S-phase arrest by reactive nitrogen species is bypassed by okadaic acid, an inhibitor of protein phosphatases PP1/PP2A

Free Radical Biology and Medicine

Volumn 40, Issue 2, 2006, Pages 247-259

  Ranjan, Priya ^a   Heintz, Nicholas H ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

C10 cells; Cell cycle checkpoint; Free radicals; Okadaic acid; Oxidative stress; Retinoblastoma protein

Indexed keywords

ADOZELESIN; ATM PROTEIN; CELL CYCLE PROTEIN 6; CISPLATIN; CYCLIN D1; LINSIDOMINE; NITROGEN DIOXIDE; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN P21; REACTIVE NITROGEN SPECIES; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE S PHASE; CELL NUCLEUS; CONTROLLED STUDY; DEPHOSPHORYLATION; DNA DAMAGE; DNA SYNTHESIS; DRUG INHIBITION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CDC25 PHOSPHATASE; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELLS, CULTURED; CISPLATIN; CYCLIN D1; DNA; DNA DAMAGE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MOLSIDOMINE; NITROGEN DIOXIDE; NUCLEAR PROTEINS; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; REACTIVE NITROGEN SPECIES; REPLICATION PROTEIN C; RETINOBLASTOMA PROTEIN; S PHASE; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; MAMMALIA;

EID: 30344455039     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2005.08.049     Document Type: Article

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