In vitro effects of resveratrol on the viability and infectivity of the microsporidian Encephalitozoon cuniculi

Antimicrobial Agents and Chemotherapy

Volumn 48, Issue 7, 2004, Pages 2497-2501

  Leiro, José ^a   Cano, Ernesto ^a   Ubeira, Florencio M ^a   Orallo, Francisco ^a   Sanmartín, Manuel L ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

RESVERATROL;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; DRUG ACTIVITY; DRUG EFFECT; ENCEPHALITOZOON CUNICULI; EPITHELIUM CELL; GRAPE; HOST CELL; IMMUNOCOMPETENCE; IN VITRO STUDY; MICROSPORIDA; NONHUMAN; PRIORITY JOURNAL; PROTOZOAL INFECTION; RED WINE; SPOROGENESIS;

ANIMALS; CELL LINE; CULTURE MEDIA; ENCEPHALITOZOON CUNICULI; HAPLORHINI; SPORES, PROTOZOAN; STILBENES; VASODILATOR AGENTS;

EID: 3042616985     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.48.7.2497-2501.2004     Document Type: Article

References (40)

1. Bacchi, C. J., S. Lane, L. M. Weiss, N. Yarlett, P. Takvorian, A. Cali, and M. Wittner. 2001. Polyamine synthesis and interconversion by the microsporidian Encephalitozoon cuniculi. J. Eukaryot. Microbiol. 48:374-381.
2. Bacchi, C. J., L. M. Weiss, S. Lane, B. Frydman, A. Valasinas, V. Reddy, J. S. Sun, L. J. Marton, I. A. Khan, M. Moretto, N. Yarlett, and M. Wittner. 2002. Novel synthetic polyamines are effective in the treatment of experimental microsporidiosis, an opportunistic AIDS-associated infection. Antimicrob. Agents Chemother. 46:55-61.
3. 2+ ions: implications for their antioxidant properties. Biochem. J. 330:1173-1178.
4. Burglin, T. R. 2003. The homeobox genes of Encephalitozoon cuniculi (Microsporidia) reveal a putative mating-type locus. Dev. Genes Evol. 213:50-52.
5. Chan, M. M. 2002. Antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin. Biochem. Pharmacol. 63:99-104.
6. Chung, K. T., T. Y. Wong, C. I. Wei, Y. W. Huang, and Y. Lin. 1998. Tannins and human health: a review. Crit. Rev. Food Sci. Nutr. 38:421-464.
7. Conteas C. N., O. G. Berlin, L. R. Ash, and J. S. Pruthi. 2000 Therapy for human gastrointestinal microsporidiosis. Am. J. Trop. Med. Hyg. 63:121-127.
8. Didier, E. S. 1997. Effects of albendazole, fumagillin, and TNP-470 on microsporidial replication in vitro. Antimicrob. Agents Chemother. 41:1541-1546.
9. Didier, E. S., K. F. Snowden, and J. A. Shadduck. 1998. Biology of microsporidian species infecting mammals. Adv. Parasitol. 40:283-320.
10. Dobrydneva, Y., R. L. Williams, and P. F. Blackmore. 1999. trans-resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br. J. Pharmacol. 128:149-157.
11. Fournier, S., O. Liguory, C. Sarfati, F. David-Ouaknine, F. Derouin, J. M. Decazes, and J. M. Molina. 2000. Disseminated infection due to Encephalitozoon cuniculi in a patient with AIDS: case report and review. HIV Med. 1:155-161.
12. Franssen, F. F., J. T. Lumeij, and F. van Knapen. 1995. Susceptibility of Encephalitozoon cuniculi to several drugs in vitro. Antimicrob. Agents Chemother. 39:1265-1268.
13. Fremont, L. 2000. Biological effects of resveratrol. Life Sci. 66:663-673.
14. He, Q., G. J. Leitch, G. S. Visvesvara, and S. Wallace. 1996. Effects of nifedipine, metronidazole, and nitric oxide donors on spore germination and cell culture infection of the microsporidia Encephalitozoon hellem and Encephalitozoon intestinalis. Antimicrob. Agents Chemother. 40:179-185.
15. Holmes-McNary, M., and A. S. Baldwin, Jr. 2000. Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IκB kinase. Cancer Res. 60:3477-3483.
16. Jeandet, P., A. C. Douillet-Breuil, R. Bessis, S. Debord, M. Sbaghi, and M. Adrian. 2002. Phytoalexins from the Vitaceae: biosynthesis, phytoalexin gene expression in transgenic plants, antifungal activity, and metabolism. J. Agric. Food Chem. 50:2731-2741.
17. Juan, M. E., M. P. Vinardell, and J. M. Planas. 2002. The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmful. J. Nutr. 132:257-260.
18. Keeling P. J., and N. M. Fast. 2002. Microsporidia: biology and evolution of highly reduced intracellular parasites. Annu. Rev. Microbiol. 56:93-116.
19. Kiderlen, A. F., O. Kayser, D. Ferreira, and H. Kolodziej. 2001. Tannins and related compounds: killing of amastigotes of Leishmania donovani and release of nitric oxide and tumour necrosis factor alpha in macrophages in vitro. Z. Naturforsch (C) 56:444-454.
20. Kotler, D. P., and J. M. Orenstein. 1998. Clinical syndromes associated with microsporidiosis. Adv. Parasitol. 40:321-349.
21. Lee, S. Y., C. Y. Kim, J. J. Lee, J. G. Jung, and S. R. Lee. 2003. Effects of delayed administration of (-)-epigallocatechin gallate, a green tea polyphenol on the changes in polyamine levels and neuronal damage after transient forebrain ischemia in gerbils. Brain Res. Bull. 61:399-406.
22. Leitch, G. J., Q. He, S. Wallace, and G. S. Visvesvara. 1993. Inhibition of the spore polar filament extrusion of the microsporidium, Encephalitozoon hellem, isolated from an AIDS patient. J. Eukaryot. Microbiol. 40:711-717.
23. Metenier, G., and C. P. Vivares. 2001. Molecular characteristics and physiology of microsporidia. Microbes Infect. 3:407-415.
24. Millership, J. J., C. Chappell, P. C. Okhuysen, and K. F. Snowden. 2002. Characterization of aminopeptidase activity from three species of microsporidia: Encephalitozoon cuniculi, Encephalitozoon hellem, and Vittaforma corneae. J. Parasitol. 88:843-848.
25. Molina, J. M., M. Tourneur, C. Sarfati, S. Chevret, A. de Gouvello, J. G. Gobert, S. Balkan, and F. Derouin. 2002. Fumagillin treatment of intestinal microsporidiosis. N. Engl. J. Med. 346:1963-1969.
26. Pannala, A. S., S. Singh, and C. Rice-Evans. 1999. Flavonoids as peroxynitrite scavengers in vitro. Method. Enzymol. 299:207-235.
27. Santillana-Hayat, M., C. Sarfati, S. Fournier, et al. 2002. Effects of chemical and physical agents on viability and infectivity of Encephalitozoon intestinalis determined by cell culture and flow cytometry. Antimicrob. Agents Chemother. 46:2049-2051.
28. Schneider, Y., P. Chabert, J. Stutzmann, D. Coelho, A. Fougerousse, F. Gosse, J. F. Launay, R. Brouillard, and F. Raul. 2003. Resveratrol analog (Z)-3,5,4′-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization. Int. J. Cancer. 107:189-196.
29. Schouten A, L. Wagemakers, F. L. Stefanato, R. M. van der Kaaij, and J. A. van Kan. 2002. Resveratrol acts as a natural profungicide and induces self-intoxication by a specific laccase. Mol. Microbiol. 43:883-894.
30. Shirataki, Y., N. Motohashi, S. Tani, H. Sakagami, K. Satoh, H. Nakashima, S. K. Mahapatra, K. Ganguly, S. G. Dastidar, and A. N. Chakrabarty. 2001. In vitro biological activity of prenylflavanones. Anticancer Res. 21:275-280.
31. Smith, A. H., J. A. Imlay, and R. I. Mackie. 2003. Increasing the oxidative stress response allows Escherichia coli to overcome inhibitory effects of codensed tannins. Appl. Environ. Microbiol. 69:3406-3411.
32. Snowden, K., K. Logan, and E. S. Didier. 1999. Encephalitozoon cuniculi strain III is a cause of encephalitozoonosis in both humans and dogs. J. Infect. Dis. 180:2086-2088.
33. Tapiero, H., K. D. Tew, B. G. Nguyen, and G. Mathe. 2002. Polyphenols: Do they play a role in the prevention of human pathologies? Biomed. Pharmacother. 56:200-207.
34. van Gool, T., and J. Dankert. 1995. Human microsporidiosis: clinical, diagnostic and therapeutic aspects of an increasing infection. Clin. Microbiol. Infect. 1:75-85.
35. Vivares, C. P., M. Gouy, F. Thomarat, and G. Metenier. 2002. Functional and evolutionary analysis of a eukaryotic parasitic genome. Curr. Opin. Microbiol. 5:499-505.
36. Wasson, K., and R. L. Peper. 2000. Mammalian microsporidiosis. Vet. Pathol. 37:113-128.
37. Weidner, E. 1982. The microsporidian spore invasion tube. III. Tube extrusion and assembly. Cell Biol. 93:976-979.
38. Weiss, L. M. 2001. Microsporidia: emerging pathogenic protists. Acta Trop. 78:89-102.
39. Wolter, F., L. Turchanowa, and J. Stein. 2003. Resveratrol-induced modification of polyamine metabolism is accompanied by induction of c-Fos. Carcinogenesis 24:469-474.
40. Xiao, L., L., Li, G. S. Visvesvara, H. Moura, E. S. Didier, and A. A. Lai. 2001. Genotyping Encephalitozoon cuniculi by multilocus analyses of genes with repetitive sequences. J. Clin. Microbiol. 39:2248-2253.