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Volumn 59, Issue 1, 2006, Pages 13-20

In vivo butyrylcholinesterase activity is not increased in Alzheimer's disease synapses

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PIPERIDINYL N BUTYRATE C 11; ACETYLCHOLINE; ACETYLCHOLINESTERASE; CARBON 11; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; DONEPEZIL; N METHYLPIPERIDIN 4 YL PROPIONATE C 11; PHYSOSTIGMINE; PIPERIDINE DERIVATIVE; RIVASTIGMINE; TRACER; UNCLASSIFIED DRUG;

EID: 29944441736     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.20672     Document Type: Article
Times cited : (63)

References (49)
  • 1
    • 0026608543 scopus 로고
    • Overlap between acetylcholinesteraserich and choline acetylttansferse- positive (cholinergic) axons in human cerebral cortex
    • Mesulam MM, Geula C. Overlap between acetylcholinesteraserich and choline acetylttansferse-positive (cholinergic) axons in human cerebral cortex. Brain Res 1992;577:112-120.
    • (1992) Brain Res , vol.577 , pp. 112-120
    • Mesulam, M.M.1    Geula, C.2
  • 2
    • 0027337833 scopus 로고
    • Neuroglial cholinesterases in the normal brain and in Alzheimer's disease: Relationship to plaques, tangles, and patterns of selective vulnerability
    • Wright CI, Geula C, Mesulam MM. Neuroglial cholinesterases in the normal brain and in Alzheimer's disease: relationship to plaques, tangles, and patterns of selective vulnerability. Ann Neurol 1993;34:373-384.
    • (1993) Ann Neurol , vol.34 , pp. 373-384
    • Wright, C.I.1    Geula, C.2    Mesulam, M.M.3
  • 3
    • 0027973241 scopus 로고
    • Butyrylcholinesterase activity differentiates the amyloid plaques of aging from those of dementia
    • Mesulam MM, Geula C. Butyrylcholinesterase activity differentiates the amyloid plaques of aging from those of dementia. Ann Neurol 1994;36:722-727.
    • (1994) Ann Neurol , vol.36 , pp. 722-727
    • Mesulam, M.M.1    Geula, C.2
  • 5
    • 0032741056 scopus 로고    scopus 로고
    • Selectivity of cholinesterase inhibition. Clinical implications for the treatment of Alzheimer's disease
    • Weinstock M. Selectivity of cholinesterase inhibition. Clinical implications for the treatment of Alzheimer's disease. CNS Drugs 1999;12:307-323.
    • (1999) CNS Drugs , vol.12 , pp. 307-323
    • Weinstock, M.1
  • 6
    • 0001885399 scopus 로고    scopus 로고
    • Cholinesterase inhibitors: From the Calabar bean to Alzheimer therapy
    • Giacobini E, ed. London: Martin Dunitz Ltd
    • Giacobini E. Cholinesterase inhibitors: from the Calabar bean to Alzheimer therapy. In: Giacobini E, ed. Cholinesterases and cholinesterase inhibits. London: Martin Dunitz Ltd, 2000:181-226.
    • (2000) Cholinesterases and Cholinesterase Inhibits , pp. 181-226
    • Giacobini, E.1
  • 7
    • 0036315026 scopus 로고    scopus 로고
    • Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: Correlation with cognitive benefit
    • Giacobini E, Spiegel R, Enz A, et al. Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit. J Neurol Transm 2002;109:1053-1065.
    • (2002) J Neurol Transm , vol.109 , pp. 1053-1065
    • Giacobini, E.1    Spiegel, R.2    Enz, A.3
  • 8
    • 0036363671 scopus 로고    scopus 로고
    • Advances in the treatment of Alzheimer's disease: Benefits of dual cholinesterase inhibition
    • Ballard CG. Advances in the treatment of Alzheimer's disease: benefits of dual cholinesterase inhibition. Eur Neurol 2002;47:64-70.
    • (2002) Eur Neurol , vol.47 , pp. 64-70
    • Ballard, C.G.1
  • 9
    • 0036183539 scopus 로고    scopus 로고
    • Widely spread butyrylcholinesterase can hydrolyze acetylcholine in the normal and Alzheimer brain
    • Mesulam MM, Guillozet A, Shaw P, Quinn B. Widely spread butyrylcholinesterase can hydrolyze acetylcholine in the normal and Alzheimer brain. Neurobiol Dis 2002;9:88-93.
    • (2002) Neurobiol Dis , vol.9 , pp. 88-93
    • Mesulam, M.M.1    Guillozet, A.2    Shaw, P.3    Quinn, B.4
  • 11
    • 4644320679 scopus 로고    scopus 로고
    • Butyrylcholinesterase, cholinergic neurotransmission and the pathology of Alzheimer's disease
    • Geula C, Darvesh S. Butyrylcholinesterase, cholinergic neurotransmission and the pathology of Alzheimer's disease. Drugs Today 2004;40:711-721.
    • (2004) Drugs Today , vol.40 , pp. 711-721
    • Geula, C.1    Darvesh, S.2
  • 12
    • 0011162190 scopus 로고
    • Selective loss of central cholinergic neurons in Alzheimer's disease
    • Davies P, Maloney AJR. Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet 1976;2:1403.
    • (1976) Lancet , vol.2 , pp. 1403
    • Davies, P.1    Maloney, A.J.R.2
  • 13
    • 0020686674 scopus 로고
    • Alzheimer's disease: A disorder of cortical cholinergic innervation
    • Coyle JT, Price DL, De Long MR. Alzheimer's disease: a disorder of cortical cholinergic innervation. Science 1983;219:1184-1190.
    • (1983) Science , vol.219 , pp. 1184-1190
    • Coyle, J.T.1    Price, D.L.2    De Long, M.R.3
  • 15
    • 0037183534 scopus 로고    scopus 로고
    • Sustained cholinesterase inhibition in AD patients receiving rivastigmine for 12 months
    • Darreh-Shori T, Almkvist O, Guan ZZ, et al. Sustained cholinesterase inhibition in AD patients receiving rivastigmine for 12 months. Neurology 2002;59:563-572.
    • (2002) Neurology , vol.59 , pp. 563-572
    • Darreh-Shori, T.1    Almkvist, O.2    Guan, Z.Z.3
  • 16
    • 1642441331 scopus 로고    scopus 로고
    • Pharmacology of selective acetylcholinesterase inhibitors: Implications for use in Alzheimer's disease
    • Liston DR, Nielsen JA, Villalobos A, et al. Pharmacology of selective acetylcholinesterase inhibitors: implications for use in Alzheimer's disease. Eur J Pharmacol 2004;486:9-17.
    • (2004) Eur J Pharmacol , vol.486 , pp. 9-17
    • Liston, D.R.1    Nielsen, J.A.2    Villalobos, A.3
  • 17
    • 2942514710 scopus 로고    scopus 로고
    • Cholinesterase inhibitors used in the treatment of Alzheimer's disease. The relationship between pharmacological effects and clinical efficacy
    • Wilkinson DG, Francis PT, Schwam E, Payne-Parrish J. Cholinesterase inhibitors used in the treatment of Alzheimer's disease. The relationship between pharmacological effects and clinical efficacy. Drugs Aging 2004;21:453-478.
    • (2004) Drugs Aging , vol.21 , pp. 453-478
    • Wilkinson, D.G.1    Francis, P.T.2    Schwam, E.3    Payne-Parrish, J.4
  • 18
    • 0035012753 scopus 로고    scopus 로고
    • Pharmacodynamic-tolerability relationships of cholinesterase inhibitors for Alzheimer's disease
    • Imbimbo BP. Pharmacodynamic-tolerability relationships of cholinesterase inhibitors for Alzheimer's disease. CNS Drugs 2001;15:375-390.
    • (2001) CNS Drugs , vol.15 , pp. 375-390
    • Imbimbo, B.P.1
  • 20
    • 0024417125 scopus 로고
    • Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease
    • Geula C, Mesulam MM. Special properties of cholinesterases in the cerebral cortex of Alzheimer's disease. Brain Res 1989;498:185-189.
    • (1989) Brain Res , vol.498 , pp. 185-189
    • Geula, C.1    Mesulam, M.M.2
  • 21
    • 0026794041 scopus 로고
    • Changes in acetylcholinesterase and buryrylcholinesterase in Alzheimer's disease resemble embryonic development: A study of molecular forms
    • Arendt T, Bruckner MK, Lange M, Bigl V. Changes in acetylcholinesterase and buryrylcholinesterase in Alzheimer's disease resemble embryonic development: a study of molecular forms. Neurochem Int 1992;21:381-396.
    • (1992) Neurochem Int , vol.21 , pp. 381-396
    • Arendt, T.1    Bruckner, M.K.2    Lange, M.3    Bigl, V.4
  • 22
    • 0028354734 scopus 로고
    • Ultrastructural localization of butyrylcholinesterase on neurofibrillary degeneration sites in the brains of aged and Alzheimer's disease patients
    • Gomez-Ramos P, Bouras C, Moran MA. Ultrastructural localization of butyrylcholinesterase on neurofibrillary degeneration sites in the brains of aged and Alzheimer's disease patients. Brain Res 1994;640:17-24.
    • (1994) Brain Res , vol.640 , pp. 17-24
    • Gomez-Ramos, P.1    Bouras, C.2    Moran, M.A.3
  • 23
    • 0029164755 scopus 로고
    • Cholinesterases and the pathology of Alzheimer disease
    • Geula C, Mesulam MM. Cholinesterases and the pathology of Alzheimer disease. Alzheimer Dis Assoc Disord 1995;9:23-28.
    • (1995) Alzheimer Dis Assoc Disord , vol.9 , pp. 23-28
    • Geula, C.1    Mesulam, M.M.2
  • 24
    • 0035129786 scopus 로고    scopus 로고
    • Radiolabeled cholinesterase substrates: In vitro methods for determining structure-activity relationships and identification of a positron emission tomography radiopharmaceutical for in vivo measurement of butyrylcholinesterase activity
    • Snyder SE, Gunupudi N, Sherman PS, et al. Radiolabeled cholinesterase substrates: in vitro methods for determining structure-activity relationships and identification of a positron emission tomography radiopharmaceutical for in vivo measurement of butyrylcholinesterase activity. J Cereb Blood Flow Metab 2001;21:132-143.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 132-143
    • Snyder, S.E.1    Gunupudi, N.2    Sherman, P.S.3
  • 25
    • 0027936170 scopus 로고
    • Design and evaluation of radioactive acetylcholine analogs of mapping brain acetylcholinesterase (AChE) in vivo
    • Irie T, Fukushi K, Akimoro Y, et al. Design and evaluation of radioactive acetylcholine analogs of mapping brain acetylcholinesterase (AChE) in vivo. Nucl Med Biol 1994;21:801-808.
    • (1994) Nucl Med Biol , vol.21 , pp. 801-808
    • Irie, T.1    Fukushi, K.2    Akimoro, Y.3
  • 27
    • 0032194844 scopus 로고    scopus 로고
    • 11C] PMP) for in vivo measurements of acetylcholinesterase activity
    • 11C] PMP) for in vivo measurements of acetylcholinesterase activity. Nucl Med Biol 1998;25:751-754.
    • (1998) Nucl Med Biol , vol.25 , pp. 751-754
    • Snyder, S.E.1    Tluczek, L.2    Jewet, D.M.3
  • 28
    • 0033541026 scopus 로고    scopus 로고
    • In vivo mapping of cerebral acetylcholinesterase activity in aging and Alzheimer's disease
    • Kuhl DE, Koeppe RA, Minoshima S, et al. In vivo mapping of cerebral acetylcholinesterase activity in aging and Alzheimer's disease. Neurology 1999;52:691-699.
    • (1999) Neurology , vol.52 , pp. 691-699
    • Kuhl, D.E.1    Koeppe, R.A.2    Minoshima, S.3
  • 29
    • 0033497793 scopus 로고    scopus 로고
    • 11C] methylpiperidin-4-yl propionate: Alternatives for analysis of an irreversible PET tracer for measurement of acetylcholinesterase activity in human brain
    • 11C] methylpiperidin-4-yl propionate: alternatives for analysis of an irreversible PET tracer for measurement of acetylcholinesterase activity in human brain. J Cereb Blood How Metab 1999;19:1150-1163.
    • (1999) J Cereb Blood How Metab , vol.19 , pp. 1150-1163
    • Koeppe, R.A.1    Frey, K.A.2    Snyder, S.E.3
  • 30
    • 0033844518 scopus 로고    scopus 로고
    • Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex
    • Kuhl DE, Minoshima S, Frey KA, et al. Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex. Ann Neurol 2000;48:391-395.
    • (2000) Ann Neurol , vol.48 , pp. 391-395
    • Kuhl, D.E.1    Minoshima, S.2    Frey, K.A.3
  • 31
    • 16644367327 scopus 로고    scopus 로고
    • 11C-methyl-4- piperidinyl n-butyrate in humans: An imaging agent for in vivo assessment of butyrylcholinesterase activity with PET
    • 11C-methyl-4-piperidinyl n-butyrate in humans: an imaging agent for in vivo assessment of butyrylcholinesterase activity with PET. J Nucl Med 2004;45:2032-2039.
    • (2004) J Nucl Med , vol.45 , pp. 2032-2039
    • Roivainen, A.1    Rinne, J.2    Virta, J.3
  • 32
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 33
    • 0020040238 scopus 로고
    • A new clinical scale for the staging of dementia
    • Hughes CP, Berg L, Danziger WL, et al. A new clinical scale for the staging of dementia. Br J Psychiatry 1982;140:566-572.
    • (1982) Br J Psychiatry , vol.140 , pp. 566-572
    • Hughes, C.P.1    Berg, L.2    Danziger, W.L.3
  • 34
    • 0016823810 scopus 로고
    • Mini Mental State: A practical method for grading the cognitive state of patients for the clinician
    • Folstein M, Folstein SE, McHugh PR. "Mini Mental State: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.1    Folstein, S.E.2    McHugh, P.R.3
  • 35
    • 0032194843 scopus 로고    scopus 로고
    • 11C] methylpiperidine esters as acetylcholinesterase substrates: An in vivo structure-activity study
    • 11C] methylpiperidine esters as acetylcholinesterase substrates: an in vivo structure-activity study. Nucl Med Biol 1998;25:755-760.
    • (1998) Nucl Med Biol , vol.25 , pp. 755-760
    • Kilbourn, M.R.1    Nguyen, T.B.2    Snyder, S.E.3    Sherman, P.4
  • 37
    • 0035727527 scopus 로고    scopus 로고
    • Selective inhibitors of butyrylcholinesterase: A valid alternative for therapy of Alzheimer's disease?
    • Giacobini E. Selective inhibitors of butyrylcholinesterase: a valid alternative for therapy of Alzheimer's disease? Drugs Aging 2001;18:891-898.
    • (2001) Drugs Aging , vol.18 , pp. 891-898
    • Giacobini, E.1
  • 38
    • 0038308812 scopus 로고    scopus 로고
    • Inhibition of human cholinesterases by drugs used to treat Alzheimer Disease
    • Darvesh S, Walsh R, Kumar R, et al. Inhibition of human cholinesterases by drugs used to treat Alzheimer Disease. Alzheimer Dis Assoc Disord 2003;17:117-126.
    • (2003) Alzheimer Dis Assoc Disord , vol.17 , pp. 117-126
    • Darvesh, S.1    Walsh, R.2    Kumar, R.3
  • 39
    • 0022475304 scopus 로고
    • Molecular forms of acetylcholinesterase and butyrylcholinesterase in the aged human central nervous system
    • Atack JR, Perry EK, Bonham JR, et al. Molecular forms of acetylcholinesterase and butyrylcholinesterase in the aged human central nervous system. J Neurochem 1986;47:263-277.
    • (1986) J Neurochem , vol.47 , pp. 263-277
    • Atack, J.R.1    Perry, E.K.2    Bonham, J.R.3
  • 40
    • 0037012468 scopus 로고    scopus 로고
    • Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine
    • Mesulam MM, Guillozet A, Shaw P, et al. Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine. Neuroscience 2002;110:627-639.
    • (2002) Neuroscience , vol.110 , pp. 627-639
    • Mesulam, M.M.1    Guillozet, A.2    Shaw, P.3
  • 42
    • 0034111218 scopus 로고    scopus 로고
    • The cholinergic deficit coincides with A-beta deposition at the earliest histopathologic stages of Alzheimer disease
    • Beach TG, Kuo YM, Spiegel K, et al. The cholinergic deficit coincides with A-beta deposition at the earliest histopathologic stages of Alzheimer disease. J Neuropathol Exp Neurol 2000;59:308-313.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 308-313
    • Beach, T.G.1    Kuo, Y.M.2    Spiegel, K.3
  • 43
    • 0036897310 scopus 로고    scopus 로고
    • Regional effects of donepezil and rivastigmine on cortical acetylcholinesterase activity in Alzheimer's disease
    • Kaasinen V, Nagren K, Jarvenpaa T, et al. Regional effects of donepezil and rivastigmine on cortical acetylcholinesterase activity in Alzheimer's disease. J Clin Psychopharmacol 2002;22:615-620.
    • (2002) J Clin Psychopharmacol , vol.22 , pp. 615-620
    • Kaasinen, V.1    Nagren, K.2    Jarvenpaa, T.3
  • 44
    • 2342440518 scopus 로고    scopus 로고
    • Acetylcholinesterase imaging: Its use in therapy evaluation and drug design
    • Shinotoh H, Fukushi K, Nagatsuka S, Irie T. Acetylcholinesterase imaging: its use in therapy evaluation and drug design. Curr Pharm Des 2004;10:1505-1517.
    • (2004) Curr Pharm Des , vol.10 , pp. 1505-1517
    • Shinotoh, H.1    Fukushi, K.2    Nagatsuka, S.3    Irie, T.4
  • 45
    • 20044380519 scopus 로고    scopus 로고
    • Degree of inhibition of cortical acetylcholinesterase activity and cognitive effects by donepezil treatment in Alzheimer's disease
    • Bohnen NI, Kaufer DI, Hendrickson R, et al. Degree of inhibition of cortical acetylcholinesterase activity and cognitive effects by donepezil treatment in Alzheimer's disease. J Neurol Neurosurg Psychiatry 2005;76:315-319.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 315-319
    • Bohnen, N.I.1    Kaufer, D.I.2    Hendrickson, R.3
  • 46
    • 0036560908 scopus 로고    scopus 로고
    • The origin of the molecular diversity and functional anchoring of cholinesterases
    • Massoulie J. The origin of the molecular diversity and functional anchoring of cholinesterases. Neurosignals 2002;11:130-143.
    • (2002) Neurosignals , vol.11 , pp. 130-143
    • Massoulie, J.1
  • 47
    • 0020545113 scopus 로고
    • Molecular forms of acetylcholinesterase in senile dementia of Alzheimer type: Selective loss of intermediate (10S) form
    • Atack JR, Perry EK, Bonham JR, et al. Molecular forms of acetylcholinesterase in senile dementia of Alzheimer type: selective loss of intermediate (10S) form. Neurosci Lett 1983;40:199-204.
    • (1983) Neurosci Lett , vol.40 , pp. 199-204
    • Atack, J.R.1    Perry, E.K.2    Bonham, J.R.3
  • 48
    • 0036336383 scopus 로고    scopus 로고
    • A multinational, randomised, 12-week, comparative study of donepezil and rivastigmine in patients with mild to moderate Alzheimer's disease
    • Wilkinson DG, Passmore AP, Bullick R, et al. A multinational, randomised, 12-week, comparative study of donepezil and rivastigmine in patients with mild to moderate Alzheimer's disease. Int J Clin Pract 2002;56:441-446.
    • (2002) Int J Clin Pract , vol.56 , pp. 441-446
    • Wilkinson, D.G.1    Passmore, A.P.2    Bullick, R.3
  • 49
    • 20244362525 scopus 로고    scopus 로고
    • Differential efficacy of treatment with acetylcholinesterase inhibitors in patients with mild and moderate Alzheimer's disease over a 6-month period
    • Lopez-Pousa S, Turon-Estrada A, Garre-Olmo J, et al. Differential efficacy of treatment with acetylcholinesterase inhibitors in patients with mild and moderate Alzheimer's disease over a 6-month period. Dement Geriatr Cogn Disord 2005;19:189-195.
    • (2005) Dement Geriatr Cogn Disord , vol.19 , pp. 189-195
    • Lopez-Pousa, S.1    Turon-Estrada, A.2    Garre-Olmo, J.3


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