The three-dimensional structure of a complex of a murine Fab (NC10.14) with a potent sweetener (NC174): An illustration of structural diversity in antigen recognition by immunoglobulins

Journal of Molecular Biology

Volumn 302, Issue 4, 2000, Pages 853-872

  Guddat, Luke W ^a,b,c   Shan, Lin ^a   Broomell, Christopher ^a   Ramsland, Paul A ^a   Fan, Zhao Chang ^a   Anchin, Jerry M ^b   Linthicum, D Scott ^b   Edmundson, Allen B ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Anti sweetener Fab; Antigen recognition; Antigen antibody complex; Crystal structure; Receptor mimicry

Indexed keywords

ACETIC ACID; ARGININE; BIPHENYL; HAPTEN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; SWEETENING AGENT; TRYPTOPHAN; TYROSINE;

ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; HYDROGEN BOND; HYDROPHOBICITY; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

MURINAE;

EID: 0034730393     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4083     Document Type: Article

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