 로고
    • The p65 domain from NF-kappaB is an efficient human activator in the tetracycline-regulatable gene expression system
    • Urlinger S., Helbl V., Guthmann J., Pook E., Grimm S., Hillen W. The p65 domain from NF-kappaB is an efficient human activator in the tetracycline-regulatable gene expression system. Gene. 247:2000;103-110
    • (2000) Gene , vol.247 , pp. 103-110
    • Urlinger, S.1    Helbl, V.2    Guthmann, J.3    Pook, E.4    Grimm, S.5    Hillen, W.6
  • 22
    • 0033571986 scopus 로고    scopus 로고
    • Use of the human EF-1alpha promoter for expression can significantly increase success in establishing stable cell lines with consistent expression: A study using the tetracycline-inducible system in human cancer cells
    • Gopalkrishnan R.V., Christiansen K.A., Goldstein N.I., DePinho R.A., Fisher P.B. Use of the human EF-1alpha promoter for expression can significantly increase success in establishing stable cell lines with consistent expression: a study using the tetracycline-inducible system in human cancer cells. Nucleic Acids Res. 27:1999;4775-4782
    • (1999) Nucleic Acids Res. , vol.27 , pp. 4775-4782
    • Gopalkrishnan, R.V.1    Christiansen, K.A.2    Goldstein, N.I.3    Depinho, R.A.4    Fisher, P.B.5
  • 23
    • 0037145513 scopus 로고    scopus 로고
    • A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture
    • Anastassiadis K., Kim J., Daigle N., Sprengel R., Scholer H.R., Stewart A.F. A predictable ligand regulated expression strategy for stably integrated transgenes in mammalian cells in culture. Gene. 298:2002;159-172
    • (2002) Gene , vol.298 , pp. 159-172
    • Anastassiadis, K.1    Kim, J.2    Daigle, N.3    Sprengel, R.4    Scholer, H.R.5    Stewart, A.F.6
  • 24
    • 0031051518 scopus 로고    scopus 로고
    • Integration of tetracycline regulation into a cell-specific transcriptional enhancer
    • Rose S.D., MacDonald R.J. Integration of tetracycline regulation into a cell-specific transcriptional enhancer. J. Biol. Chem. 272:1997;4735-4739
    • (1997) J. Biol. Chem. , vol.272 , pp. 4735-4739
    • Rose, S.D.1    MacDonald, R.J.2
  • 25
    • 0029075822 scopus 로고
    • Co-regulation of two gene activities by tetracycline via a bidirectional promoter
    • Baron U., Freundlieb S., Gossen M., Bujard H. Co-regulation of two gene activities by tetracycline via a bidirectional promoter. Nucleic Acids Res. 23:1995;3605-3606
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3605-3606
    • Baron, U.1    Freundlieb, S.2    Gossen, M.3    Bujard, H.4
  • 26
    • 0033591006 scopus 로고    scopus 로고
    • Rapid selection of tetracycline-controlled inducible cell lines using a green fluorescent-transactivator fusion protein
    • Callus B.A., Mathey-Prevot B. Rapid selection of tetracycline-controlled inducible cell lines using a green fluorescent-transactivator fusion protein. Biochem. Biophys. Res. Commun. 257:1999;874-878
    • (1999) Biochem. Biophys. Res. Commun. , vol.257 , pp. 874-878
    • Callus, B.A.1    Mathey-Prevot, B.2
  • 27
    • 0031013824 scopus 로고    scopus 로고
    • Use of a dicistronic expression cassette encoding the green fluorescent protein for the screening and selection of cells expressing inducible gene products
    • Mosser D.D., Caron A.W., Bourget L., Jolicoeur P., Massie B. Use of a dicistronic expression cassette encoding the green fluorescent protein for the screening and selection of cells expressing inducible gene products. Biotechniques. 22:1997;150-161
    • (1997) Biotechniques , vol.22 , pp. 150-161
    • Mosser, D.D.1    Caron, A.W.2    Bourget, L.3    Jolicoeur, P.4    Massie, B.5
  • 28
    • 0032528299 scopus 로고    scopus 로고
    • A reliable way of obtaining stable inducible clones
    • Chambard J.C., Pognonec P. A reliable way of obtaining stable inducible clones. Nucleic Acids Res. 26:1998;3443-3444
    • (1998) Nucleic Acids Res. , vol.26 , pp. 3443-3444
    • Chambard, J.C.1    Pognonec, P.2
  • 29
    • 0029829504 scopus 로고    scopus 로고
    • Coupling efficiencies of human alpha 1-adrenergic receptor subtypes: Titration of receptor density and responsiveness with inducible and repressible expression vectors
    • Theroux T.L., Esbenshade T.A., Peavy R.D., Minneman K.P. Coupling efficiencies of human alpha 1-adrenergic receptor subtypes: titration of receptor density and responsiveness with inducible and repressible expression vectors. Mol. Pharmacol. 50:1996;1376-1387
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1376-1387
    • Theroux, T.L.1    Esbenshade, T.A.2    Peavy, R.D.3    Minneman, K.P.4
  • 30
    • 0034509652 scopus 로고    scopus 로고
    • A novel doxycycline inducible autoregulatory plasmid which displays "on"/"off" regulation suited to gene therapy applications
    • Gould D.J., Berenstein M., Dreja H., Ledda F., Podhajcer O.L., Chernajovsky Y. A novel doxycycline inducible autoregulatory plasmid which displays "on"/"off" regulation suited to gene therapy applications. Gene Ther. 7:2000;2061-2070
    • (2000) Gene Ther. , vol.7 , pp. 2061-2070
    • Gould, D.J.1    Berenstein, M.2    Dreja, H.3    Ledda, F.4    Podhajcer, O.L.5    Chernajovsky, Y.6
  • 31
    • 0034714149 scopus 로고    scopus 로고
    • Variability of transcriptional regulation after gene transfer with the retroviral tetracycline system
    • Paulus W., Baur I., Keyvani K., Senner V. Variability of transcriptional regulation after gene transfer with the retroviral tetracycline system. J. Biotechnol. 81:2000;159-165
    • (2000) J. Biotechnol. , vol.81 , pp. 159-165
    • Paulus, W.1    Baur, I.2    Keyvani, K.3    Senner, V.4
  • 33
    • 0034108454 scopus 로고    scopus 로고
    • A versatile chondrogenic rat calvaria cell line R-tTA-24 that permits tetracycline-regulated gene expression
    • Bergwitz C., Wendlandt T., Potter E., Glomb I., Gras K., von zur M.A., Brabant G. A versatile chondrogenic rat calvaria cell line R-tTA-24 that permits tetracycline-regulated gene expression. Histochem. Cell Biol. 113:2000;145-150
    • (2000) Histochem. Cell Biol. , vol.113 , pp. 145-150
    • Bergwitz, C.1    Wendlandt, T.2    Potter, E.3    Glomb, I.4    Gras, K.5    Von Zur, M.A.6    Brabant, G.7
  • 34
    • 0038070048 scopus 로고    scopus 로고
    • P-glycoprotein, expressed in multidrug resistant cells, is not responsible for alterations in membrane fluidity or membrane potential
    • Aleman C., Annereau J.P., Liang X.J., Cardarelli C.O., Taylor B., Yin J.J., Aszalos A., Gottesman M.M. P-glycoprotein, expressed in multidrug resistant cells, is not responsible for alterations in membrane fluidity or membrane potential. Cancer Res. 63:2003;3084-3091
    • (2003) Cancer Res. , vol.63 , pp. 3084-3091
    • Aleman, C.1    Annereau, J.P.2    Liang, X.J.3    Cardarelli, C.O.4    Taylor, B.5    Yin, J.J.6    Aszalos, A.7    Gottesman, M.M.8
  • 35
    • 0029021083 scopus 로고
    • A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice
    • Shockett P., Difilippantonio M., Hellman N., Schatz D.G. A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice. Proc. Natl. Acad. Sci. USA. 92:1995;6522-6526
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 6522-6526
    • Shockett, P.1    Difilippantonio, M.2    Hellman, N.3    Schatz, D.G.4
  • 36
    • 0030867445 scopus 로고    scopus 로고
    • Delay in resumption of the activity of tetracycline-regulatable promoter following removal of tetracycline analogues
    • Mohammadi S., Alvarez-Vallina L., Ashworth L.J., Hawkins R.E. Delay in resumption of the activity of tetracycline-regulatable promoter following removal of tetracycline analogues. Gene Ther. 4:1997;993-997
    • (1997) Gene Ther. , vol.4 , pp. 993-997
    • Mohammadi, S.1    Alvarez-Vallina, L.2    Ashworth, L.J.3    Hawkins, R.E.4
  • 37
    • 0028244325 scopus 로고
    • Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance
    • Hinrichs W., Kisker C., Duvel M., Muller A., Tovar K., Hillen W., Saenger W. Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance. Science. 264:1994;418-420
    • (1994) Science , vol.264 , pp. 418-420
    • Hinrichs, W.1    Kisker, C.2    Duvel, M.3    Muller, A.4    Tovar, K.5    Hillen, W.6    Saenger, W.7
  • 38
    • 0026086395 scopus 로고
    • Structural requirements of tetracycline-Tet repressor interaction: Determination of equilibrium binding constants for tetracycline analogs with the Tet repressor
    • Degenkolb J., Takahashi M., Ellestad G.A., Hillen W. Structural requirements of tetracycline-Tet repressor interaction: determination of equilibrium binding constants for tetracycline analogs with the Tet repressor. Antimicrob. Agents Chemother. 35:1991;1591-1595
    • (1991) Antimicrob. Agents Chemother. , vol.35 , pp. 1591-1595
    • Degenkolb, J.1    Takahashi, M.2    Ellestad, G.A.3    Hillen, W.4


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