A single-gene biomarker identifies breast cancers associated with immature cell type and short duration of prior breastfeeding

Endocrine-Related Cancer

Volumn 12, Issue 4, 2005, Pages 1059-1069

  Symmans, W F ^a   Fiterman, D J ^a   Anderson, S K ^a   Ayers, M ^b   Rouzier, R ^a   Dunmire, V ^a   Stec, J ^b   Valero, V ^a   Sneige, N ^a   Albarracin, C ^a   Wu, Y ^a   Ross, J S ^b,c   Wagner, P ^a   Theriault, R L ^a   Arun, B ^a   Kuerei, H ^a   Hess, K R ^a   Zhang, W ^a   Hortobagyi, G N ^a   Pusztai, L ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c ALBANY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; BIOLOGICAL MARKER;

AGE DISTRIBUTION; ARTICLE; BREAST CANCER; BREAST FEEDING; CANCER GRADING; CELL MATURATION; CELL TYPE; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC VALUE; DNA MICROARRAY; ETHNOLOGY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; PHENOTYPE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

BREAST FEEDING; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN; RECEPTORS, GABA-A; TUMOR MARKERS, BIOLOGICAL;

EID: 29144510244     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/erc.1.01051     Document Type: Article

References (59)

1. Abd El-Rehim DM, Pinder SE, Paish CE, Bell J, Blarney RW, Robertson JF, Nicholson RI & Ellis IO 2004 Expression of luminal and basal cytokeratins in human breast carcinoma. Journal of Pathology 203 661-671.
2. Baghestanian M, Jordan JH, Kiener HP, Bevec D, Agis H, Fritsch G, Muller MR, Bankl HC, Schernthaner GH, Lechner K et al. 2002 Activation of human mast cells through stem cell factor receptor (KIT) is associated with expression of bcl-2. International Archives in Allergy and Immunology 129 228-236.
3. Bentley JR, Delfino RJ, Taylor TH, Howe S & Anton-Culver H 1998 Differences in breast cancer stage at diagnosis between non-Hispanic white and Hispanic populations, San Diego County 1988-1993. Breast Cancer Research and Treatment 50 1-9.
4. Bocker W, Moll R, Poremba C, Holland R, Van Diest PJ, Dervan P, Burger H, Wai D, Ina Diallo R, Brandt B et al. 2002 Common adult stem cells in the human breast give rise to glandular and myoepithelial cell lineages: a new cell biological concept. Laboratory Investigations 82 737-746.
5. Boyer-Chammard A, Taylor TH & Anton-Culver H 1999 Survival differences in breast cancer among racial/ethnic groups: a population-based study. Cancer Detection and Prevention 23 463-473.
6. Chen Y, Stump RJ, Lovicu FJ & McAvoy JW 2004 Expression of frizzleds and secreted frizzled-related proteins (Sfrps) during mammalian lens development. International Journal of Developmental Biology 48 867-877.
7. Clarke CL, Sandle J, Parry SC, Reis-Filho JS, O'Hare MJ & Lakhani SR 2004 Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype. Journal of Pathology 204 147-152.
8. Collaborative Group 2002 Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50302 women with breast cancer and 96973 women without the disease. Lancet 360 187-195.
9. Daly MB, Clark GM & McGuire WL 1985 Breast cancer prognosis in a mixed Caucasian-Hispanic population. Journal of the National Cancer Institute 74 753-757.
10. Elledge RM, Clark GM, Chamness GC & Osborne CK 1994 Tumor biologic factors and breast cancer prognosis among white, Hispanic, and black women in the United States. Journal of the National Cancer Institute 86 705-712.
11. Elledge RM, Green S, Pugh R, Allred DC, Clark GM, Hill J, Ravdin P, Martino S & Osborne CK 2000 Estrogen receptor (ER) and progesterone receptor (PgR), by ligand-binding assay compared with ER, PgR and pS2, by immuno-histochemistry in predicting response to tamoxifen in metastatic breast cancer: a Southwest Oncology Group Study. International Journal of Cancer 89 111-117.
12. Enger SM, Ross RK, Henderson B & Bernstein L 1997 Breastfeeding history, pregnancy experience and risk of breast cancer. British Journal of Cancer 76 118-123.
13. Foulkes WD, Stefansson IM, Chappuis PO, Begin LR, Goffin JR, Wong N, Trudel M & Akslen LA 2003 Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. Journal of the National Cancer Institute 95 1482-1485.
14. Foulkes WD, Brunet JS, Stefansson IM, Straume O, Chappuis PO, Begin LR, Hamel N, Goffin JR, Wong N, Trudel M et al. 2004 The prognostic implication of the basal-like (cyclin E high/p27 low/p53 + /glomeruloid-microvascular- proliferation +) phenotype of BRCA1-related breast cancer. Cancer Research 64 830-835.
15. Fujii E & Mellon SH 2001 Regulation of uterine gamma-aminobutyric acid A receptor subunit expression throughout pregnancy. Endocrinology 142 1770-1777.
16. Gilliland FD, Hunt WC, Baumgartner KB, Crumley D, Nicholson CS, Fetherolf J & Samet JM 1998 Reproductive risk factors for breast cancer in Hispanic and non-Hispanic white women: the New Mexico Women's Health Study. American Journal of Epidemiology 148 683-692.
17. Han X & Amar S 2004 Secreted frizzled-related protein 1 (SFRP1) protects fibroblasts from ceramide-induced apoptosis. Journal of Biological Chemistry 279 2832-2840.
18. Harvey JM, Clark GM, Osborne CK & Allred DC 1999 Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. Journal of Clinical Oncology 17 1474-1481.
19. Hedblom E & Kirkness EF 1997 A novel class of GABAA receptor subunit in tissues of the reproductive system, Journal of Biological Chemistry 272 15346-15350.
20. Hedeen AN & White E 2001 Breast cancer size and stage in Hispanic American women, by birthplace: 1992-1995. American Journal of Public Health 91 122-125.
21. Hedenfalk I, Duggan D, Chen Y, Radmacher M, Bittner M, Simon R, Meltzer P, Gusterson B, Esteller M, Kallioniemi OP et al. 2001 Gene-expression profiles in hereditary breast cancer. New England Journal of Medicine 344 539-548.
22. Hildreth NG, Kelsey JL, Eisenfeld AJ, LiVolsi VA, Holford TR & Fischer DB 1983 Differences in breast cancer risk factors according to the estrogen receptor level of the tumor. Journal of the National Cancer Institute 70 1027-1031.
23. Huang WY, Newman B, Millikan RC, Conway K, Hulka BS, Schell MJ & Liu ET 2000 Risk of breast cancer according to the status of HER-2/neu oncogene amplification. Cancer Epidemiology, Biomarkers and Prevention 9 65-71.
24. Hulboy DL, Gautam S, Fingleton B & Matrisian LM 2004 The influence of matrix metalloproteinase-7 on early mammary tumorigenesis in the multiple intestinal neoplasia mouse. Oncology Reports 12 13-17.
25. Hunter CP 2000 Epidemiology, stage at diagnosis, and tumor biology of breast carcinoma in multiracial and multiethnic populations. Cancer 88, 1193-1202.
26. Jernstrom H, Lubinski J, Lynch HT, Ghadirian P, Neuhausen S, Isaacs C, Weber BL, Horsman D, Rosen B, Foulkes WD et al. 2004 Breast-feeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Journal of the National Cancer Institute 96 1094-1098.
27. Jiang Y, Harlocker SL, Molesh DA, Dillon DC, Stolk JA, Houghton RL, Repasky EA, Badaro R, Reed SG & Xu J 2002 Discovery of differentially expressed genes in human breast cancer using subtracted cDNA libraries and cDNA microarrays. Oncogene 21 2270-2282.
28. Kitoh T, Yanai H, Saitoh Y, Nakamura Y, Matsubara Y, Kitoh H, Yoshida T & Okita K 2004 Increased expression of matrix metalloproteinase-7 in invasive early gastric cancer. Journal of Gastroenterology 39 434-440.
29. Laurie DJ, Wisden W & Seeburg PH 1992 The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development. Journal of Neuroscience 12 4151-4172.
30. Leimeister C, Bach A & Gessler M 1998 Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family. Mechanisms of Development 75 29-42.
31. Li C & Hung Wong W 2001 Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application. Genome Biology 2 RESEARCH0032.
32. Lipworth L, Bailey LR & Trichopoulos D 2000 History of breast-feeding in relation to breast cancer risk: a review of the epidemiologic literature. Journal of the National Cancer Institute 92 302-312.
33. Majewska MD, Falkay G & Baulieu EE 1989 Modulation of uterine GABAA receptors during gestation and by tetrahydroprogesterone. European Journal of Pharmacology 174 43-47.
34. Mandelblatt J, Andrews H, Kerner J, Zauber A & Burnett W 1991 Determinants of late stage diagnosis of breast and cervical cancer: the impact of age, race, social class, and hospital type. American Journal of Public Health 81, 646-649.
35. Mayberry RM & Stoddard-Wright C 1992 Breast cancer risk factors among black women and white women: similarities and differences. American Journal of Epidemiology 136 1445-1456.
36. McTiernan A, Thomas DB, Johnson LK & Roseman D 1986 Risk factors for estrogen receptor-rich and estrogen receptor-poor breast cancers. Journal of the National Cancer Institute 77 849-854.
37. Montgomery AC, McClelland RA, Skilton RA & Easton D 1985 Risk factors and clinical data related to oestrogen receptor status in women presenting with breast cancer. British Journal of Surgery 72 629-633.
38. Narayanan V, Olinsky S, Dahle E, Naidu S & Zoghbi HY 1998 Mutation analysis of the M6b gene in patients with Rett syndrome. American Journal of Medical Genetics 78 165-168.
39. Natarajan N, Nemoto T, Mettlin C & Murphy GP 1985 Race-related differences in breast cancer patients. Results of the 1982 national survey of breast cancer by the American College of Surgeons. Cancer 56 1704-1709.
40. Neelands TR & Macdonald RL 1999 Incorporation of the pi subunit into functional gamma-aminobutyric acid(A) receptors. Molecular Pharmacology 56 598-610.
41. Newcomb PA 1997 Lactation and breast cancer risk. Journal of Mammary Gland Biology and Neoplasia 2 311-318.
42. Nielsen TO, Hsu FD, Jensen K, Cheang M, Karaca G, Hu Z, Hernandez-Boussard T, Livasy C, Cowan D, Dressler L et al. 2004 Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clinical Cancer Research 10 5367-5374.
43. Ogura H, Akiyama F, Kasumi F, Kazui T & Sakamoto G 2003 Evaluation of HER-2 status in breast carcinoma by fluorescence in situ hybridization and immunohistochemistry. Breast Cancer 10 234-240.
44. Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA et al. 2000a Molecular portraits of human breast tumours. Nature 406 747-752.
45. Perou CM, Sùrlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA et al. 2000b Molecular portraits of human breast tumours. Nature 406 747-752.
46. Purwanto H, Sadjimin T & Dwiprahasto I 2000 Lactation and the risk of breast cancer. Gan To Kagaku Ryoho 27 (Suppl 2) 474-481.
47. Pusztai L, Ayers M, Stec J, Clark E, Hess K, Stivers D, Damokosh A, Sneige N, Buchholz TA, Esteva FJ et al. 2003 Gene expression profiles obtained from single passage fine needle aspirations (FNA) of breast cancer reliably identify prognostic/predictive markers such as estrogen (ER) and HER-2 receptor status and reveal large scale molecular differences between ER-negative and ER-positive tumors. Clinical Cancer Research 9 2406-2415.
48. Russo J & Russo IH 1994 Toward a physiological approach to breast cancer prevention. Cancer Epidemiology, Biomarkers and Prevention 3 353-364.
49. Sapino A, Coccorullo Z, Cassoni P, Ghisolfi G, Gugliotta P, Bongiovanni M, Arisio R, Crafa P & Bussolati G 2003 Which breast carcinomas need HER-2/neu gene study after immunohistochemical analysis? Results of combined use of antibodies against different c-erbB2 protein domains. Histopathology 43 354-362.
50. Smith GH, Mehrel T & Roop DR 1990 Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium. Cell Growth Differentiation 1 161-170.
51. Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS et al. 2001 Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. PNAS 98 10869-10874.
52. Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S et al. 2003 Repeated observation of breast tumor subtypes in independent gene expression data sets. PNAS 100 8418-8423.
53. Suarez-Rodriguez R & Belkind-Gerson J 2004 Cultured nestin-positive cells from postnatal mouse small bowel differentiate ex vivo into neurons, glia, and smooth muscle. Stem Cells 22 1373-1385.
54. Symmans WF, Ayers M, Clark EA, Stec J, Hess KR, Sneige N, Buchholz TA, Krishnamurthy S, Ibrahim NK, Buzdar AU et al. 2003 Total RNA yield and microarray gene expression profiles from fine needle aspiration and core needle biopsy samples of breast cancer. Cancer 97 2960-2971.
55. Taylor MR, Couto JR, Scallan CD, Ceriani RL & Peterson JA 1997 Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion. DNA Cell Biology 16 861-869.
56. Ugolini F, Charafe-Jauffret E, Bardou VJ, Geneix J, Adelaide J, Labat-Moleur F, Penault-Llorca F, Longy M, Jacquemier J, Birnbaum D et al. 2001 WNT pathway and mammary carcinogenesis: loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type. Oncogene 20 5810-5817.
57. Yoo KY, Tajima K, Kuroishi T, Hirose K, Yoshida M, Miura S & Murai H 1992 Independent protective effect of lactation against breast cancer: a case-control study in Japan. American Journal of Epidemiology 135 726-733.
58. Zaloznik AJ 1997 Breast cancer stage at diagnosis: Caucasians versus Hispanics. Breast Cancer Research and Treatment 42 121-124.
59. Zehentner BK, Dillon DC, Jiang Y, Xu J, Bennington A, Molesh DA, Zhang X, Reed SG, Persing D & Houghton RL 2002 Application of a multigene reverse transcription-PCR assay for detection of mammaglobin and complementary transcribed genes in breast cancer lymph nodes. Clinical Chemistry 48 1225-1231.