-
1
-
-
0037030412
-
Therapeutic antibodies: Magic bullets hit the target
-
Gura T. Therapeutic antibodies: magic bullets hit the target. Nature. 417:2002;584-586.
-
(2002)
Nature
, vol.417
, pp. 584-586
-
-
Gura, T.1
-
2
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G., Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 256:1975;495-497.
-
(1975)
Nature
, vol.256
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
3
-
-
0025978976
-
Man-made antibodies
-
Winter G., Milstein C. Man-made antibodies. Nature. 349:1991;293-299.
-
(1991)
Nature
, vol.349
, pp. 293-299
-
-
Winter, G.1
Milstein, C.2
-
4
-
-
0032826180
-
Signaling antibodies in cancer therapy
-
Cragg M.S., et al. Signaling antibodies in cancer therapy. Curr. Opin. Immunol. 11:1999;541-547.
-
(1999)
Curr. Opin. Immunol.
, vol.11
, pp. 541-547
-
-
Cragg, M.S.1
-
5
-
-
0031106547
-
Clinical significance of IgG Fc receptors and Fc gamma-directed immunotherapies
-
Deo Y.M., et al. Clinical significance of IgG Fc receptors and Fc gamma-directed immunotherapies. Immunol. Today. 18:1997;127-135.
-
(1997)
Immunol. Today
, vol.18
, pp. 127-135
-
-
Deo, Y.M.1
-
7
-
-
0036900286
-
Antibody discovery: The use of transgenic mice to generate human monoclonal antibodies for therapeutics
-
Kellermann S.A., Green L.L. Antibody discovery: the use of transgenic mice to generate human monoclonal antibodies for therapeutics. Curr. Opin. Biotechnol. 13:2002;593-597.
-
(2002)
Curr. Opin. Biotechnol.
, vol.13
, pp. 593-597
-
-
Kellermann, S.A.1
Green, L.L.2
-
8
-
-
0028222932
-
Antigen-specific human antibodies from mice comprising four distinct genetic modifications
-
Lonberg N., et al. Antigen-specific human antibodies from mice comprising four distinct genetic modifications. Nature. 368:1994;856-859.
-
(1994)
Nature
, vol.368
, pp. 856-859
-
-
Lonberg, N.1
-
10
-
-
0036962407
-
Treating Crohn's disease by inducing T lymphocyte apoptosis
-
Van Den Brande J.M., et al. Treating Crohn's disease by inducing T lymphocyte apoptosis. Ann. N. Y. Acad. Sci. 973:2002;166-180.
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.973
, pp. 166-180
-
-
Van Den Brande, J.M.1
-
11
-
-
0030974933
-
Role of complement in inflammation and injury in the nervous system
-
Morgan B.P., et al. Role of complement in inflammation and injury in the nervous system. Exp. Clin. Immunogenet. 14:1997;19-23.
-
(1997)
Exp. Clin. Immunogenet.
, vol.14
, pp. 19-23
-
-
Morgan, B.P.1
-
12
-
-
0034997865
-
Targeting complement in therapy
-
Kirschfink M. Targeting complement in therapy. Immunol. Rev. 180:2001;177-189.
-
(2001)
Immunol. Rev.
, vol.180
, pp. 177-189
-
-
Kirschfink, M.1
-
13
-
-
0036952617
-
Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of non-myeloablative conditioning?
-
Hale G., et al. Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of non-myeloablative conditioning? Bone Marrow Transplant. 30:2002;797-804.
-
(2002)
Bone Marrow Transplant.
, vol.30
, pp. 797-804
-
-
Hale, G.1
-
14
-
-
0027194472
-
Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis
-
Xia M.Q., et al. Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis. Biochem. J. 293:1993;633-640.
-
(1993)
Biochem. J.
, vol.293
, pp. 633-640
-
-
Xia, M.Q.1
-
15
-
-
0037362016
-
Monoclonal antibodies combined to chemotherapy for the treatment of patients with lymphoma
-
Coiffier B. Monoclonal antibodies combined to chemotherapy for the treatment of patients with lymphoma. Blood Rev. 17:2003;25-31.
-
(2003)
Blood Rev.
, vol.17
, pp. 25-31
-
-
Coiffier, B.1
-
17
-
-
0028127935
-
Lymphoma regression induced by monoclonal anti-idiotypic antibodies correlates with their ability to induce Ig signal transduction and is not prevented by tumour expression of high levels of bcl-2 protein
-
Vuist W.M., et al. Lymphoma regression induced by monoclonal anti-idiotypic antibodies correlates with their ability to induce Ig signal transduction and is not prevented by tumour expression of high levels of bcl-2 protein. Blood. 83:1994;899-906.
-
(1994)
Blood
, vol.83
, pp. 899-906
-
-
Vuist, W.M.1
-
18
-
-
0032529703
-
Anti-idiotype antibodies can induce long-term complete remissions in non-Hodgkin's lymphoma without eradicating the malignant clone
-
Davis T.A., et al. Anti-idiotype antibodies can induce long-term complete remissions in non-Hodgkin's lymphoma without eradicating the malignant clone. Blood. 92:1998;1184-1190.
-
(1998)
Blood
, vol.92
, pp. 1184-1190
-
-
Davis, T.A.1
-
19
-
-
0033855859
-
Clinical trials of antibody therapy
-
Glennie M.J., Johnson P.W. Clinical trials of antibody therapy. Immunol. Today. 21:2000;403-410.
-
(2000)
Immunol. Today
, vol.21
, pp. 403-410
-
-
Glennie, M.J.1
Johnson, P.W.2
-
20
-
-
0035204468
-
New strategies for vaccination and imunomodulation in NHL
-
Stevenson F.K., et al. New strategies for vaccination and imunomodulation in NHL. Ann. Hematol. 80:(Suppl. 3):2001;B132-B134.
-
(2001)
Ann. Hematol.
, vol.80
, Issue.SUPPL. 3
, pp. 132-B134
-
-
Stevenson, F.K.1
-
21
-
-
19044380618
-
Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumour growth
-
Agus D.B., et al. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumour growth. Cancer Cell. 2:2002;127-137.
-
(2002)
Cancer Cell
, vol.2
, pp. 127-137
-
-
Agus, D.B.1
-
22
-
-
0029947568
-
Enhancement of antitumour immunity by CTLA-4 blockade
-
Leach D.R., et al. Enhancement of antitumour immunity by CTLA-4 blockade. Science. 271:1996;1734-1736.
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
-
23
-
-
17944364189
-
Elucidating the autoimmune and antitumour effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: Comparison of prophylaxis and therapy
-
Van Elsas A., et al. Elucidating the autoimmune and antitumour effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy. J. Exp. Med. 194:2001;481-489.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 481-489
-
-
Van Elsas, A.1
-
24
-
-
0037087379
-
T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibody
-
Tutt A.L., et al. T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibody. J. Immunol. 168:2002;2720-2728.
-
(2002)
J. Immunol.
, vol.168
, pp. 2720-2728
-
-
Tutt, A.L.1
-
25
-
-
0034218442
-
Rejection of disseminated metastases of colon carcinoma by synergism of IL-12 gene therapy and 4-1BB costimulation
-
Chen S.H., et al. Rejection of disseminated metastases of colon carcinoma by synergism of IL-12 gene therapy and 4-1BB costimulation. Mol. Ther. 2:2000;39-46.
-
(2000)
Mol. Ther.
, vol.2
, pp. 39-46
-
-
Chen, S.H.1
-
26
-
-
0037103147
-
4-1BB-specific monoclonal antibody promotes the generation of tumour- specific immune responses by direct activation of CD8 T cells in a CD40- dependent manner
-
Miller R.E., et al. 4-1BB-specific monoclonal antibody promotes the generation of tumour- specific immune responses by direct activation of CD8 T cells in a CD40- dependent manner. J. Immunol. 169:2002;1792-1800.
-
(2002)
J. Immunol.
, vol.169
, pp. 1792-1800
-
-
Miller, R.E.1
-
27
-
-
0003311698
-
MDX-010 (human anti-CTLA4): A phase I clinical trial in malignant melanoma
-
Tchekmedyian S., et al. MDX-010 (human anti-CTLA4): a phase I clinical trial in malignant melanoma. Am. Soc. Clin. Oncol. Proc. 1:2002;1.
-
(2002)
Am. Soc. Clin. Oncol. Proc.
, vol.1
, pp. 1
-
-
Tchekmedyian, S.1
-
28
-
-
0033432773
-
Coupling and uncoupling of tumour immunity and autoimmunity
-
Bowne W.B., et al. Coupling and uncoupling of tumour immunity and autoimmunity. J. Exp. Med. 190:1999;1717-1722.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1717-1722
-
-
Bowne, W.B.1
-
29
-
-
0033571105
-
Induction of tumour immunity by removing CD25+CD4+ T cells: A common basis between tumour immunity and autoimmunity
-
Shimizu J., et al. Induction of tumour immunity by removing CD25+CD4+ T cells: a common basis between tumour immunity and autoimmunity. J. Immunol. 163:1999;5211-5218.
-
(1999)
J. Immunol.
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
-
30
-
-
0034547959
-
Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cells
-
Carpenter P.A., et al. Non-Fc receptor-binding humanized anti-CD3 antibodies induce apoptosis of activated human T cells. J. Immunol. 165:2000;6205-6213.
-
(2000)
J. Immunol.
, vol.165
, pp. 6205-6213
-
-
Carpenter, P.A.1
-
31
-
-
0036670565
-
Engineering therapeutic antibodies for improved function
-
Presta L.G., et al. Engineering therapeutic antibodies for improved function. Biochem. Soc. Trans. 30:2002;487-490.
-
(2002)
Biochem. Soc. Trans.
, vol.30
, pp. 487-490
-
-
Presta, L.G.1
-
32
-
-
0033966576
-
In vivo enhancement of tumour radioresponse by C225 antiepidermal growth factor receptor antibody
-
Milas L., et al. In vivo enhancement of tumour radioresponse by C225 antiepidermal growth factor receptor antibody. Clin. Cancer Res. 6:2000;701-708.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 701-708
-
-
Milas, L.1
-
33
-
-
0036094194
-
Enhanced antitumour activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumour xenografts
-
Prewett M.C., et al. Enhanced antitumour activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumour xenografts. Clin. Cancer Res. 8:2002;994-1003.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 994-1003
-
-
Prewett, M.C.1
-
34
-
-
0035254521
-
Head and neck cancer as a clinical model for molecular targeting of therapy: Combining EGFR blockade with radiation
-
Harari P.M., Huang S-H. Head and neck cancer as a clinical model for molecular targeting of therapy: combining EGFR blockade with radiation. Int. J. Radiat. Oncol. Biol. Phys. 49:2001;427-433.
-
(2001)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.49
, pp. 427-433
-
-
Harari, P.M.1
Huang, S.-H.2
-
35
-
-
0036605053
-
Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-B and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines
-
Bancroft C.C., et al. Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF-B and AP-1 activation and IL-8 and VEGF expression in human head and neck squamous cell carcinoma lines. Int. J. Cancer. 99:2002;538-548.
-
(2002)
Int. J. Cancer
, vol.99
, pp. 538-548
-
-
Bancroft, C.C.1
-
36
-
-
0034477864
-
Therapeutic uses of MAbs directed against CD20
-
Vose J.M. Therapeutic uses of MAbs directed against CD20. Cytotherapy. 2:2000;455-461.
-
(2000)
Cytotherapy
, vol.2
, pp. 455-461
-
-
Vose, J.M.1
-
37
-
-
0033925354
-
Immunotoxins and vascular leak syndrome
-
Vitetta E.S. Immunotoxins and vascular leak syndrome. Cancer J. 6:(Suppl. 3):2000;S218-S224.
-
(2000)
Cancer J.
, vol.6
, Issue.SUPPL. 3
, pp. 218-S224
-
-
Vitetta, E.S.1
-
38
-
-
0037102128
-
Radiolabeled anti-CD20 monoclonal antibodies for the treatment of B- cell lymphoma
-
Dillman R.O. Radiolabeled anti-CD20 monoclonal antibodies for the treatment of B- cell lymphoma. J. Clin. Oncol. 20:2002;3545-3557.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 3545-3557
-
-
Dillman, R.O.1
-
39
-
-
0030825191
-
Immunotoxins for the treatment of B-cell lymphomas
-
Ghetie M.A., et al. Immunotoxins for the treatment of B-cell lymphomas. Mol. Med. 3:1997;420-427.
-
(1997)
Mol. Med.
, vol.3
, pp. 420-427
-
-
Ghetie, M.A.1
|