Glyco-optimization of aminoglycosides: New aminoglycosides as novel anti-infective agents

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 14, 2004, Pages 3733-3738

  Yao, Sulan ^a   Sgarbi, Paulo W M ^a   Marby, Kenneth A ^a   Rabuka, David ^a   O'Hare, Sean M ^a   Cheng, Mayling L ^a   Bairi, Mrunali ^a   Hu, Changyong ^b   Hwang, San Bao ^b   Hwang, Chan Kou ^a   Ichikawa, Yoshi ^a   Sears, Pamela ^a   Sucheck, Steven J ^a  

^a Optimer Pharmaceuticals Inc   (United States)

^b Singapore Science Park II   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE DERIVATIVE; ANTIINFECTIVE AGENT;

ANTIMICROBIAL ACTIVITY; ARTICLE; CROSS LINKING; DERIVATIZATION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; GLYCOSYLATION; GRAM NEGATIVE ANAEROBIC BACTERIA; PSEUDOMONAS AERUGINOSA; REACTION OPTIMIZATION; STATISTICAL SIGNIFICANCE; SUBSTITUTION REACTION;

AMINOGLYCOSIDES; ANTI-INFECTIVE AGENTS; DRUG DESIGN; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; TRISACCHARIDES;

EID: 2942588958     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.05.004     Document Type: Article

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