-
1
-
-
0020072221
-
Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain
-
Whitehouse PJ, Price DL, Struble RG, et al. Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 1982; 215: 1237-9
-
(1982)
Science
, vol.215
, pp. 1237-1239
-
-
Whitehouse, P.J.1
Price, D.L.2
Struble, R.G.3
-
2
-
-
0026781603
-
Oxidative energy metabolism in Alzheimer brain. Studies in early-onset and late-onset cases
-
Hoyer S. Oxidative energy metabolism in Alzheimer brain. Studies in early-onset and late-onset cases. Mol Chem Neuropathol 1992; 16: 207-24
-
(1992)
Mol Chem Neuropathol
, vol.16
, pp. 207-224
-
-
Hoyer, S.1
-
3
-
-
0027959878
-
Brain glucose metabolism in Alzheimer's disease
-
Swedlow R, Marcus DL, Landman J, et al. Brain glucose metabolism in Alzheimer's disease. Am J Med Sci 1994; 308: 141-4
-
(1994)
Am J Med Sci
, vol.308
, pp. 141-144
-
-
Swedlow, R.1
Marcus, D.L.2
Landman, J.3
-
4
-
-
0028102129
-
Impaired brain microcirculation may trigger Alzeimer's disease
-
De la Torre JC. Impaired brain microcirculation may trigger Alzeimer's disease. Neurosci Biobehav Revs 1994; 18: 397-401
-
(1994)
Neurosci Biobehav Revs
, vol.18
, pp. 397-401
-
-
De la Torre, J.C.1
-
5
-
-
0031458235
-
Butyrylchofinesterase in the life cycle of amyloid plaques
-
Guillozet AL, Smiley JF, Mash DC, et al. Butyrylchofinesterase in the life cycle of amyloid plaques. Ann Neurol 1997; 42: 909-18
-
(1997)
Ann Neurol
, vol.42
, pp. 909-918
-
-
Guillozet, A.L.1
Smiley, J.F.2
Mash, D.C.3
-
6
-
-
0027429837
-
Brain selective inhibition of acetylcholinesterase: A novel approach to therapy for Alzheimer's disease
-
Enz A, Amstutz R, Boddeke H, et al. Brain selective inhibition of acetylcholinesterase: a novel approach to therapy for Alzheimer's disease. Prog Brain Res 1993; 98: 431-8
-
(1993)
Prog Brain Res
, vol.98
, pp. 431-438
-
-
Enz, A.1
Amstutz, R.2
Boddeke, H.3
-
7
-
-
0028709150
-
Pharmacological evaluation of phenyl-carbamates as CNS selective acetylcholinesterase inhibitors
-
Weinstock M, Razin M, Chorev M, et al. Pharmacological evaluation of phenyl-carbamates as CNS selective acetylcholinesterase inhibitors. J Neural Transm 1994; s43: 219-25
-
(1994)
J Neural Transm
, vol.S43
, pp. 219-225
-
-
Weinstock, M.1
Razin, M.2
Chorev, M.3
-
9
-
-
0029143531
-
Effectiveness and safety of velnacrine for the treatment of Alzheimer's disease
-
Antuono PG. Effectiveness and safety of velnacrine for the treatment of Alzheimer's disease. Arch Int Med 1995; 155: 1766-72
-
(1995)
Arch Int Med
, vol.155
, pp. 1766-1772
-
-
Antuono, P.G.1
-
10
-
-
0032921029
-
A 24-week randomized trial of controlled release physostigmine in patients with Alzheimer's disease
-
Thal LJ, Fergusen JM, Mintzer J, et al. A 24-week randomized trial of controlled release physostigmine in patients with Alzheimer's disease. Neurology 1999; 52: 1146-52
-
(1999)
Neurology
, vol.52
, pp. 1146-1152
-
-
Thal, L.J.1
Fergusen, J.M.2
Mintzer, J.3
-
11
-
-
0029860968
-
Relationship between pharmacodynamic activity and cognitive effects of eptastigmine in patients with Alzheimer's disease
-
Canal N, Imbimbo BP. Relationship between pharmacodynamic activity and cognitive effects of eptastigmine in patients with Alzheimer's disease. Clin Pharmacol Ther 1996; 60: 218-28
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 218-228
-
-
Canal, N.1
Imbimbo, B.P.2
-
12
-
-
0031902795
-
A randomized trial evaluating efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease
-
Corey-Bloom J, Anand R, Veach J, et al. A randomized trial evaluating efficacy and safety of ENA 713 (rivastigmine tartrate), a new acetylcholinesterase inhibitor, in patients with mild to moderately severe Alzheimer's disease. Int J Geriatric Psychopharmacol 1998; 1: 55-65
-
(1998)
Int J Geriatric Psychopharmacol
, vol.1
, pp. 55-65
-
-
Corey-Bloom, J.1
Anand, R.2
Veach, J.3
-
13
-
-
0031883716
-
A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
-
Rogers SL, Farlow MR, Doody RS, et al. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Neurology 1998; 50: 136-45
-
(1998)
Neurology
, vol.50
, pp. 136-145
-
-
Rogers, S.L.1
Farlow, M.R.2
Doody, R.S.3
-
14
-
-
0031842292
-
Metrifonate treatment of the cognitive deficits of Alzheimer's disease
-
Cummings JL, Cyrus PA, Bieber F, et al. Metrifonate treatment of the cognitive deficits of Alzheimer's disease. Neurology 1998; 50: 1214-21
-
(1998)
Neurology
, vol.50
, pp. 1214-1221
-
-
Cummings, J.L.1
Cyrus, P.A.2
Bieber, F.3
-
15
-
-
0002653806
-
Cryptic catalysis and cholinesterase function
-
Shafferman A, Velan B, editors, New York (NY): Plenum Press
-
Quin DM, Selwood T, Pryor AN, et al. Cryptic catalysis and cholinesterase function. In: Shafferman A, Velan B, editors. Multidisciplinary approaches to cholinesterase function. New York (NY): Plenum Press, 1992: 141-8
-
(1992)
Multidisciplinary Approaches to Cholinesterase Function
, pp. 141-148
-
-
Quin, D.M.1
Selwood, T.2
Pryor, A.N.3
-
16
-
-
0026447003
-
Secreted acetylcholinesterase: Non-classical aspects of a classical enzyme
-
Appleyard ME. Secreted acetylcholinesterase: non-classical aspects of a classical enzyme. Trends Neurosci 1992; 15 (12): 485-90
-
(1992)
Trends Neurosci
, vol.15
, Issue.12
, pp. 485-490
-
-
Appleyard, M.E.1
-
17
-
-
0025348704
-
Non-cholinergic actions of acetylcholinesterases: Proteases regulating cell growth and development
-
Small DH. Non-cholinergic actions of acetylcholinesterases: proteases regulating cell growth and development. Trends Biochem Sci 1990; 15 (6): 213-6
-
(1990)
Trends Biochem Sci
, vol.15
, Issue.6
, pp. 213-216
-
-
Small, D.H.1
-
18
-
-
0026698976
-
Mapping the human acetycholinesterase gene to chromosome 7q22 by fluorescent in situ hybridization coupled with selective PCR amplification from a somatic hybrid cell panel and chromosome-sorted DNA libraries
-
Ehrlich G, Viegas-Pequignot E, Ginzberg D, et al. Mapping the human acetycholinesterase gene to chromosome 7q22 by fluorescent in situ hybridization coupled with selective PCR amplification from a somatic hybrid cell panel and chromosome-sorted DNA libraries. Genomics 1992; 13: 1192-7
-
(1992)
Genomics
, vol.13
, pp. 1192-1197
-
-
Ehrlich, G.1
Viegas-Pequignot, E.2
Ginzberg, D.3
-
19
-
-
0027318577
-
Molecular and cellular biology of cholinesterases
-
Massoulic J, Pezzementi L, Bon S, et al. Molecular and cellular biology of cholinesterases. Progr Neurobiol 1993; 41: 31-91
-
(1993)
Progr Neurobiol
, vol.41
, pp. 31-91
-
-
Massoulic, J.1
Pezzementi, L.2
Bon, S.3
-
20
-
-
0022475304
-
Molecular forms of acetylcholinesterase and butyrylcholinesterase in the aged human central nervous system
-
Atack JR, Perry EK, Bonham JR, et al. Molecular forms of acetylcholinesterase and butyrylcholinesterase in the aged human central nervous system. J Neurochem 1986; 47 (1); 263-77
-
(1986)
J Neurochem
, vol.47
, Issue.1
, pp. 263-277
-
-
Atack, J.R.1
Perry, E.K.2
Bonham, J.R.3
-
21
-
-
0025213932
-
Molecular forms of acetylcholinesterase in subcortical areas of normal and Alzheimer disease brain
-
Siek GC, Katz LS, Fishman EB, et al. Molecular forms of acetylcholinesterase in subcortical areas of normal and Alzheimer disease brain. Biol Psychiatry 1990; 27: 573-80
-
(1990)
Biol Psychiatry
, vol.27
, pp. 573-580
-
-
Siek, G.C.1
Katz, L.S.2
Fishman, E.B.3
-
22
-
-
0025778840
-
Atomic structure of acetylcholinesterase from Torpedo californica: A prototypic acetylcholine-binding protein
-
Sussman JL, Harel M, Frolow F, et al. Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein. Science 1991; 253: 872-9
-
(1991)
Science
, vol.253
, pp. 872-879
-
-
Sussman, J.L.1
Harel, M.2
Frolow, F.3
-
23
-
-
0013945471
-
Responses of acetylcholinesterase from Torpedo marmorata to salts and curarizing drugs
-
Changeux J-P. Responses of acetylcholinesterase from Torpedo marmorata to salts and curarizing drugs. Mol Pharmacol 1966; 2: 369-92
-
(1966)
Mol Pharmacol
, vol.2
, pp. 369-392
-
-
Changeux, J.-P.1
-
25
-
-
0026454813
-
Conversion of acetylcholinesterase to butyryl-cholinesterase. Modeling and mutagenesis
-
Harel M, Sussman JL, Krejei F, et al. Conversion of acetylcholinesterase to butyryl-cholinesterase. Modeling and mutagenesis. Proc Natl Acad Sci U S A 1992; 89 (22): 10827-31
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, Issue.22
, pp. 10827-10831
-
-
Harel, M.1
Sussman, J.L.2
Krejei, F.3
-
26
-
-
0033043305
-
A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066
-
Snape MF, Misra A, Murray TK, et al. A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066. Neuropharmacology 1999; 38: 181-93
-
(1999)
Neuropharmacology
, vol.38
, pp. 181-193
-
-
Snape, M.F.1
Misra, A.2
Murray, T.K.3
-
27
-
-
0030763602
-
From molecular structure to Alzheimer therapy
-
Giacobini E. From molecular structure to Alzheimer therapy. Jpn J Pharmacol 1997; 74: 225-41
-
(1997)
Jpn J Pharmacol
, vol.74
, pp. 225-241
-
-
Giacobini, E.1
-
29
-
-
0032458505
-
Three-dimensional structure of a complex of E2020 with acetylcholinesterase from Torpedo California
-
Kryger G, Silman I, Sussman JL. Three-dimensional structure of a complex of E2020 with acetylcholinesterase from Torpedo California. J Physiol Paris 1998; 92: 191-4
-
(1998)
J Physiol Paris
, vol.92
, pp. 191-194
-
-
Kryger, G.1
Silman, I.2
Sussman, J.L.3
-
30
-
-
0032928788
-
Clinical profile of donepezil in the treatment of Alzheimer's disease
-
Doody RS, Clinical profile of donepezil in the treatment of Alzheimer's disease. Gerontology 1999; 45: 23-32
-
(1999)
Gerontology
, vol.45
, pp. 23-32
-
-
Doody, R.S.1
-
31
-
-
0028301112
-
Efficacy and safety of high-dose tacrine: A 30-week evaluation
-
Knapp MJ, Gracon SI, Davis CS, et al. Efficacy and safety of high-dose tacrine: a 30-week evaluation. Alz Dis Assoc Disord 1994; 8: s22-s31
-
(1994)
Alz Dis Assoc Disord
, vol.8
-
-
Knapp, M.J.1
Gracon, S.I.2
Davis, C.S.3
-
32
-
-
0030612202
-
Possible role of the cholinergic system and disease models
-
Weinstock M. Possible role of the cholinergic system and disease models. J Neural Transm 1997; Suppl. 49: 93-102
-
(1997)
J Neural Transm Suppl.
, vol.49
, pp. 93-102
-
-
Weinstock, M.1
-
33
-
-
84945058027
-
Inhibition of acetylcholinesterase activity in human brain tissue and crythrocytes by galanthamine, physostigmine and tacrine
-
Thomsen T, Kaden B, Fischer JP, et al. Inhibition of acetylcholinesterase activity in human brain tissue and crythrocytes by galanthamine, physostigmine and tacrine. Eur J Clin Chem Clin Biochem 1991; 29: 487-92
-
(1991)
Eur J Clin Chem Clin Biochem
, vol.29
, pp. 487-492
-
-
Thomsen, T.1
Kaden, B.2
Fischer, J.P.3
-
34
-
-
0031842293
-
Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease
-
Morris JC, Cyrus PA, Orazem J, et al. Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease. Neurology 1998; 50: 1222-30
-
(1998)
Neurology
, vol.50
, pp. 1222-1230
-
-
Morris, J.C.1
Cyrus, P.A.2
Orazem, J.3
-
35
-
-
0031700960
-
Mechanism of action and metabolism of acetylcholinesterase inhibitors: Implications for treatment
-
Farlow MR, Hake AM. Mechanism of action and metabolism of acetylcholinesterase inhibitors: implications for treatment. Int J Ger Psychopharmacol 1998; 1 Suppl. 1: s2-s6
-
(1998)
Int J Ger Psychopharmacol
, vol.1
, Issue.SUPPL. 1
-
-
Farlow, M.R.1
Hake, A.M.2
-
36
-
-
0001945744
-
Cholinesterase inhibitors: An overview of their mechanism of action
-
Becker R, Giacobini F, editors. Boston (MA); Birkhauser
-
Enz A, Florsheim P. Cholinesterase inhibitors: an overview of their mechanism of action. In: Becker R, Giacobini F, editors, Alzheimer's disease. From molecular biology to therapy. Boston (MA); Birkhauser, 1996: 211-5
-
(1996)
Alzheimer's Disease. From Molecular Biology to Therapy
, pp. 211-215
-
-
Enz, A.1
Florsheim, P.2
-
37
-
-
0031897295
-
Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease
-
Cutler NR, Polinsky RJ, Sramek JJ, et al. Dose-dependent CSF acetylcholinesterase inhibition by SDZ ENA 713 in Alzheimer's disease. Acta Neurol Scand 1998; 97: 244-50
-
(1998)
Acta Neurol Scand
, vol.97
, pp. 244-250
-
-
Cutler, N.R.1
Polinsky, R.J.2
Sramek, J.J.3
-
38
-
-
0028890937
-
A multiple-dose safety trial of eptastigmine in Alzheimer's disease, with pharmacodynamic observations of red blood cell cholinesterase
-
Sramek JJ, Block GA, Reines SA, et al. A multiple-dose safety trial of eptastigmine in Alzheimer's disease, with pharmacodynamic observations of red blood cell cholinesterase. Life Sci 1995; 56 (5): 319-26
-
(1995)
Life Sci
, vol.56
, Issue.5
, pp. 319-326
-
-
Sramek, J.J.1
Block, G.A.2
Reines, S.A.3
-
39
-
-
0026645616
-
Preferential inhibition of acetylcholinesterase forms in rat brain
-
Organe N, Giacobini E, Messamore E, Preferential inhibition of acetylcholinesterase forms in rat brain. Neurochem Res 1992; 17: 485-95
-
(1992)
Neurochem Res
, vol.17
, pp. 485-495
-
-
Organe, N.1
Giacobini, E.2
Messamore, E.3
-
40
-
-
0031910978
-
Donepezil use in Alzheimer disease
-
Burner EL, Gray SL. Donepezil use in Alzheimer disease. Ann Pharmacother 1998; 32 (1): 70-7
-
(1998)
Ann Pharmacother
, vol.32
, Issue.1
, pp. 70-77
-
-
Burner, E.L.1
Gray, S.L.2
-
42
-
-
0022899577
-
Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type
-
Summers WK, Majovski LV, Marsh CM, et al. Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type. New Engl J Med 1986; 315: 1241-5
-
(1986)
New Engl J Med
, vol.315
, pp. 1241-1245
-
-
Summers, W.K.1
Majovski, L.V.2
Marsh, C.M.3
-
43
-
-
0029898842
-
Distribution of tacrine and metabolites in rat brain and plasma after single and multiple-dose regimens: Evidence for the accumulation of tacrine in brain tissue
-
McNally WP, Pool WF, Sinz MW, et al. Distribution of tacrine and metabolites in rat brain and plasma after single and multiple-dose regimens: evidence for the accumulation of tacrine in brain tissue. Drug Metab Dispos 1996; 24: 628-33
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 628-633
-
-
McNally, W.P.1
Pool, W.F.2
Sinz, M.W.3
-
44
-
-
84910822747
-
Selective inhibition of acetylcholinesterase and acetylcholine turnover in the cortex and hippocampus
-
Cohen S, Sokolovsky M, editors. Tel Aviv: Freund Publishing House
-
Weinstock M, Kay G, Razin M, et al. Selective inhibition of acetylcholinesterase and acetylcholine turnover in the cortex and hippocampus. In: Cohen S, Sokolovsky M, editors. Muscarinic cholinergic mechanisms. Tel Aviv: Freund Publishing House, 1987
-
(1987)
Muscarinic Cholinergic Mechanisms
-
-
Weinstock, M.1
Kay, G.2
Razin, M.3
-
45
-
-
0031798082
-
Dementia with Lewy bodies: Response of delirium-like features to donepezil
-
Kaufer DI, Catt KE, Lopez OL, et al. Dementia with Lewy bodies: response of delirium-like features to donepezil. Neurology 1998; 51 (5): 1512
-
(1998)
Neurology
, vol.51
, Issue.5
, pp. 1512
-
-
Kaufer, D.I.1
Catt, K.E.2
Lopez, O.L.3
-
47
-
-
0033541027
-
Efficacy and safety of eptastigmine for the treatment of patients with Alzheimer's disease
-
Imbimbo BP, Martelli P, Troetel WM, et al. Efficacy and safety of eptastigmine for the treatment of patients with Alzheimer's disease. Neurology 1999; 52: 700-8
-
(1999)
Neurology
, vol.52
, pp. 700-708
-
-
Imbimbo, B.P.1
Martelli, P.2
Troetel, W.M.3
-
48
-
-
0029924782
-
Double-blind placebo-controlled study of velnacrine in Alzheimer's disease
-
Zemlan FP, Keys M, Richter RW, et al. Double-blind placebo-controlled study of velnacrine in Alzheimer's disease. Life Sci 1996; 58: 1823-32
-
(1996)
Life Sci
, vol.58
, pp. 1823-1832
-
-
Zemlan, F.P.1
Keys, M.2
Richter, R.W.3
-
49
-
-
0023049733
-
Anticholinesterase activity of a new carbamate, heptylphysotigmine, in view of its use in patients with Alzheimer-type dementia
-
Brufani M, Marta M, Pomponi M. Anticholinesterase activity of a new carbamate, heptylphysotigmine, in view of its use in patients with Alzheimer-type dementia. Eur J Biochem 1986; 157: 115-20
-
(1986)
Eur J Biochem
, vol.157
, pp. 115-120
-
-
Brufani, M.1
Marta, M.2
Pomponi, M.3
-
50
-
-
0029778789
-
Clinical development of Exelon™(ENA-713): The ADENA programme
-
Anand R, Gharabawi G. Clinical development of Exelon™(ENA-713): the ADENA programme. J Drug Dev Clin Pract 1996; 8: 9-14
-
(1996)
J Drug Dev Clin Pract
, vol.8
, pp. 9-14
-
-
Anand, R.1
Gharabawi, G.2
-
51
-
-
0026731189
-
Occurrence of acetylcholinesterase activity closely associated with amyloid β/A4 protein is not correlated with acetylcholinesterase-positive fiber density in amygdala of Alzheimer's disease
-
Nakamura S, Takemura M, Suenaga T, et al. Occurrence of acetylcholinesterase activity closely associated with amyloid β/A4 protein is not correlated with acetylcholinesterase-positive fiber density in amygdala of Alzheimer's disease. Acta Neuropathol 1992; 84: 425-32
-
(1992)
Acta Neuropathol
, vol.84
, pp. 425-432
-
-
Nakamura, S.1
Takemura, M.2
Suenaga, T.3
-
52
-
-
0029863697
-
Acetylcholinesterase accelerates assembly of amyliod-beta-peptides into Alzneimer's fibrils; Possible role of the peripheral site of the enzyme
-
Inestrosa NC, Alvarez A, Perez CA, et al. Acetylcholinesterase accelerates assembly of amyliod-beta-peptides into Alzneimer's fibrils; possible role of the peripheral site of the enzyme. Neuron 1996; 16: 881-91
-
(1996)
Neuron
, vol.16
, pp. 881-891
-
-
Inestrosa, N.C.1
Alvarez, A.2
Perez, C.A.3
-
53
-
-
0023589282
-
Anatomy of cholinesterase inhibition in Alzheimer's disease: Effect of physostigmine and tetrahydroamnoacridine on plaques and tangles
-
Mesulam M-M, Geula C, Moran MA. Anatomy of cholinesterase inhibition in Alzheimer's disease: effect of physostigmine and tetrahydroamnoacridine on plaques and tangles. Ann Neurol 1987; 22: 683-91
-
(1987)
Ann Neurol
, vol.22
, pp. 683-691
-
-
Mesulam, M.-M.1
Geula, C.2
Moran, M.A.3
-
54
-
-
0030581107
-
Amyloidogenic processing of Alzheimer's amyloid precursor protein in vitro and its modulation by metal ions and tacrine
-
Chong YH, Su Y-H. Amyloidogenic processing of Alzheimer's amyloid precursor protein in vitro and its modulation by metal ions and tacrine. Life Sci 1996; 59: 545-57
-
(1996)
Life Sci
, vol.59
, pp. 545-557
-
-
Chong, Y.H.1
Su, Y.-H.2
-
55
-
-
0032507596
-
Tacrine and donepezil attenuate the neurotoxic effect of A beta (25-35) in rat PC 12 cells
-
Svensson AL, Nordberg A. Tacrine and donepezil attenuate the neurotoxic effect of A beta (25-35) in rat PC 12 cells. Neuroreport 1998; 9: 1519-22
-
(1998)
Neuroreport
, vol.9
, pp. 1519-1522
-
-
Svensson, A.L.1
Nordberg, A.2
-
56
-
-
0000134682
-
Cholinesterase inhibitors do more than inhibit cholinesterase
-
Becker R, Giacobini H, editors. Boston (MA): Birkhauser
-
Giacobini E. Cholinesterase inhibitors do more than inhibit cholinesterase. In: Becker R, Giacobini H, editors. Alzheimer's disease. From molecular biology to therapy. Boston (MA): Birkhauser, 1996: 187-204
-
(1996)
Alzheimer's Disease. From Molecular Biology to Therapy
, pp. 187-204
-
-
Giacobini, E.1
-
57
-
-
0026646328
-
In vivo neurotoxicity of β-amyloid β(1-40) and the β(25-35) fragment
-
Kowall NW, McKee AC, Yankner BA, et al. In vivo neurotoxicity of β-amyloid β(1-40) and the β(25-35) fragment. Neurobiol Aging 1992; 13: 537-42
-
(1992)
Neurobiol Aging
, vol.13
, pp. 537-542
-
-
Kowall, N.W.1
McKee, A.C.2
Yankner, B.A.3
-
58
-
-
0030048606
-
Amnesia induced in mice by centrally-administered β-amyloid peptides involves cholinergic dysfunction
-
Maurice T, Lockhart BP, Privat A. Amnesia induced in mice by centrally-administered β-amyloid peptides involves cholinergic dysfunction. Brain Res 1996; 706: 181-93
-
(1996)
Brain Res
, vol.706
, pp. 181-193
-
-
Maurice, T.1
Lockhart, B.P.2
Privat, A.3
-
59
-
-
0029865605
-
11C] methionine accumulation in probable Alzheimer's disease using positron emission tomography
-
11C] methionine accumulation in probable Alzheimer's disease using positron emission tomography. J Cereb Blood Flow Metab 1996; 16: 309-408
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 309-408
-
-
Salmon, F.1
Gregoire, M.C.2
Delfiore, C.3
-
60
-
-
0028241915
-
Decreased concentraitions of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease
-
Simpson IA, Koteswara RC, Davies-Hill T, et al. Decreased concentraitions of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease. Ann Neurol 1994; 35: 546-51
-
(1994)
Ann Neurol
, vol.35
, pp. 546-551
-
-
Simpson, I.A.1
Koteswara, R.C.2
Davies-Hill, T.3
-
61
-
-
0027933949
-
Immunolabelling of hippocampal microvessel glucose transporter protein is reduced in Alzheimer's disease
-
Horwood N, Davies DC. Immunolabelling of hippocampal microvessel glucose transporter protein is reduced in Alzheimer's disease. Virchows Archiv 1994; 425: 69-72
-
(1994)
Virchows Archiv
, vol.425
, pp. 69-72
-
-
Horwood, N.1
Davies, D.C.2
-
62
-
-
0024780235
-
Abnormalities of the glucose transporter at the blood-brain barrier and in brain in Alzheimer's disease
-
Kalaria RN, Hank SI. Abnormalities of the glucose transporter at the blood-brain barrier and in brain in Alzheimer's disease. Prog Clin Bio Res 1989; 317: 415-21
-
(1989)
Prog Clin Bio Res
, vol.317
, pp. 415-421
-
-
Kalaria, R.N.1
Hank, S.I.2
-
63
-
-
0024510221
-
Time course of effects of unilateral lesions of the nucleus basalis of Meynert on glucose utilisation by the cerebral cortex
-
Kiyosawa M, Baron J-C, Hamel E, et al. Time course of effects of unilateral lesions of the nucleus basalis of Meynert on glucose utilisation by the cerebral cortex. Brain 1989; 112: 435-55
-
(1989)
Brain
, vol.112
, pp. 435-455
-
-
Kiyosawa, M.1
Baron, J.-C.2
Hamel, E.3
-
64
-
-
0026687131
-
Regulation of regional cerebral blood flow by cholinergic fibers originating in the basal forebrain
-
Sato A, Sato Y. Regulation of regional cerebral blood flow by cholinergic fibers originating in the basal forebrain. Neurosci Res 1992; 14: 242-74
-
(1992)
Neurosci Res
, vol.14
, pp. 242-274
-
-
Sato, A.1
Sato, Y.2
-
65
-
-
0025775107
-
Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex
-
Abe K, Tanzi RE, Kogure K, Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex. Neurosci Lett 1991; 125: 172-4
-
(1991)
Neurosci Lett
, vol.125
, pp. 172-174
-
-
Abe, K.1
Tanzi, R.E.2
Kogure, K.3
-
66
-
-
0022616654
-
Alzheimer's disease
-
Katzman R. Alzheimer's disease. N Engl J Med 1986; 314: 964-73
-
(1986)
N Engl J Med
, vol.314
, pp. 964-973
-
-
Katzman, R.1
-
67
-
-
0024244538
-
Physostigmine enhances blood flow-metabolism ratio in neocortex
-
Seremin OU, Allen K, Torres C, et al. Physostigmine enhances blood flow-metabolism ratio in neocortex. Neuropsychopharmacol 1988; 1: 297-303
-
(1988)
Neuropsychopharmacol
, vol.1
, pp. 297-303
-
-
Seremin, O.U.1
Allen, K.2
Torres, C.3
-
68
-
-
0027159190
-
Prolonged effects of cholinesterase inhibition with eptastigmine on the cerebral blood flow-metabolism ratio of normal rats
-
Seremin OU, Seremin AME, Heuser D, et al. Prolonged effects of cholinesterase inhibition with eptastigmine on the cerebral blood flow-metabolism ratio of normal rats. J Cereb Blood Flow Metab 1993; 13: 702-11
-
(1993)
J Cereb Blood Flow Metab
, vol.13
, pp. 702-711
-
-
Seremin, O.U.1
Seremin, A.M.E.2
Heuser, D.3
-
69
-
-
0030896126
-
Tacrine overcomnensates for the decreased blood flow induced by basal forebrain lesion in the rat
-
Peruzzi P, Borredon J, Seylaz J, et al. Tacrine overcomnensates for the decreased blood flow induced by basal forebrain lesion in the rat. Neuroreport 1996; 8: 103-8
-
(1996)
Neuroreport
, vol.8
, pp. 103-108
-
-
Peruzzi, P.1
Borredon, J.2
Seylaz, J.3
-
70
-
-
0030957933
-
Functional activation of cerebral blood flow abolished by scopolamine is reversed by cognitive enhancers associated with cholinesterase inhibition: A positron emission tomography study in unanesthetized monkeys
-
Tsukada H, Kakiuchi T, Ando I, et al. Functional activation of cerebral blood flow abolished by scopolamine is reversed by cognitive enhancers associated with cholinesterase inhibition: a positron emission tomography study in unanesthetized monkeys. J Pharmacol Exptl Ther 1997; 281: 1408-14
-
(1997)
J Pharmacol Exptl Ther
, vol.281
, pp. 1408-1414
-
-
Tsukada, H.1
Kakiuchi, T.2
Ando, I.3
-
71
-
-
0026687684
-
Effects of a single dose of me aceylcholinesterase inhibitor velnacrine on recognition memory and regional blood flow in Alzheimer's dis case
-
Ebmeier KB, Hunter R, Curran SM, et al. Effects of a single dose of me aceylcholinesterase inhibitor velnacrine on recognition memory and regional blood flow in Alzheimer's dis case. Psychopharmacol 1992; 108: 103-9
-
(1992)
Psychopharmacol
, vol.108
, pp. 103-109
-
-
Ebmeier, K.B.1
Hunter, R.2
Curran, S.M.3
-
72
-
-
0027512824
-
Oral tetrahydroaminoacridine treatment of Alzheimer's disease evaluated clinically and by regional cerebral blood flow
-
Minthon L, Gustafson L, Dalfelt G, et al. Oral tetrahydroaminoacridine treatment of Alzheimer's disease evaluated clinically and by regional cerebral blood flow. Dementia 1993; 4: 32-42
-
(1993)
Dementia
, vol.4
, pp. 32-42
-
-
Minthon, L.1
Gustafson, L.2
Dalfelt, G.3
-
73
-
-
0030697379
-
Tacrine treatment in Alzheimer's disease enhances cerebral blood flow and mental status and decreases caregiver suffering
-
Harkins SW, Taylor JR, Mattay V, et al. Tacrine treatment in Alzheimer's disease enhances cerebral blood flow and mental status and decreases caregiver suffering. Ann N Y Acad Sci 1997; 826: 472-4
-
(1997)
Ann N Y Acad Sci
, vol.826
, pp. 472-474
-
-
Harkins, S.W.1
Taylor, J.R.2
Mattay, V.3
-
74
-
-
0029053984
-
Post-ischemic administration of the acetyl-cholinesterase inhibitor ENA-713 prevents delayed neuronal death in the gerbil hippocampus
-
Tanaka K, Mizukawa K, Ogawa N, et al. Post-ischemic administration of the acetyl-cholinesterase inhibitor ENA-713 prevents delayed neuronal death in the gerbil hippocampus. Neurochem Res 1995; 20: 663-7
-
(1995)
Neurochem Res
, vol.20
, pp. 663-667
-
-
Tanaka, K.1
Mizukawa, K.2
Ogawa, N.3
-
75
-
-
0028123347
-
Aceylcholinesterase inhibitor ENA-713 protects against ischemia-induced decrease in pre- and postsynaptic cholinergic indices in the gerbil brain following transient ischemia
-
Tanaka K, Ogawa N, Mizukawa K, et al, Aceylcholinesterase inhibitor ENA-713 protects against ischemia-induced decrease in pre- and postsynaptic cholinergic indices in the gerbil brain following transient ischemia. Neurochem Res 1994; 19: 117-22
-
(1994)
Neurochem Res
, vol.19
, pp. 117-122
-
-
Tanaka, K.1
Ogawa, N.2
Mizukawa, K.3
-
76
-
-
0029145847
-
Inhibition of acetylcho linesterase modulates the autoregulation of cerebral blood flow and attenuates ischemic brain metabolism in hypertensive rats
-
Sadoshima S, Ibayashi S, Fujii K, et al. Inhibition of acetylcho linesterase modulates the autoregulation of cerebral blood flow and attenuates ischemic brain metabolism in hypertensive rats. J Cereb Blood Flow Metab 1995; 15: 845-51
-
(1995)
J Cereb Blood Flow Metab
, vol.15
, pp. 845-851
-
-
Sadoshima, S.1
Ibayashi, S.2
Fujii, K.3
-
77
-
-
0027278450
-
Molecular pathology of head trauma: Altered βAPP metabolism and the aetiology of Alzheimer's disease
-
Gentleman SM, Graham DI, Robert G.W. Molecular pathology of head trauma: Altered βAPP metabolism and the aetiology of Alzheimer's disease. Prog Brain Res 1993; 96: 237-46
-
(1993)
Prog Brain Res
, vol.96
, pp. 237-246
-
-
Gentleman, S.M.1
Graham, D.I.2
Robert, G.W.3
-
78
-
-
0032536412
-
Cerebro-protective effects of ENA713, a novel acetylcholinesterase inhibitor, in closed head injury in the rat
-
Then Y, Shohami E, Bass R, et al. Cerebro-protective effects of ENA713, a novel acetylcholinesterase inhibitor, in closed head injury in the rat. Brain Res 1998; 784: 18-24
-
(1998)
Brain Res
, vol.784
, pp. 18-24
-
-
Then, Y.1
Shohami, E.2
Bass, R.3
-
79
-
-
85016855413
-
Rivastigmine, a brain-selective acetyl-cholinesterase inhibitor, ameliorates cognitive and motor deficits induced by closed-head injury in the mouse
-
Chen Y, Shohami E, Constanini S, et al. Rivastigmine, a brain-selective acetyl-cholinesterase inhibitor, ameliorates cognitive and motor deficits induced by closed-head injury in the mouse. J Neurotrauma 1998: 15; 231-7
-
(1998)
J Neurotrauma
, vol.15
, pp. 231-237
-
-
Chen, Y.1
Shohami, E.2
Constanini, S.3
-
80
-
-
0028786448
-
The role of excitatory amino acids in severe brain trauma: Opportunities for therapy; A review
-
Zauner A, Bullock R. The role of excitatory amino acids in severe brain trauma: opportunities for therapy: a review, J Neurotrauma 1995; 12: 547-54
-
(1995)
J Neurotrauma
, vol.12
, pp. 547-554
-
-
Zauner, A.1
Bullock, R.2
-
81
-
-
0031594161
-
Donepezil medicated memory improvement in traumatic brain injury during post acute rehabilitation
-
Taverni JP, Seliger G, Lichtman SW. Donepezil medicated memory improvement in traumatic brain injury during post acute rehabilitation. Brain Inj 1998; 12: 77-80
-
(1998)
Brain Inj
, vol.12
, pp. 77-80
-
-
Taverni, J.P.1
Seliger, G.2
Lichtman, S.W.3
-
82
-
-
0028805907
-
Metabolic response to tacrine (THA) and physostigmine in the aged rat brain
-
Bassant MH, Jazat-Poindessous F, Lamour Y. Metabolic response to tacrine (THA) and physostigmine in the aged rat brain. J Cerch Blood Flow Metab 1995; 15: 1093-102
-
(1995)
J Cerch Blood Flow Metab
, vol.15
, pp. 1093-1102
-
-
Bassant, M.H.1
Jazat-Poindessous, F.2
Lamour, Y.3
-
83
-
-
0029744529
-
Effect of metri fonate, a cholinesterase inhibitor, on local cerebral glucose utilization in young and aged rats
-
Bassant MH, Jazat-Poindessous F, Lamour Y, Effect of metri fonate, a cholinesterase inhibitor, on local cerebral glucose utilization in young and aged rats. J Cereb Blood Flow Metab 1996; 16: 1014-25
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 1014-1025
-
-
Bassant, M.H.1
Jazat-Poindessous, F.2
Lamour, Y.3
-
84
-
-
0025797284
-
Tetrahydroam inoacridine alleviates medial septal lesion-induced and age-related spatial reference but not working memory deficits
-
Rickkenen Jr P, Aaltonen M, Sirvio J, et al. Tetrahydroam inoacridine alleviates medial septal lesion-induced and age-related spatial reference but not working memory deficits. Physiol Behav 1991; 49: 1147-52
-
(1991)
Physiol Behav
, vol.49
, pp. 1147-1152
-
-
Rickkenen P., Jr.1
Aaltonen, M.2
Sirvio, J.3
-
85
-
-
0030575536
-
Metrifonate improves spatial navigation and avoidance behavior in scopolamine-treated, medial septum-lesioned and aged rats
-
Rickkenen Jr P. Schmidt B, Stefanski R, et al. Metrifonate improves spatial navigation and avoidance behavior in scopolamine-treated, medial septum-lesioned and aged rats. Eur J Pharmacol 1996; 309: 121-30
-
(1996)
Eur J Pharmacol
, vol.309
, pp. 121-130
-
-
Rickkenen P., Jr.1
Schmidt, B.2
Stefanski, R.3
-
86
-
-
0028598190
-
Intraccrebroventrieular injection of streptozotocin induces discrete local changes in cerebral glucose utilisation in rats
-
Duelli R, Schrock G, Kuschinsky W, et al. Intraccrebroventrieular injection of streptozotocin induces discrete local changes in cerebral glucose utilisation in rats. Int J Dev Neurosci 1994; 12: 737-43
-
(1994)
Int J Dev Neurosci
, vol.12
, pp. 737-743
-
-
Duelli, R.1
Schrock, G.2
Kuschinsky, W.3
-
87
-
-
0009467209
-
Increase in cerebral blood flow and glucose utilization in beneficial effect of a cholinesterase inhibitor ENA713, in Alzheimer's disease
-
Fisher A, Hanin I, Yoshida M, editors. New York and London: Plenum Press. Adv Behav Biol: 49
-
Weinstock M, Increase in cerebral blood flow and glucose utilization in beneficial effect of a cholinesterase inhibitor ENA713, in Alzheimer's disease, In: Fisher A, Hanin I, Yoshida M, editors. Progress in Alzheimer's and Parkinson's diseases New York and London: Plenum Press, 1998: 587-95. (Adv Behav Biol: 49)
-
(1998)
Progress in Alzheimer's and Parkinson's Diseases
, pp. 587-595
-
-
Weinstock, M.1
-
88
-
-
0031695710
-
Measuring response to treatment in Alzheimer's disease: What constitutes meaningful change?
-
Mohs RC, Ferris SH. Measuring response to treatment in Alzheimer's disease: what constitutes meaningful change? Int J Geriatric Psychopharmacol 1598; 1 Suppl, 1: S7-S14
-
(1598)
Int J Geriatric Psychopharmacol
, vol.1
, Issue.SUPPL. 1
-
-
Mohs, R.C.1
Ferris, S.H.2
-
89
-
-
0031755416
-
Rivastigmine. A review of its use in Alzeimer's disease
-
Spencer CM, Nable S, Rivastigmine. A review of its use in Alzeimer's disease. Drugs Aging 1998; 13: 391-411
-
(1998)
Drugs Aging
, vol.13
, pp. 391-411
-
-
Spencer, C.M.1
Nable, S.2
-
90
-
-
0033528436
-
Efficacy and safely of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial
-
Rosler M, Anand R, Cicin-Sain A, et al. Efficacy and safely of rivastigmine in patients with Alzheimer's disease: international randomised controlled trial. BMJ 1999; 318 (7184): 633-8
-
(1999)
BMJ
, vol.318
, Issue.7184
, pp. 633-638
-
-
Rosler, M.1
Anand, R.2
Cicin-Sain, A.3
-
91
-
-
0031983322
-
Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: An interim analysis of the results of a US multicentre open-label extension study
-
Rogers SL, Friedhoff LT. Long-term efficacy and safety of donepezil in the treatment of Alzheimer's disease: an interim analysis of the results of a US multicentre open-label extension study. Eur Neuropsychopharmacol 1998; 8: 67-75
-
(1998)
Eur Neuropsychopharmacol
, vol.8
, pp. 67-75
-
-
Rogers, S.L.1
Friedhoff, L.T.2
-
92
-
-
0032926540
-
The effects of donepezil in Alzheimer's disease - Results from a multinational trial
-
Burns A, Rossor M, Hecker J, et al. The effects of donepezil in Alzheimer's disease - results from a multinational trial. Dement Geriatr Cogn Disord 1999; 10: 237-44
-
(1999)
Dement Geriatr Cogn Disord
, vol.10
, pp. 237-244
-
-
Burns, A.1
Rossor, M.2
Hecker, J.3
-
93
-
-
0032928421
-
Neuropsychiatric symptoms and cholinergic therapy for Alzheimer's disease
-
Levy ML, Cummings JL, Kahn-Rose R. Neuropsychiatric symptoms and cholinergic therapy for Alzheimer's disease. Gerontology 1999; 45 Suppl. 1: 15-22
-
(1999)
Gerontology
, vol.45
, Issue.SUPPL. 1
, pp. 15-22
-
-
Levy, M.L.1
Cummings, J.L.2
Kahn-Rose, R.3
-
94
-
-
0025339542
-
Selective inhibition of human acetylcholinesterase by galanthamine in vitro and in vivo
-
Thomson T, Kewitz H, Selective inhibition of human acetylcholinesterase by galanthamine in vitro and in vivo. Life Sci 1990; 46: 1553-8
-
(1990)
Life Sci
, vol.46
, pp. 1553-1558
-
-
Thomson, T.1
Kewitz, H.2
-
95
-
-
0028219789
-
Influence of the cholinesterase inhibitor galanthamine hydrobromide on normal sleep
-
Riemann D, Gann H, Dressing H, et al. Influence of the cholinesterase inhibitor galanthamine hydrobromide on normal sleep. Psychiatr Res 1994; 51: 253-67
-
(1994)
Psychiatr Res
, vol.51
, pp. 253-267
-
-
Riemann, D.1
Gann, H.2
Dressing, H.3
-
96
-
-
0027396643
-
Safety and efficacy of oral physostigmine in the treatment of Alzheimer's disease
-
Sano M, Bell K, Marder K, et al. Safety and efficacy of oral physostigmine in the treatment of Alzheimer's disease. Clin Neuropharmacol 1993; 16: 61-9
-
(1993)
Clin Neuropharmacol
, vol.16
, pp. 61-69
-
-
Sano, M.1
Bell, K.2
Marder, K.3
-
97
-
-
0032513106
-
Safety and tolerability of metrifonate in patents with Alzheimer's disease: Results of maximum tolerated dose study
-
Cutler NR, Jhee SS, Cyrus P, et al. Safety and tolerability of metrifonate in patents with Alzheimer's disease: results of maximum tolerated dose study. Life Sci 1998; 62: 1433-41
-
(1998)
Life Sci
, vol.62
, pp. 1433-1441
-
-
Cutler, N.R.1
Jhee, S.S.2
Cyrus, P.3
-
98
-
-
0023248810
-
Molecular forms of butyrylcholinesterase in the human neocortex during development und degeneration of the cortical cholinergic system
-
Atack JR, Perry EK, Bonham JR, et al. Molecular forms of butyrylcholinesterase in the human neocortex during development und degeneration of the cortical cholinergic system. J Neurochem 1987; 48 (6): 1687-92
-
(1987)
J Neurochem
, vol.48
, Issue.6
, pp. 1687-1692
-
-
Atack, J.R.1
Perry, E.K.2
Bonham, J.R.3
-
99
-
-
0031646338
-
Tolerability profiles of AChEIs: A critical component of care for Alzheimer's disease patients
-
Cutler NR, Sramek JJ. Tolerability profiles of AChEIs: a critical component of care for Alzheimer's disease patients. Int J Geriatric Psychopharmacol 1998; 1 Suppl. 1: S20-S25
-
(1998)
Int J Geriatric Psychopharmacol
, vol.1
, Issue.SUPPL. 1
-
-
Cutler, N.R.1
Sramek, J.J.2
-
100
-
-
0023197078
-
Effects of oral physostigmine in Alzheimer's disease
-
Stern Y, Sano M, Mayeux R. Effects of oral physostigmine in Alzheimer's disease. Ann Neurol 1987; 22: 306-10
-
(1987)
Ann Neurol
, vol.22
, pp. 306-310
-
-
Stern, Y.1
Sano, M.2
Mayeux, R.3
-
101
-
-
0020633185
-
Oral physostigmine and lecithin improve memory in Alzheimer's disease
-
Thal LJ, Fuld PA, Masur DM, et al. Oral physostigmine and lecithin improve memory in Alzheimer's disease. Ann Neurol 1983; 13: 491-6
-
(1983)
Ann Neurol
, vol.13
, pp. 491-496
-
-
Thal, L.J.1
Fuld, P.A.2
Masur, D.M.3
-
102
-
-
0024589925
-
Physostigmine, tacrine and metrifonate: The effect of multiple doses on acetylcholine metabolism in rat brain
-
Hallak M, Giacobini E. Physostigmine, tacrine and metrifonate: the effect of multiple doses on acetylcholine metabolism in rat brain. Neuropharmacology 1989; 28: 199-206
-
(1989)
Neuropharmacology
, vol.28
, pp. 199-206
-
-
Hallak, M.1
Giacobini, E.2
-
104
-
-
0030014585
-
An inverted U shaped curve for heptyl-physostigmine on radial maze performance in rats: Comparison with other cholinesternse inhibitors
-
Braida D, Paladini E, Griffini P, et al. An inverted U shaped curve for heptyl-physostigmine on radial maze performance in rats: comparison with other cholinesternse inhibitors. Eur J Pharmacol 1996; 302: 13-20
-
(1996)
Eur J Pharmacol
, vol.302
, pp. 13-20
-
-
Braida, D.1
Paladini, E.2
Griffini, P.3
-
105
-
-
0027386197
-
Antiammnestic and cholinomimetic side effects of the cholinesterase inhibitors, physostigmine, tacrine and NIK-247 in rats
-
Yoshida S, Suzuki N. Antiammnestic and cholinomimetic side effects of the cholinesterase inhibitors, physostigmine, tacrine and NIK-247 in rats. Eur J Phatmacol 1993; 150: 117-24
-
(1993)
Eur J Phatmacol
, vol.150
, pp. 117-124
-
-
Yoshida, S.1
Suzuki, N.2
-
106
-
-
0028062912
-
Characterization of a novel muscarinic receptor agonist, YM796: Comparison with cholinesterase inhibitors in vivo pharmacological studies
-
Wanibuchi F, Nishida T, Yamashita H, et al. Characterization of a novel muscarinic receptor agonist, YM796: comparison with cholinesterase inhibitors in vivo pharmacological studies. Eur J Phramacol 1994; 265: 151-8
-
(1994)
Eur J Phramacol
, vol.265
, pp. 151-158
-
-
Wanibuchi, F.1
Nishida, T.2
Yamashita, H.3
-
107
-
-
0032101015
-
Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities
-
Cheng DH, Tang XC. Comparative studies of huperzine A, E2020, and tacrine on behavior and cholinesterase activities. Pharmacol Biochem Behav 1998; 60: 377-86
-
(1998)
Pharmacol Biochem Behav
, vol.60
, pp. 377-386
-
-
Cheng, D.H.1
Tang, X.C.2
-
108
-
-
0020955530
-
Memory retention: Potentiation of cholinergic drug combinations in mice
-
Flood JF, Smith GE, Cherkin A. Memory retention: potentiation of cholinergic drug combinations in mice. Neurobiol Aging 1983; 4: 37-43
-
(1983)
Neurobiol Aging
, vol.4
, pp. 37-43
-
-
Flood, J.F.1
Smith, G.E.2
Cherkin, A.3
-
109
-
-
0026480336
-
Alzheimer's patients should he included in phase I clinical trials to evaluate compounds for Alzheimer's disease
-
Cutler NR, Sramek JJ, Murphy MF, et al. Alzheimer's patients should he included in phase I clinical trials to evaluate compounds for Alzheimer's disease. J Geriatr Psychiatry Neurol 1992; 5: 192-4
-
(1992)
J Geriatr Psychiatry Neurol
, vol.5
, pp. 192-194
-
-
Cutler, N.R.1
Sramek, J.J.2
Murphy, M.F.3
-
110
-
-
0029766994
-
Efficacy and safety results of the early phase studies with Exelon™ (ENA-713) in Alzheimer's disease: An overview
-
Anand R, Gharabawi G, Enz A. Efficacy and safety results of the early phase studies with Exelon™ (ENA-713) in Alzheimer's disease: an overview. J Drug Dev Clin Pract 1996; 8: 1-8
-
(1996)
J Drug Dev Clin Pract
, vol.8
, pp. 1-8
-
-
Anand, R.1
Gharabawi, G.2
Enz, A.3
|