ATP inhibits hydroxyl radical formation and the inflammatory response of stimulated whole blood even under circumstances of severe oxidative stress

Free Radical Research

Volumn 40, Issue 1, 2006, Pages 53-58

  Swennen, Els L R ^a   Dagnelie, Pieter C ^a   Bast, Aalt ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

ATP; Blood; Cytokines; Hydroxyl radicals; LPS; Oxidative stress

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; PHYTOHEMAGGLUTININ; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; ELECTRON SPIN RESONANCE; FEMALE; FENTON REACTION; HUMAN; INFLAMMATION; MALE; OXIDATIVE STRESS; SIMULATION; SPIN TRAPPING;

ADENOSINE TRIPHOSPHATE; ADULT; BLOOD; BLOOD CELLS; CYTOKINES; ELECTRON SPIN RESONANCE SPECTROSCOPY; FEMALE; HUMANS; HYDROXYL RADICAL; INTERLEUKIN-10; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MIDDLE AGED; OXIDATIVE STRESS; PHYTOHEMAGGLUTININS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 29744448196     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760500364298     Document Type: Article

References (29)

1. Boots, AW Haenen, GR and Bast, A. (2003) Oxidant metabolism in chronic obstructive pulmonary disease Eur Respir J Suppl, 46, pp. 14s - 27s.
2. Repine, JE Bast, A and Lankhorst, I. (1997) Oxidative stress in chronic obstructive pulmonary disease. Oxidative stress study group Am J Respir Crit Care Med, 156, pp. 341 - 357.
3. Morcillo, EJ Estrela, J and Cortijo, J. (1999) Oxidative stress and pulmonary inflammation: Pharmacological intervention with antioxidants Pharmacol Res, 40, pp. 393 - 404.
4. MacNee, W. (2001) Oxidative stress and lung inflammation in airways disease Eur J Pharmacol, 429, pp. 195 - 207.
5. Mantovani, G Maccio, A Madeddu, C Mura, L Gramignano, G Lusso, MR Massa, E Mocci, M and Serpe, R. (2003) Antioxidant agents are effective in inducing lymphocyte progression through cell cycle in advanced cancer patients: Assessment of the most important laboratory indexes of cachexia and oxidative stress J Mol Med, 81, pp. 664 - 673.
6. Gackowski, D Banaszkiewicz, Z Rozalski, R Jawien, A and Olinski, R. (2002) Persistent oxidative stress in colorectal carcinoma patients Int J Cancer, 101, pp. 395 - 397.
7. Gilgun-Sherki, Y Melamed, E and Offen, D. (2001) Oxidative stress induced-neurodegenerative diseases: The need for antioxidants that penetrate the blood brain barrier Neuropharmacology, 40, pp. 959 - 975.
8. Agar, J and Durham, H. (2003) Relevance of oxidative injury in the pathogenesis of motor neuron diseases Amyotroph Lateral Scler Other Motor Neuron Disord, 4, pp. 232 - 242.
9. Molavi, B and Mehta, JL. (2004) Oxidative stress in cardiovascular disease: Molecular basis of its deleterious effects, its detection, and therapeutic considerations Curr Opin Cardiol, 19, pp. 488 - 493.
10. Bast, A Haenen, GR and Doelman, CJ. (1991) Oxidants and antioxidants: State of the art Am J Med, 91, pp. 2S - 13S.
11. Rahman, I and MacNee, W. (1998) Role of transcription factors in inflammatory lung diseases Thorax, 53, pp. 601 - 612.
12. Rahman, I and MacNee, W. (2000) Oxidative stress and regulation of glutathione in lung inflammation Eur Respir J, 16, pp. 534 - 554.
13. Grahames, CB Michel, AD Chessell, IP and Humphrey, PP. (1999) Pharmacological characterization of ATP- and LPS-induced IL-1beta release in human monocytes Br J Pharmacol, 127, pp. 1915 - 1921.
14. Sanz, JM and Di Virgilio, F. (2000) Kinetics and mechanism of ATP-dependent IL-1 beta release from microglial cells J Immunol, 164, pp. 4893 - 4898.
15. Perregaux, DG McNiff, P Laliberte, R Conklyn, M and Gabel, CA. (2000) ATP acts as an agonist to promote stimulus-induced secretion of IL-1 beta and IL-18 in human blood J Immunol, 165, pp. 4615 - 4623.
16. Hide, I Tanaka, M Inoue, A Nakajima, K Kohsaka, S Inoue, K and Nakata, Y. (2000) Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia J Neurochem, 75, pp. 965 - 972.
17. Shigemoto-Mogami, Y Koizumi, S Tsuda, M Ohsawa, K Kohsaka, S and Inoue, K. (2001) Mechanisms underlying extracellular ATP-evoked interleukin-6 release in mouse microglial cell line, MG-5 J Neurochem, 78, pp. 1339 - 1349.
18. Ferrari, D Chiozzi, P Falzoni, S Hanau, S and Di Virgilio, F. (1997) Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin J Exp Med, 185, pp. 579 - 582.
19. Swennen, EL Bast, A and Dagnelie, PC. (2005) Immunoregulatory effects of adenosine 5′- triphosphate on cytokine release from stimulated whole blood Eur J Immunol, 35, pp. 852 - 858.
20. Van der Vliet, A and Bast, A. (1992) Effect of oxidative stress on receptors and signal transmission Chem Biol Interact, 85, pp. 95 - 116.
21. Bast, A. (1994) Antioxidant pharmacotherapy DN&P, 7(8).
22. Kaul, N and Forman, HJ. (1996) Activation of NF kappa B by the respiratory burst of macrophages Free Radic Biol Med, 21, pp. 401 - 405.
23. Chandrasekar, B Colston, JT de la Rosa, SD Rao, PP and Freeman, GL. (2003) TNF-alpha and H2O2 induce IL-18 and IL-18R beta expression in cardiomyocytes via NF-kappa B activation Biochem Biophys Res Commun, 303, pp. 1152 - 1158.
24. Ikeda, M Hirose, Y Miyoshi, K and Kodama, H. (2002) Nuclear factor kappa B (NF-kappaB) activation by hydrogen peroxide in human epidermal keratinocytes and the restorative effect of interleukin-10 J Dermatol Sci, 28, pp. 159 - 170.
25. Schoonbroodt, S and Piette, J. (2000) Oxidative stress interference with the nuclear factor-kappa B activation pathways Biochem Pharmacol, 60, pp. 1075 - 1083.
26. Bowie, A and O'Neill, LA. (2000) Oxidative stress and nuclear factor-kappaB activation: A reassessment of the evidence in the light of recent discoveries Biochem Pharmacol, 59, pp. 13 - 23.
27. Bonizzi, G and Karin, M. (2004) The two NF-kappa B activation pathways and their role in innate and adaptive immunity Trends Immunol, 25, pp. 280 - 288.
28. Barnes, PJ and Karin, M. (1997) Nuclear factor-kappa B: A pivotal transcription factor in chronic inflammatory diseases N Engl J Med, 336, pp. 1066 - 1071.
29. Jiang, Q Akashi, S Miyake, K and Petty, HR. (2000) Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B J Immunol, 165, pp. 3541 - 3544.