Structural and ionic determinants of 5-nitro-2-(3-phenylpropylamino)-benzoic acid block of the CFTR chloride channel

British Journal of Pharmacology

Volumn 127, Issue 2, 1999, Pages 369-376

  Walsh, Kenneth B ^a   Long, Kathryn J ^a   Shen, Xufeng ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Arylaminobenzoates; CFTR Cl channels; SCN ; Site directed mutagenesis

Indexed keywords

5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; CHLORIDE; CHLORIDE CHANNEL; ION TRANSPORT AFFECTING AGENT; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; CHLORIDE CURRENT; DRUG BINDING; DRUG POTENCY; FEMALE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ANIMALS; CHLORIDE CHANNELS; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; MICROELECTRODES; MUTAGENESIS, SITE-DIRECTED; MUTAGENS; NITROBENZOATES; OOCYTES; PATCH-CLAMP TECHNIQUES; RNA, MESSENGER; STRUCTURE-ACTIVITY RELATIONSHIP; THIOCYANATES; XENOPUS LAEVIS;

EID: 0032986798     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702562     Document Type: Article

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