Development of a metabolic network design and optimization framework incorporating implementation constraints: A succinate production case study

Metabolic Engineering

Volumn 8, Issue 1, 2006, Pages 46-57

  Cox, Steven J ^a   Shalel Levanon, Sagit ^b   Sanchez, Ailen ^a   Lin, Henry ^a   Peercy, Brad ^a   Bennett, George N ^b   San, Ka Yiu ^a  

^a Rice University   (United States)

^b RICE UNIVERSITY   (United States)

Author keywords

Elementary flux mode; Escherichia coli; Operational constraints; Pathway design and optimization; Sensitivity; Succinate production

Indexed keywords

CONSTRAINT THEORY; MAGNETIC FLUX; MATHEMATICAL MODELS; NUMERICAL METHODS; OPTIMIZATION; PERTURBATION TECHNIQUES; SENSITIVITY ANALYSIS;

OPERATIONAL CONSTRAINTS; PATHWAY DESIGN AND OPTIMIZATION; SENSITIVITY; SUCCINATE PRODUCTION;

METABOLISM;

SUCCINIC ACID;

ARTICLE; BIOTECHNOLOGY; CONCEPTUAL FRAMEWORK; ESCHERICHIA COLI; METABOLIC ENGINEERING; PREDICTION; PRIORITY JOURNAL; QUANTUM YIELD; THEORETICAL MODEL;

COMPUTER SIMULATION; ESCHERICHIA COLI; MODELS, BIOLOGICAL; SUCCINIC ACID;

ESCHERICHIA COLI;

EID: 29644446809     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2005.09.006     Document Type: Article

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