Recombinant adenovirus vaccines can successfully elicit CD8+ T cell immunity under conditions of extreme leukopenia

Molecular Therapy

Volumn 13, Issue 2, 2006, Pages 270-279

  Grinshtein, Natalie ^a   Yang, Teng Chih ^a   Parsons, Robin ^a   Millar, James ^a   Denisova, Galina ^a   Dissanayake, Dilan ^a   Leitch, Jaina ^a   Wan, Yonghong ^a   Bramson, Jonathan ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Gene therapy; Leukopenia; T cells; Vaccination; Viral

Indexed keywords

CD8 ANTIGEN; VIRUS VACCINE;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELL COMPARTMENTALIZATION; CELL PROLIFERATION; CELL TYPE; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; DRUG EFFICACY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOGENICITY; IMMUNOTHERAPY; LEUKOPENIA; MOUSE; NONHUMAN; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE ACTIVATION;

ADENOVIRIDAE; ANIMALS; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; FEMALE; LEUKOPENIA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RADIATION CHIMERA; VACCINES, SYNTHETIC; VIRAL VACCINES; WHOLE-BODY IRRADIATION;

ADENOVIRIDAE; ANIMALIA;

EID: 30344483223     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2005.09.018     Document Type: Article

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