Role of TGF-β2 in the human hair cycle

Journal of Dermatological Science

Volumn 35, Issue 1, 2004, Pages 9-18

  Hibino, Toshihiko ^a   Nishiyama, Toshio ^a,b  

^a SHISEIDO RESEARCH CENTER   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

Apoptosis; Caspase; Catagen induction; Hair cycle; terminal deoxynucleotidyltransferase mediated deoxyuridine triphosphate biotin nick end labeling; TGF ; transforming growth factor ; TUNEL

Indexed keywords

ANDROGEN; ANDROSTANOLONE; CASPASE; HYDRANGEA EXTRACT; PLANT EXTRACT; STEROID 5ALPHA REDUCTASE; TESTOSTERONE; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG; TGFB2 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ALOPECIA; APOPTOSIS; CELL PROLIFERATION; ENZYME SYNTHESIS; EPITHELIUM CELL; HAIR FOLLICLE; HAIR GROWTH; HAIR LOSS; HUMAN; HYDRANGEA; MORPHOLOGY; NICK END LABELING; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; DRUG ANTAGONISM; IN VITRO STUDY; MALE; METABOLISM; PATHOPHYSIOLOGY;

ALOPECIA; CASPASES; DIHYDROTESTOSTERONE; HAIR FOLLICLE; HUMANS; MALE; TESTOSTERONE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2;

EID: 2942610814     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2003.12.003     Document Type: Review

References (57)

1. Jahoda C.A. Cellular and developmental aspects of androgenetic alopecia. Exp. Dermatol. 7:1998;235-248
2. Paus R., Handjiski B., Eichmuller S., Czarnetzki B.M. Chemotherapy-induced alopecia in mice. Induction by cyclophosphamide, inhibition by cyclosporine A, and modulation by dexamethasone. Am. J. Pathol. 144:1994;719-734
3. Galbraith G.M., Thiers B.H., Vasily D.B., Fudenberg H.H. Immunological profiles in alopecia areata. Br. J. Dermatol. 110:1984;163-170
4. Hsieh J.C., Sisk J.M., Jurutka P.W., Haussler C.A., Slater S.A., Haussler M.R., et al. Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling. J. Biol. Chem. 278:2003;38665-38674
5. Panteleyev A.A., Botchkareva N.V., Sundberg J.P., Christiano A.M., Paus R. The role of the hairless (hr) gene in the regulation of hair follicle catagen transformation. Am. J. Pathol. 155:1999;159-171
6. Yano K., Brown L.F., Lawler J., Miyakawa T., Detmar M. Thrombospondin-1 plays a critical role in the induction of hair follicle involution and vascular regression during the catagen phase. J. Invest. Dermatol. 120:2003;14-19
7. Botchkarev V.A., Welker P., Albers K.M., Botchkareva N.V., Metz M., Lewis G.R., et al. A new role for neurotrophin-3: involvement in the regulation of hair follicle regression (catagen). Am. J. Pathol. 153:1998;785-799
8. Botchkarev V.A., Botchkarev N.V., Welker P., Metz M., Lewin G.R., Subramaniam A., et al. A new role for neurotrophins: involvement of brain-derived neurotrophic factor and neurotrophin-4 in hair cycle control. Faseb. J. 13:1999;395-410
9. Botchkareva N.V., Botchkarev V.A., Welker P., Airaksinen M., Roth W., Suvanto P., et al. New roles for glial cell line-derived neurotrophic factor and neurturin: involvement in hair cycle control. Am. J. Pathol. 156:2000;1041-1053
10. Hebert J.M., Rosenquist T., Gotz J., Martin G.R. FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations. Cell. 78:1994;1017-1025
11. Suzuki S., Kato T., Takimoto H., Masui S., Oshima H., Ozawa K., et al. Localization of rat FGF-5 protein in skin macrophage-like cells and FGF-5S protein in hair follicle: possible involvement of two Fgf-5 gene products in hair growth cycle regulation. J. Invest. Dermatol. 111:1998;963-972
12. Suzuki S., Ota Y., Ozawa K., Imamura T. Dual-mode regulation of hair growth cycle by two Fgf-5 gene products. J. Invest. Dermatol. 114:2000;456-463
13. Foitzik K., Lindner G., Mueller-Roever S., Maurer M., Botchkareva N., Botchkarev V., et al. Control of murine hair follicle regression (catagen) by TGF-β1 in vivo. Faseb. J. 14:2000;752-760
14. Hardy M.H. The secret life of the hair follicle. Trends Genet. 8:1992;55-61
15. Kumar S. Mechanisms mediating caspase activation in cell death. Cell Death Differ. 6:1999;1060-1066
16. Schneider P., Tschopp J. Apoptosis induced by death receptors. Pharm. Acta Helv. 74:2000;281-286
17. Jiang X., Wang X. Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1. J. Biol. Chem. 275:2000;31199-31203
18. Eckhart L., Declercq W., Ban J., Rendl M., Lengauer B., Mayer C., et al. Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation. J. Invest. Dermatol. 115:2000;1148-1151
19. Eckhart L., Ban J., Fischer H., Tschachler E. Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation. Biochem. Biophys. Res. Commun. 277:2000;655-659
20. Lippens S., Kockx M., Knaapen M., Mortier L., Polakowska R., Verheyen A., et al. Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing. Cell Death Differ. 7:2000;1218-1224
21. Kuechle M.K., Predd H.M., Fleckman P., Dale B.A., Presland R.B. Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse. Cell Death Differ. 8:2001;868-870
22. Soma T., Ogo M., Suzuki J., Takahashi T., Hibino T. Analysis of apoptotic cell death in human hair follicles in vivo and in vitro. J. Invest. Dermatol. 111:1998;948-954
23. Chang H., Brown C.W., Matzuk M.M. Genetic analysis of the mammalian transforming growth factor-beta superfamily. Endocr. Rev. 23:2002;787-823
24. Moses H.L., Yang E.Y., Pietenpol J.A. TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights. Cell. 63:1990;245-247
25. Massague J., Blain S.W., Lo R.S. TGFbeta signaling in growth control, cancer, and heritable disorders. Cell. 103:2000;295-309
26. Shi Y., Massague J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell. 113:2003;685-700
27. Schuster N., Krieglstein K. Mechanisms of TGF-beta-mediated apoptosis. Cell Tiss. Res. 307:2002;1-14
28. Massague J. TGF-beta signal transduction. Annu. Rev. Biochem. 67:1998;753-791
29. Miyazono K. TGF-beta receptors and signal transduction. Int. J. Hematol. 65:1997;97-104
30. Moustakas A., Souchelnytskyi S., Heldin C.H. Smad regulation in TGF-beta signal transduction. J. Cell Sci. 114:2001;4359-4369
31. Jiang Z., Ninomiya-Tsuji J., Qian Y., Matsumoto K., Li X. Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol. Mol. Cell Biol. 22:2002;7158-7167
32. Wang C., Deng L., Hong M., Akkaraju G.R., Inonu J., Chen Z.J. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature. 412:2001;346-351
33. Holland P.M., Suzanne M., Campbell J.S., Noselli S., Cooper J.A. MKK7 is a stress-activated mitogen-activated protein kinase kinase functionally related to hemipterous. J. Biol. Chem. 272:1997;24994-24998
34. Hirai S., Noda K., Moriguchi T., Nishida E., Yamashita A., Deyama T., et al. Differential activation of two JNK activators, MKK7 and SEK1, by MKN28-derived nonreceptor serine/threonine kinase/mixed lineage kinase 2. J. Biol. Chem. 273:1998;7406-7412
35. Soma T., Tsuji Y., Hibino T. Involvement of transforming growth factor-beta2 in catagen induction during the human hair cycle. J. Invest. Dermatol. 118:2002;993-997
36. Tsuji Y., Denda S., Soma T., Raftery L., Momoi T., Hibino T. A potential suppressor of TGF-beta delays catagen progression in hair follicles. J. Invest. Dermatol. Symp. Proc. 8:2003;65-68
37. Shirakabe K., Yamaguchi K., Shibuya H., Irie K., Matsuda S., Moriguchi T., et al. TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase. J. Biol. Chem. 272:1997;8141-8144
38. Park H.J., Kim B.C., Kim S.J., Choi K.S. Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line. Hepatology. 35:2002;1360-1371
39. Tournier C., Hess P., Yang D.D., Xu J., Turner T.K., Nimnual A., et al. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science. 288:2000;870-874
40. Weston C.R., Davis R.J. The JNK signal transduction pathway. Curr. Opin. Genet. Develop. 12:2002;14-21
41. Aoki H., Kang P.M., Hampe J., Yoshimura K., Noma T., Matsuzaki M., et al. Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes. J. Biol. Chem. 277:2002;10244-10250
42. Cecconi F., Alvarrez-Balado G., Meyer B.I., Roth K.A., Gruss P. Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell. 94:1998;727-737
43. Yoshida H., Kong Y.Y., Yoshida R., Elia A.J., Hakem A., Hakem R., et al. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell. 94:1998;739-750
44. Demetriou M., Binkert C., Sukhu B., Tenenbaum H.C., Dennis J.W. Fetuin/alpha2-HS glycoprotein is a transforming growth factor-beta type II receptor mimic and cytokine antagonist. J. Biol. Chem. 271:1996;12755-12761
45. Datto M.B., Frederick J.P., Pan L., Borton A.J., Zhuang Y., Wang X.F. Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. Mol. Cell Biol. 19:1999;2495-2504
46. Muller-Rover S., Handjiski B., van der Veen C., Eichmuller S., Foitzik K., McKay I.A. A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages. J. Invest. Dermatol. 117:2001;3-15
47. Trueb R.M. Molecular mechanisms of androgenetic alopecia. Exp. Gerontol. 37:2002;981-990
48. Sawaya M.E., Price V.H. Different levels of 5-alpha-reductase types I and II, aromatase, and androgen receptor in hair follicles of women and men with androgenetic alopecia. J. Invest. Dermatol. 109:1997;296-300
49. Sawaya M.E. Biochemical mechanisms regulating human hair growth. Skin Pharmacol. 7:1994;5-7
50. Kaufman K.D., Olsen E.A., Whiting D., Savin R., DeVillez R., Bergfeld W., et al. Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group. J. Am. Acad. Dermatol. 39:1998;578-589
51. Sawaya M.E., Penneys N.S. Immunohistochemical distribution of aromatase and 3β-hydroxysteroid dehydrogenase in human hair follicle and sebaceous gland. J. Cutan. Pathol. 19:1992;309-314
52. Inui S., Fukuzato Y., Nakajima T., Yoshikawa K., Itami S. Androgen-inducible TGF-beta1 from balding dermal papilla cells inhibits epithelial cell growth: a clue to understand paradoxical effects of androgen on human hair growth. Faseb. J. 16:2002;1967-1969
53. Shang Y., Myers M., Brown M. Formation of the androgen receptor transcription complex. Mol. Cell. 9:2002;601-610
54. Nessler-Menardi C., Jotova I., Culig Z., Eder I.E., Putz T., Bartsch G., et al. Expression of androgen receptor coregulatory proteins in prostate cancer and stromal-cell culture models. Prostate. 45:2000;124-131
55. Markus S.M., Taneja S.S., Logan S.K., Li W., Ha S., Hittelman A.B., et al. Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus. Mol. Biol. Cell. 13:2002;670-682
56. Muller J.M., Isele U., Metzger E., Rempel A., Moser M., Pscherer A., et al. FHL2, a novel tissue-specific coactivator of the androgen receptor. EMBO J. 19:2000;359-369
57. Andersson S. Steroidogenic enzymes in skin. Eur. J. Dermatol. 11:2001;293-295