Cancer: A single disease with a multitude of manisfestions?

Journal of Carcinogenesis

Volumn 2, Issue , 2003, Pages

  Grandics, Peter ^a  

^a A D Research Foundation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; IODIDE; IODINE; LINOLEIC ACID; LIPID; MINERAL; MOLASSES; PANCREATIN; PHENOL DERIVATIVE; POLYPHENOL; POLYSACCHARIDE; QUININE; ROSE OIL; SULFUR; VITAMIN;

ANTINEOPLASTIC ACTIVITY; BREAST CARCINOMA; CANCER INCIDENCE; CANCER RESEARCH; CARCINOGENESIS; CELL PROLIFERATION; CLINICAL FEATURE; COLON CARCINOMA; CORRELATION ANALYSIS; DIETARY INTAKE; DNA INTEGRATION; ENVIRONMENTAL FACTOR; FOOD COMPOSITION; FOOD PREFERENCE; GEOGRAPHIC DISTRIBUTION; HYPOTHESIS; IMMUNE DEFICIENCY; INFLAMMATION; JAPAN; LUNG CARCINOMA; METAPLASIA; NONHUMAN; NUTRITION; NUTRITIONAL DEFICIENCY; NUTRITIONAL STATUS; OCCUPATIONAL HEALTH; PANCREAS ADENOCARCINOMA; RAT; REVIEW;

EID: 2942577522     PISSN: 14773163     EISSN: None     Source Type: Journal    
DOI: 10.1186/1477-3163-2-9     Document Type: Review

References (153)

1. von Koerber K, Mannle Th, Leitzmann C: Vollwert-Ernahrung. Haug Verlag, Heidelberg; 1993:S37-43.
2. Weisburger JH, Wynder EL: Dietary fat intake and cancer. Hematol Oncol Clin North Am 1991, 5(1):7-23.
3. Committee on Diet, Nutrition and Cancer: Diet, Nutrition and Cancer, The relationship between nutrients and cancer. Washington DC: National Academy Press 1982:51-66.
4. Feldman EB: Dietary intervention and chemoprevention-1992 perspective. Prev Med 1993, 22:661-666.
5. Bowen PE: Dietary intervention strategies: Validity, execution and interpretation of outcomes in Nutrition and Cancer Prevention. Edited under the auspices of AICR New York: Kluyver Academic/Plenum Publishers; 2000.
6. Rodler I, Zajkas G: Hungarian cancer mortality data and food availability in the last four decades of the 20th century. Nutr Metabol 2002, 46:49-56.
7. Kune S, Kune GA, Watson LF: Case-control study of dietary etiological factors: the Melbourne colorectal cancer study. Nutr Cancer 1987, 9:1-29.
8. Buell P: Changing incidence of breast cancer in Japanese-American woman. J Natl Cancer Inst 1973, 51:1479-1483.
9. Kolonel LN, Hankin JH, Lee J, Chu SY, Nomura AM, Hinds MW: Nutrient intakes in relation to cancer incidence in Hawaii. Br J Cancer 1981, 44:332-339.
10. Parkin DM, Pisani P, Ferlay J: Global cancer statistics. CA Cancer J Clin 1999, 49:33-64.
11. Tominaga S, Kuroishi T: An ecological study on diet/nutrition and cancer in Japan. Int J Cancer 1997, 10(suppl):2-6.
12. McMichael AJ, McCall MG, Hartshorne JM, Woodings TL: Patterns of gastrointestinal cancer in European migrants to Australia: the role of dietary change. Int J Cancer 1980, 25:431-437.
13. Le Marchand L, Hankin JH, Bach F, Kolonel LN, Stacewicz-Sapuntzakis M, Bowen PE, Beecher GR, Laudon F, Baque P, Daniel R, Seruvatu L, Henderson B: An ecological study of diet and lung cancer in the South Pacific. Int J Cancer 1995, 63:18-23.
14. Block G, Patterson B, Subar A: Fruit, vegetables and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 1986, 18:1-29.
15. Schapira DV: Diet, obesity, fat distribution and cancer in women. J Am Med Wom Assoc 1991, 46:126-130.
16. Carroll KK, Khor HT: Dietary fat in relation to tumorigenesis. Progr Biochem Pharmacol 1975, 10:308-353.
17. Negri E, D'Avanzo B, Tavani A: The role of vegetables and fruit in cancer risk. In Epidemiology of Diet and Cancer Edited by: Hill MJ, Giacosa A, Caygill CP. London: Ellis Horwood; 1994:327-334.
18. Doll R, Peto R: The cause of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst 1981, 66:1191-1308.
19. Kim YI: AGA technical review: impact of dietary fiber on colon cancer occurrence. Gastroenterology 2000, 118:1235-1257.
20. Burkin DS: Related disease-related cause? Lancet 1969, 2:1229-1231.
21. Department of Health (New Zeeland): Food for health. The report of the Nutrition Task Force to the Department of Health Wellington, NZ Department of Health; 1991.
22. Bacic A, Harris PJ, Stone BA: Structure and function of plant cell walls. In The Biochemistry of Plants, Carbohydrates Volume 14. Edited by: Preiss J. San Diego, CA: Academic; 1988:297-371.
23. Kroon PA, Faulds CB, Ryden P, Robertson JS, Williamson H: Release of covalently bound ferulic acid from fiber in the human colon. J Agric Food Chem 1996, 45:661-667.
24. Hudson EA, Dinh PA, Kokubun T, Simmonds MS, Gescher A: Characterization of potentially chemopreventive phenols in extracts of brown rice that inhibit the growth of human breast and colon cancer cells. Cancer Epidemiol Biomarkers Prev 2000, 9:1163-1170.
25. Ferguson LR, Harris PJ: Protection against cancer by wheat bran: role of dietary fibre and phytochemicals. Eur J Cancer Prev 1999, 8:17-25.
26. Ferguson LR: Role of plant polyphenols in genomic stability. Mutat Res 2001, 475:89-111.
27. Graham HN: Green tea composition, consumption and polyphenol chemistry. Prev Med 1992, 21:334-350.
28. Alberts DS, Martinez ME, Roe DJ, Guillen-Rodriguez JM, Marshall JR: Lack of effect high fiber cereal supplement on the recurrence of colorectal adenomas. Phoenix Colon Cancer Prevention Physician's Network. N Engl J Med 2000, 342:1156-1162.
29. Surh Y-J, Choo K-S, Cha H-H, Han SS, Keum YS: Molecular mechanism underlying chemopreventative activities of antiinflammatory phytochemicals: downregulation of COX-2 and iNOS through suppression of NF-kB activation. Mutat Res 2001, 480-48 1:243-268.
30. Chase AW: Practical Recipes Ann Arbor: Michigan; 1864:142.
31. Scott C: Crude black molasses New York: Benedict Lust Publications; 1980:23-63.
32. USDA Nutrient Database for Standard Reference. Release 13 Composition of Foods. Blackstrap molasses .
33. Scott C: Crude black molasses New York: Benedict Lust Publications; 1980:89.
34. Ames BA: DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutat Res 2001, 475:7-20.
35. Mee JML, Coy C, Stanley RW: Amino acid and fatty acid composition of cane molasses. J Food Sci Agric 1979, 30:429-432.
36. Serrano M, Thompson LU: The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis. Cancer Lett 1991, 60:135.
37. Thompson LU, Rickard SE, Orcheson LJ, Seidl MM: Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Carcinogenesis 1996, 17:1373-1376.
38. Fahey GC, Williams JE, McLaren GA: Influence of molasses lignin-hemicellulose fractions in rat nutrition. J Nutr 1976, 106:1447-1451.
39. Hegazy RA, El-Faramawy AA: Substitution of sugar cane bagasse in the chicken diet and immune response. Nahrung/Food 2001,45:364-367.
40. MRC Vitamin Study Research Group: Prevention of neural tube defects results of the Medical Research Council Vitamin Study. Lancet 1991, 338:131-137.
41. Daly LE, Kirke PN, Molloy A, Weir DG, Scott JM: Folate levels and neural tube defects. Implications for prevention. JAMA 1995, 274:1698-1702.
42. Kirke PN, Molloy A, Daly LE, Burke H, Weir DG, Scott JM: Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects. Q J Med 1993, 86:703-708.
43. Scott JM, Weir DG: Homocysteine and cardiovascular disease. Q J Med 1996, 89:561-563.
44. Selhub J, D'Angelo A: Relationship between homocysteine and thrombotic disease. Am J Med Sci 1998, 316:129-141.
45. Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM: Folate, vitamin B12 and total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 1998, 55:1449-1455.
46. Weir DG, Scott JM: Colonic mucosal folate concentrations and their association with colorectal cancer. Am J Clin Nutr 1998, 68:763-764.
47. Giovannucci E, Stampfer MJ, Colditz GA, Hunter DJ, Fuchs C, Rosner BA, Speizer FE, Willett WC: Multivitamin use, folate and colon cancer in women in the Nurse's health study. Ann Intern Med 1998, 129:517-524.
48. Almadori G, Bussu F, Galli J, Cadoni G, Zappacosta B,Persichilli S, Minucci A, Giardina B: Serum folate and homocysteine levels in head and neck squamous cell carcinoma. Cancer 2002,94:1006-1011.
49. Murr C, Berchtold J, Norer B, Waldhart E, Wachter H, Fuchs D: Neopterin as a prognostic parameter in patients with squamous cell carcinomas of the oral cavity. Int J Cancer 1998, 79:476-480.
50. Shrubsole MJ, Jin F, Dai Q, Shu X-O, Potter JD, Herbert JR, Gao Y-T, Zheng W: Dietary folate intake and breast cancer risk: Results from the Shanghai Breast Cancer Study. Cancer Res 2001, 61:7136-7141.
51. Scott JM, Weir DG: Folic acid, homocysteine and one-carbon metabolism: a review of essential biochemistry. J Cardiovas Risk 1998, 5:223-227.
52. Wickramashinge SN, Fida S: Misincorporation of uracil into the DNA of folate- and B12 deficient HL60 cells. Eur J Hematol 1993, 50:127-132.
53. James SJ, Basnakian AG, Miller BJ: In vitro folate deficiency induces deoxynucleotide pool imbalance, apoptosis and mutagenesis in Chinese hamster ovary cells. Cancer Res 1994, 54:5075-5080.
54. Paspatis GA, Kalafatis E, Oros L, Xourgias V, Koutsioumpa P, Karamanolis DG: Folate status and adenomatous colonic polyps: a colonoscopically controlled study. Dis Colon Rectum 1995, 38:64-68.
55. Bird CL, Swendseid ME, Witte JS, Shikany JM, Hunt IF, Frankl HD, Lee ER, Longnecker MP, Haile RW: Red cell and plasma folate, folate consumption, and the risk of colorectal adenomatous polyps. Cancer Epidemiol Biomarkers Prev 1995, 4:709-714.
56. Cravo M, Fidalgo P, Pereira AD, Gouveia-Oliveira A, Chaves P, Selhub J, Mason JB, Mira FC, Leitao CN: DNA methylations as an intermediary biomarker in colorectal cancer: modulation by folic acid supplementation. Eur J Cancer Prev 1994, 3:473-479.
57. Kim Y-I, Pogribny IP, Basnakian AG, Miller JW, Selhub J, James SJ, Mason JB: Folate deficiency in rats induces DNA strand breaks and hypomethylation within p53 tumor suppressor gene. Am J Clin Nutr 1997, 65:45-52.
58. Kim Y-I, Shirwadkar S, Choi S-W, Puchyr M, Wang Y, Mason JB: Effects of dietary folate on DNA strand breaks within mutation-prone exons of the p53 gene in the rat colon. Gastroenterology 2000, 119:151-161.
59. Cheah MS, Wallace CD, Hoffman RM: Hypomethylation of DNA in human cancer cells: a site specific change in the c-myc oncogene. J Natl Cancer Inst 1984, 73:1057-1061.
60. Goelz SE, Vogelstein B, Hamilton SR, Feinberg AP: Hypomethylation of DNA from benign and malignant human colon neoplasms. Science 1985, 228:187-190.
61. Adany R, Iozzo R: Hypomethylation of the decorin proteoglycan gene in human colon cancer. Biochem J 1991, 276:301-306.
62. Baylin SB, Herman JG: DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000, 16:168-174.
63. Feinberg AP, Vogelstein B: Hypomethylation of the ras oncogenes in primary human cancers. Biochem Biophys Res Commun 1983, 111:47-54.
64. Sharrard RM, Royds JA, Rogers S, Shorthouse AJ: Patterns of methylation of the c-myc gene in human colorectal cancer progression. Br J Cancer 1992, 65:667-672.
65. Keshet I, Lieman-Hurwitz J, Cedar H: DNA methylation affects the formation of active chromatin. Cell 1986, 44:535-543.
66. Lewis J, Bird A: DNA methylation and chromatin structure. FEBS Lett 1991, 285:155-159.
67. Jones PA, Laird PW: Cancer epigenetics coming of age. Nat Genet 1999, 21:163-167.
68. Morgan SL, Baggott JE, Vaughn WH, Austin JS, Veitch TA, Lee JY, Koopman WJ, Krumdieck CL, Alarcon GS: Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial. Ann Intern Med 1994, 121:833-841
69. Calvert H: Folate status and the safety of antifolates. Semin Oncol 2002, 29(suppl 5):3-7.
70. Barnard RD, Freeman MD: Reversal of aminopterin toxicity by water soluble cuprodihydroporphirins (chloresium). Am J Digest Dis 1954, 21:163-169.
71. Fenech M: Recommended dietary allowances for genomic stability. Mutat Res 2001, 480-481:51-54.
72. Heimburger DC, Alexander CB, Birch R, Butterworth CE Jr, Bailey WC, Krumdieck CL: Improvement in bronchial squamous cell metaplasia in smokers treated with folic acid and vitamin B-12. Report of a preliminary randomized, double-blind intervention trial. JAMA 1988, 259:1525-1530.
73. Saito M, Kato H, Tsuchida T, Konaka C: Chemoprevention effects on bronchial squamous metaplasia by folate and vitamin B-12. Chest 1994, 106:496-499.
74. Senti FR, Pilch SM: Analysis of folate data from the second national Health and Nutrition Examination Survey (NHANES II). J Nutr 1985, 115:1398-1402.
75. Subar AF, Block G, James LD: Folate intake and food sources in the US population. Am J Clin Nutr 1989, 50:508-516.
76. Wilson JW, Enns CW, Goldman JD, Tippett KS, Mickle SJ, Cleveland LE, Chahil PS: Data tables: Combined results from USDA's 1994 and 1995 continuing survey of food intakes by individuals and 1994 and 1995 diet and healthy knowledge survey. USDA/ARS Food Survey Research Group, Beltsville Human Nutrition Research Center, Riverdale, MD. .
77. van Asselt DZ, de Groot LC, van Staveren WA, Blom HJ, Wevers RA, Biemond I, Hoefnagels WH: Role of cobalamine intake and atrophic gastritis in mild cobalamine deficiency in older Dutch subjects. Am J Clin Nutr 1998, 68:328-334.
78. Levander OA, Burk RF: Selenium. in Present Knowledge in Nutrition. Edited by: Ziegler EE, Filer LJ. Washington DC: ILSI Press; 1996:320-328.
79. Foster HD: Disease family trees: the possible roles of iodine in goiter, cretinism, multiple sclerosis, amyothropic lateral sclerosis, Alzheimer's and Parkinson's diseases and cancer of the thyroid, nervous system and skin. Med Hypothesis 1987, 24:249-263.
80. Boyages SC, Collins JK, Maberly GF, Jupp JJ, Morris J, Eastman CJ: Iodine deficiency impairs intellectual and neuromotor development in apparently-normal person: a study of rural inhabitants of North-central China. Med J Australia 1989, 150:676-682.
81. Laurberg P, Pedersen KM, Hreidarsson A, Sigfusson N, Iversen E, Knudsen PR: Iodine intake and the pattern of thyroid disorders: A comparative epidemiological study of thyroid abnormalities in the elderly in Iceland and Jutland, Denmark. J Clin Endocrinol Metab 1998, 83:765-769.
82. Galanti MR, Sparen P, Karlsson A, Grimelius L, Ekbom A: Is residence in areas of endemic goitre a risk factor for thyroid cancer? Int J Cancer 1995, 61:615-621.
83. Franchesci S: Iodine intake and thyroid carcinoma-A potential risk factor. Exp Clin Endocrinol Diabetes 1997, 106(Suppl 3):S38-S44.
84. Kalk WJ, Sitas F, Patterson AC: Thyroid cancer in South Africa-an indicator of regional iodine deficiency. S Afr Med J 1997, 87:731-733.
85. Ohshima M, Ward JM: Dietary iodine deficiency as a tumor promoter and carcinogen in F334/Ncr male rats. Cancer Res 1986, 46:877-883.
86. Eskin BA: Iodine and mammary cancer. Adv Exp Med Biol 1977, 91:293-304.
87. Eskin BA: Iodine metabolism and breast cancer. NY Acad Sci 1970, 32:911-947.
88. Mittra I, Hayward JL: Hypothalamic-pituitary-thyroid axis in breast cancer. Lancet 1(7863):885-889. 1974 May 11
89. Spencer JM: Geological influences on regional health problems. Texas J Sci 1970, 21:459-469.
90. Parker SL, Tong T, Bolden S, Wingo PA: Cancer statistics. CA Cancer J Clin 1997, 47:5-27.
91. Ghent WR, Eskin BA, Low DA, Hill LP: Iodine replacement in fibrocystic disease. Can J Surg 1993, 36:453-460.
92. Phillips DI, Lusty TD, Osmond C, Church D: Iodine supplementation: Comparison of oral or intramuscular iodized oil vs oral potassium iodide. A controlled trial in Zaire. Int J Epidemiol 1988, 17:142-147.
93. Dugrillon A: Iodolactones and iodoaldehydes-mediators of iodine in thyroid autoregulation. Exp Clin Endocrinol Diabetes 1996, 104(suppl 4):41-45.
94. Pharmacopoiea of the United States, Eight Decennial Revision 1905:250.
95. Serra-Majem LL, Tresserras R, Canela J, Salleras L: Dietary iodine deficiency and breast cancer mortality: an ecological study. Int J Epidemiol 1988, 17:686-687.
96. Zhang D-Z: The treatment of cancer by integrated Chinese-Western medicine. Boulder CO: Blue Poppy Press; 1989:21-43.
97. Zaichick VY, Tsyb A, Vtyurin BM: Trace elements and thyroid cancer. Analyst 1995, 120:817-821.
98. Kato N, Funahashi H, Ando K, Takagi H: Suppressive effects of iodine preparations on proliferation of DMBA-induced breast cancer in rat. J Jpn Soc Cancer Ther 1994, 29:582-588.
99. Funahashi H, Imai T, Tanaka Y, Tobinaga J, Wada M, Morita T, Yamada F, Tsukamura K, Oiwa M, Kikumori T, Narita T, Takagi H: Suppressive effect of iodine on DMBA-induced breast tumor growth in the rat. J Surgical Oncol 1996, 61:209-213.
100. Lofti M, Mason JB: The prevention and control of iodine deficiency disorders. ACC/SCN Nutrition Policy Discussion Paper No. 3, 7: United Nations. .
101. Marani L, Venturi S, Masala R: Role of iodine in delayed immune response. Isr J Med Sci 1985, 21:864.
102. Weetman AP, McGregor AM, Campbell H, Lazarus JH, Ibberson HK, Hall R: Iodine enhances IgG synthesis by human peripheral blood lymphocytes in vitro. Acta Endocr (Copenh) 1983, 103:210-215.
103. Lee AKY, Rowley M, Mackay IR: Antibody-producing capacity in human cancer. Br J Cancer 1970, 24:454-63.
104. Als C, Lauber K, Brander L, Luscher D, Rosler H: The instability of dietary iodine supply over time in an affluent society. Experientia 1995, 51:623-633.
105. Ozcan M: Nutrient composition of rose (Rosa canina L.) seed and oils. J Med Food 2002, 5:137-140.
106. Discover Ayurveda Health Goals, The Ayurvedic view on roses and health [http://www.discoverayurveda.com/health/health_roses.html]
107. Umezu T: Behavioral effects of plant-derived essential oils in the Geller type conflict test in mice. Jpn J Pharmacol 2000, 83:150-153.
108. Boyanova L, Neshev G: Inhibitory effect of rose oil products on Helicobacter pylori growth in vitro: preliminary report. J Med Microbiol 1999, 48:705-706.
109. Lad V: The complete book of Ayurvedic home remedies New York: Three Rivers Press; 1998:209-211.
110. Beard J: The action of trypsin upon the living cells of Jensen's mouse tumor. Br Med J 1906, 4:140-141.
111. Wiggin PH: Case of multiple fibrosarcoma of the tongue, with remarks on the use of trypsin and amylopsin in the treatment of malignant disease. JAMA 1906, 47:2003-2008.
112. Cutfield A: Trypsin treatment of malignant disease. Br Med J 1907, 5:525.
113. Campbell JT: Trypsin treatment of a case of malignant disease. JAMA 1907, 48:225-226.
114. Little WL: A case of malignant tumor, with treatment. JAMA 1908, 50:1724.
115. King LS: Prevention of virus-induced mammary tumors by an orally active pancreas factor. Exp Med Surg 1965, 23:345-347.
116. King LS: A novel method of enhancing antibody production. Southwest Med 1965, 46:222-224.
117. Gotze H, Rothman SS: Enteropancreatic circulation of digestive enzymes as a conservative mechanism. Nature 1975, 257:607-609.
118. Liebow C, Rothman SS: Enteropancreatic circulation of digestive enzymes. Science 1975, 189:472-474.
119. Kelley WD: One answer to cancer: An ecological approach to the successful treatment of malignancy Pomeroy WA: Health Research Books; 1967.
120. Gonzalez NJ, Isaacs LL: Evaluation of pancreatic proteolytic enzyme treatment of adenocarcinoma of the pancreas, with nutrition and detoxification support. Nutr Cancer 1999,33:117-124.
121. Bastedo WA: Colon irrigation. JAMA 1932, 98:734-736.
122. Friedenwald J, Morrison S: Value, indications, limitations and technic of colonic irrigations. Med Clin North Am 1935:1611-1629.
123. Snyder RG: The value of colonic irrigation in counteracting auto-intoxication of intestinal origin. Med Clin North Am 1939:781-788.
124. Malagelada GF Jr: Gut flora in health and disease. Lancet 2003, 361(9356):512-519.
125. Hill MJ: Diet and the human intestinal bacterial flora. Cancer Res 1981, 41(9 Pt2):3778-3780.
126. Mallett AK, Rowland IR: Factors affecting the gut microflora. In Role of the Gut Flora in Toxicity and Cancer Edited by: Rowland IR. London: Academic; 1988:347-382.
127. van der Werf SD, Nagengast FM, van Berge Henegouwen GP, Huijbregts AW, van Tonergen JH: Intracolonic environment and the presence of colonic adenomas in man. Gut 1983, 24:876-880.
128. Vargo D, Moskovitz M, Floch MH: Faecal bacterial flora in cancer of the colon. Gut 1980, 21:701-705.
129. Noureldin MS, Shaltout AA, El Hamshary EM, Ali ME: Opportunistic intestinal protozoal infections in immunocompromised children. J Egypt Soc Parasitol 1999, 29:951-961.
130. Adel-Rahim AY: Parasitic infections and hepatic neoplasia. Dig Dis 2001, 19:288-291.
131. Fiorini M, Messina MF, Barrachia A: Peripherial intramonocytic and intraneutrophil leishmanias observed in chronic myelomonocytic leukemia (CMMoL) patient. Hematologica 2002, 87:EIM21.
132. Goodman LS, Gilman A: The Pharmacological Basis of Therapeutics New York: Macmillan Publishing Co; 1970:1057-1058.
133. Council of the Pharmaceutical Society of Great Britain: British Pharmaceutical Codex The Pharmaceutical Press; 1968:813.
134. Bragg PC, Bragg P: Apple Cider Vinegar Health Science; 1997.
135. Reich W: The Orgone accumulator. The Cancer Biopathy Volume 2. New York: Farrah, Strauss and Giroux; 1973:108-150.
136. Muschenic S, Gerbauer R: The (Psycho-)Physiological effects of the Reich orgone energy accumulator. Dissertation University of Marburg, West Germany; 1985.
137. Lassek H: Vegeto-Orgontherapie nach Wilhelm Reich. Natural Healing Methods for the European Community, Doc. Reg. V.5, Min. of Tech., Niedersachen, Univ. Lueneburg, Germany 1991.
138. Reich W: The carcinomatous shrinking biopathy. The Cancer Biopathy Volume 2. New York: Farrah Strauss and Giroux;; 1973:151-212.
139. Scurry MT, Levin EM: Psychosocial factors related to the incidence of cancer. Int J Psychiatry Med 1979, 9:159-177.
140. Baltrusch HJ, Waltz M: Cancer from a biobehavioural and social epidemiological perspective. Soc Sci Med 1985, 20:789-794.
141. Irwin M, Daniels M, Risch SC, Bloom E, Weiner H: Plasma cortisol and natural killer cell activity during bereavement. Biol Psychiatry 1988, 24:173-178.
142. Lissoni P, Cangemi P, Pirato D, Roselli MG, Rovelli F, Brivio F, Malugani F, Maestroni GJ, Conti A, Laudon M, Malysheva O, Giani L: A review on cancer-psychospiritual status interactions. Neuroendocrinol Lett 2001, 22:175-180.
143. Gottesman MM, Pastan I: Biochemistry of multidrug resistance mediated by the multidrug transporter. Ann Rev Biochem 1993, 62:385-427.
144. Shapiro AB, Ling V: Using purified P-glycoprotein to understand multidrug resistance. J Bioeng Biomembr 1995, 27:7-13.
145. Solary E, Velay I, Chauffert B, Bidan JM, Caillot D, Dumas M, Guy H: Sufficient levels of quinine in serum circumvent the multidrug resistance of leukemic cell line K562/ADM. Cancer 1991, 68:1714-1719.
146. Gala JL, Noel H, Rodhain J, Ma DFF, Ferrant A: P-glycoprotein positive, drug resistant invasive lymphoepithelial thymoma: treatment response to chemotherapy with cyclosporin and quinine. J Clin Pathol 1995, 48:679-681.
147. Solary E, Caillot D, Chauffert B, Casanovas RO, Dumas M, Maynadie M, Guyt H: Feasibility of using quinine, a potential multidrug resistance-reversing agent, in combination with mitoxantrone and cytarabine for the treatment of acute leukemia. J Clin Oncol 1992, 11:1730-1736.
148. Gold EF, Ben-Efraim S: Selective killing of mitogen-induced transformed cells by quinine sulfate in vitro. Int Arch Allergy Appl Immunol 1978, 57:177-182.
149. Chase AW: Practical Recipes Ann Arbor: Michigan; 1864:85-86.
150. Tate K: Old-Time Home Remedies. In house of the White Birches. Berne IN; 1998:128-129.
151. Passegue E, Jamieson CH, Ailles LE, Weissman IL: Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc Natl Acad Sci USA 2003, 100(Suppl 1):11842-11849.
152. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, Squire J, Dirks PB: Identification of a cancer stem cell in human brain tumors. Cancer Res 2003, 63:5821-5828.
153. Dick JE: Breast cancer stem cells revealed. Proc Natl Acad Sci USA 2003, 100:3547-3549.