Ethyl-eicosapentaenoic acid ingestion prevents corticosterone-mediated memory impairment induced by central administration of interleukin-1β in rats

Molecular Psychiatry

Volumn 9, Issue 6, 2004, Pages 630-638

  Song, C ^a   Phillips, A G ^a   Leonard, B E ^b   Horrobin, D F ^c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Laxdale Ltd   (United Kingdom)

Author keywords

Corticosterone; Ethyl EPA; Interleukin 1 ; PGE2 and IL 10; Radial maze; RU486; Spatial working memory

Indexed keywords

ARACHIDONIC ACID; CORTICOSTERONE; ICOSAPENTAENOIC ACID ETHYL ESTER; INTERLEUKIN 10; INTERLEUKIN 1BETA; MITOGENIC AGENT; OMEGA 3 FATTY ACID; PROSTAGLANDIN E2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTIFICIAL DIET; COGNITION; CONTROLLED STUDY; MALE; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; RAT; WORKING MEMORY;

ADMINISTRATION, ORAL; ANIMALS; CORTICOSTERONE; DINOPROSTONE; EICOSAPENTAENOIC ACID; INTERLEUKIN-1; INTERLEUKIN-10; MALE; MEMORY; MEMORY DISORDERS; RATS; RATS, LONG-EVANS; SPACE PERCEPTION;

EID: 3042701265     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4001462     Document Type: Article

References (55)

1. Maier S, Watkins L. Cytokines for psychologists: implications of bidirectional immune-to-brain communication for understanding behavior, mood, and cognition. Psychol Rev 1998; 105: 83-107.
2. Pugh CR, Nguyen KT, Gonyea J, Fleshner M, Wakins LR, Maier SF et al. Role of interleukin-1 beta in impairment of contextual fear conditioning caused by social isolation. Behav Brain Res 1999; 106: 109-118.
3. Schackert G, Simmons RD, Buzbee TM, Hume DA, Fidler IJ. Macrophage infiltration into experimental brain metastases: occurrence through an intact blood-brain barrier. J Natl Cancer Inst 1988; 80: 1027-1034.
4. Sedgwick JD. T-lymphocyte activation and regulation in the central nervous system. Biochem Soc Trans 1997; 25: 673-679.
5. Kastin A, Pan W, Maness LM, Banks WA. Peptides cross the blood-brain barrier: some unusual observation. Brain Res 1999; 848: 96-100.
6. Rivest S, Lacroix S, Vallieres L, Nadeau S, Zhang J, Laflamme N. How the blood talks to the brain parenchyma and the paraventricular nucleus of the hypothalamus during systemic inflammatory and infectious stimuli. Proc Soc Exp Bio Med 2000; 223: 22-38.
7. Engblom D, Ek M, Saha S, Ericsson-Dahlstrand A, Jakobsson PJ, Blomqvist A. Prostaglandins as inflammatory messengers across the blood-brain barrier. J Mol Med 2002; 80: 5-15.
8. Dunn AJ. Cytokine activation of the HPA axis. Ann NY Acad Sci 2000; 917: 608-617.
9. Schmidt ED, Janszen AW, Wouterlood FG, Tilders FJ. Interleukin-1-induced long-lasting changes in hypothalamic corticotropin-releasing hormone (CRH) neurons and hyperresponsiveness of the hypothalamus-pituitary-adrenal axis. J Neurosci 1995; 15: 7417-7426.
10. Parsadaniantz SM, Lebeau A, Duval P, Grimaldi B, Terlain B, Kerdelhue B. Effects of the inhibition of cyclo-oxygenase 1 or 2 or 5-lipoxygenase on the activation of the hypothalamic-pituitary-adrenal axis induced by interleukin-1beta in the male rat. J Neuroendocrinol 2000; 12: 766-773.
11. Schneider H, Pitossi F, Balschun D, Wagner A, del Rey A, Besedovsky HO. A neuromodulatory role of interleukin-1beta in the hippocampus. Proc Natl Acad Sci USA 1998; 95: 7778-7783.
12. Squire LR. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol Rev 1992; 99: 195-231.
13. Eichenbaum H, Stewart C, Morris RG. Hippocampal representation in place learning. J Neurosci 1990; 10: 3531-3542.
14. Xu L, Anwyl R, Rowan MJ. Glucocorticoid receptor and protein/ RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress. Proc Natl Acad Sci USA 1998; 95: 3204-3208.
15. McEwen BS. Possible mechanisms for atrophy of the human hippocampus. Mol Psychiatry 1997; 2: 255-262.
16. Conrad CD, Lupien SJ, McEwen BS. Neurobiol Learn Mem 1999; 72: 39-46.
17. Rey M, Carlier E, Talmi M, Soumireu-Mourat B. Corticosterone effects on long-term potentiation in mouse hippocampal slices. Neuroendocrinology 1994; 60: 36-41.
18. Floresco SB, Seamans JK, Phillips AG. Selective roles for hippocampal, prefrontal cortical, and ventral striatal circuits in radial-arm maze tasks with or without a delay. J Neurosci 1997; 17: 1880-1890.
19. James M, Gibson R, Cleland L. Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr 2000; 71: 343S-348S.
20. Song C, Li XW, Leonard BE, Horrobin DF. Effects of dietary n-3 or n-6 fatty acids on interleukin-1beta-induced anxiety, stress and inflammatory responses in rats. J Lipid Res 2003; 44: 1984-1991.
21. Song C, Barley B, Leonard BE. Behavioral, neurochemical, and immunological responses to CRF administration, Is CRF a mediator of stress? Ann N Y Acad Sci 1995; 771: 55-72.
22. Calvo N, Volosin M. Glucocorticoid and mineralocorticoid receptors are involved in the facilitation of anxiety-like response induced by restraint. Neuroendocrinology 2001; 73: 261-271.
23. Floresco SB, Braaksma DN, Phillips AG. Thalamic-cortical-striatal circuitry subserves working memory during delayed responding on a radial arm maze. J Neurosci 1999; 19: 11061-11071.
24. Seamans JK, Floresco SB, Phillips AG. D1 receptor modulation of hippocampal-prefrontal cortical circuits integrating spatial memory with executive functions in the rat. J Neurosci 1998; 18: 1613-1621.
25. Maes M, Song C, Lin AH, Bonaccorso S, Kenis G, De Jongh R et al. Negative immunoregulatory effects of antidepressants; inhibition of interferon-gamma and stimulation of interleukin-10 secretion. Neuropsychopharmacology 1999; 20: 370-379.
26. Weinberg J, Bezio S. Alcohol-induced changes in pituitary-adrenal activity during pregnancy. Alcohol Clin Exp Res 1987; 11: 274-280.
27. Oitzl MS, Fluttert M, Sutanto W, de Kloet ER. Continuous blockade of brain glucocorticoid receptors facilitates spatial learning and memory in rats. Eur J Neurosci 1998; 10: 3759-3766.
28. Oitzl MS, Fluttert M, de Kloet ER. Acute blockade of hippocampal glucocorticoid receptors facilitates spatial learning in rats. Brain Res 1998; 797: 159-162.
29. Oitzle MS, de Kloet ER. Selective corticosteroid antagonists modulate specific aspects of spacial orientation learning. Behav Neurosci 1992; 106: 62-71.
30. Douma BR, Korte SM, Buwalda B, la Fleur SE, Bohus B, Luiten PG. Repeated blockade of mineralocorticoid receptors, but not of glucocorticoid receptors impairs food rewarded spatial learning. Psychoneuroendocrinology 1998; 23: 33-44.
31. Heikinheimo O, Kekkonen R. Dose-response relationships of RU 486. Ann Med 1993; 25: 71-76.
32. Ikemoto A, Ohishi M, Sato Y, Hata N, Misawa Y, Fujii Y et al. Reversibility of n-3 fatty acid deficiency-induced alterations of learning behavior in the rat: level of n-6 fatty acids as another critical factor. J Lipid Res 2001; 42: 1655-1663.
33. Carrie I, Clement M, de Javel D, Frances H, Bourre JM. Phospholipid supplementation reverses behavioral, biochemical alterations induced by n-3 polyunsaturated fatty acid deficiency in mice. J Lipid Res 2000; 41: 473-480.
34. Umezawa M, Kogishi K, Tojo H, Yoshimura S, Seriu N, Ohta A et al. High-linoleate, high-alpha-linolenate diets affect learning ability, natural behavior in SAMR1 mice. J Nutr 1999; 129: 431-437.
35. Kato J, Takano A, Mitsuhashi N, Koike N, Yoshida K, Hirata S. Modulation of brain progestin, glucocorticoid receptors by unsaturated fatty acid, phospholipid. J Steroid Biochem 1987; 27: 641-648.
36. Valletta G, Sumida C, Thobie N, Nunez EA. Unsaturated fatty acids synergistically enhance glucocorticoid-induced gene expression. Cell Signal 1995; 7: 319-323.
37. Gottlicher M, Widmark E, Li Q, Gustafsson JA. Fatty acids activate a chimera of the clofibric acid-activated receptor, the glucocorticoid receptor. Proc Natl Acad Sci USA 1992; 89: 4653-4657.
38. Sumida C, Vallette G, Nunez EA. Interaction of unsaturated fatty acids with rat liver glucocorticoid receptors: studies to localize the site of interaction. Acta Endocrinol (Copenh) 1993; 129: 348-355.
39. Song C. The effect of thymectomy and IL-1 on memory: implications for the relationship between immunity and depression. Brain Behav Immunol 2002; 16: 557-568.
40. Zhang J, Revist S. A functional analysis of EP4 receptor-expressing neurons in mediating the action of prostaglandin E2 within specific nuclei of the brain in response to circulating interleukin-1beta. J Neurochem 2000; 74: 2134-2145.
41. De Pablo MA, De Cienfuegos GA. Modulatory effects of dietary lipids on immune system functions. Immunol Cell Biol 2000; 78: 31-39.
42. Dartois E, Bouton MM. Inhibition by glucocorticoids of PGE2, ACTH secretion induced by phorbol esters, EGF in rat pituitary cells. J Steroid Biochem 1988; 30: 333-336.
43. Ericsson A, Arias C, Sawchenko PE. Evidence for an intramedullary prostaglandin-dependent mechanism in the activation of stress-related neuroendocrine circuitry by intravenous interleukin-1. J Neurosci 1997; 17: 7166-7179.
44. Kozak W, Soszynski D, Rudolph K, Conn CA, Kluger MJ. Dietary n-3 fatty acids differentially affect sickness behavior in mice during local, systemic inflammation. Am J Physiol 1997; 272(Part 2): R1298-1307.
45. Romagnani S. Biology of human TH1 and TH2 cells. J Clin Immunol 1995; 15: 121-129.
46. Lucey DR, Clerici M, Shearer GM. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin Microbiol Rev 1996; 9: 532-562.
47. Song C, Halbreich U, Han C, Leonard BE, Meng FQ, Lou HC et al. Effects of electronic acupuncture and fluoxetine treatments on plasma concentrations of pro- and anti-inflammatory cytokines in normal controls and depressed patients. Official Publication of the American College of Neuropsychopharmacology, Abstract, p 93.
48. De Luigi A, Fragiacomo C, Lucca U, Quadri P, Tettamanti M, Grazia De Simoni M. Inflammatory markers in Alzheimer's disease and multi-infarct dementia. Mech Ageing Dev 2001; 122: 1985-1995.
49. Lukiw WJ, Bazan NG. Neuroinflammatory signaling upregulation in Alzheimer's disease. Neurochem Res 2000; 25: 1173-1184.
50. Maes M, Smith R, Christophe A, Cosynes P, Desnyder R, Meltzer H. Fatty acid composition in major depression: decreased omega 3 fractions in cholesteryl esters, increased C20:4omega 6/C20:5 omega 3 ratio in cholesteryl esters, phospholipids. J Affect Dis 1996; 38: 35-46.
51. Conquer JA, Tierney MC, Zecevic J, Bettger WJ, Fisher RH. Fatty acid analysis of blood plasma of patients with Alzheimer's disease, other types of dementia, and cognitive impairment. Lipids 2000; 35: 1305-1312.
52. Nemets B, Stahl Z, Belmaker RH. Addition of omega-3 fatty acid to maintenance medication treatment for recurrent unipolar depressive disorder. Am J Psychiatry 2002; 159: 477-479.
53. Peet M, Horrobin DF. A dose-ranging study of the effects of ethyleicosapentaenoate in patients with ongoing depression despite apparently adequate treatment with standard drugs. Arch Gen Psychiatry 2002; 59: 913-919.
54. Yehuda S, Carasso R. Modulation of learning, pain thresholds, and thermoregulation in the rat by preparation of free purified a-linolenic and linoleic acids: determination of the optimal ω-3-to ω-6 ratio. Proc Natl Acad Sci USA 1993; 90: 10345-10349.
55. Umezawa M, Kogishi K, Tojo H, Yoshimura S, Seriu N, Ohta A et al. High-linoleate and high-alpha-linolenate diets affect learning ability and natural behavior in SAMR1 mice. J Nutr 1999; 129: 431-437.