A biophysical characterisation of factors controlling dimerisation and selectivity in the NF-κB and NFAT families

Journal of Molecular Biology

Volumn 339, Issue 5, 2004, Pages 1059-1075

  De Lumley, Marie ^a   Hart, Darren J ^a   Cooper, Matthew A ^a   Symeonides, Stefan ^a   Blackburn, Jonathan M ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF THE WESTERN CAPE   (South Africa)

Author keywords

AUC, analytical ultracentrifugation; dimerisation; EMSA, electrophoretic mobility shift assay; evolution; MBP, maltose binding protein; NFAT family; Rel family; RHR, Rel homology region; RU, response unit; SPR, surface plasmon resonance; transcription factors

Indexed keywords

CHIMERIC PROTEIN; DIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN P 50; MONOMER; PROTEIN P50; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; DNA; DNA BINDING PROTEIN; HYBRID PROTEIN; NFATC1 PROTEIN, MOUSE; NUCLEAR PROTEIN; PROTEIN SUBUNIT;

ARTICLE; BINDING AFFINITY; CHIMERA; CONTROLLED STUDY; DATA ANALYSIS; DIMERIZATION; DNA BINDING; DNA SPLICING; HUMAN; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; REPORTER GENE; SEQUENCE ALIGNMENT;

EUKARYOTA; HOMO;

AMINO ACID SEQUENCE; ANIMALS; DIMERIZATION; DNA; DNA-BINDING PROTEINS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; TRANSCRIPTION FACTORS;

EID: 3042677688     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.03.083     Document Type: Article

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