Stimuli which entrain the circadian clock of the neonatal Syrian hamster in vivo regulate the phosphorylation of the transcription factor CREB in the suprachiasmatic nucleus in vitro

European Journal of Neuroscience

Volumn 10, Issue 3, 1998, Pages 1063-1072

  McNulty, S ^a,b   Schurov, I L ^a   Sloper, P J ^a   Hastings, M H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

Circadian rhythms; CREB; Dopamine; Glutamate; Melatonin; Signal transduction; Suprachiasmatic nuclei

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CALCIUM BINDING PROTEIN; DOPAMINE; FORSKOLIN; GLUTAMIC ACID; KAINIC ACID; MELATONIN; MICROTUBULE ASSOCIATED PROTEIN 2; N METHYL DEXTRO ASPARTIC ACID; SYNTHETIC PEPTIDE; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; CELL CULTURE; CELL TYPE; CIRCADIAN RHYTHM; COCULTURE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; HYPOTHALAMUS; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SUPRACHIASMATIC NUCLEUS; SYRIAN HAMSTER;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CELLS, CULTURED; CIRCADIAN RHYTHM; CRICETINAE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOPAMINE; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; MELATONIN; MESOCRICETUS; PHENOTYPE; PHOSPHORYLATION; RATS; SUPRACHIASMATIC NUCLEUS;

EID: 0031903524     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1998.00114.x     Document Type: Article

References (47)

1. Armstrong, S.M. (1989) Melatonin and circadian control in mammals. Experientia, 45, 932-938.
2. Bading, H., Ginty, D.D. & Greenberg, M.E. (1993) Regulation of gene expression in hippocampal neurons by distinct calcium signalling pathways. Science, 260, 181-186.
3. Bading, H., Segal, M.M., Suchner, N.J., Dudek, H., Lipton, S.A. & Greenberg, M.E. (1995) N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons. Neurosci., 64, 653-664.
4. Crosthwaite, S.K., Dunlap, J.C. & Loros, J.J. (1997) Neurospora wc-1 and wc-2 transcription, photoresponses, and the origins of circadian rhythmicity. Science, 276, 763-769.
5. Davis, F.C. & Mannion, J. (1988) Entrainment of hamster pup circadian rhythms by prenatal melatonin injections. Am. J. Physiol., 255, R439-R448.
6. Ding, J.M., Chen, D., Weber, E.T., Fairman, L.E., Rea, M.A. & Gillette, M.U. (1994) Resetting the biological clock: mediation of nocturnal circadian shifts by glutamate and NO. Science, 266, 1713-1717.
7. Ding, J.M., Faiman, L.E., Hurst, W.J., Kuriashkina, L.R. & Gillette, M.U. (1997) Resetting the biological clock: mediation of nocturnal CREB phosphorylation via light, glutamate and nitric oxide. J. Neurosci., 17, 667-675.
8. Ebling, F.J.R (1996) The role of glutamate in the photic regulation of the suprachiasmatic nucleus. Prog. Neurobiol., 50, 109-132.
9. Ebling, F.J.P., Maywood, E.S., Staley, K., Humby, T., Hancock, D.C., Waters, C.M., Evan, G.I. & Hastings, M.H. (1991) The role of NMDA-type glutamatergic neurotransmission in the photic induction of immediate-early gene expression in the suprachiasmatic nuclei of the Syrian hamster. J. Neuroendocrinol., 3, 641-652.
10. Ghosh, A. & Greenberg, M.E. (1995) Calcium signalling in neurons: molecular mechanisms and cellular consequences. Science, 268, 239-247.
11. Ginty, D.D., Bonni, A. & Greenberg, M.E. (1994) Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell, 77, 713-725.
12. Ginty, D.D., Kornhauser, J.M., Thompson, M.A., Bading, H., Mayo, K.E., Takahashi, J.S. & Greenberg, M.E. (1993) Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science, 260, 238-241.
13. 1a melatonin receptor is coupled to parallel signal transduction pathways. Endocrinol., 138, 397-404.
14. 133. Cell, 59, 675-680.
15. Grosse, J., Velickovic, A. & Davis, F.C. (1996) Entrainment of Syrian hamster circadian activity rhythms by neonatal melatonin injections. Am. J. Physiol., 270, R533-R540.
16. Hardingham, G.E., Chawla, S., Johnson, C.M. & Bading, H. (1997) Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature, 385, 260-265.
17. Hastings, M.H. (1995) Circadian rhythms: peering into the molecular clockwork. J. Neuroendocrinol., 7, 331-340.
18. Hastings, M.H., Best, J.D., Ebling, F.J.P., Maywood, E.S., McNulty, S., Schurov, I., Selvage, D., Sloper, P. & Smith, K.L. (1996) Entrainment of the circadian clock. Prog. Brain Res., 111, 147-174.
19. Hastings, M.H., Ebling, F.J.P., Grosse, J., Herbert, J., Maywood, E.S., Mikkelsen, J.D. & Sumova, A. (1995) Immediate-early genes and the neural bases of photic and non-photic entrainment. Ciba Found. Symp., 183, 175-197.
20. Hastings, M.H., Mead, S.M., Vmdlacheruvu, R.R., Ebling, F.J.P., Maywood, E.S. & Grosse, J. (1992) Non-photic phase shifting of the circadian activity rhythm of Syrian hamster: the relative potency of arousal and melatonin. Brain Res., 591, 20-26.
21. Hazlerigg, D.G., Morgan, P.J., Lawson, W. & Hastings, M.H. (1991) Melatonin inhibits the activation of cyclic AMP-dependent protein kinase in cultured pars tuberalis cells from ovine pituitary. J. Neuroendocrinol., 3, 597-603.
22. Iuvone, P.M. & Gan, J. (1995) Functional interaction of melatonin receptors and DI dopamine receptors in cultured chick retinal neurons. J. Neurosci., 15, 2179-2185.
23. Kebabian, J.W., Agui, T., van Oene, J.C., Shigematsa, K. & Saavedra, J.M. (1986) Trends. Pharmacol. Sci., 7, 96-99.
24. Kopp, M., Meissl, H. & Korf, H.-W. (1997) The pituitary adenylate cyclase-activating polypeptide-induced phosphorylation of the transcription factor CREB (cAMP response element binding protein) in the rat suprachiasmatic nucleus is inhibited by melatonin. Neurosci. Lett., 227, 145-148.
25. Kornhauser, J.M., Ginty, D.D., Greenberg, M.E., Mayo, K.E. & Takahashi, J.S. (1996) Light entrainment and activation of signal transduction pathways in the SCN. Prog. Brain Res., 111, 133-146.
26. Liu, F.-C. & Graybiel, A.M. (1996) Spatiotemporal dynamics of CREB phosphorylation; transient vs. sustained phosphorylation in the developing striatum. Neuron, 17, 1133-1144.
27. Liu, C., Weaver, D.R., Jin, X., Shearman, L.P., Pieschi, R.L., Gribkoff, V.K. & Reppert, S.M. (1997) Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock. Neuron, 19, 91-102.
28. Margraf, R.R. & Lynch, G.R. (1993) Melatonin injections affect circadian behaviour and SCN neurophysiology in Djungarian hamsters. Am. J. Physiol., 33, R615-R621.
29. Maywood, E.S., Bittman, E.L., Ebling, F.J.P., Barren, P., Morgan, P.J. & Hastings, M.H. (1995) Regional distribution of iodomelatonin binding sites within the suprachiasmatic nucleus of the Syrian hamster and the Siberian hamster. J. Neuroendocrinol., 7, 215-224.
30. McNulty, S., McNulty, T.J., Schurov, I.L., Morgan, P.J. & Hastings, M.H. (1997) Melatonin-sensitive, serum-stimulated signalling in ovine pars tuberalis. J. Pineal. Res., 22, 221-231.
31. McNulty, S., Ross, A.W., Barrett, P., Hastings, M.H. & Morgan, P.J. (1994) Melatonin regulates the phosphorylation of CREB in ovine pars tuberalis. J. Neuroendocrinol., 6, 523-532.
32. McNulty, S., Ross, A.W., Shiu, K.Y., Morgan, P.J. & Hastings, M.H. (1996) Phosphorylation of CREB in ovine pars tuberalis is regulated both by cyclic AMP-dependent and cyclic AMP-independent mechanisms. J. Neuroendocrinol., 8, 635-645.
33. Moore, R.Y. & Speh, J.C. (1993) GABA is the principal neurotransmitter of the circadian system. Neurosci. Lett., 150, 112-116.
34. Morgan, P.J., Lawson, W., Davidson, G. & Howell, H.E. (1989) Melatonin inhibits cyclic AMP production in cultured ovine pars tuberalis cells. J. Mol. Endocrinol., 3, 55-58.
35. van den Pol, A.N., Finkbeiner, S.M. & Cornell-Bell, A.H. (1992) Calcium excitability and oscillations in suprachiasmatic nucleus. J. Neurosci., 12, 2648-2664.
36. Reppert, S.M. & Weaver, D.R. (1996) Maternal entrainment of a foetal biological clock. In: Wetterberg, L. (ed.), Light and Biological Rhythms in Man. Pergamon, Oxford, pp. 93-104.
37. Reppert, S.M., Weaver, D.R. & Ebisawa, T. (1994) Cloning and characterisation of a mammalian melatonin receptor that mediates reproductive and circadian responses. Neuron, 13, 1177-1185.
38. Sheng, M., Dougan, S.T. & Greenberg, M.E. (1990) Membrane depolarisation and calcium induce c-fos transcription via phosphorylation of CREB. Neuron, 4, 571-582.
39. 2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science, 252, 1427-1430.
40. Smith, R.D., Turek, F.W. & Takahashi, J.S. (1992) Two families of phase-response curves characterise the resetting of the hamster circadian clock. Am. J. Physiol., 262, R1149-R1153.
41. Snodgrass, P. & Davis, F.C. (1995) Dopaminergic activation is a transient mechanism for entrainment in Syrian hamsters. The Physiologist, 38, A23 (Abstract).
42. 2+ channel activation regulates c-fos transcription at multiple levels. J. Biol. Chem., 270, 4224-4235.
43. Tominaga, K., Geusz, M.E., Michel, S. & Inouye, S.-I.T. (1994) Calcium imaging in organotypic cultures of the rat suprachiasmatic nucleus. Neuroreport, 5, 1901-1905.
44. Viswanathan, N. & Davis, F.C. (1997) Single prenatal injections of melatonin or the D1-dopamine receptor agonist SKF 38393 to pregnant hamsters sets the offsprings' circadian rhythms to phases 180 degree apart. J. Comp. Physiol. A, 180, 339-346.
45. Viswanathan, N., Weaver, D.R., Reppert, S.M. & Davis, F.C. (1994) Entrainment of the fetal circadian pacemaker by prenatal injections of the dopamine agonist SKF 38393. J. Neurosci., 14, 5393-5398.
46. 1b receptor is not necessary for reproductive and circadian responses to melatonin in Siberian hamsters. Molec. Endocrinol., 10, 1478-1487.
47. Welsh, D.K., Logothetis, D.E., Meister, M. & Reppert, S.M. (1995) Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron, 14, 697-706.