Structural convergence of antibody binding of carbohydrate determinants in Lewis Y tumor antigens

Journal of Molecular Biology

Volumn 340, Issue 4, 2004, Pages 809-818

  Ramsland, Paul A ^a   Farrugia, William ^a   Bradford, Tessa M ^a   Hogarth, P Mark ^a   Scott, Andrew M ^b  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

Author keywords

ADCC, antibody dependent cellular cytotoxicity; antibody crystallography; cancer treatments; carbohydrate antigens; CDC, complement dependent cytotoxicity; CDR, complementarity determining regions; D, diversity minigene; humanized antibody; tumor targeting

Indexed keywords

CARBOHYDRATE; CARBOHYDRATE DERIVATIVE; DISACCHARIDE; EPITOPE; GALACTOSE; IMMUNOGLOBULIN F(AB) FRAGMENT; SOLVENT; TUMOR ANTIGEN;

ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; BLOOD GROUP TYPING; CARCINOMA; CRYSTAL STRUCTURE; IMMUNOTHERAPY; PRIORITY JOURNAL;

EID: 3042561937     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.05.037     Document Type: Article

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