Involvement of calcium/calmodulin-dependent protein kinases in the setting of molecular switch involved in hippocampal LTP

Neuropharmacology

Volumn 37, Issue 4-5, 1998, Pages 535-544

  Bortolotto, Z A ^a   Collingridge, G L ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

AP5; CaMKII; Hippocampus; KN 62; Long term potentiation (LTP); MCPG; Memory; Metabotropic glutamate (mGlu) receptor

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; METABOTROPIC RECEPTOR; PROTEIN KINASE;

ANIMAL TISSUE; BRAIN SLICE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; HIPPOCAMPUS; IN VITRO STUDY; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; 2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; BENZOATES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; HIPPOCAMPUS; LONG-TERM POTENTIATION; MEMBRANE POTENTIALS; PERFUSION; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES;

EID: 0031781514     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(98)00058-6     Document Type: Conference Paper

References (45)

1. Anderson W.W., Collingridge G.L. A data acquisition program for on-line analysis of long-term potentiation and long-term depression. Neurosci. Abstr. 23:1997;665.
2. Barria A., Muller D., Derkach V., Griffith L.C., Soderling T.R. Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation. Science. 276:1997;2042-2045.
3. Bashir Z.I., Alford S., Davies S.N., Randall A.D., Collingridge G.L. Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus. Nature. 349:1991;156-158.
4. Bear M.F., Abraham W.C. Long-term depression in hippocampus. Annu. Rev. Neurosci. 19:1996;437-462.
5. Benke, T.A., Lüthi, A., Issac, J.T.R., Collingridge, G.L., 1998. Modulation of AMPA receptor unitary conductance by synaptic activity. Nature in press.
6. Blake J.F., Yates R.G., Brown M.W., Collingridge G.L. 6-Cyano-7-nitroquinoxaline-2,3-dione as an excitatory amino acid antagonist in area CA1 of rat hippocampus. Br. J. Pharmacol. 97:1988;71-76.
7. Bliss T.V.P., Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature. 361:1993;31-39.
8. Bortolotto Z.A., Collingridge G.L. An involvement of calcium/calmodulin protein kinase II (CaM-KII) in the molecular switch activated by mGluRs in rat hippocampal slices in vitro. J. Physiol. 504.P:1997;219P.
9. Bortolotto Z.A., Bashir Z.I., Davies C.H., Collingridge G.L. Metabotropic glutamate receptors activate a molecular switch which regulates the induction of long-term potentiation. Nature. 368:1994;740-743.
10. 2+/calmodulin-dependent kinase-II alpha-subunit mutation. Proc. Natl. Acad. Sci. USA. 92:1995;6852-6855.
11. Collingridge G.L., Kehl S.J., McLennan H. Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus. J. Physiol. 334:1983;33-46.
12. Davies S.N., Lester R.A.J., Reymann K.G., Collingridge G.L. Temporally distinct pre- and post-synaptic mechanisms maintain long-term potentiation. Nature. 338:1989;500-503.
13. Ehlers M.D., Zhang S., Bernhardt J.P., Huganir R.L. Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit. Cell. 84:1996;745-755.
14. 2+/calmodulin-dependent protein kinase II. J. Biol. Chem. 268:1993;7863-7867.
15. 2+/calmodulin-dependent protein kinase II and its endogenous substrates in the induction of long term potentiation. J. Biol. Chem. 270:1995;6119-6124.
16. Hidaka H., Yokokura H. Molecular and cellular pharmacology of a calcium/calmodulin-dependent protein kinase II (CaM Kinase II) inhibitor, KN-62, and proposal of CaM kinase phosphorylation cascades. Adv. Pharmacol. 36:1996;193-219.
17. Hvalby O., Hemmings H.C. Jr., Paulsen O., Czernik A.J., Nairn A.C., Godfraind J.-M., Jensen V., Raastad M., Storm J.F., Andersen P., Greengard P. Specificity of protein kinase inhibitor peptides and induction of long-term potentiation. Proc. Natl. Acad. Sci. USA. 91:1994;4761-4765.
18. Isaac J.T.R., Nicoll R.A., Malenka R.C. Evidence for silent synapses: implications for the expression of LTP. Neuron. 15:1995;427-434.
19. Ito I., Hidaka H., Sugiyama H. Effects of KN-62, a specific inhibitor of calcium/calmodulin-dependent protein kinase II, on long-term potentiation in the rat hippocampus. Neurosci. Lett. 121:1991;119-121.
20. Kennedy M.B., Bennett M.K., Erondu N.E. Biochemical and immunochemical evidence that the 'major postsynaptic density protein' is a subunit of a calmodulin-dependent protein kinase. Proc. Natl. Acad. Sci. USA. 80:1983;7357-7361.
21. Liao D., Hessler N.A., Malinow R. Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice. Nature. 375:1995;400-404.
22. Lisman J. The CaM kinase II hypothesis for the storage of synaptic memory. Trends Pharmacol. Sci. 17:1994;406-412.
23. 2+/calmodulin-dependent protein kinase molecules of the postsynaptic density. Proc. Natl. Acad. Sci. USA. 85:1988;5320-5324.
24. Lledo P.M., Hjelmstad G.O., Mukherji S., Soderling T.R., Malenka R.C., Nicoll R.A. Calcium/calmodulin-dependent kinase II and long-term potentiation enhance synaptic transmission by the same mechanism. Proc. Natl. Acad. Sci. USA. 92:1995;11175.
25. Malenka R.C., Kauer J.A., Perkel D.J., Mauk M.D., Kelly P.T., Nicoll R.A. An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation. Nature. 340:1989;554-557.
26. Malinow R., Schulman H., Tsien R.W. Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP. Science. 245:1989;862-866.
27. Manzoni O.J., Weisskopf M.G., Nicoll R.A. MCPG antagonises metabotropic glutamate receptors but not long-term potentiation in the hippocampus. Eur. J. Neurosci. 6:1994;1050-1054.
28. Mayford, M., Wang, J., Kandel, E.R., O'Dell, T., 1995. CaMKII regulates the frequency-response function of hippocampal synapses for the production of both LTD and LTP. Cell 81, 891-904.
29. 2+-triggered molecular switch. Cell. 44:1986;861-870.
30. Minakami R., Jinnai N., Sugiyama H. Phosphorylation and calmodulin binding of the metabotropic glutamate receptor subtype 5 (mGluR5) are antagonistic in vitro. J. Biol. Chem. 272:1997;20291-20298.
31. 2+/calmodulin-dependent protein kinase II by inter- and intrasubunit-catalyzed autophosphorylations. J. Biol. Chem. 269:1994;13744-13747.
32. 2+/calmodulin-dependent kinase in intact hippocampal slices. Neuron. 6:1991;907-914.
33. Otmakhov N., Griffith L.C., Lisman J.E. Postsynaptic inhibitors of calcium/calmodulin-dependent protein kinase type II block induction but not maintenance of pairing-induced long-term potentiation. J. Neurosci. 17:1997;5357-5365.
34. Ouyang Y., Kantor D., Harris K.M., Schuman E.M., Kennedy M.B. Visualization of the distribution of autophosphorylated calcium/calmodulin-dependent protein kinase II after tetanic stimulation in the CA1 area of the hippocampus. J. Neurosci. 17:1997;5416-5427.
35. Pettit D.L., Periman S., Malinow R. Potentiated transmission and prevention of further LTP by increased CaMKII activity in postsynaptic hippocampal slice neurons. Science. 266:1994;1881-1885.
36. Richmond S.A., Irving A.J., Molnar E., McIlhinney R.A.J., Michelangeli F., Henley J.M., Collingridge G.L. Localisation of the glutamate receptor subunit GluR1 on the surface of living and within cultured hippocampal neurones. Neuroscience. 75:1996;69-82.
37. Roberson, E.D., English, J.D., Sweatt, J.D., 1996. Second messengers in LTP and LTD. In: Fazeli, M.F., Collingridge, G.L. (Eds.), Cortical Plasticity: LTP and LTD. βios Scientific Publishers, Oxford, pp. 35-60.
38. Selig D.K., Lee H.K., Bear M.F., Malenka R.C. Reexamination of the effects of MCPG on hippocampal LTP, LTD, and depotentiation. J. Neurophysiol. 74:1995;1075-1082.
39. Shirke A.M., Malinow R. Mechanisms of potentiation by calcium-calmodulin kinase II of postsynaptic sensitivity in rat hippocampal CA1 neurones. J. Neurophysiol. 78:1997;2682-2692.
40. Silva A.J., Stevens C.F., Tonegawa S., Wang Y. Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice. Science. 257:1992;201-206.
41. 2+/Calmodulin-dependent protein kinase II necessary for long-term potentiation and depression. J. Neurophysiol. 76:1996;2097-2101.
42. Tan S.-E., Wenthold R.J., Soderling T.R. Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulin-dependent protein kinase II and protein kinase C in cultured hippocampal neurones. J. Neurosci. 14:1994;1123-1129.
43. 2+/calmodulin-dependent protein kinase II. J. Biol. Chem. 265:1990;4315-4320.
44. 2+/CaM induces synaptic potentiation requiring CaMKII and PKC activity. Neuron. 15:1995;443-452.
45. Watkins J.C., Collingridge G.L. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors. Trends Pharmacol. Sci. 15:1994;333-342.