메뉴 건너뛰기




Volumn 89, Issue 6, 2004, Pages 3020-3026

Type II gonadotropin-releasing hormone stimulates p38 mitogen-activated protein kinase and apoptosis in ovarian cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; GROWTH HORMONE RELEASING FACTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

EID: 2942685557     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-031871     Document Type: Conference Paper
Times cited : (34)

References (54)
  • 2
    • 0028290780 scopus 로고
    • The epidemiology of ovarian carcinoma and the current status of tumor markers to detect disease
    • Herbst AL 1994 The epidemiology of ovarian carcinoma and the current status of tumor markers to detect disease. Am J Obstet Gynecol 170:1099-1105
    • (1994) Am J Obstet Gynecol , vol.170 , pp. 1099-1105
    • Herbst, A.L.1
  • 3
    • 0032477328 scopus 로고    scopus 로고
    • Hormonal etiology of epithelial ovarian cancer, with a hypothesis concerning the role of androgens and progesterone
    • Risch HA 1998 Hormonal etiology of epithelial ovarian cancer, with a hypothesis concerning the role of androgens and progesterone. J Natl Cancer Inst 90:1774-1786
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1774-1786
    • Risch, H.A.1
  • 4
    • 0027978383 scopus 로고
    • Epidemiology, etiology, and fertility drugs in ovarian epithelial carcinoma: Where are we today?
    • Shoham Z 1994 Epidemiology, etiology, and fertility drugs in ovarian epithelial carcinoma: where are we today? Fertil Steril 62:433-448
    • (1994) Fertil Steril , vol.62 , pp. 433-448
    • Shoham, Z.1
  • 5
    • 0032739426 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone analogs: Their impact on the control of tumorigenesis
    • Schally AV 1999 Luteinizing hormone-releasing hormone analogs: their impact on the control of tumorigenesis. Peptides 20:1247-1262
    • (1999) Peptides , vol.20 , pp. 1247-1262
    • Schally, A.V.1
  • 7
    • 0025372326 scopus 로고
    • Endocrine treatment of breast cancer in women
    • Santen R, Manni A, Harvey H, Redmond C 1990 Endocrine treatment of breast cancer in women. Endocr Rev 11:221-265
    • (1990) Endocr Rev , vol.11 , pp. 221-265
    • Santen, R.1    Manni, A.2    Harvey, H.3    Redmond, C.4
  • 8
    • 0036342019 scopus 로고    scopus 로고
    • Treating relapsed epithelial ovarian cancer with luteinizing hormone-releasing agonist (goserelin) after failure of chemotherapy
    • Zidan J, Zohar S, Mijiritzky I, Kral S, Bilenca B 2002 Treating relapsed epithelial ovarian cancer with luteinizing hormone-releasing agonist (goserelin) after failure of chemotherapy. Isr Med Assoc J 4:597-599
    • (2002) Isr Med Assoc J , vol.4 , pp. 597-599
    • Zidan, J.1    Zohar, S.2    Mijiritzky, I.3    Kral, S.4    Bilenca, B.5
  • 10
    • 85047684264 scopus 로고    scopus 로고
    • Minireview: GnRH and GnRH receptor genes in the human genome
    • Neill JD 2002 Minireview: GnRH and GnRH receptor genes in the human genome. Endocrinology 143:737-743
    • (2002) Endocrinology , vol.143 , pp. 737-743
    • Neill, J.D.1
  • 11
    • 0036965115 scopus 로고    scopus 로고
    • Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cancer cells and effects of GnRH-II on tumor cell proliferation
    • Grundker C, Gunthert AR, Millar RP, Emons G 2002 Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cancer cells and effects of GnRH-II on tumor cell proliferation. J Clin Endocrinol Metab 87:1427-1430
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1427-1430
    • Grundker, C.1    Gunthert, A.R.2    Millar, R.P.3    Emons, G.4
  • 12
    • 0034119581 scopus 로고    scopus 로고
    • Activation of MAPK cascades by G-protein-coupled receptors: The case of gonadotropin-releasing hormone receptor
    • Naor Z, Benard O, Seger R 2000 Activation of MAPK cascades by G-protein-coupled receptors: the case of gonadotropin-releasing hormone receptor. Trends Endocrinol Metab 11:91-99
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 91-99
    • Naor, Z.1    Benard, O.2    Seger, R.3
  • 13
    • 0035676783 scopus 로고    scopus 로고
    • Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor
    • Kraus S, Naor Z, Seger R 2001 Intracellular signaling pathways mediated by the gonadotropin-releasing hormone (GnRH) receptor. Arch Med Res 32:499-509
    • (2001) Arch Med Res , vol.32 , pp. 499-509
    • Kraus, S.1    Naor, Z.2    Seger, R.3
  • 14
    • 0029043582 scopus 로고
    • How MAP kinases are regulated
    • Cobb MH, Goldsmith EJ 1995 How MAP kinases are regulated. J Biol Chem 270:14843-14846
    • (1995) J Biol Chem , vol.270 , pp. 14843-14846
    • Cobb, M.H.1    Goldsmith, E.J.2
  • 15
    • 0032910168 scopus 로고    scopus 로고
    • Organization and regulation of mitogen-activated protein kinase signaling pathways
    • Garrington TP, Johnson GL 1999 Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr Opin Cell Biol 11:211-218
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 211-218
    • Garrington, T.P.1    Johnson, G.L.2
  • 16
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson GL, Lapadat R 2002 Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298:1911-1912
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 17
    • 0032103332 scopus 로고    scopus 로고
    • Ets transcription factors: Nuclear effectors of the Ras-MAP-kinase signaling pathway
    • Wasylyk B, Hagman J, Gutierrez-Hartmann A 1998 Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway. Trends Biochem Sci 23:213-216
    • (1998) Trends Biochem Sci , vol.23 , pp. 213-216
    • Wasylyk, B.1    Hagman, J.2    Gutierrez-Hartmann, A.3
  • 18
    • 0029328342 scopus 로고
    • Transcriptional control by protein phosphorylation: Signal transmission from the cell surface to the nucleus
    • Karin M, Hunter T 1995 Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus. Curr Biol 5:747-757
    • (1995) Curr Biol , vol.5 , pp. 747-757
    • Karin, M.1    Hunter, T.2
  • 21
    • 0034704389 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone activates mitogen-activated protein kinase in human ovarian and placental cells
    • Kang SK, Tai C-J, Cheng KW, Leung PCK 2000 Gonadotropin-releasing hormone activates mitogen-activated protein kinase in human ovarian and placental cells. Mol Cell Endocrinol 170:143-151
    • (2000) Mol Cell Endocrinol , vol.170 , pp. 143-151
    • Kang, S.K.1    Tai, C.-J.2    Cheng, K.W.3    Leung, P.C.K.4
  • 22
    • 0035961978 scopus 로고    scopus 로고
    • Differential expression of activin/inhibin subunit and activin receptor mRNAs in normal and neoplastic ovarian surface epithelium (OSE)
    • Choi KC, Kang SK, Nathwani PS, Cheng KW, Auersperg N, Leung PC 2001 Differential expression of activin/inhibin subunit and activin receptor mRNAs in normal and neoplastic ovarian surface epithelium (OSE). Mol Cell Endocrinol 174:99-110
    • (2001) Mol Cell Endocrinol , vol.174 , pp. 99-110
    • Choi, K.C.1    Kang, S.K.2    Nathwani, P.S.3    Cheng, K.W.4    Auersperg, N.5    Leung, P.C.6
  • 25
    • 0036095452 scopus 로고    scopus 로고
    • Follicle-stimulating hormone activates mitogen-activated protein kinase in preneoplastic and neoplastic ovarian surface epithelial cells
    • Choi KC, Kang SK, Tai CJ, Auersperg N, Leung PC 2002 Follicle-stimulating hormone activates mitogen-activated protein kinase in preneoplastic and neoplastic ovarian surface epithelial cells. J Clin Endocrinol Metab 87:2245-2253
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2245-2253
    • Choi, K.C.1    Kang, S.K.2    Tai, C.J.3    Auersperg, N.4    Leung, P.C.5
  • 26
    • 0030444631 scopus 로고    scopus 로고
    • Activin inhibits basal and androgen-stimulated proliferation and induces apoptosis in the human prostatic cancer cell line, LNCaP
    • Wang QF, Tilly KI, Tilly JL, Preffer F, Schneyer AL, Crowley WFJ, Sluss PM 1996 Activin inhibits basal and androgen-stimulated proliferation and induces apoptosis in the human prostatic cancer cell line, LNCaP. Endocrinology 137:5476-5483
    • (1996) Endocrinology , vol.137 , pp. 5476-5483
    • Wang, Q.F.1    Tilly, K.I.2    Tilly, J.L.3    Preffer, F.4    Schneyer, A.L.5    Crowley, W.F.J.6    Sluss, P.M.7
  • 27
    • 0034740086 scopus 로고    scopus 로고
    • Expression and antiproliferative effect of a second form of gonadotropin-releasing hormone in normal and neoplastic ovarian surface epithelial cells
    • Choi KC, Auersperg N, Leung PC 2001 Expression and antiproliferative effect of a second form of gonadotropin-releasing hormone in normal and neoplastic ovarian surface epithelial cells. J Clin Endocrinol Metab 86:5075-5078
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5075-5078
    • Choi, K.C.1    Auersperg, N.2    Leung, P.C.3
  • 28
    • 0035009393 scopus 로고    scopus 로고
    • Estradiol upregulates antiapoptotic Bcl-2 messenger ribonucleic acid and protein in tumorigenic ovarian surface epithelium cells
    • Choi KC, Kang SK, Tai CJ, Auersperg N, Leung PC 2001 Estradiol upregulates antiapoptotic Bcl-2 messenger ribonucleic acid and protein in tumorigenic ovarian surface epithelium cells. Endocrinology 142:2351-2360
    • (2001) Endocrinology , vol.142 , pp. 2351-2360
    • Choi, K.C.1    Kang, S.K.2    Tai, C.J.3    Auersperg, N.4    Leung, P.C.5
  • 29
    • 0035000225 scopus 로고    scopus 로고
    • The regulation of apoptosis by activin and transforming growth factor-β in early neoplastic and tumorigenic ovarian surface epithelium
    • Choi KC, Kang SK, Tai CJ, Auersperg N, Leung PC 2001 The regulation of apoptosis by activin and transforming growth factor-β in early neoplastic and tumorigenic ovarian surface epithelium. J Clin Endocrinol Metab 86:2125-2135
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2125-2135
    • Choi, K.C.1    Kang, S.K.2    Tai, C.J.3    Auersperg, N.4    Leung, P.C.5
  • 30
    • 0035145550 scopus 로고    scopus 로고
    • Comparison of the effects of GnRH-I and GnRH-II on HCG synthesis and secretion by first trimester trophoblast
    • Islami D, Chardonnens D, Campana A, Bischof P 2001 Comparison of the effects of GnRH-I and GnRH-II on HCG synthesis and secretion by first trimester trophoblast. Mol Hum Reprod 7:3-9
    • (2001) Mol Hum Reprod , vol.7 , pp. 3-9
    • Islami, D.1    Chardonnens, D.2    Campana, A.3    Bischof, P.4
  • 33
    • 0038069320 scopus 로고    scopus 로고
    • GnRH II and type II GnRH receptors
    • Millar RP 2003 GnRH II and type II GnRH receptors. Trends Endocrinol Metab 14:35-43
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 35-43
    • Millar, R.P.1
  • 34
    • 0038627514 scopus 로고    scopus 로고
    • Multi-factorial role of GnRH-I and GnRH-II in the human ovary
    • Leung PCK, Cheng CK, Zhu X-M 2003 Multi-factorial role of GnRH-I and GnRH-II in the human ovary. Mol Cell Endocrinol 202:145-153
    • (2003) Mol Cell Endocrinol , vol.202 , pp. 145-153
    • Leung, P.C.K.1    Cheng, C.K.2    Zhu, X.-M.3
  • 35
    • 0034810482 scopus 로고    scopus 로고
    • A gonadotropin-releasing hormone (GnRH) receptor specific for GnRH II in primates
    • Neill JD, Duck LW, Sellers JC, Musgrove LC 2001 A gonadotropin-releasing hormone (GnRH) receptor specific for GnRH II in primates. Biochem Biophys Res Commun 282:1012-1018
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 1012-1018
    • Neill, J.D.1    Duck, L.W.2    Sellers, J.C.3    Musgrove, L.C.4
  • 36
    • 0037379479 scopus 로고    scopus 로고
    • Action of gonadotropin-releasing hormone n on the baboon ovary
    • Siler-Khodr TM, Grayson M, Eddy CA 2003 Action of gonadotropin-releasing hormone n on the baboon ovary. Biol Reprod 68:1150-1156
    • (2003) Biol Reprod , vol.68 , pp. 1150-1156
    • Siler-Khodr, T.M.1    Grayson, M.2    Eddy, C.A.3
  • 37
  • 38
    • 0032230247 scopus 로고    scopus 로고
    • Stimulation of Jun N-terminal kinase (JNK) by gonadotropin-releasing hormone in pituitary αT3-1 cell line is mediated by protein kinase C, c-Src, and CDC42
    • Levi NL, Hanoch T, Benard O, Rozenblat M, Harris D, Reiss N, Naor Z, Seger R 1998 Stimulation of Jun N-terminal kinase (JNK) by gonadotropin- releasing hormone in pituitary αT3-1 cell line is mediated by protein kinase C, c-Src, and CDC42. Mol Endocrinol 12:815-824
    • (1998) Mol Endocrinol , vol.12 , pp. 815-824
    • Levi, N.L.1    Hanoch, T.2    Benard, O.3    Rozenblat, M.4    Harris, D.5    Reiss, N.6    Naor, Z.7    Seger, R.8
  • 39
    • 0036185866 scopus 로고    scopus 로고
    • GnRH activates ERK1/2 leading to the induction of c-fos and LHβ protein expression in LβT2 Cells
    • Liu F, Austin DA, Mellon PL, Olefsky JM, Webster NJG 2002 GnRH activates ERK1/2 leading to the induction of c-fos and LHβ protein expression in LβT2 Cells. Mol Endocrinol 16:419-434
    • (2002) Mol Endocrinol , vol.16 , pp. 419-434
    • Liu, F.1    Austin, D.A.2    Mellon, P.L.3    Olefsky, J.M.4    Webster, N.J.G.5
  • 40
    • 0030944161 scopus 로고    scopus 로고
    • Mechanism of mitogen-activated protein kinase activation by gonadotropin-releasing hormone in the pituitary αT3-1 cell line: Differential roles of calcium and protein kinase C
    • Reiss N, Llevi LN, Shacham S, Harris D, Seger R, Naor Z 1997 Mechanism of mitogen-activated protein kinase activation by gonadotropin-releasing hormone in the pituitary αT3-1 cell line: differential roles of calcium and protein kinase C. Endocrinology 138:1673-1682
    • (1997) Endocrinology , vol.138 , pp. 1673-1682
    • Reiss, N.1    Llevi, L.N.2    Shacham, S.3    Harris, D.4    Seger, R.5    Naor, Z.6
  • 41
    • 0032963917 scopus 로고    scopus 로고
    • Activation of the p38 mitogen-activated protein kinase pathway by gonadotropin-releasing hormone
    • Roberson MS, Zhang T, Li HL, Mulvaney JM 1999 Activation of the p38 mitogen-activated protein kinase pathway by gonadotropin-releasing hormone. Endocrinology 140:1310-1318
    • (1999) Endocrinology , vol.140 , pp. 1310-1318
    • Roberson, M.S.1    Zhang, T.2    Li, H.L.3    Mulvaney, J.M.4
  • 42
    • 0032723879 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase/extracellular signal-regulated kinase cascade in gonadotropin-releasing hormone-induced growth inhibition of a human ovarian cancer cell line
    • Kimura A, Ohmichi M, Kurachi H, Ikegami H, Hayakawa J, Tasaka K, Kanda Y, Nishio Y, Jikihara H, Matsuura N, Murata Y 1999 Role of mitogen-activated protein kinase/extracellular signal-regulated kinase cascade in gonadotropin-releasing hormone-induced growth inhibition of a human ovarian cancer cell line. Cancer Res 59:5133-5142
    • (1999) Cancer Res , vol.59 , pp. 5133-5142
    • Kimura, A.1    Ohmichi, M.2    Kurachi, H.3    Ikegami, H.4    Hayakawa, J.5    Tasaka, K.6    Kanda, Y.7    Nishio, Y.8    Jikihara, H.9    Matsuura, N.10    Murata, Y.11
  • 43
    • 0034992648 scopus 로고    scopus 로고
    • Effects of salmon GnRH and chicken GnRH-II on testicular apoptosis in goldfish (Carassius auratus)
    • Andreu-Vieyra C, Habibi H 2001 Effects of salmon GnRH and chicken GnRH-II on testicular apoptosis in goldfish (Carassius auratus). Comp Biochem Physiol B Biochem Mol Biol 129:483-487
    • (2001) Comp Biochem Physiol B Biochem Mol Biol , vol.129 , pp. 483-487
    • Andreu-Vieyra, C.1    Habibi, H.2
  • 44
    • 0028346169 scopus 로고
    • Direct growth inhibition of human endometrial cancer cells by the gonadotropin-releasing hormone antagonist SB-75: Role of apoptosis
    • Kleinman D, Douvdevani A, Serially A, Levy J, Sharoni Y 1994 Direct growth inhibition of human endometrial cancer cells by the gonadotropin- releasing hormone antagonist SB-75: role of apoptosis. Am J Obstet Gynecol 170:96-102
    • (1994) Am J Obstet Gynecol , vol.170 , pp. 96-102
    • Kleinman, D.1    Douvdevani, A.2    Serially, A.3    Levy, J.4    Sharoni, Y.5
  • 45
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson C 1995 Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.1
  • 47
    • 0031615957 scopus 로고    scopus 로고
    • Induction of apoptosis in ovarian carcinoma cell line by gonadotropin-releasing hormone agonist
    • Motomura S 1998 Induction of apoptosis in ovarian carcinoma cell line by gonadotropin-releasing hormone agonist. Kurume Med J 45:27-32
    • (1998) Kurume Med J , vol.45 , pp. 27-32
    • Motomura, S.1
  • 48
    • 0033756722 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone induces nuclear factor κB-activation and inhibits apoptosis in ovarian cancer cells
    • Grundker C, Schulz K, Gunthert AR, Emons G 2000 Luteinizing hormone-releasing hormone induces nuclear factor κB-activation and inhibits apoptosis in ovarian cancer cells. J Clin Endocrinol Metab 85:3815-3820
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3815-3820
    • Grundker, C.1    Schulz, K.2    Gunthert, A.R.3    Emons, G.4
  • 49
    • 0027303690 scopus 로고
    • Studies of the relationship between cell proliferation and cell death. III. AP-1 DNA-binding activity during concanavalin A-induced proliferation or dexamethasone-induced apoptosis of rat thymocytes
    • Sikora E, Grassilli E, Bellesia E, Troiano L, Franceschi C 1993 Studies of the relationship between cell proliferation and cell death. III. AP-1 DNA-binding activity during concanavalin A-induced proliferation or dexamethasone-induced apoptosis of rat thymocytes. Biochem Biophys Res Commun 192:386-391
    • (1993) Biochem Biophys Res Commun , vol.192 , pp. 386-391
    • Sikora, E.1    Grassilli, E.2    Bellesia, E.3    Troiano, L.4    Franceschi, C.5
  • 50
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian E, Karin M 2002 AP-1 as a regulator of cell life and death. Nat Cell Biol 4:E131-E136
    • (2002) Nat Cell Biol , vol.4
    • Shaulian, E.1    Karin, M.2
  • 51
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • Raingeaud J, Gupta S, Dickens M, Han J 1995 Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270: 7420-7426
    • (1995) J Biol Chem , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Dickens, M.3    Han, J.4
  • 52
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin M 1995 The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270:16483-16486
    • (1995) J Biol Chem , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 53
    • 0029062123 scopus 로고
    • A role for mitogen-activated protein kinase in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonadotropin-releasing hormone
    • Roberson M, Misra-Press A, Laurance M, Stork P, Maurer R 1995 A role for mitogen-activated protein kinase in mediating activation of the glycoprotein hormone alpha-subunit promoter by gonadotropin-releasing hormone. Mol Cell Biol 15:3531-3539
    • (1995) Mol Cell Biol , vol.15 , pp. 3531-3539
    • Roberson, M.1    Misra-Press, A.2    Laurance, M.3    Stork, P.4    Maurer, R.5
  • 54
    • 0035171066 scopus 로고    scopus 로고
    • Protein kinase C-independent stimulation of activator protein-1 and c-Jun N-terminal kinase activity in human endometrial cancer cells by the LHRH agonist triptorelin
    • Grundker C, Schlotawa L, Viereck V, Emons G2001 Protein kinase C-independent stimulation of activator protein-1 and c-Jun N-terminal kinase activity in human endometrial cancer cells by the LHRH agonist triptorelin. Eur J Endocrinol 145:651-658
    • (2001) Eur J Endocrinol , vol.145 , pp. 651-658
    • Grundker, C.1    Schlotawa, L.2    Viereck, V.3    Emons, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.