Notch signals control the fate of immature progenitor cells in the intestine;Notch, un gène clé de l'équilibre entre prolifération et différenciation des cellules épithé liales de l'intestin

Medecine/Sciences

Volumn 21, Issue 8-9, 2005, Pages 780-781

  Robine, Sylvie ^a   Fre, Silvia ^b   Huyghe, Mathilde ^a   Artavanis Tsakonas, Spyros ^b,c   Louvard, Daniel ^a  

^a INSTITUT CURIE   (France)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c Centre de Recherche Interdisciplinaire en Biologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; CRE RECOMBINASE; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; KI 67 ANTIGEN; NOTCH RECEPTOR; NOTCH1 RECEPTOR;

CELL DIFFERENTIATION; CELL FATE; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; INTESTINE CELL; INTESTINE CRYPT; NOTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STEM CELL;

EID: 30344437992     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/2005218-9780     Document Type: Note

References (8)

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2. Fre S, Huyghe M, Mourikis P, Robine S, Louvard D, Artavanis-Tsakonas S. Notch signals control the fate of immature progenitor cells in the intestine. Nature 2005; 435: 964-8.
3. Van Es JH, Van Gijn ME, Riccio O, et al. Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and neoplasia into Goblet cells. Nature 2005; 435: 959-63.
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