Association of fragile site-associated (FSA) gene expression with epithelial differentiation and tumor development

Biochemical and Biophysical Research Communications

Volumn 340, Issue 3, 2006, Pages 887-893

  Kuo, M Tien ^a   Wei, Yingjie ^a   Yang, Xinlin ^a   Tatebe, Shigeru ^a   Liu, Jinsong ^a   Troncoso, Patricia ^a   Sahin, Aysegul ^a   Ro, Jae Y ^a   Hamilton, Stanly R ^a   Savaraj, Niramol ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Epithelial cell differentiation; Fragile site; Immunohistochemistry; RNA in situ hybridization; Tumor development

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CONTROLLED STUDY; EPITHELIUM CELL; FRAGILE SITE ASSOCIATED GENE; GENE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MAMMARY GLAND; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPERMATOGENESIS; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BIOTINYLATION; BLOTTING, WESTERN; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CHROMOSOME FRAGILE SITES; DNA, COMPLEMENTARY; DOWN-REGULATION; EPITHELIAL CELLS; EPITHELIUM; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MAMMARY GLANDS, ANIMAL; MICE; MITOSIS; OPEN READING FRAMES; P-GLYCOPROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TISSUE DISTRIBUTION; TRANSFECTION;

ANIMALIA; CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 30144443189     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.12.088     Document Type: Article

References (20)

1. R.I. Richards Fragile and unstable chromosomes in cancer: causes and consequences Trends Genet. 17 2001 339 345
2. T.W. Glover, Common fragile sites, Cancer Lett. (2005) 1-9 (in press).
3. M.T. Kuo, R.C. Vyas, L.X. Jiang, and W.N. Hittelman Chromosomal breakage at a major fragile site associated with P-glycoprotein gene amplification in multidrug-resistant CHO cells Mol. Cell. Biol. 14 1994 5202 5211
4. A. Coquelle, E. Pipiras, F. Toledo, G. Buttin, and M. Debatisse Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons Cell 89 1997 215 225
5. A. Hellman, E. Zlotorynski, S.W. Sherer, J. Cheung, J.B. Vincent, S. Vincent, D.I. Smith, L. Trakhtenbrot, and B. Kerem A role for common fragile site induction in amplification of human oncogenes Cancer Cell 1 2002 89 97
6. M. Ciullo, M.A. Debily, L. Rozier, M. Autiero, A. Billaul, V. Mayau, S. El Marhomy, J. Guardiola, A. Bernheim, P. Coullin, D. Piatier-Tonneau, and M. Debatisse Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I Hum. Mol. Genet. 11 2002 2887 2894
7. D.B. Zimonjic, M.E. Durkin, and C.L. Keck-Waggoner Arrangements, copy number, and amplification at fragile site FRA5C in human hepatocellular carcinoma Neoplasia 5 2003 390 396
8. Y. Wei, Y.-C. Lin-Lee, X. Yang, W. Dai, S. Zhao, F.V. Rassool, G.W. Elgart, L. Feun, M.T. Kuo, Molecular cloning of CHO 1q31 chromosomal fragile site DNA that is important to mdr1 gene amplification reveals a novel gene whose expression is associated with spermatocyte and adipocyte differentiation, Gene (in press).
9. R.M. McKay, J.P. McKay, L. Avery, and J.M. Graff Caenorhabditis elegans: a model for exploring the genetics of fat storage Dev. Cell 4 2003 131 142
10. S. Tatebe, H. Unate, F.A. Sinicrope, T. Sakatani, K. Sugamura, M. Makino, H. Ito, N. Savaraj, N. Kaibara, and M.T. Kuo Expression of heavy subunit of gamma-glutamylcysteine synthetase (gamma-GCSh) in human colorectal carcinoma Int. J. Cancer 97 2002 21 27
11. I.M. Song, N. Savaraj, Z.H. Siddik, P. Liu, Y. Wei, C.J. Wu, and M.T. Kuo Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells Mol. Cancer Ther. 3 2004 1543 1549
12. W.F. Symmans, D.J. Fiterman, S.K. Anderson, M. Ayers, R. Rouzier, V. Dunmire, J. Stec, V. Valero, N. Sneige, C. Albarracin, Y. Wu, J.S. Rooos, P. Wagner, R.L. Theriault, B. Arun, H. Kuerer, K.R. Hess, W. Zhang, G.N. Hortobagyi, and L. Pusztai A single-gene biomarker identifies breast cancers associated with immature cell type and short duration of prior breastfeeding Endocr. Relat. Cancer 12 2005 1059 1069
13. H. Cheng, and C.P. Leblond Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types Am. J. Anat. 141 1974 537 561
14. J.C. Mills, and J.I. Gordon The intestinal stem cell niche: there grows the neighborhood Proc. Natl. Acad. Sci. USA 98 2001 12334 12336
15. D.M. Owens, and F.M. Watt Contribution of stem cells and differentiated cells to epidermal tumors Nat. Rev. Cancer 3 2002 444 451
16. L. Hennighausen Information networks in the mammary gland Nat. Rev. Mol. Cell Biol. 6 2005 715 725
17. B.T. Estes, J.M. Gimble, and F. Guilak Mechanical signals as regulators of stem cell fate Curr. Top. Dev. Biol. 60 2004 91 126
18. F. Schock, and N. Perrimon Molecular mechanisms of epithelial morphogenesis Annu. Rev. Cell Dev. Biol. 18 2002 463 493
19. J.M.W. Slack Stem cells in epithelial tissues Science 287 2000 1431 1433
20. R.A. DePinho The age of cancer Nature 408 2000 248 254