Critical in vivo roles for classical estrogen receptors in rapid estrogen actions on intracellular signaling in mouse brain

Endocrinology

Volumn 145, Issue 7, 2004, Pages 3055-3061

  Ábrahám, István M ^a,b   Todman, Martin G ^a   Korach, Kenneth S ^c   Herbison, Allan E ^a,d  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; ESTROGEN ACTIVITY; FEMALE; IMMUNOCOMPETENT CELL; IMMUNOREACTIVITY; IN VIVO STUDY; MEDIAL PREOPTIC AREA; MEDICAL ASSESSMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGENS; FEMALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; PHOSPHORYLATION; RECEPTORS, ESTROGEN;

EID: 3042645224     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-1676     Document Type: Article

References (42)

1. McEwen BS, Alves SE 1999 Estrogen actions in the central nervous system. Endocr Rev 20:279-307
2. Pfaff DW, Schwartz-Giblin S, McCarthy MM, Kow L-M 1994 Cellular and molecular mechanisms of female reproductive behaviors. In: Knobil E, Neill JD, eds. The physiology of reproduction. New York: Raven Press Ltd.; 107-220
3. Kelly MJ, Levin ER 2001 Rapid actions of plasma membrane estrogen receptors. Trends Endocrinol Metab 12:152-156
4. Migliaccio A, Castoria G, Di Domenico M, de Falco A, Bilancio A, Lombardi M, Barone MV, Ametrano D, Zannini MS, Abbondanza C, Auricchio F 2000 Steroid-induced androgen receptor-oestradiol receptor β-Src complex triggers prostate cancer cell proliferation. EMBO J 19:5406-5417
5. Singer CA, Figueroa-Masot XA, Batchelor RH, Dorsa DM 1999 The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. J Neurosci 19:2455-2463
6. Song RX-D, McPherson RA, Adam L, Bao Y, Shupnik M, Kumar R, Santen RJ 2002 Linkage of rapid estrogen action to MAPK activation by ERα-Shc association and Shc pathway activation. Mol Endocrinol 16:116-127
7. Dos Santos EG, Dieudonne MN, Pecquery R, Le Moal V, Giudicelli Y, Lacasa D 2002 Rapid nongenomic E2 effects on p42/p44 MAPK, activator protein-1, and cAMP response element binding protein in rat white adipocytes. Endocrinology 143:930-940
8. Razandi M, Pedram A, Greene GL, Levin ER 1999 Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERα and ERβ expressed in Chinese hamster ovary cells. Mol Endocrinol 13:307-319
9. Kousteni S, Bellido T, Plotkin LI, O'Brien CA, Bodenner DL, Han L, Han K, DiGregorio GB, Katzenellenbogen JA, Katzenellenbogen BS, Robertson PK, Weinstein RS, Jilka RL, Manolagas SC 2001 Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity. Cell 104:719-730
10. Nadal A, Ropero AB, Laribi O, Maillet M, Fuentes E, Soria B 2000 Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor α and estrogen receptor β. Proc Natl Acad Sci USA 97:11603-11608
11. Benten WPM, Stephan C, Lieberherr M, Wunderlich F 2001 Estradiol signalling via sequestrable surface receptors. Endocrinology 142:1669-1677
12. Kelly MJ, Wagner EJ 2000 Estrogen modulation of G-protein-coupled receptors. Trends Endocrinol Metab 10:369-374
13. Gu Q, Korach KS, Moss RL 1999 Rapid action of 17β-estradiol on kainate-induced currents in hippocampal neurons lacking intracellular estrogen receptors. Endocrinology 140:660-666
14. Boyan BD, Sylvia VL, Frambach T, Lohmann CH, Dietl J, Dean DD, Schwartz Z 2003 Estrogen-dependent rapid activation of protein kinase C in estrogen receptor-positive MCF-7 breast cancer cells and estrogen receptor-negative HCC38 cells is membrane-mediated and inhibited by tamoxifen. Endocrinology 144:1812-1824
15. Qiu J, Bosch MA, Tobias SC, Grandy DK, Scanlan TS, Ronnekleiv OK, Kelly MJ 2003 Rapid signaling of estrogen in hypothalamic neurons involves a novel G protein-coupled estrogen receptor that activates protein kinase C. J Neurosci 23:9529-9540
16. Toran-Allerand CD, Guan X, MacLusky NJ, Horvath TL, Diano S, Singh M, Connolly Jr ES, Nethrapalli IS, Tinnikov AA 2002 ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury. J Neurosci 22:8391-8401
17. Valverde MA, Rojas P, Amigo J, Cosmelli D, Orio P, Bahamonde MI, Mann GE, Vergara C, Latorre R 1999 Acute activation of Maxi-K channels (hSlo) by estradiol binding to the β subunit. Science 285:1929-1931
18. Wetzel CH, Hermann B, Behl C, Pestel E, Rammes G, Zieglgansberger W, Holsboer F, Rupprecht R 1998 Functional antagonism of gonadal steroids at the 5-hydroxytryptamine type 3 receptor. Mol Endocrinol 12:1441-1451
19. Paradiso K, Zhang J, Steinbach JH 2001 The C terminus of the human nicotinic α4β2 receptor forms a binding site required for potentiation by an estrogenic steroid. J Neurosci 21:6561-6568
20. Shaywitz AJ, Greenberg ME 1999 CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 68:821-861
21. Gu G, Rojo AA, Zee MC, Yu J, Simerly RB 1996 Hormonal regulation of CREB phosphorylation in the anteroventral periventricular nucleus. J Neurosci 16:3035-3044
22. Zhou Y, Watters JJ, Dorsa DM 1996 Estrogen rapidly induces the phosphorylation of the cAMP response element binding protein in rat brain. Endocrinology 137:2163-2166
23. Carlstrom L, Ke ZJ, Unnerstall JR, Cohen RS, Pandey SC 2001 Estrogen modulation of the cyclic AMP response element-binding protein pathway. Effects of long-term and acute treatments. Neuroendocrinology 74:227-243
24. Krege JH, Hodgin JB, Couse JF, Enmark E, Warner M, Magler JF, Sar M, Korach KS, Gustafsson J-A, Smithies O 1998 Generation and reproductive phenotypes of mice lacking estrogen receptor β. Proc Natl Acad Sci USA 95:15677-15682
25. Lubahn DB, Moyer JS, Golding TS, Couse JF, Korach KS, Smithies O 1993 Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc Natl Acad Sci USA 90:11162-11166
26. Couse JF, Yates MM, Walker VR, Korach KS 2003 Characterization of the hypothalamic-pituitary-gonadal axis in estrogen receptor (ER) null mice reveals hypergonadism and endocrine sex reversal in females lacking ERα but not ERβ. Mol Endocrinol 17:1039-1053
27. Abraham IM, Han K, Todman MG, Korach KS, Herbison AE 2003 Estrogen receptor β mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo. J Neurosci 23:5771-5777
28. McNulty S, Schurov IL, Sloper PJ, Hastings MH 1998 Stimuli which entrain the circadian clock of the neonatal Syrian hamster in vivo regulate the phosphorylation of the transcription factor CREB in the suprachiasmatic nucleus in vitro. Eur J Neurosci 10:1063-1072
29. von Gall C, Duffield GE, Hastings MH, Kopp MD, Dehghani F, Korf HW, Stehle JH 1998 CREB in the mouse SCN: a molecular interface coding the phase-adjusting stimuli light, glutamate, PACAP, and melatonin for clockwork access. J Neurosci 18:10389-10397
30. Singh M, Setalo Jr GJ, Guan X, Frail DE, Toran-Allerand CD 2000 Estrogen-induced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-α knock-out mice. J Neurosci 20:1694-1700
31. Mitra SW, Hoskin E, Yudkovitz J, Pear L, Wilkinson HA, Hayashi S, Pfaff DW, Ogawa S, Rohrer SP, Schaeffer JM, McEwen BS, Alves SE 2003 Immunolocalization of estrogen receptor β in the mouse brain: comparison with estrogen receptor α. Endocrinology 144:2055-2067
32. Shughrue P, Scrimo P, Lane M, Askew R, Merchenthaler I 1997 The distribution of estrogen receptor-β mRNA in forebrain regions of the estrogen receptor-α knockout mouse. Endocrinology 138:5649-5652
33. Franklin KBJ, Paxinos G 1997 The mouse brain in stereotaxic coordinates. San Diego: Academic Press
34. Dubal DB, Zhu H, Yu J, Rau SW, Shughrue PJ, Merchenthaler I, Kindy MS, Wise PM 2001 Estrogen receptor α, not β, is a critical link in estradiol-mediated protection against brain injury. Proc Natl Acad Sci USA 98:1952-1957
35. Herbison AE, Pape JR 2001 New evidence for estrogen receptors in gonadotropin-releasing hormone neurons. Front Neuroendocrinol 22:292-308
36. Shughrue PJ, Scrimo PJ, Merchenthaler I 1998 Evidence for the colocalization of estrogen receptor-β mRNA and estrogen receptor-α immunoreactivity in neurons of the rat forebrain. Endocrinology 139:5267-5270
37. Greco B, Allegretto EA, Tetel MJ, Blaustein JD 2001 Coexpression of ER β with ER α and progestin receptor proteins in the female rat forebrain: effects of estradiol treatment. Endocrinology 142:5172-5181
38. Shughrue PJ, Askew GR, Dellovade TL, Merchenthaler I 2002 Estrogen-binding sites and their functional capacity in estrogen receptor double knockout mouse brain. Endocrinology 143:1643-1650
39. Hisamoto K, Ohmichi M, Kurachi H, Hayakawa J, Kanda Y, Nishio Y, Adachi K, Tasaka K, Miyoshi E, Fujiwara N, Taniguchi N, Murata Y 2001 Estrogen induces the Akt-dependent activation of endothelial nitric-oxide synthase in vascular endothelial cells. J Biol Chem 276:3459-3467
40. Wade CB, Robinson S, Shapiro RA, Dorsa DM 2001 Estrogen receptor (ER)α and ERβ exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway. Endocrinology 142:2336-2342
41. Cowley SM, Hoare S, Mosselman S, Parker MG 1997 Estrogen receptors α and β form heterodimers on DNA. J Biol Chem 272:19858-19862
42. Vasudevan N, Kow LM, Pfaff DW 2001 Early membrane estrogenic effects required for full expression of slower genomic actions in a nerve cell line. Proc Natl Acad Sci USA 98:12267-12271